Motif ID: Sox8
Z-value: 0.390
Transcription factors associated with Sox8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox8 | ENSMUSG00000024176.4 | Sox8 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox8 | mm10_v2_chr17_-_25570678_25570694 | -0.61 | 7.2e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.8 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
0.1 | 0.4 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
0.1 | 0.3 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
0.1 | 1.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.1 | 0.8 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
0.0 | 0.5 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.0 | 0.3 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
0.0 | 0.1 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.0 | 0.6 | GO:0070842 | aggresome assembly(GO:0070842) |
0.0 | 0.2 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.0 | 0.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.2 | GO:2001184 | regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184) |
0.0 | 0.2 | GO:0001927 | exocyst assembly(GO:0001927) |
0.0 | 0.1 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.8 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.8 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.0 | 0.5 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.1 | GO:0071942 | XPC complex(GO:0071942) |
0.0 | 0.5 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 1.2 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
0.0 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.4 | GO:0035939 | microsatellite binding(GO:0035939) |
0.1 | 1.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.1 | 0.5 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.1 | 0.8 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.1 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.0 | 0.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.2 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.0 | 0.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.1 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
0.0 | 0.8 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 1.5 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.5 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.2 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.0 | 0.5 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |