Motif ID: Sox15

Z-value: 0.472


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 127 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_119238794 1.638 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr3_-_8964037 1.250 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr17_+_55445550 1.240 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr6_-_23248264 1.022 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_+_17491216 0.988 ENSMUST00000080469.5
Met
met proto-oncogene
chr6_+_17463927 0.859 ENSMUST00000115442.1
Met
met proto-oncogene
chr6_+_17463749 0.813 ENSMUST00000115443.1
Met
met proto-oncogene
chr2_-_65567465 0.801 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 0.788 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_148265307 0.781 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148265202 0.780 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr3_+_31902666 0.741 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr18_+_33464163 0.723 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr6_+_17463826 0.715 ENSMUST00000140070.1
Met
met proto-oncogene
chr6_+_125552948 0.638 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr11_+_61653259 0.613 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr5_+_148265265 0.602 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr7_-_49636847 0.551 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chrX_+_109095359 0.520 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr10_-_30655859 0.515 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 1.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 1.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.3 GO:0050904 diapedesis(GO:0050904)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.6 GO:0031402 sodium ion binding(GO:0031402)
0.2 1.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 0.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism