Motif ID: Sox30

Z-value: 0.291


Transcription factors associated with Sox30:

Gene SymbolEntrez IDGene Name
Sox30 ENSMUSG00000040489.5 Sox30



Activity profile for motif Sox30.

activity profile for motif Sox30


Sorted Z-values histogram for motif Sox30

Sorted Z-values for motif Sox30



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 2.548 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_+_135729147 1.274 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr5_+_92809372 0.789 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr18_-_88927447 0.782 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr3_+_34649987 0.722 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr10_-_62792243 0.633 ENSMUST00000020268.5
 Ccar1
cell division cycle and apoptosis regulator 1
chr12_-_99883429 0.606 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr9_-_72111651 0.602 ENSMUST00000185117.1
 Tcf12
transcription factor 12
chr9_+_7764041 0.555 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr6_-_12749193 0.466 ENSMUST00000046121.6
ENSMUST00000172356.1
 Thsd7a

thrombospondin, type I, domain containing 7A

chr13_-_97747373 0.454 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr10_+_17796256 0.452 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr6_-_3494587 0.435 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr18_-_62756275 0.430 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr9_-_103480328 0.423 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr1_+_10056922 0.322 ENSMUST00000149214.1
 Cspp1
centrosome and spindle pole associated protein 1
chr1_+_37997975 0.318 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr13_-_97747399 0.272 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_48585135 0.265 ENSMUST00000030032.6
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_+_137993445 0.265 ENSMUST00000105831.2
ENSMUST00000084214.5
 Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr7_+_127800604 0.257 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr10_-_53647080 0.236 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr2_-_181599128 0.234 ENSMUST00000060173.8
 Samd10
sterile alpha motif domain containing 10
chr11_+_21091291 0.201 ENSMUST00000093290.5
 Peli1
pellino 1
chrX_-_134161928 0.188 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr4_+_48585193 0.179 ENSMUST00000107703.1
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr14_+_116925379 0.165 ENSMUST00000088483.3
 Gpc6
glypican 6
chr2_-_65567465 0.157 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr7_+_90426312 0.156 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89
chr17_-_79355082 0.154 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr2_-_65567505 0.154 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr13_-_56135629 0.147 ENSMUST00000016081.6
ENSMUST00000045788.7
 H2afy

H2A histone family, member Y

chr9_+_74976096 0.136 ENSMUST00000081746.5
 Fam214a
family with sequence similarity 214, member A
chr4_+_109343029 0.128 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chr11_+_3983704 0.124 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_51261719 0.123 ENSMUST00000130641.1
 Clk4
CDC like kinase 4
chr11_+_3983636 0.121 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr12_+_8674129 0.109 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr4_+_137993016 0.107 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
 Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr4_+_83417715 0.101 ENSMUST00000030206.3
ENSMUST00000071544.4
 Snapc3

small nuclear RNA activating complex, polypeptide 3

chr12_+_8674224 0.101 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr19_-_56822161 0.091 ENSMUST00000118592.1
 A630007B06Rik
RIKEN cDNA A630007B06 gene
chr2_-_119787504 0.074 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
 Rpap1


RNA polymerase II associated protein 1


chr2_-_101883010 0.067 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr10_+_90829538 0.064 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_-_24836165 0.062 ENSMUST00000020169.7
 Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr19_+_44293676 0.033 ENSMUST00000026221.5
 Scd2
stearoyl-Coenzyme A desaturase 2
chr6_-_132314757 0.029 ENSMUST00000048686.8
 Prpmp5
proline-rich protein MP5
chr13_-_102958084 0.017 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chr6_-_122340200 0.002 ENSMUST00000159384.1
 Phc1
polyhomeotic-like 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.1 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.1 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.8 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex