Motif ID: Sox5_Sry

Z-value: 1.839

Transcription factors associated with Sox5_Sry:

Gene SymbolEntrez IDGene Name
Sox5 ENSMUSG00000041540.10 Sox5
Sry ENSMUSG00000069036.3 Sry

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_143947092_1439471110.334.3e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Sox5_Sry

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_115824699 20.458 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr3_+_127633134 13.897 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr17_-_70849644 10.925 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr18_-_84086379 9.946 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr1_+_6730051 9.847 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr2_-_60125651 9.828 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_-_97584612 9.618 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 9.312 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_+_109978004 9.182 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr13_-_56252163 8.594 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr6_+_15185456 8.419 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr10_-_130280218 8.168 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr18_-_62756275 8.011 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr2_+_102658640 7.843 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_+_94044111 7.040 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr6_+_128375456 7.009 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr1_+_6730135 6.704 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr11_-_50292302 6.486 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr10_-_128704978 6.423 ENSMUST00000026416.7
ENSMUST00000026415.7
Cdk2

cyclin-dependent kinase 2

chr4_-_82505707 6.309 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr7_-_37770757 6.299 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr4_-_110287479 6.286 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr10_-_92165159 6.193 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr2_+_124610573 5.698 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chrX_-_23285532 5.646 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr1_-_138842429 5.541 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr16_-_16560046 5.536 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr4_-_82505274 5.486 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr11_+_44617310 5.425 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr7_-_37773555 5.075 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr9_-_72111172 4.924 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr10_+_88091070 4.845 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr12_-_34528844 4.842 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr2_+_25180737 4.714 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr2_+_154436437 4.642 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr15_+_25622525 4.616 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr6_-_71632651 4.595 ENSMUST00000167220.1
Kdm3a
lysine (K)-specific demethylase 3A
chr2_-_118549668 4.495 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chr15_+_25773985 4.394 ENSMUST00000125667.1
Myo10
myosin X
chr6_-_71632897 4.384 ENSMUST00000065509.4
Kdm3a
lysine (K)-specific demethylase 3A
chr10_-_92164666 4.356 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr15_-_10713537 4.257 ENSMUST00000090339.3
Rai14
retinoic acid induced 14
chr11_-_115813621 4.255 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr4_-_3938354 4.144 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr2_-_84775388 4.054 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_+_80186835 4.019 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr2_-_84775420 3.991 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_169405435 3.863 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr11_+_94044194 3.856 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr9_-_72111651 3.844 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr16_-_36784784 3.743 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr4_-_82705735 3.628 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr3_+_131110350 3.608 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr3_+_34649987 3.572 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr4_-_82505749 3.561 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr1_-_119837613 3.553 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr16_-_44558879 3.533 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr1_-_14310198 3.523 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr6_+_15196949 3.523 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr6_-_93913678 3.523 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr16_-_78576649 3.354 ENSMUST00000114220.1
ENSMUST00000114219.1
ENSMUST00000114218.1
D16Ertd472e


DNA segment, Chr 16, ERATO Doi 472, expressed


chr11_+_94044331 3.300 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr16_-_44558864 3.300 ENSMUST00000023370.4
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr2_+_153031852 3.208 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr2_+_181763315 3.197 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chrX_-_145505175 3.194 ENSMUST00000143610.1
Amot
angiomotin
chr6_+_34709610 3.188 ENSMUST00000031775.6
Cald1
caldesmon 1
chr11_+_94044241 3.172 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr9_+_70207342 3.152 ENSMUST00000034745.7
Myo1e
myosin IE
chr8_+_120488416 3.147 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr4_-_110290884 3.126 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_-_97747399 3.106 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr6_+_34709442 3.062 ENSMUST00000115021.1
Cald1
caldesmon 1
chr1_+_34005872 3.020 ENSMUST00000182296.1
Dst
dystonin
chr6_-_144209558 2.986 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chrX_-_145505136 2.914 ENSMUST00000112835.1
Amot
angiomotin
chr4_+_97777606 2.851 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr13_-_97747373 2.838 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr12_-_99393010 2.795 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr10_-_45470201 2.783 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr6_-_113934679 2.765 ENSMUST00000101044.2
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr1_+_55406163 2.739 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr2_+_32535315 2.727 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr12_-_31950535 2.638 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr18_+_11633276 2.630 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr19_-_4334001 2.596 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr9_+_96196246 2.589 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr6_-_120364344 2.565 ENSMUST00000146667.1
Ccdc77
coiled-coil domain containing 77
chr4_-_45489794 2.519 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr19_+_53310495 2.466 ENSMUST00000003870.7
Mxi1
Max interacting protein 1
chr16_-_4213404 2.404 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr1_-_165934900 2.392 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr10_+_17723220 2.362 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_-_119836999 2.360 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr10_+_18407658 2.326 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr2_+_92185438 2.315 ENSMUST00000128781.2
Phf21a
PHD finger protein 21A
chr17_-_70853482 2.271 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr4_+_108460000 2.258 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr6_+_120364094 2.245 ENSMUST00000100996.3
ENSMUST00000005108.7
Kdm5a

lysine (K)-specific demethylase 5A

chr4_+_97777780 2.218 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr16_+_42907563 2.088 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chrX_+_141475385 2.074 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr19_+_55894508 2.072 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr4_-_91376490 2.072 ENSMUST00000107124.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_168601620 2.061 ENSMUST00000171689.1
ENSMUST00000137451.1
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr5_+_124862674 2.033 ENSMUST00000111417.2
Zfp664
zinc finger protein 664
chr4_+_11579647 2.013 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr1_-_64121389 1.984 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr16_-_16560201 1.974 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr10_+_53596936 1.971 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_+_15287259 1.965 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr4_-_24430838 1.952 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr9_+_52047150 1.944 ENSMUST00000163153.1
Rdx
radixin
chr2_+_92185467 1.884 ENSMUST00000111291.2
Phf21a
PHD finger protein 21A
chr13_+_44731281 1.845 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr1_-_119837338 1.842 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr7_+_75455534 1.835 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr10_+_69534208 1.822 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr4_+_144893077 1.794 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr9_-_82975475 1.786 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr4_-_133967235 1.764 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr9_-_50727921 1.763 ENSMUST00000118707.1
ENSMUST00000034566.8
Dixdc1

DIX domain containing 1

chr7_+_27499315 1.753 ENSMUST00000098644.2
ENSMUST00000108355.1
Prx

periaxin

chr10_+_69534039 1.737 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr2_-_121171107 1.727 ENSMUST00000163766.1
ENSMUST00000146243.1
Zscan29

zinc finger SCAN domains 29

chr6_+_134035691 1.717 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr18_-_3337539 1.705 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr1_+_87404916 1.704 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr17_-_51810866 1.686 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr2_+_146221921 1.685 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr4_+_144893127 1.664 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr19_+_40831296 1.662 ENSMUST00000119316.1
Ccnj
cyclin J
chr4_-_91376433 1.657 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr12_+_51348265 1.650 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr12_+_51348370 1.645 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr12_+_52516077 1.617 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr5_+_17574268 1.615 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr9_+_118040576 1.612 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chrX_+_42149534 1.585 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr9_+_7764041 1.572 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr4_+_137993016 1.571 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr9_+_122923050 1.571 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105

zinc finger protein 105

chr2_-_181578906 1.570 ENSMUST00000136875.1
Uckl1
uridine-cytidine kinase 1-like 1
chr1_-_97761538 1.562 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr9_+_74976096 1.557 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr2_-_64097994 1.539 ENSMUST00000131615.2
Fign
fidgetin
chrX_+_42151002 1.529 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr2_+_18055203 1.525 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_160906372 1.523 ENSMUST00000161609.1
Rc3h1
RING CCCH (C3H) domains 1
chr10_+_69533803 1.500 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr13_+_44840686 1.492 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr11_-_58330319 1.458 ENSMUST00000065533.2
Gm9900
predicted gene 9900
chrX_+_42149288 1.429 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr9_+_118040509 1.421 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chr1_+_133045984 1.407 ENSMUST00000077730.5
Pik3c2b
phosphoinositide-3-kinase, class 2, beta polypeptide
chr18_+_69344503 1.404 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr1_-_181211437 1.397 ENSMUST00000162963.1
ENSMUST00000162819.1
Wdr26

WD repeat domain 26

chr10_-_30842765 1.395 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr13_-_67360509 1.390 ENSMUST00000081582.6
ENSMUST00000185002.1
Zfp953
ZFP953
zinc finger protein 953
Protein Zfp953
chr19_+_40831248 1.387 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chr6_-_3494587 1.386 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr2_-_116067391 1.382 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_12991109 1.373 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chrX_-_12128350 1.366 ENSMUST00000123004.1
Bcor
BCL6 interacting corepressor
chr12_+_71136848 1.366 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr14_+_116925379 1.362 ENSMUST00000088483.3
Gpc6
glypican 6
chr7_-_119895446 1.357 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr3_+_55782500 1.354 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr9_-_103480328 1.348 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr9_-_64022043 1.347 ENSMUST00000041029.5
Smad6
SMAD family member 6
chr4_-_135873546 1.328 ENSMUST00000142585.1
Pnrc2
proline-rich nuclear receptor coactivator 2
chr13_-_40733768 1.315 ENSMUST00000110193.2
Tfap2a
transcription factor AP-2, alpha
chr9_-_50728067 1.295 ENSMUST00000117646.1
Dixdc1
DIX domain containing 1
chr4_-_83486453 1.293 ENSMUST00000107214.2
ENSMUST00000107215.2
ENSMUST00000030207.8
Psip1


PC4 and SFRS1 interacting protein 1


chr10_+_69706326 1.257 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr7_+_90426312 1.253 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr17_+_4994904 1.251 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr6_-_114921778 1.247 ENSMUST00000032459.7
Vgll4
vestigial like 4 (Drosophila)
chr9_+_118040475 1.246 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr4_-_83486178 1.233 ENSMUST00000130626.1
Psip1
PC4 and SFRS1 interacting protein 1
chr11_+_58330712 1.220 ENSMUST00000116376.2
Sh3bp5l
SH3 binding domain protein 5 like
chr19_-_56822161 1.205 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr6_+_65042575 1.195 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_52497244 1.185 ENSMUST00000114578.4
Vma21-ps
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae), pseudogene
chr1_+_187997835 1.182 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr4_-_135873801 1.181 ENSMUST00000030436.5
Pnrc2
proline-rich nuclear receptor coactivator 2
chr19_+_53329413 1.159 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr4_+_17853451 1.131 ENSMUST00000029881.3
Mmp16
matrix metallopeptidase 16
chr18_+_35599219 1.104 ENSMUST00000115734.1
Paip2
polyadenylate-binding protein-interacting protein 2
chr4_+_108459389 1.084 ENSMUST00000106673.1
ENSMUST00000043368.5
Zcchc11

zinc finger, CCHC domain containing 11

chr1_+_187997821 1.080 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr15_+_34082664 1.052 ENSMUST00000022865.9
Mtdh
metadherin
chr9_-_114844090 1.052 ENSMUST00000047013.3
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr5_-_131616599 1.051 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr11_-_100850724 1.044 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr8_-_67818284 1.042 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr1_-_64121456 1.034 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr15_-_50882806 1.032 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr4_+_137993445 1.023 ENSMUST00000105831.2
ENSMUST00000084214.5
Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chrX_-_12128386 1.005 ENSMUST00000145872.1
Bcor
BCL6 interacting corepressor

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 19.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
3.3 9.9 GO:0060023 soft palate development(GO:0060023)
3.0 9.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
2.7 8.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.5 9.9 GO:0021603 cranial nerve formation(GO:0021603)
2.2 17.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
2.2 6.5 GO:0003162 atrioventricular node development(GO:0003162)
2.1 23.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.8 28.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.6 4.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.5 6.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.3 6.4 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
1.3 15.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.2 3.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.1 7.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.1 5.5 GO:0035262 gonad morphogenesis(GO:0035262)
1.1 4.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.9 6.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.8 7.5 GO:0030035 microspike assembly(GO:0030035)
0.8 8.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.7 3.7 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.7 3.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 8.4 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.7 6.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 3.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.6 2.4 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.6 2.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.6 2.4 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.6 1.7 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.5 6.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 2.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.5 2.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.5 6.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.5 4.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.5 5.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.5 3.0 GO:0048840 otolith development(GO:0048840)
0.5 4.5 GO:0048102 autophagic cell death(GO:0048102)
0.5 1.4 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.5 1.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.5 1.4 GO:0003195 tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.4 7.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 3.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.4 4.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.4 1.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.4 2.7 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.4 2.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.4 5.1 GO:0072189 ureter development(GO:0072189)
0.4 0.7 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.4 1.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.0 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.3 1.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 2.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.3 2.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 2.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 1.6 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3 2.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 1.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3 1.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 7.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 2.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.3 2.3 GO:0097475 motor neuron migration(GO:0097475)
0.3 3.2 GO:0060539 diaphragm development(GO:0060539)
0.3 3.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.9 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.3 1.4 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.3 1.6 GO:0060666 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 0.8 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.3 1.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 1.7 GO:0007296 vitellogenesis(GO:0007296)
0.2 2.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.5 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 3.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 2.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.6 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.2 2.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 2.1 GO:0060736 prostate gland growth(GO:0060736)
0.2 1.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.4 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.7 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 0.4 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.2 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 4.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 0.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 3.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.0 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.4 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 12.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488) anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0097274 ductus arteriosus closure(GO:0097070) urea homeostasis(GO:0097274)
0.1 2.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.4 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 4.0 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.5 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.3 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.8 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.8 GO:0061368 parturition(GO:0007567) maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 5.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 6.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 2.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0007144 female meiosis I(GO:0007144)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.4 GO:0010225 response to UV-C(GO:0010225)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.6 GO:0001967 suckling behavior(GO:0001967)
0.1 0.1 GO:0060160 gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883) negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.7 GO:0042711 maternal behavior(GO:0042711)
0.1 8.0 GO:0048469 cell maturation(GO:0048469)
0.1 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 2.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.0 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.4 GO:0009301 snRNA transcription(GO:0009301)
0.0 1.8 GO:0051591 response to cAMP(GO:0051591)
0.0 3.3 GO:0001824 blastocyst development(GO:0001824)
0.0 5.3 GO:0000910 cytokinesis(GO:0000910)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.6 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.7 GO:0007030 Golgi organization(GO:0007030)
0.0 3.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.8 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.9 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.7 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.3 6.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.9 19.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.8 3.0 GO:0031673 H zone(GO:0031673)
0.7 6.2 GO:0030478 actin cap(GO:0030478)
0.6 3.2 GO:0032437 cuticular plate(GO:0032437)
0.6 9.4 GO:0042788 polysomal ribosome(GO:0042788)
0.6 6.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.4 1.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.4 8.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 2.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 2.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 2.2 GO:0097165 nuclear stress granule(GO:0097165)
0.3 0.8 GO:0034657 GID complex(GO:0034657)
0.2 7.8 GO:0030673 axolemma(GO:0030673)
0.2 13.3 GO:0016459 myosin complex(GO:0016459)
0.2 2.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 6.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.0 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.4 GO:0051286 cell tip(GO:0051286)
0.1 21.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 22.1 GO:0032993 protein-DNA complex(GO:0032993)
0.1 6.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.5 GO:1990391 DNA repair complex(GO:1990391)
0.1 2.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 7.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.4 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 8.6 GO:0072562 blood microparticle(GO:0072562)
0.1 1.2 GO:0043596 nuclear replication fork(GO:0043596)
0.1 9.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 4.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 2.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 10.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 16.4 GO:0000785 chromatin(GO:0000785)
0.0 4.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 6.7 GO:0030027 lamellipodium(GO:0030027)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 2.5 GO:0043679 axon terminus(GO:0043679)
0.0 1.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 14.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 3.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.0 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 69.9 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 3.7 GO:0042936 dipeptide transporter activity(GO:0042936)
1.2 6.1 GO:0043532 angiostatin binding(GO:0043532)
1.1 30.6 GO:0008432 JUN kinase binding(GO:0008432)
1.1 7.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 4.7 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.7 26.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 1.4 GO:0035939 microsatellite binding(GO:0035939)
0.7 4.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.7 3.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.6 2.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.6 9.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 25.4 GO:0070888 E-box binding(GO:0070888)
0.6 2.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.5 3.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 9.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.5 5.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 2.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 6.4 GO:0035173 histone kinase activity(GO:0035173)
0.4 8.0 GO:0001848 complement binding(GO:0001848)
0.4 1.6 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4 7.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.3 11.6 GO:0017091 AU-rich element binding(GO:0017091)
0.3 16.9 GO:0030507 spectrin binding(GO:0030507)
0.3 41.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 4.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 6.5 GO:0042605 peptide antigen binding(GO:0042605)
0.2 3.3 GO:0032452 histone demethylase activity(GO:0032452)
0.2 3.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 1.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 4.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 3.6 GO:0035198 miRNA binding(GO:0035198)
0.2 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.4 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 18.4 GO:0001047 core promoter binding(GO:0001047)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 3.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 7.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0002135 CTP binding(GO:0002135)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 8.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 2.9 GO:0003774 motor activity(GO:0003774)
0.0 10.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 28.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.5 6.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 17.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.3 25.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 6.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.2 8.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.2 16.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 7.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 3.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 5.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.6 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 5.1 PID_PLK1_PATHWAY PLK1 signaling events
0.1 9.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 4.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 3.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 0.5 PID_MYC_PATHWAY C-MYC pathway
0.1 0.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 3.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.2 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 4.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.6 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 19.0 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.6 9.8 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 19.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.4 13.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 3.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.3 2.5 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 2.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 7.2 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 8.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 5.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.2 2.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 5.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 11.4 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 10.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 5.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 5.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 8.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 6.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 9.0 REACTOME_MEIOSIS Genes involved in Meiosis
0.1 1.1 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.8 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.0 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 4.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.9 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 6.1 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)