Motif ID: Sox15

Z-value: 0.472


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_119238794 1.638 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr3_-_8964037 1.250 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr17_+_55445550 1.240 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr6_-_23248264 1.022 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_+_17491216 0.988 ENSMUST00000080469.5
Met
met proto-oncogene
chr6_+_17463927 0.859 ENSMUST00000115442.1
Met
met proto-oncogene
chr6_+_17463749 0.813 ENSMUST00000115443.1
Met
met proto-oncogene
chr2_-_65567465 0.801 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 0.788 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_148265307 0.781 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148265202 0.780 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr3_+_31902666 0.741 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr18_+_33464163 0.723 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr6_+_17463826 0.715 ENSMUST00000140070.1
Met
met proto-oncogene
chr6_+_125552948 0.638 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr11_+_61653259 0.613 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr5_+_148265265 0.602 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr7_-_49636847 0.551 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chrX_+_109095359 0.520 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr10_-_30655859 0.515 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr7_+_82174796 0.513 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr3_-_33082004 0.499 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr3_+_58415689 0.492 ENSMUST00000099090.2
Tsc22d2
TSC22 domain family, member 2
chr7_+_82175156 0.468 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr8_+_108714644 0.448 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr18_+_82554463 0.436 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr10_-_37138863 0.404 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr16_+_17146937 0.403 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc

YdjC homolog (bacterial)

chr11_+_88068242 0.397 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr10_+_29143996 0.376 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr6_+_86628174 0.370 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr5_+_66968416 0.358 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr5_+_19907502 0.357 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_+_71556874 0.355 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chrX_+_112604274 0.341 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr11_+_87760533 0.338 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chrX_-_59568068 0.326 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr4_-_70534904 0.320 ENSMUST00000107359.2
Megf9
multiple EGF-like-domains 9
chr3_+_37639985 0.308 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chr7_+_82867327 0.307 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr2_-_84425258 0.307 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr15_+_27466647 0.296 ENSMUST00000022875.6
Ank
progressive ankylosis
chr10_+_43579161 0.292 ENSMUST00000058714.8
Cd24a
CD24a antigen
chrX_+_112600526 0.291 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr11_-_106715251 0.280 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr14_-_48662740 0.267 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr1_-_153900198 0.249 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr2_+_18672384 0.246 ENSMUST00000171845.1
ENSMUST00000061158.4
Commd3

COMM domain containing 3

chr7_-_19861299 0.246 ENSMUST00000014830.7
Ceacam16
carcinoembryonic antigen-related cell adhesion molecule 16
chr10_+_53596936 0.242 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr6_+_86404219 0.241 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chr12_-_40445754 0.240 ENSMUST00000069692.8
ENSMUST00000069637.7
Zfp277

zinc finger protein 277

chr7_+_107370728 0.234 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr11_+_97663366 0.234 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_+_40446050 0.222 ENSMUST00000037488.6
Dock4
dedicator of cytokinesis 4
chr19_+_55741810 0.221 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr17_+_53479212 0.220 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family
chr17_+_52602700 0.212 ENSMUST00000039366.10
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr19_-_41848076 0.207 ENSMUST00000059231.2
Frat2
frequently rearranged in advanced T cell lymphomas 2
chr5_-_123721007 0.205 ENSMUST00000031376.7
Zcchc8
zinc finger, CCHC domain containing 8
chr10_+_116301374 0.198 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr14_-_79771305 0.195 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr2_+_4559742 0.195 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr1_+_19212054 0.186 ENSMUST00000064976.4
Tfap2b
transcription factor AP-2 beta
chr2_+_176236860 0.183 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr10_-_116473418 0.180 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr1_+_135146782 0.179 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chrX_-_57393020 0.177 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
Rbmx


RNA binding motif protein, X chromosome


chrX_-_57392962 0.174 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome
chr9_-_75597643 0.173 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr1_+_55406163 0.172 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr10_+_87859062 0.166 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr5_+_33983437 0.165 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr9_+_54863742 0.164 ENSMUST00000034843.7
Ireb2
iron responsive element binding protein 2
chr18_-_34624562 0.158 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr4_+_141242850 0.158 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr18_+_37307445 0.155 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr4_-_34882919 0.151 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr13_+_118714678 0.149 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr6_+_86404336 0.149 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr6_+_86404257 0.147 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr19_-_56822161 0.146 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr1_-_180330550 0.142 ENSMUST00000050581.3
Gm5069
predicted pseudogene 5069
chr14_-_70766598 0.140 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7

exportin 7

chr8_-_11312731 0.140 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr5_+_33983534 0.138 ENSMUST00000114382.1
Gm1673
predicted gene 1673
chr11_+_94044241 0.119 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr19_-_46962301 0.115 ENSMUST00000168536.1
Nt5c2
5'-nucleotidase, cytosolic II
chr6_-_121003099 0.115 ENSMUST00000098457.2
ENSMUST00000150503.1
Mical3

microtubule associated monooxygenase, calponin and LIM domain containing 3

chr4_-_129121889 0.110 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr6_+_17065129 0.110 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr17_+_47140942 0.108 ENSMUST00000077951.7
Trerf1
transcriptional regulating factor 1
chr5_-_92083455 0.105 ENSMUST00000169094.1
ENSMUST00000167918.1
G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr10_+_17796256 0.104 ENSMUST00000037964.6
Txlnb
taxilin beta
chr4_-_129742275 0.103 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr5_-_134946917 0.102 ENSMUST00000051401.2
Cldn4
claudin 4
chr6_+_65042575 0.101 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_-_6721890 0.097 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr12_+_37241633 0.085 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr18_+_4921662 0.081 ENSMUST00000143254.1
Svil
supervillin
chr14_+_79515618 0.080 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr11_-_77489666 0.080 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr11_+_94044194 0.076 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr11_+_94044331 0.073 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr14_+_79451791 0.073 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr10_-_29144194 0.071 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr5_-_92083667 0.070 ENSMUST00000113127.3
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr18_+_11633276 0.068 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr2_-_116067391 0.064 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrX_+_73757069 0.052 ENSMUST00000002079.6
Plxnb3
plexin B3
chr10_+_39612934 0.052 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr10_+_87859255 0.051 ENSMUST00000105300.2
Igf1
insulin-like growth factor 1
chr11_-_49712674 0.050 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6

CCR4-NOT transcription complex, subunit 6

chrX_+_143518671 0.046 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr10_+_57486354 0.037 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr6_-_132314757 0.030 ENSMUST00000048686.8
Prpmp5
proline-rich protein MP5
chr1_-_33814516 0.029 ENSMUST00000044455.5
ENSMUST00000115167.1
Zfp451

zinc finger protein 451

chr2_-_170406501 0.028 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr11_-_3863895 0.027 ENSMUST00000070552.7
Osbp2
oxysterol binding protein 2
chr13_+_21722057 0.026 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr15_-_58214882 0.024 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr9_-_103480328 0.024 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr1_+_158362261 0.020 ENSMUST00000046110.9
Astn1
astrotactin 1
chr2_-_60125651 0.008 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr15_+_99702278 0.003 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chrX_-_59567348 0.002 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr5_+_30711564 0.001 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.6 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.1 0.4 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 1.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.2 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:0050904 diapedesis(GO:0050904)
0.1 1.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.2 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.2 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0001756 somitogenesis(GO:0001756)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0033269 internode region of axon(GO:0033269)
0.1 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.6 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 2.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade