Motif ID: Sox2

Z-value: 3.567


Transcription factors associated with Sox2:

Gene SymbolEntrez IDGene Name
Sox2 ENSMUSG00000074637.4 Sox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox2mm10_v2_chr3_+_34649987_346500050.529.9e-04Click!


Activity profile for motif Sox2.

activity profile for motif Sox2


Sorted Z-values histogram for motif Sox2

Sorted Z-values for motif Sox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_45216671 37.560 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr7_-_115824699 32.719 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr7_-_49636847 31.148 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr1_-_138842429 29.940 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr7_-_116038734 28.666 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr9_+_118478851 24.097 ENSMUST00000150633.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_+_6734827 22.808 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr9_+_118478344 22.697 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr11_+_119022962 21.787 ENSMUST00000026662.7
Cbx2
chromobox 2
chr1_+_6487231 19.382 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr17_-_70851189 19.337 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr5_-_98030727 18.744 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr15_+_25622525 18.694 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr17_-_35703971 18.469 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr7_+_45215753 18.083 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr17_-_35704000 18.025 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr11_-_114795888 17.999 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr4_+_62965560 17.512 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr10_+_26229707 17.209 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr3_-_75956888 16.685 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr4_-_63403330 16.433 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr2_+_181763315 16.408 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr10_+_94036001 16.105 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr5_-_112228633 15.915 ENSMUST00000182699.1
ENSMUST00000182258.1
ENSMUST00000183036.1
Miat


myocardial infarction associated transcript (non-protein coding)


chr7_-_37772868 15.851 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr6_+_47244359 15.358 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr12_-_54986363 15.333 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr2_+_156840966 15.332 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr6_+_128375456 15.149 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr6_+_15185456 14.678 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr6_-_23248264 14.662 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_-_67037399 14.514 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr11_+_78301529 14.460 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr1_+_6730051 14.425 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr6_-_56362356 14.073 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr14_+_73237891 14.047 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr12_-_54986328 13.478 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr11_-_19018956 13.388 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr7_-_103853199 13.384 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr8_+_45507768 13.266 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr10_+_80150448 12.979 ENSMUST00000153477.1
Midn
midnolin
chr12_+_24708984 12.743 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr2_-_33942111 12.601 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr1_-_139377094 12.508 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr19_-_30175414 12.118 ENSMUST00000025778.7
Gldc
glycine decarboxylase
chr2_-_18048347 12.035 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr5_-_44099220 11.813 ENSMUST00000165909.1
Prom1
prominin 1
chr7_-_115846080 11.660 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr17_-_35704574 11.488 ENSMUST00000117301.1
ENSMUST00000134995.1
Ddr1

discoidin domain receptor family, member 1

chr3_+_131110350 11.213 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr17_-_35000848 10.892 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr7_+_127233044 10.740 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr2_-_84775420 10.649 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr6_+_83137089 10.648 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr17_+_72918298 10.646 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr11_-_96005872 10.584 ENSMUST00000013559.2
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr4_-_34882919 10.555 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr17_-_35697971 10.453 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr2_+_146221921 10.339 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr8_+_45628176 10.326 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr9_-_72111755 10.257 ENSMUST00000183492.1
ENSMUST00000184523.1
ENSMUST00000034755.6
Tcf12


transcription factor 12


chr1_+_6730135 10.212 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr2_-_51149100 10.194 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr4_+_128727585 10.182 ENSMUST00000106079.3
ENSMUST00000133439.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr11_-_19018714 9.949 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr2_-_151973387 9.939 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr4_+_136172367 9.598 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr9_-_75409951 9.580 ENSMUST00000049355.10
Mapk6
mitogen-activated protein kinase 6
chr18_+_82914632 9.562 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr5_-_124352233 9.562 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr17_+_43667389 9.542 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr4_-_135272798 9.439 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr3_+_102010138 9.427 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr12_+_24708241 9.395 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr2_-_151973840 9.376 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr14_+_31019183 9.370 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr13_+_51645232 9.290 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr9_-_72111651 9.274 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr5_-_112228900 9.225 ENSMUST00000182509.1
Miat
myocardial infarction associated transcript (non-protein coding)
chr18_-_46212595 9.221 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr4_-_32923455 9.217 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr2_-_160367057 9.170 ENSMUST00000099126.3
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr1_+_136131382 9.155 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr18_-_88927447 9.145 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr10_+_80151154 9.057 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr8_-_69184177 9.049 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr7_+_127233227 8.853 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr9_-_72111827 8.852 ENSMUST00000183404.1
ENSMUST00000184783.1
Tcf12

transcription factor 12

chr6_+_65042575 8.831 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr8_+_94977101 8.808 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr7_+_112679327 8.769 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr7_-_37769624 8.751 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr14_+_61138445 8.687 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr14_+_27039001 8.680 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr9_+_109095427 8.665 ENSMUST00000072093.6
Plxnb1
plexin B1
chr11_-_90638062 8.627 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr7_+_82867327 8.605 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr18_-_84086379 8.587 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr7_+_99466004 8.578 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr14_-_62456286 8.521 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chrX_-_16911774 8.490 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr2_+_124610573 8.485 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr12_-_101028983 8.397 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr2_-_153241402 8.389 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr15_-_91049823 8.314 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
Kif21a




kinesin family member 21A




chr6_-_38875965 8.283 ENSMUST00000160360.1
Hipk2
homeodomain interacting protein kinase 2
chr10_-_37138863 8.279 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr1_-_182019927 8.208 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr12_-_34528844 8.169 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr7_+_112679314 8.168 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr1_+_139454747 8.128 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr13_+_15463837 8.119 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr17_-_35701937 8.114 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr5_-_50058908 8.091 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr4_+_9269285 8.067 ENSMUST00000038841.7
Clvs1
clavesin 1
chr8_-_122699066 7.936 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr4_+_59626189 7.864 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr9_+_119402444 7.843 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr15_-_84855093 7.803 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr13_-_97747399 7.797 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr17_-_70853482 7.757 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr17_+_80944611 7.719 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr4_+_141010644 7.689 ENSMUST00000071977.8
Mfap2
microfibrillar-associated protein 2
chr17_+_43801823 7.680 ENSMUST00000044895.5
Rcan2
regulator of calcineurin 2
chr5_-_112228934 7.646 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr2_-_79456750 7.639 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr9_+_7764041 7.630 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr18_-_47368446 7.610 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr3_-_84040151 7.596 ENSMUST00000052342.7
D930015E06Rik
RIKEN cDNA D930015E06 gene
chrX_-_23285532 7.574 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr6_-_148944750 7.556 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr10_-_60831571 7.477 ENSMUST00000077925.5
Unc5b
unc-5 homolog B (C. elegans)
chr14_+_31019125 7.448 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr2_-_18048784 7.429 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr13_-_95618442 7.425 ENSMUST00000059193.5
F2r
coagulation factor II (thrombin) receptor
chr1_+_133246092 7.413 ENSMUST00000038295.8
ENSMUST00000105082.2
Plekha6

pleckstrin homology domain containing, family A member 6

chr4_-_110292719 7.411 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_+_3289168 7.399 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr1_-_139377041 7.369 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr8_+_34807287 7.349 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr13_-_97747373 7.337 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr12_+_76072016 7.281 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chrX_-_23365044 7.133 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr1_-_55226768 7.076 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr14_+_31019159 7.064 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr12_-_73113407 6.924 ENSMUST00000175693.1
Six4
sine oculis-related homeobox 4
chr8_+_127064022 6.921 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr10_+_79996479 6.895 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr5_+_75574916 6.892 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr16_+_84774123 6.884 ENSMUST00000114195.1
Jam2
junction adhesion molecule 2
chr4_-_97584605 6.879 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_+_90931196 6.847 ENSMUST00000071652.4
Mthfd2l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr7_-_120982260 6.778 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr3_-_108402589 6.684 ENSMUST00000147565.1
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr9_+_56041857 6.669 ENSMUST00000114276.2
Rcn2
reticulocalbin 2
chr9_-_58313189 6.664 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chr14_+_54431597 6.653 ENSMUST00000089688.4
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
chr5_+_124862674 6.652 ENSMUST00000111417.2
Zfp664
zinc finger protein 664
chr5_-_28210022 6.628 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr3_+_32708546 6.583 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr10_-_92162753 6.551 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr1_-_12991109 6.518 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr9_-_75409352 6.505 ENSMUST00000168937.1
Mapk6
mitogen-activated protein kinase 6
chr12_-_98737405 6.491 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr16_-_11066141 6.490 ENSMUST00000162323.1
Litaf
LPS-induced TN factor
chr18_+_35118880 6.467 ENSMUST00000042345.6
Ctnna1
catenin (cadherin associated protein), alpha 1
chr11_+_62077018 6.422 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr19_+_5740885 6.367 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr14_+_60378242 6.353 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr17_+_75005523 6.294 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr4_+_116221590 6.293 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr9_+_74976096 6.210 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr4_+_155839724 6.191 ENSMUST00000030947.3
Mxra8
matrix-remodelling associated 8
chr2_-_60125651 6.129 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_-_81442756 6.106 ENSMUST00000107262.1
ENSMUST00000102830.3
Mpdz

multiple PDZ domain protein

chr7_+_100493337 6.081 ENSMUST00000126534.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_-_56476462 6.063 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr8_+_70863127 6.057 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr14_+_14703025 6.046 ENSMUST00000057015.6
Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr4_-_155043143 6.041 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr2_+_126552407 6.028 ENSMUST00000061491.7
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr8_-_122678072 5.986 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr2_+_15055274 5.979 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr18_+_64340225 5.964 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr5_+_108694222 5.952 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr7_+_75643223 5.948 ENSMUST00000137959.1
Akap13
A kinase (PRKA) anchor protein 13
chr2_+_181767283 5.943 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr2_+_181767040 5.928 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr18_-_88894203 5.873 ENSMUST00000123826.1
Socs6
suppressor of cytokine signaling 6
chr14_-_48662740 5.873 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr4_-_110290884 5.823 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_+_107569112 5.818 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr18_-_47368830 5.816 ENSMUST00000019791.7
ENSMUST00000115449.2
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr2_+_68861564 5.806 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr10_-_80421847 5.803 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr1_-_14310198 5.802 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr17_-_25273155 5.776 ENSMUST00000173231.1
Ube2i
ubiquitin-conjugating enzyme E2I
chr18_+_34625009 5.767 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr6_+_53573364 5.766 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr4_-_20778527 5.749 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.6 46.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
8.1 8.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
8.0 87.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
8.0 23.9 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
6.0 29.9 GO:0035262 gonad morphogenesis(GO:0035262)
5.3 63.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
4.9 19.6 GO:0090235 regulation of metaphase plate congression(GO:0090235)
4.7 56.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
4.5 26.8 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
4.0 12.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.9 11.8 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
3.8 7.7 GO:0030220 platelet formation(GO:0030220)
3.8 61.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.7 11.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
3.6 17.9 GO:0015671 oxygen transport(GO:0015671)
3.6 39.2 GO:0060539 diaphragm development(GO:0060539)
3.5 10.6 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
3.4 10.3 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
3.3 76.2 GO:0048368 lateral mesoderm development(GO:0048368)
3.1 15.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
2.9 11.7 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
2.9 17.4 GO:0003383 apical constriction(GO:0003383)
2.9 8.6 GO:0060023 soft palate development(GO:0060023)
2.8 14.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
2.8 11.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
2.7 8.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
2.6 13.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.6 33.2 GO:0035881 amacrine cell differentiation(GO:0035881)
2.5 7.4 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
2.5 14.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.4 14.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.4 9.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.3 7.0 GO:0061113 pancreas morphogenesis(GO:0061113)
2.3 4.6 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
2.3 6.9 GO:1904347 intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
2.3 9.2 GO:0021603 cranial nerve formation(GO:0021603)
2.3 11.4 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
2.2 15.5 GO:0038092 nodal signaling pathway(GO:0038092)
2.2 8.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
2.2 8.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
2.2 6.5 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
2.1 4.3 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
2.1 10.6 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
2.1 2.1 GO:1904412 regulation of cardiac ventricle development(GO:1904412)
2.1 8.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
2.1 31.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
2.0 6.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
2.0 10.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
2.0 6.0 GO:0007403 glial cell fate determination(GO:0007403)
2.0 13.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
2.0 7.9 GO:0043973 histone H3-K4 acetylation(GO:0043973)
2.0 5.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.9 7.6 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
1.9 7.5 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.9 5.6 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
1.9 3.7 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.8 38.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
1.8 3.6 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
1.8 8.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.7 5.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.7 6.9 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
1.7 5.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.7 6.8 GO:0006547 histidine metabolic process(GO:0006547)
1.7 5.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.7 20.1 GO:0070933 histone H4 deacetylation(GO:0070933)
1.7 6.7 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
1.7 8.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.6 4.9 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
1.6 6.4 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
1.5 12.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.5 10.4 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
1.5 5.9 GO:0010288 response to lead ion(GO:0010288)
1.5 2.9 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
1.5 5.8 GO:0002326 B cell lineage commitment(GO:0002326)
1.4 8.6 GO:0072697 protein localization to cell cortex(GO:0072697)
1.4 11.3 GO:1990845 adaptive thermogenesis(GO:1990845)
1.4 11.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.4 5.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
1.4 8.3 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
1.4 5.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.3 4.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.3 24.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
1.3 10.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.3 3.8 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.3 22.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.3 5.1 GO:0070307 lens fiber cell development(GO:0070307)
1.3 5.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.2 3.7 GO:0007525 somatic muscle development(GO:0007525)
1.2 6.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
1.2 6.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
1.2 4.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.2 5.8 GO:0042117 monocyte activation(GO:0042117)
1.1 5.7 GO:0046208 spermine catabolic process(GO:0046208)
1.1 3.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.1 7.8 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
1.1 5.4 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.1 4.2 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.0 3.1 GO:0003162 atrioventricular node development(GO:0003162)
1.0 4.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
1.0 9.2 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
1.0 4.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.0 11.1 GO:0035988 chondrocyte proliferation(GO:0035988)
1.0 4.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.0 3.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
1.0 3.0 GO:0045658 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.0 5.9 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.0 4.0 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
1.0 3.0 GO:1903334 positive regulation of protein folding(GO:1903334)
1.0 9.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.0 9.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.9 7.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.9 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.9 3.7 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.9 2.8 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.9 1.8 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.9 4.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.9 1.8 GO:0035973 aggrephagy(GO:0035973)
0.9 8.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.9 6.1 GO:0033227 dsRNA transport(GO:0033227)
0.9 2.6 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.8 1.7 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.8 19.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.8 5.8 GO:0007296 vitellogenesis(GO:0007296)
0.8 2.4 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.8 3.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.8 2.4 GO:0034140 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146)
0.8 3.1 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.8 6.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.7 11.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.7 2.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.7 3.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.7 10.8 GO:0032092 positive regulation of protein binding(GO:0032092)
0.7 5.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.7 2.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.7 2.1 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.7 4.8 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.7 4.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.7 12.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.7 2.7 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.7 2.0 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.7 2.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.6 3.2 GO:0035063 nuclear speck organization(GO:0035063)
0.6 13.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.6 1.9 GO:1990859 cellular response to endothelin(GO:1990859)
0.6 3.2 GO:0061511 centriole elongation(GO:0061511)
0.6 14.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.6 4.3 GO:0050832 defense response to fungus(GO:0050832)
0.6 3.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.6 4.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.6 8.4 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.6 3.5 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.6 2.3 GO:0060017 parathyroid gland development(GO:0060017)
0.6 2.9 GO:0032493 detection of bacterium(GO:0016045) detection of molecule of bacterial origin(GO:0032490) response to bacterial lipoprotein(GO:0032493) detection of other organism(GO:0098543)
0.6 5.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.6 1.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.6 2.8 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.6 3.3 GO:0051013 microtubule severing(GO:0051013)
0.5 10.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.5 1.6 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 4.4 GO:0006265 DNA topological change(GO:0006265)
0.5 4.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.5 3.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 8.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.5 0.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.5 4.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.5 1.6 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.5 6.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.5 1.6 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.5 6.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.5 3.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.5 3.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 8.3 GO:0060009 Sertoli cell development(GO:0060009)
0.5 8.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 1.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.5 1.9 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.5 4.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.5 8.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.5 6.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.5 5.0 GO:0030238 male sex determination(GO:0030238)
0.4 4.0 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.4 2.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 7.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 2.1 GO:0072718 response to cisplatin(GO:0072718)
0.4 4.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 7.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 4.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 5.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 2.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.4 0.8 GO:0040010 positive regulation of growth rate(GO:0040010)
0.4 1.7 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 9.4 GO:0007035 vacuolar acidification(GO:0007035)
0.4 4.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 16.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 2.0 GO:0006868 glutamine transport(GO:0006868)
0.4 2.4 GO:0072553 terminal button organization(GO:0072553)
0.4 1.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.4 3.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 1.9 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.4 9.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.4 16.4 GO:0060612 adipose tissue development(GO:0060612)
0.4 8.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.4 3.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 1.9 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.4 2.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 3.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.4 1.9 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.4 1.9 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.4 9.2 GO:0035329 hippo signaling(GO:0035329)
0.4 2.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 10.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.4 1.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.3 1.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 9.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 2.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 3.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 2.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 3.3 GO:0015838 amino-acid betaine transport(GO:0015838)
0.3 0.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 3.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.3 GO:0021914 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.3 3.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 1.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 6.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 2.5 GO:1902414 protein localization to cell junction(GO:1902414)
0.3 8.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 0.9 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.3 3.4 GO:0006020 inositol metabolic process(GO:0006020)
0.3 0.6 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.3 17.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.3 7.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.3 3.0 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.3 2.6 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.3 1.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.3 0.8 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.3 3.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 2.5 GO:0000052 citrulline metabolic process(GO:0000052)
0.3 2.7 GO:1904738 vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752) positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.3 5.4 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.3 1.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 2.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 1.3 GO:0061073 anterior commissure morphogenesis(GO:0021960) ciliary body morphogenesis(GO:0061073)
0.3 8.1 GO:0010259 multicellular organism aging(GO:0010259)
0.3 8.4 GO:0031648 protein destabilization(GO:0031648)
0.3 5.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172) inhibitory postsynaptic potential(GO:0060080)
0.3 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 2.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 2.8 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.3 3.4 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.3 3.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 2.1 GO:0031639 plasminogen activation(GO:0031639)
0.3 1.5 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 1.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 1.3 GO:0033762 response to glucagon(GO:0033762)
0.3 1.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.2 3.0 GO:0045760 positive regulation of action potential(GO:0045760)
0.2 0.2 GO:0046104 thymidine metabolic process(GO:0046104)
0.2 0.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 4.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 0.7 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 0.9 GO:0046898 response to cycloheximide(GO:0046898)
0.2 6.0 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 2.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 3.6 GO:0033194 response to hydroperoxide(GO:0033194)
0.2 12.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.9 GO:0090282 trophectodermal cell proliferation(GO:0001834) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.2 1.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 2.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 1.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 1.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 2.4 GO:0006012 galactose metabolic process(GO:0006012)
0.2 4.1 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 4.6 GO:0016180 snRNA processing(GO:0016180)
0.2 28.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 1.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 1.3 GO:0072176 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.2 1.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 0.4 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.2 8.2 GO:1901998 toxin transport(GO:1901998)
0.2 4.3 GO:0042552 myelination(GO:0042552)
0.2 2.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 4.6 GO:0007340 acrosome reaction(GO:0007340)
0.2 0.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.2 1.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.4 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.2 0.4 GO:2000646 negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.2 2.6 GO:0008209 androgen metabolic process(GO:0008209)
0.2 1.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 1.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 1.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 0.4 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 0.7 GO:0006805 xenobiotic metabolic process(GO:0006805) cellular response to xenobiotic stimulus(GO:0071466)
0.2 1.4 GO:0035562 negative regulation of chromatin binding(GO:0035562) snRNA modification(GO:0040031)
0.2 2.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 1.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 1.4 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037)
0.2 0.9 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.2 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 1.5 GO:0045176 apical protein localization(GO:0045176)
0.2 13.9 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.2 2.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.5 GO:0016073 snRNA metabolic process(GO:0016073)
0.2 0.8 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 0.7 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164)
0.2 1.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.2 1.3 GO:0015074 DNA integration(GO:0015074)
0.2 4.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 1.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 2.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 2.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 2.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 4.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.1 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1 4.3 GO:0006739 NADP metabolic process(GO:0006739)
0.1 4.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 3.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 8.4 GO:0051289 protein homotetramerization(GO:0051289)
0.1 3.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 3.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1 3.0 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 1.3 GO:0002076 osteoblast development(GO:0002076)
0.1 6.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 1.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 6.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 8.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 6.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.5 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 2.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 1.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 1.4 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 1.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.4 GO:0051451 myoblast migration(GO:0051451)
0.1 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 2.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.1 GO:0021794 thalamus development(GO:0021794)
0.1 1.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 7.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.9 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.6 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178)
0.1 1.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 1.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 2.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 10.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 5.0 GO:0010950 positive regulation of endopeptidase activity(GO:0010950)
0.1 2.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 6.1 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.8 GO:0001967 suckling behavior(GO:0001967)
0.1 0.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 5.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 4.0 GO:0007601 visual perception(GO:0007601)
0.1 0.8 GO:0009148 CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
0.1 1.7 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 0.2 GO:0090190 positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 1.6 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 2.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.3 GO:0009299 mRNA transcription(GO:0009299)
0.1 1.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.1 GO:0001825 blastocyst formation(GO:0001825)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.0 GO:0009749 response to glucose(GO:0009749)
0.0 0.1 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 2.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 1.3 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.2 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.3 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 2.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 2.9 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.1 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.9 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 3.1 GO:0032259 methylation(GO:0032259)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0030850 prostate gland development(GO:0030850)
0.0 0.5 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
18.5 55.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
7.2 28.8 GO:0008623 CHRAC(GO:0008623)
5.6 16.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
4.4 22.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
3.9 11.8 GO:0071914 prominosome(GO:0071914)
2.8 8.3 GO:0042585 germinal vesicle(GO:0042585)
2.4 7.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
2.4 11.8 GO:0036449 microtubule minus-end(GO:0036449)
2.2 17.9 GO:0005833 hemoglobin complex(GO:0005833)
2.2 23.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
2.1 12.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
2.1 6.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.8 32.0 GO:0035102 PRC1 complex(GO:0035102)
1.8 23.0 GO:0043219 lateral loop(GO:0043219)
1.8 7.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
1.5 6.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.5 5.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.4 4.3 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
1.4 8.3 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
1.4 1.4 GO:0035101 FACT complex(GO:0035101)
1.3 10.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.2 7.4 GO:0031094 platelet dense tubular network(GO:0031094)
1.2 3.7 GO:0030905 retromer, tubulation complex(GO:0030905)
1.2 10.8 GO:0030478 actin cap(GO:0030478)
1.1 4.4 GO:0001651 dense fibrillar component(GO:0001651)
1.1 19.2 GO:0032156 septin cytoskeleton(GO:0032156)
1.1 1.1 GO:1902737 dendritic filopodium(GO:1902737)
1.0 3.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.0 6.0 GO:0005726 perichromatin fibrils(GO:0005726)
1.0 7.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.0 14.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.9 13.2 GO:0042788 polysomal ribosome(GO:0042788)
0.9 7.6 GO:0016580 Sin3 complex(GO:0016580)
0.9 3.7 GO:0008537 proteasome activator complex(GO:0008537)
0.9 3.7 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.9 9.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.9 8.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.8 5.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.8 8.7 GO:0016342 catenin complex(GO:0016342)
0.8 3.1 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.8 7.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.8 6.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.7 2.9 GO:0044307 dendritic branch(GO:0044307)
0.7 2.1 GO:1990047 spindle matrix(GO:1990047)
0.7 2.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.7 9.0 GO:0043596 nuclear replication fork(GO:0043596)
0.7 2.1 GO:0001652 granular component(GO:0001652)
0.7 4.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.7 11.1 GO:0000145 exocyst(GO:0000145)
0.6 3.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.6 1.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.6 1.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.6 82.0 GO:0032993 protein-DNA complex(GO:0032993)
0.6 13.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.6 239.0 GO:0005667 transcription factor complex(GO:0005667)
0.5 8.5 GO:0071564 npBAF complex(GO:0071564)
0.5 9.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 2.0 GO:0070822 Sin3-type complex(GO:0070822)
0.5 5.7 GO:0044294 dendritic growth cone(GO:0044294)
0.5 9.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 8.7 GO:0001891 phagocytic cup(GO:0001891)
0.4 4.0 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.4 32.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.4 27.6 GO:0016459 myosin complex(GO:0016459)
0.4 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 15.1 GO:0001772 immunological synapse(GO:0001772)
0.4 17.9 GO:0002102 podosome(GO:0002102)
0.4 4.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 24.4 GO:0005871 kinesin complex(GO:0005871)
0.4 1.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.4 2.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.4 4.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.4 5.8 GO:0036038 MKS complex(GO:0036038)
0.4 2.8 GO:0070652 HAUS complex(GO:0070652)
0.3 5.5 GO:0032039 integrator complex(GO:0032039)
0.3 3.3 GO:0070545 PeBoW complex(GO:0070545)
0.3 26.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 0.9 GO:0031251 PAN complex(GO:0031251)
0.3 21.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 3.7 GO:0070938 contractile ring(GO:0070938)
0.3 1.2 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 3.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 26.2 GO:0016363 nuclear matrix(GO:0016363)
0.3 5.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 3.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 5.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 5.6 GO:0031519 PcG protein complex(GO:0031519)
0.3 8.7 GO:1990391 DNA repair complex(GO:1990391)
0.3 23.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.3 5.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 7.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.2 8.2 GO:0072562 blood microparticle(GO:0072562)
0.2 0.9 GO:0043218 compact myelin(GO:0043218)
0.2 3.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 8.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 26.9 GO:0005923 bicellular tight junction(GO:0005923)
0.2 2.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 1.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 4.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 0.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 3.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 0.2 GO:0031430 M band(GO:0031430)
0.2 2.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 3.2 GO:0034399 nuclear periphery(GO:0034399)
0.2 8.8 GO:0005902 microvillus(GO:0005902)
0.2 3.0 GO:0005876 spindle microtubule(GO:0005876)
0.2 6.1 GO:0072686 mitotic spindle(GO:0072686)
0.2 7.9 GO:0005844 polysome(GO:0005844)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 17.6 GO:0000776 kinetochore(GO:0000776)
0.1 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.4 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.1 GO:0032420 stereocilium(GO:0032420)
0.1 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 3.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 5.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 9.1 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 5.1 GO:0042641 actomyosin(GO:0042641)
0.1 1.5 GO:0005771 multivesicular body(GO:0005771)
0.1 2.4 GO:0016592 mediator complex(GO:0016592)
0.1 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 0.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 6.8 GO:0005776 autophagosome(GO:0005776)
0.1 21.3 GO:0005815 microtubule organizing center(GO:0005815)
0.1 4.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 18.8 GO:0043235 receptor complex(GO:0043235)
0.1 5.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 3.4 GO:0030880 RNA polymerase complex(GO:0030880)
0.1 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 90.5 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 24.1 GO:0005730 nucleolus(GO:0005730)
0.0 132.5 GO:0005634 nucleus(GO:0005634)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 14.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 66.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
4.4 22.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.9 73.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
3.6 17.9 GO:0005344 oxygen transporter activity(GO:0005344)
3.0 9.1 GO:0005118 sevenless binding(GO:0005118)
2.9 8.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
2.9 17.2 GO:0070644 vitamin D response element binding(GO:0070644)
2.8 11.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
2.6 7.7 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
2.4 7.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.4 26.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.4 16.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.3 9.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.3 6.9 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.3 6.8 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
2.2 15.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.9 5.7 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.9 11.2 GO:0030284 estrogen receptor activity(GO:0030284)
1.8 7.1 GO:0005113 patched binding(GO:0005113)
1.8 12.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.7 5.1 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.7 13.4 GO:0046790 virion binding(GO:0046790)
1.6 13.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.6 6.4 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
1.6 6.3 GO:0050436 microfibril binding(GO:0050436)
1.6 29.7 GO:0070410 co-SMAD binding(GO:0070410)
1.5 4.6 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.5 6.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.5 7.6 GO:0070051 fibrinogen binding(GO:0070051)
1.5 28.4 GO:0035497 cAMP response element binding(GO:0035497)
1.5 11.7 GO:0050693 LBD domain binding(GO:0050693)
1.5 5.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
1.4 74.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
1.4 8.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
1.3 6.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
1.3 9.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.3 10.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.3 7.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 7.5 GO:0005042 netrin receptor activity(GO:0005042)
1.2 9.9 GO:0045294 alpha-catenin binding(GO:0045294)
1.2 3.6 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.1 22.5 GO:0030215 semaphorin receptor binding(GO:0030215)
1.1 4.4 GO:0097100 supercoiled DNA binding(GO:0097100)
1.1 9.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.1 9.6 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
1.1 4.2 GO:0043426 MRF binding(GO:0043426)
1.0 17.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.0 13.8 GO:0017154 semaphorin receptor activity(GO:0017154)
1.0 12.6 GO:0005522 profilin binding(GO:0005522)
1.0 4.8 GO:0008172 S-methyltransferase activity(GO:0008172)
1.0 12.4 GO:0030957 Tat protein binding(GO:0030957)
1.0 3.8 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.9 16.9 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.9 3.7 GO:1990460 leptin receptor binding(GO:1990460)
0.9 0.9 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.9 4.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.9 2.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.9 6.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.9 2.6 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.9 3.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.8 13.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.8 15.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 4.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.8 4.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.8 2.4 GO:0004335 galactokinase activity(GO:0004335)
0.8 3.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.8 6.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.8 4.6 GO:0001972 retinoic acid binding(GO:0001972)
0.8 4.5 GO:0097016 L27 domain binding(GO:0097016)
0.8 2.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.7 3.0 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.7 5.8 GO:0035198 miRNA binding(GO:0035198)
0.7 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.7 1.4 GO:0034046 poly(G) binding(GO:0034046)
0.7 7.8 GO:0048185 activin binding(GO:0048185)
0.7 2.1 GO:0071723 lipopeptide binding(GO:0071723)
0.7 2.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.7 114.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.7 4.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.7 2.6 GO:0038025 reelin receptor activity(GO:0038025)
0.7 2.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.6 1.9 GO:0008527 taste receptor activity(GO:0008527)
0.6 17.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 3.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.6 6.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.6 7.8 GO:0002162 dystroglycan binding(GO:0002162)
0.6 8.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.6 6.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.6 17.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.6 9.7 GO:0004707 MAP kinase activity(GO:0004707)
0.6 5.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.6 10.6 GO:0001848 complement binding(GO:0001848)
0.5 5.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 1.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.5 10.4 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.5 1.6 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.5 2.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.5 4.9 GO:0031996 thioesterase binding(GO:0031996)
0.5 1.9 GO:0033142 progesterone receptor binding(GO:0033142)
0.5 3.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.5 16.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 3.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.5 5.0 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.5 12.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 31.9 GO:0035064 methylated histone binding(GO:0035064)
0.4 16.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 4.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 8.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.4 13.3 GO:0045182 translation regulator activity(GO:0045182)
0.4 2.1 GO:0043559 insulin binding(GO:0043559)
0.4 1.7 GO:0004111 creatine kinase activity(GO:0004111)
0.4 3.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 2.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 1.7 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 7.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 3.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 2.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 14.4 GO:0017091 AU-rich element binding(GO:0017091)
0.4 44.9 GO:0003774 motor activity(GO:0003774)
0.4 1.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.4 5.2 GO:0070513 death domain binding(GO:0070513)
0.4 1.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 1.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.4 7.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 6.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 9.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 15.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.4 6.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 1.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 6.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 5.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 1.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 11.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 2.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 3.4 GO:0001727 lipid kinase activity(GO:0001727)
0.3 1.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3 1.9 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.3 0.6 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.3 3.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 1.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 0.9 GO:0019841 retinol binding(GO:0019841)
0.3 170.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.3 1.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 5.0 GO:0055103 ligase regulator activity(GO:0055103)
0.3 2.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 6.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 3.7 GO:0017166 vinculin binding(GO:0017166)
0.3 6.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 1.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.3 2.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 0.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.3 10.7 GO:0005109 frizzled binding(GO:0005109)
0.3 15.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.3 2.4 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3 7.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.3 3.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 1.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 0.8 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 4.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 5.9 GO:0030332 cyclin binding(GO:0030332)
0.2 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.2 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.2 5.0 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 6.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 12.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 0.6 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.2 6.6 GO:0042169 SH2 domain binding(GO:0042169)
0.2 3.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 8.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 2.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 3.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 7.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 2.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 4.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 4.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.2 3.4 GO:0004697 protein kinase C activity(GO:0004697)
0.2 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.2 1.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 174.0 GO:0003677 DNA binding(GO:0003677)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 7.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.8 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 3.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 3.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 5.3 GO:0051287 NAD binding(GO:0051287)
0.1 1.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.8 GO:0005112 Notch binding(GO:0005112)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 1.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 2.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 5.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.1 GO:0020037 heme binding(GO:0020037)
0.1 1.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 4.4 GO:0043130 ubiquitin binding(GO:0043130)
0.1 2.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.7 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0002054 nucleobase binding(GO:0002054)
0.0 3.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 3.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 2.2 GO:0002020 protease binding(GO:0002020)
0.0 3.7 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 2.4 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.0 9.6 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.9 53.2 PID_IL12_2PATHWAY IL12-mediated signaling events
0.9 8.7 PID_FGF_PATHWAY FGF signaling pathway
0.9 8.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.8 7.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.8 12.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.6 16.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.6 29.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.6 5.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.6 8.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.5 25.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.5 38.7 PID_CMYB_PATHWAY C-MYB transcription factor network
0.5 8.1 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.5 23.9 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.4 35.8 PID_E2F_PATHWAY E2F transcription factor network
0.4 11.7 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.4 4.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.4 15.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.4 15.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.4 11.1 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.4 11.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 3.2 PID_ALK2_PATHWAY ALK2 signaling events
0.4 8.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 2.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 12.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 8.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 21.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 9.6 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.3 16.3 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.3 11.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 5.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.3 7.5 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.3 1.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.3 23.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.3 0.9 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.3 11.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.3 5.7 PID_MYC_PATHWAY C-MYC pathway
0.3 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 2.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.3 1.3 PID_ALK1_PATHWAY ALK1 signaling events
0.3 12.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.3 6.2 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.3 11.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.3 10.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.3 5.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.2 3.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.2 7.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 3.3 PID_CD40_PATHWAY CD40/CD40L signaling
0.2 6.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 6.0 PID_ERBB4_PATHWAY ErbB4 signaling events
0.2 2.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 0.9 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.2 9.2 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.2 2.4 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.2 3.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.2 1.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 4.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 7.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 3.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 14.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.6 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.5 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.7 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 1.8 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 3.2 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 5.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.3 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.3 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 3.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID_IL1_PATHWAY IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 83.0 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.9 15.6 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.6 14.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
1.4 22.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.3 45.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
1.3 15.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
1.1 13.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.0 8.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.0 6.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 12.4 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.9 17.5 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.9 22.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.8 17.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.7 5.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.6 8.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 9.0 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.6 5.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 14.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.5 7.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.5 4.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 5.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5 16.5 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 16.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.4 6.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.4 7.5 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4 4.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 4.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 11.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.4 3.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.4 5.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 10.1 REACTOME_KINESINS Genes involved in Kinesins
0.4 1.9 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.4 3.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 5.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.3 6.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 6.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 2.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 7.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 8.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 11.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.3 9.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 12.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 7.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.3 4.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.3 30.3 REACTOME_MEIOSIS Genes involved in Meiosis
0.3 4.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 2.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 5.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 1.9 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 2.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 7.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 2.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 4.2 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 11.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 1.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 5.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.6 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 5.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.9 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 5.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.7 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 10.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 2.5 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 1.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 3.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.3 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.1 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.3 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 2.4 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 3.9 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.1 1.9 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 4.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 2.1 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 3.6 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.1 0.6 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 15.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 0.7 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 0.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 2.3 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 1.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 1.0 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.6 REACTOME_GLYCOSAMINOGLYCAN_METABOLISM Genes involved in Glycosaminoglycan metabolism
0.0 0.8 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)