Motif ID: Sox13

Z-value: 0.290


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_1334244040.298.6e-02Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 2.951 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_+_96210107 1.743 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr1_+_19103022 1.694 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr18_+_69593361 0.991 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr8_-_11008458 0.792 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr2_+_25180737 0.735 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr12_+_36314160 0.696 ENSMUST00000041407.5
 Sostdc1
sclerostin domain containing 1
chr7_-_132813095 0.466 ENSMUST00000106165.1
 Fam53b
family with sequence similarity 53, member B
chr2_-_36104060 0.466 ENSMUST00000112961.3
ENSMUST00000112966.3
 Lhx6

LIM homeobox protein 6

chr18_+_64887690 0.421 ENSMUST00000163516.1
 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr3_+_34649987 0.375 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr17_-_68004075 0.368 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr18_+_37355271 0.341 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr5_-_8367982 0.317 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
 Adam22






a disintegrin and metallopeptidase domain 22






chr1_-_93101825 0.317 ENSMUST00000112958.2
 Kif1a
kinesin family member 1A
chr3_+_60501252 0.266 ENSMUST00000099087.2
 Mbnl1
muscleblind-like 1 (Drosophila)
chr7_-_105787567 0.243 ENSMUST00000144189.1
 Dchs1
dachsous 1 (Drosophila)
chr15_-_50890396 0.206 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr7_+_24271568 0.204 ENSMUST00000032696.6
 Zfp93
zinc finger protein 93
chr14_-_121698417 0.153 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr11_-_77489666 0.148 ENSMUST00000037593.7
ENSMUST00000092892.3
 Ankrd13b

ankyrin repeat domain 13b

chr10_-_116473418 0.143 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr14_-_47568427 0.128 ENSMUST00000042988.6
 Atg14
autophagy related 14
chr15_-_91049823 0.115 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
 Kif21a




kinesin family member 21A




chr4_+_48585276 0.113 ENSMUST00000123476.1
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_+_103143052 0.089 ENSMUST00000106855.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr2_-_119662756 0.087 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
 Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr9_-_75597643 0.086 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr13_-_66851513 0.082 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr17_+_24886643 0.081 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
 Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr10_-_53647080 0.077 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr2_+_176236860 0.075 ENSMUST00000166464.1
 2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr7_-_84679346 0.072 ENSMUST00000069537.2
ENSMUST00000178385.1
 Zfand6

zinc finger, AN1-type domain 6

chr1_+_17145357 0.052 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr1_+_39900883 0.043 ENSMUST00000163854.2
ENSMUST00000168431.1
 Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr3_-_96058446 0.042 ENSMUST00000015891.5
 Vps45
vacuolar protein sorting 45 (yeast)
chr14_+_79515618 0.028 ENSMUST00000110835.1
 Elf1
E74-like factor 1
chr13_-_66852017 0.004 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr4_+_48585135 0.001 ENSMUST00000030032.6
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 0.7 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.2 3.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.0 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.1 0.8 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 1.7 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.4 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.0 REACTOME_MYOGENESIS Genes involved in Myogenesis