Motif ID: Sox14

Z-value: 0.877


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_998761930.048.1e-01Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 7.678 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_+_62965560 4.004 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr12_+_109546333 3.343 ENSMUST00000166636.2
Meg3
maternally expressed 3
chr4_+_13751297 3.269 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_6980376 3.087 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr12_+_109546409 3.041 ENSMUST00000143847.1
Meg3
maternally expressed 3
chr4_+_102254739 2.965 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr13_-_58113592 2.746 ENSMUST00000160860.1
Klhl3
kelch-like 3
chr11_+_67586675 2.669 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr9_+_65265173 2.473 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr12_+_109545390 2.444 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr11_+_67586520 2.444 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chrX_-_167209149 2.271 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr14_-_104467984 2.238 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr14_-_98169542 2.224 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr2_-_102186322 2.205 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr11_-_12037391 1.971 ENSMUST00000093321.5
Grb10
growth factor receptor bound protein 10
chr12_-_32061221 1.965 ENSMUST00000003079.5
ENSMUST00000036497.9
Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

chr13_+_5861489 1.944 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr13_-_14523178 1.830 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr13_+_93304940 1.726 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr16_+_52031549 1.725 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr15_+_88751649 1.707 ENSMUST00000041297.8
Zbed4
zinc finger, BED domain containing 4
chr2_+_143546144 1.677 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr6_-_99028251 1.670 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr1_+_146497614 1.594 ENSMUST00000132847.1
ENSMUST00000166814.1
Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr12_-_10900296 1.580 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr7_-_144939823 1.544 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr1_+_131962941 1.474 ENSMUST00000177943.1
Slc45a3
solute carrier family 45, member 3
chr10_+_37139558 1.446 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr1_-_12991109 1.438 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr11_+_24076529 1.397 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr15_-_95528702 1.387 ENSMUST00000166170.1
Nell2
NEL-like 2
chr15_-_95528228 1.377 ENSMUST00000075275.2
Nell2
NEL-like 2
chr18_-_43393346 1.373 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr6_-_82774448 1.311 ENSMUST00000000642.4
Hk2
hexokinase 2
chr16_-_96082513 1.301 ENSMUST00000113827.1
Brwd1
bromodomain and WD repeat domain containing 1
chr11_+_119022962 1.236 ENSMUST00000026662.7
Cbx2
chromobox 2
chr2_+_3114220 1.220 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr6_-_48445678 1.216 ENSMUST00000114556.1
Zfp467
zinc finger protein 467
chr14_-_7483762 1.193 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr14_+_59201418 1.188 ENSMUST00000140136.2
ENSMUST00000142326.1
Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr18_-_46198810 1.176 ENSMUST00000167364.1
Trim36
tripartite motif-containing 36
chr8_+_36993551 1.168 ENSMUST00000098825.3
AI429214
expressed sequence AI429214
chr11_-_69822144 1.145 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr12_+_31265279 1.132 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr7_+_90426312 1.130 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr13_-_102905740 1.122 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr6_+_120666388 1.108 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr3_+_55461758 1.090 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr3_-_88458876 1.078 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr3_-_88459047 1.076 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr3_-_33083016 1.034 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr19_-_57118897 0.972 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr8_+_45507768 0.966 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr5_-_28467093 0.954 ENSMUST00000002708.3
Shh
sonic hedgehog
chr8_-_105289465 0.946 ENSMUST00000171788.1
ENSMUST00000014981.6
4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr9_+_53771499 0.941 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr5_-_142906702 0.939 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr3_-_127837419 0.926 ENSMUST00000051737.6
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr6_-_48445373 0.921 ENSMUST00000114563.1
ENSMUST00000114558.1
ENSMUST00000101443.3
ENSMUST00000114564.1
Zfp467



zinc finger protein 467



chr2_-_27426992 0.914 ENSMUST00000056176.7
Vav2
vav 2 oncogene
chr12_+_31265234 0.910 ENSMUST00000169088.1
Lamb1
laminin B1
chr13_+_93304799 0.896 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr13_-_23745511 0.888 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr6_+_54039558 0.885 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr18_-_46212595 0.882 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr19_-_57118981 0.881 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr17_-_79355082 0.879 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr1_-_60566708 0.873 ENSMUST00000027168.5
ENSMUST00000090293.4
ENSMUST00000140485.1
Raph1


Ras association (RalGDS/AF-6) and pleckstrin homology domains 1


chr5_-_110387090 0.870 ENSMUST00000056124.6
Fbrsl1
fibrosin-like 1
chr2_+_120476911 0.860 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr2_-_132111440 0.852 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr1_+_134182404 0.847 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr17_-_28486082 0.843 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr10_-_29144194 0.837 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr3_+_65109343 0.818 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chrX_-_136993027 0.804 ENSMUST00000171738.1
ENSMUST00000056674.5
ENSMUST00000129807.1
Slc25a53


solute carrier family 25, member 53


chr13_-_89742244 0.804 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr11_-_78165521 0.792 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr1_+_17727034 0.792 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr3_-_105053125 0.785 ENSMUST00000077548.5
Cttnbp2nl
CTTNBP2 N-terminal like
chr12_-_112829351 0.783 ENSMUST00000062092.5
Cdca4
cell division cycle associated 4
chr4_+_128727585 0.770 ENSMUST00000106079.3
ENSMUST00000133439.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr9_-_35570393 0.768 ENSMUST00000115110.4
Hyls1
hydrolethalus syndrome 1
chr1_+_193173469 0.766 ENSMUST00000161235.1
ENSMUST00000110831.2
ENSMUST00000178744.1
A130010J15Rik


RIKEN cDNA A130010J15 gene


chr10_+_45067167 0.757 ENSMUST00000099858.2
Prep
prolyl endopeptidase
chr12_-_86726439 0.732 ENSMUST00000021682.8
Angel1
angel homolog 1 (Drosophila)
chr1_+_134182150 0.729 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr12_-_54986328 0.718 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr2_+_178141920 0.716 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr5_-_50058908 0.716 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr2_-_103797617 0.707 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr6_-_29212240 0.703 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr9_-_70503718 0.696 ENSMUST00000034739.5
Rnf111
ring finger 111
chr10_+_80150448 0.693 ENSMUST00000153477.1
Midn
midnolin
chr15_+_99702278 0.687 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr19_+_40831248 0.682 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chr4_+_57434247 0.671 ENSMUST00000102905.1
Palm2
paralemmin 2
chr11_+_69045640 0.669 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr12_+_108605757 0.664 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr12_-_54986363 0.663 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr13_+_21810428 0.655 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr7_+_64501949 0.646 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr8_+_22757744 0.644 ENSMUST00000033941.5
Plat
plasminogen activator, tissue
chr14_-_60197173 0.643 ENSMUST00000131670.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr14_-_121698417 0.640 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9
chr16_+_17144600 0.637 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr5_+_108065696 0.633 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr11_-_69672307 0.633 ENSMUST00000163666.2
Eif4a1
eukaryotic translation initiation factor 4A1
chr10_+_80151154 0.630 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr4_-_49593875 0.622 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr11_-_98022594 0.617 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
Cacnb1



calcium channel, voltage-dependent, beta 1 subunit



chr2_+_119618717 0.609 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr2_-_181314500 0.598 ENSMUST00000103045.3
Stmn3
stathmin-like 3
chr12_-_99883429 0.598 ENSMUST00000046485.3
Efcab11
EF-hand calcium binding domain 11
chr9_-_60687459 0.597 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
Lrrc49


leucine rich repeat containing 49


chr12_+_100110148 0.594 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr2_-_85196697 0.594 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr2_+_104590453 0.591 ENSMUST00000028599.7
Cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr5_+_33995984 0.582 ENSMUST00000056355.8
Nat8l
N-acetyltransferase 8-like
chr19_-_4943049 0.581 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
Peli3


pellino 3


chr3_+_90079540 0.580 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr9_-_9239019 0.561 ENSMUST00000183182.1
Arhgap42
Rho GTPase activating protein 42
chr6_-_50261743 0.557 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
Dfna5


deafness, autosomal dominant 5 (human)


chr3_-_105052948 0.555 ENSMUST00000098763.2
Cttnbp2nl
CTTNBP2 N-terminal like
chr11_-_76577701 0.553 ENSMUST00000176179.1
Abr
active BCR-related gene
chr19_+_40831296 0.544 ENSMUST00000119316.1
Ccnj
cyclin J
chr2_+_32876114 0.544 ENSMUST00000028135.8
Fam129b
family with sequence similarity 129, member B
chrX_-_53269786 0.535 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr9_+_98422961 0.534 ENSMUST00000052068.9
Rbp1
retinol binding protein 1, cellular
chr3_+_146500071 0.530 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chrX_+_101429555 0.528 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr12_-_108835845 0.527 ENSMUST00000021693.3
Slc25a29
solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29
chr4_-_6990774 0.526 ENSMUST00000039987.3
Tox
thymocyte selection-associated high mobility group box
chr2_+_181763315 0.526 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr19_-_37178011 0.525 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr13_+_21716385 0.523 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr16_+_90386382 0.514 ENSMUST00000065856.6
Hunk
hormonally upregulated Neu-associated kinase
chr17_-_70853482 0.509 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr8_-_47713920 0.502 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr13_+_93304066 0.499 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr17_-_35838259 0.492 ENSMUST00000001566.8
Tubb5
tubulin, beta 5 class I
chr17_-_35838208 0.488 ENSMUST00000134978.2
Tubb5
tubulin, beta 5 class I
chr15_+_100038635 0.487 ENSMUST00000100203.3
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr5_+_108065742 0.486 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr9_-_60688118 0.485 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr10_-_37138863 0.481 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr4_-_108833544 0.479 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr7_-_121035096 0.474 ENSMUST00000065740.2
Gm9905
predicted gene 9905
chr4_+_127021311 0.469 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr1_+_65186727 0.454 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr13_-_34130345 0.439 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr2_-_18048347 0.437 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr4_-_129227883 0.437 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr4_-_136602641 0.429 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a

lysine (K)-specific demethylase 1A

chr7_-_105574324 0.426 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr7_+_64501687 0.423 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr10_-_125328957 0.419 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr10_+_80300997 0.415 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr4_-_109202217 0.413 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr18_-_14682756 0.404 ENSMUST00000040964.6
ENSMUST00000092041.3
ENSMUST00000040924.7
Ss18


synovial sarcoma translocation, Chromosome 18


chr9_+_107569112 0.403 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr5_-_118244861 0.400 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr1_+_153899937 0.394 ENSMUST00000086199.5
Glul
glutamate-ammonia ligase (glutamine synthetase)
chrX_+_93654863 0.393 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr8_+_92357787 0.392 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr8_-_90348126 0.384 ENSMUST00000176034.1
ENSMUST00000176616.1
Tox3

TOX high mobility group box family member 3

chr4_-_135272798 0.384 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr4_-_132212060 0.376 ENSMUST00000085181.4
Ythdf2
YTH domain family 2
chr4_+_53779694 0.374 ENSMUST00000030124.3
Tal2
T cell acute lymphocytic leukemia 2
chr7_+_24530645 0.369 ENSMUST00000049020.7
Irgq
immunity-related GTPase family, Q
chr14_+_31134853 0.366 ENSMUST00000090212.4
Nt5dc2
5'-nucleotidase domain containing 2
chr11_+_20201406 0.362 ENSMUST00000020358.5
ENSMUST00000109602.1
ENSMUST00000109601.1
Rab1


RAB1, member RAS oncogene family


chr4_+_59626189 0.356 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr4_+_101647763 0.354 ENSMUST00000106927.1
Leprot
leptin receptor overlapping transcript
chr2_-_86347764 0.352 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr8_+_123653903 0.346 ENSMUST00000045487.3
Rhou
ras homolog gene family, member U
chr5_-_115272883 0.342 ENSMUST00000040555.8
ENSMUST00000112096.2
ENSMUST00000112097.1
Rnf10


ring finger protein 10


chr10_+_75060885 0.337 ENSMUST00000164107.1
Bcr
breakpoint cluster region
chr17_-_32284088 0.332 ENSMUST00000119123.1
ENSMUST00000003726.8
ENSMUST00000121285.1
ENSMUST00000120276.1
ENSMUST00000114475.2
Brd4




bromodomain containing 4




chr17_-_59013264 0.332 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr4_+_101647712 0.328 ENSMUST00000030254.8
Leprot
leptin receptor overlapping transcript
chr5_-_8622855 0.327 ENSMUST00000047485.8
ENSMUST00000115378.1
Rundc3b

RUN domain containing 3B

chr9_+_40801235 0.325 ENSMUST00000117870.1
ENSMUST00000117557.1
Hspa8

heat shock protein 8

chr1_+_133045984 0.322 ENSMUST00000077730.5
Pik3c2b
phosphoinositide-3-kinase, class 2, beta polypeptide
chr13_-_21716143 0.314 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chr4_-_143212691 0.311 ENSMUST00000105778.1
ENSMUST00000134791.1
Prdm2

PR domain containing 2, with ZNF domain

chr11_-_90638062 0.308 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr17_-_34121944 0.296 ENSMUST00000151986.1
Brd2
bromodomain containing 2
chr17_+_55445550 0.282 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr10_+_127078886 0.273 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_-_129440800 0.272 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr6_-_42693087 0.272 ENSMUST00000121083.1
Fam115a
family with sequence similarity 115, member A
chr7_+_121034445 0.267 ENSMUST00000033163.6
Mettl9
methyltransferase like 9
chr13_-_21810190 0.265 ENSMUST00000110469.1
ENSMUST00000091749.2
Hist1h2bq

histone cluster 1, H2bq

chr7_-_23947237 0.261 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chr4_-_132212255 0.258 ENSMUST00000152796.1
Ythdf2
YTH domain family 2
chr2_-_119618455 0.256 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr7_+_128688480 0.253 ENSMUST00000118605.1
Inpp5f
inositol polyphosphate-5-phosphatase F

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 1.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.6 1.7 GO:0030070 insulin processing(GO:0030070)
0.5 2.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 1.5 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.5 2.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.4 2.2 GO:0019230 proprioception(GO:0019230)
0.3 9.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 1.0 GO:0061056 positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) sclerotome development(GO:0061056) kidney smooth muscle tissue development(GO:0072194)
0.3 0.9 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 0.9 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.3 0.9 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 0.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 1.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.3 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 2.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 2.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 3.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 3.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 2.0 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 0.6 GO:0070428 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.2 0.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 0.5 GO:1902022 L-lysine transport(GO:1902022)
0.2 0.5 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 1.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.0 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.6 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 0.4 GO:0046098 regulation of primitive erythrocyte differentiation(GO:0010725) guanine metabolic process(GO:0046098)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.1 GO:0001842 neural fold formation(GO:0001842)
0.1 0.7 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.6 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.3 GO:1903054 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334)
0.1 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.4 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 2.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.2 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 0.6 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.5 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 0.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.2 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 1.7 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.4 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 3.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.2 GO:0010288 response to lead ion(GO:0010288)
0.1 0.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.6 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.7 GO:0048096 nucleosome disassembly(GO:0006337) chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.9 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 1.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 6.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 2.2 GO:0070613 regulation of protein processing(GO:0070613)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.1 GO:0030317 sperm motility(GO:0030317)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.7 GO:0048675 axon extension(GO:0048675)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.0 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.0 GO:0051225 spindle assembly(GO:0051225)
0.0 0.4 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 1.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.3 1.4 GO:0008623 CHRAC(GO:0008623)
0.3 1.1 GO:0090537 CERF complex(GO:0090537)
0.3 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.2 2.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 3.1 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 7.0 GO:0005884 actin filament(GO:0005884)
0.0 4.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) actin filament bundle(GO:0032432) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.2 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.9 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 0.9 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 0.9 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.3 0.9 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 3.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 2.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 1.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 2.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.0 GO:0005113 patched binding(GO:0005113)
0.2 2.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.4 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.3 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.9 GO:0031432 titin binding(GO:0031432)
0.1 0.5 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.4 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 3.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 4.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 2.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.8 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.3 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 1.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 3.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 6.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 2.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.8 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.0 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.0 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.9 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 2.2 PID_IGF1_PATHWAY IGF1 pathway
0.1 1.7 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 1.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.9 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.2 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 2.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.5 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.7 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle