Motif ID: Sox21

Z-value: 0.493


Transcription factors associated with Sox21:

Gene SymbolEntrez IDGene Name
Sox21 ENSMUSG00000061517.7 Sox21

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox21mm10_v2_chr14_-_118237016_1182370350.411.1e-02Click!


Activity profile for motif Sox21.

activity profile for motif Sox21


Sorted Z-values histogram for motif Sox21

Sorted Z-values for motif Sox21



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox21

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrM_-_14060 2.324 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr7_+_51621830 2.107 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr1_+_109993982 2.084 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr6_+_120666388 1.932 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr10_-_116972609 1.847 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr12_+_38783503 1.798 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr11_+_69045640 1.667 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr1_+_107511416 1.616 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr18_-_34007206 1.564 ENSMUST00000025234.5
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chrM_+_14138 1.441 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr2_-_72986716 1.229 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr4_+_116708467 1.110 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr9_-_73968901 1.061 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr18_-_15403680 0.880 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr7_-_25675047 0.857 ENSMUST00000108404.1
ENSMUST00000108405.1
ENSMUST00000079439.3
Tmem91


transmembrane protein 91


chr19_+_44493472 0.811 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr17_+_47737030 0.787 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr4_+_139923349 0.772 ENSMUST00000128563.1
Gm13028
predicted gene 13028
chr3_+_16183177 0.732 ENSMUST00000108345.2
ENSMUST00000108346.2
Ythdf3

YTH domain family 3

chr8_-_57652993 0.710 ENSMUST00000110316.2
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chrM_+_11734 0.685 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_+_73312601 0.655 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3

secernin 3

chr1_-_150465563 0.650 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr1_+_171113918 0.611 ENSMUST00000129651.1
ENSMUST00000151340.1
1700009P17Rik

RIKEN cDNA 1700009P17 gene

chr9_-_79793507 0.593 ENSMUST00000120690.1
Tmem30a
transmembrane protein 30A
chr9_-_79793378 0.574 ENSMUST00000034878.5
Tmem30a
transmembrane protein 30A
chr3_-_33082004 0.543 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr1_-_24612700 0.516 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrX_-_75578188 0.512 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr13_-_85127514 0.469 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr1_-_172027269 0.445 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chrM_+_10167 0.430 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr10_+_42860776 0.425 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr17_-_6655939 0.413 ENSMUST00000179554.1
Dynlt1f
dynein light chain Tctex-type 1F
chr8_-_111393810 0.406 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr4_-_25281752 0.402 ENSMUST00000038705.7
Ufl1
UFM1 specific ligase 1
chr6_-_86733268 0.396 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr7_+_123123870 0.386 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr2_-_73312701 0.385 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr18_-_67549173 0.372 ENSMUST00000115050.1
Spire1
spire homolog 1 (Drosophila)
chr17_-_6317474 0.367 ENSMUST00000169415.1
Dynlt1a
dynein light chain Tctex-type 1A
chr2_-_170131156 0.360 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr11_+_69964758 0.359 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
Cldn7


claudin 7


chr4_-_25281801 0.353 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr4_+_116557658 0.336 ENSMUST00000030460.8
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr5_+_144255223 0.333 ENSMUST00000056578.6
Bri3
brain protein I3
chr1_-_125913101 0.333 ENSMUST00000161361.1
Lypd1
Ly6/Plaur domain containing 1
chr16_-_59632520 0.332 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr17_-_70998010 0.311 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_+_6430112 0.305 ENSMUST00000179569.1
Dynlt1b
dynein light chain Tctex-type 1B
chr15_+_6708372 0.299 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr13_+_97137937 0.297 ENSMUST00000042084.6
ENSMUST00000160139.1
ENSMUST00000161639.1
ENSMUST00000161913.1
ENSMUST00000161825.1
ENSMUST00000161929.1
ENSMUST00000022170.7
Gfm2






G elongation factor, mitochondrial 2






chr2_-_147186389 0.289 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr6_+_57580992 0.281 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr4_-_131967824 0.276 ENSMUST00000146443.1
ENSMUST00000135579.1
Epb4.1

erythrocyte protein band 4.1

chr2_-_155582656 0.272 ENSMUST00000126322.1
Gss
glutathione synthetase
chr7_+_141195047 0.268 ENSMUST00000047093.4
Lrrc56
leucine rich repeat containing 56
chr8_+_104961713 0.263 ENSMUST00000043183.7
Ces2g
carboxylesterase 2G
chr1_+_74362108 0.260 ENSMUST00000097697.1
Gm216
predicted gene 216
chr17_+_6601671 0.248 ENSMUST00000092966.4
Dynlt1c
dynein light chain Tctex-type 1C
chr1_-_135167606 0.243 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr18_+_4993795 0.240 ENSMUST00000153016.1
Svil
supervillin
chr4_+_146654927 0.239 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr3_+_32436376 0.238 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_-_135585314 0.224 ENSMUST00000040599.8
ENSMUST00000067414.6
Nav1

neuron navigator 1

chr3_-_100685431 0.220 ENSMUST00000008907.7
Man1a2
mannosidase, alpha, class 1A, member 2
chr13_-_55100248 0.218 ENSMUST00000026997.5
ENSMUST00000127195.1
ENSMUST00000099496.3
Uimc1


ubiquitin interaction motif containing 1


chr13_-_19619820 0.213 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr10_-_18023229 0.207 ENSMUST00000020002.7
Abracl
ABRA C-terminal like
chr1_+_62703667 0.205 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
Nrp2



neuropilin 2



chr4_-_98383232 0.193 ENSMUST00000143116.1
ENSMUST00000030292.5
ENSMUST00000102793.4
Tm2d1


TM2 domain containing 1


chr11_+_114675431 0.187 ENSMUST00000045779.5
Ttyh2
tweety homolog 2 (Drosophila)
chr11_+_35769462 0.183 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr10_+_42860648 0.182 ENSMUST00000105495.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr8_+_33517306 0.176 ENSMUST00000124496.1
Tex15
testis expressed gene 15
chr2_+_70508813 0.171 ENSMUST00000100041.2
Erich2
glutamate rich 2
chr8_-_18741542 0.166 ENSMUST00000033846.6
Angpt2
angiopoietin 2
chr9_+_104063678 0.165 ENSMUST00000047799.5
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr9_-_104063049 0.165 ENSMUST00000035166.5
Uba5
ubiquitin-like modifier activating enzyme 5
chrX_+_166170449 0.151 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
Gemin8



gem (nuclear organelle) associated protein 8



chr16_+_32247221 0.143 ENSMUST00000178573.1
ENSMUST00000023474.3
Wdr53

WD repeat domain 53

chrX_-_111536325 0.135 ENSMUST00000156639.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr1_-_172027251 0.135 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr10_-_13388753 0.135 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr17_-_26099257 0.121 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr5_+_23787691 0.114 ENSMUST00000030852.6
ENSMUST00000120869.1
ENSMUST00000117783.1
ENSMUST00000115113.2
Rint1



RAD50 interactor 1



chr19_-_24961545 0.105 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr2_-_170194033 0.099 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr12_-_40134175 0.089 ENSMUST00000078481.7
ENSMUST00000002640.5
Scin

scinderin

chr10_-_62507737 0.083 ENSMUST00000020271.6
Srgn
serglycin
chr12_+_100110148 0.081 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr11_+_88047302 0.081 ENSMUST00000139129.2
Srsf1
serine/arginine-rich splicing factor 1
chr8_-_45410539 0.069 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr14_+_64588112 0.063 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr4_+_116558056 0.059 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr6_-_56797637 0.038 ENSMUST00000114323.1
Kbtbd2
kelch repeat and BTB (POZ) domain containing 2
chr5_+_143403819 0.035 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_-_6935081 0.031 ENSMUST00000100426.2
Gm10855
predicted gene 10855
chr9_+_104063376 0.028 ENSMUST00000120854.1
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr2_+_173737492 0.024 ENSMUST00000067530.4
Vapb
vesicle-associated membrane protein, associated protein B and C
chr19_+_7557473 0.022 ENSMUST00000141887.1
ENSMUST00000136756.1
Pla2g16

phospholipase A2, group XVI

chr10_+_127849917 0.015 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chr7_-_144678851 0.013 ENSMUST00000131731.1
Ano1
anoctamin 1, calcium activated chloride channel
chr2_+_174450678 0.012 ENSMUST00000016399.5
Tubb1
tubulin, beta 1 class VI
chr7_+_29953621 0.011 ENSMUST00000077142.2
C230062I16Rik
RIKEN cDNA C230062I16 gene
chr17_+_35342242 0.007 ENSMUST00000074806.5
H2-Q2
histocompatibility 2, Q region locus 2
chr19_+_7557452 0.004 ENSMUST00000025925.4
ENSMUST00000136465.1
Pla2g16

phospholipase A2, group XVI

chr18_-_77565050 0.002 ENSMUST00000182153.1
ENSMUST00000182146.1
ENSMUST00000026494.7
ENSMUST00000182024.1
Rnf165



ring finger protein 165




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 1.4 GO:0033762 response to glucagon(GO:0033762)
0.3 0.8 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.2 2.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.9 GO:0001842 neural fold formation(GO:0001842)
0.2 0.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.9 GO:0070295 renal water absorption(GO:0070295)
0.2 1.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.6 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2 0.9 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.4 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 1.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.5 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.1 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.4 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0045349 regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0090537 CERF complex(GO:0090537)
0.3 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.1 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0060187 cell pole(GO:0060187)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 2.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 3.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.3 1.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 0.8 GO:0071568 UFM1 transferase activity(GO:0071568)
0.2 1.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.9 GO:0015288 porin activity(GO:0015288)
0.1 3.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 2.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.7 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation