Motif ID: Spdef

Z-value: 0.523


Transcription factors associated with Spdef:

Gene SymbolEntrez IDGene Name
Spdef ENSMUSG00000024215.7 Spdef

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spdefmm10_v2_chr17_-_27728889_27728956-0.163.4e-01Click!


Activity profile for motif Spdef.

activity profile for motif Spdef


Sorted Z-values histogram for motif Spdef

Sorted Z-values for motif Spdef



Network of associatons between targets according to the STRING database.



First level regulatory network of Spdef

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_58813359 2.316 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr14_+_28511344 1.426 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr15_-_89170688 1.298 ENSMUST00000060808.9
Plxnb2
plexin B2
chr9_+_65908967 1.270 ENSMUST00000034949.3
ENSMUST00000154589.1
Csnk1g1

casein kinase 1, gamma 1

chr9_+_80165079 1.263 ENSMUST00000184480.1
Myo6
myosin VI
chr9_+_80165013 1.070 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr9_+_30427329 1.008 ENSMUST00000164099.1
Snx19
sorting nexin 19
chr2_-_167492826 0.994 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr3_-_90243073 0.962 ENSMUST00000107369.1
Creb3l4
cAMP responsive element binding protein 3-like 4
chr15_-_99820072 0.944 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr13_-_21531032 0.941 ENSMUST00000156674.2
ENSMUST00000110481.2
Zkscan8

zinc finger with KRAB and SCAN domains 8

chr12_-_102878406 0.868 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr9_-_65908676 0.852 ENSMUST00000119245.1
ENSMUST00000134338.1
ENSMUST00000179395.1
Trip4


thyroid hormone receptor interactor 4


chr18_+_34861200 0.827 ENSMUST00000165033.1
Egr1
early growth response 1
chr10_+_17723220 0.733 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr3_-_84582616 0.730 ENSMUST00000143514.1
Arfip1
ADP-ribosylation factor interacting protein 1
chrX_+_101254528 0.722 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr14_+_54254124 0.705 ENSMUST00000180359.1
Abhd4
abhydrolase domain containing 4
chr13_-_21531084 0.699 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr4_-_107923519 0.686 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr17_-_32947372 0.667 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr3_-_84582476 0.641 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr17_+_88626569 0.640 ENSMUST00000150023.1
Ston1
stonin 1
chr11_-_94474088 0.637 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr2_-_18392736 0.633 ENSMUST00000091418.5
ENSMUST00000166495.1
Dnajc1

DnaJ (Hsp40) homolog, subfamily C, member 1

chr9_+_27299205 0.632 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr2_+_62664279 0.629 ENSMUST00000028257.2
Gca
grancalcin
chr3_+_96576984 0.606 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr1_+_61638819 0.606 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr5_+_111733924 0.604 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr12_-_85339346 0.594 ENSMUST00000040992.7
Nek9
NIMA (never in mitosis gene a)-related expressed kinase 9
chr13_+_12395362 0.594 ENSMUST00000059270.8
Heatr1
HEAT repeat containing 1
chr9_+_32224457 0.575 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr5_-_69592274 0.566 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chr12_-_54999102 0.561 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr4_-_130279205 0.555 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr2_-_26445175 0.542 ENSMUST00000114082.2
ENSMUST00000091252.4
Sec16a

SEC16 homolog A (S. cerevisiae)

chr17_-_35700520 0.542 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr10_-_95416850 0.532 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr8_+_113635787 0.528 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chrX_-_102505359 0.521 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr17_+_35049966 0.509 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr1_+_163929765 0.503 ENSMUST00000027876.4
ENSMUST00000170359.1
Scyl3

SCY1-like 3 (S. cerevisiae)

chr5_+_66968961 0.502 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr6_-_86793522 0.502 ENSMUST00000001187.8
Anxa4
annexin A4
chr5_+_137745730 0.502 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr4_+_44756609 0.499 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr7_-_73537621 0.496 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr2_-_121171107 0.495 ENSMUST00000163766.1
ENSMUST00000146243.1
Zscan29

zinc finger SCAN domains 29

chr2_+_35132194 0.495 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr13_+_40886758 0.490 ENSMUST00000069958.7
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr18_+_12643329 0.489 ENSMUST00000025294.7
Ttc39c
tetratricopeptide repeat domain 39C
chr17_-_84466186 0.488 ENSMUST00000047524.8
Thada
thyroid adenoma associated
chr1_+_138963709 0.479 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr5_+_137745967 0.476 ENSMUST00000100539.3
Tsc22d4
TSC22 domain family, member 4
chr9_+_118040509 0.475 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chrX_-_134276969 0.472 ENSMUST00000087541.5
ENSMUST00000087540.3
Trmt2b

TRM2 tRNA methyltransferase 2B

chr2_-_160872985 0.468 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr17_-_35074485 0.467 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr8_+_113635550 0.464 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr8_+_109778554 0.462 ENSMUST00000093157.6
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr7_-_80232479 0.440 ENSMUST00000123279.1
Cib1
calcium and integrin binding 1 (calmyrin)
chr11_-_58330319 0.440 ENSMUST00000065533.2
Gm9900
predicted gene 9900
chr19_+_40894692 0.439 ENSMUST00000050092.6
Zfp518a
zinc finger protein 518A
chr8_+_109778863 0.439 ENSMUST00000034171.8
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr11_-_75454656 0.438 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr1_-_84839304 0.435 ENSMUST00000027421.6
Trip12
thyroid hormone receptor interactor 12
chr5_-_69592311 0.435 ENSMUST00000031117.6
Gnpda2
glucosamine-6-phosphate deaminase 2
chr11_-_83302586 0.433 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr5_+_138085083 0.427 ENSMUST00000019660.4
ENSMUST00000066617.5
ENSMUST00000110963.1
Zkscan1


zinc finger with KRAB and SCAN domains 1


chr7_+_127876796 0.426 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chrX_-_134276888 0.424 ENSMUST00000113252.1
Trmt2b
TRM2 tRNA methyltransferase 2B
chr4_-_118409219 0.422 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr17_+_26676390 0.411 ENSMUST00000015719.8
Atp6v0e
ATPase, H+ transporting, lysosomal V0 subunit E
chr9_+_118040576 0.410 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chr8_-_64205970 0.408 ENSMUST00000066166.4
Tll1
tolloid-like
chr11_+_60777525 0.404 ENSMUST00000056907.6
ENSMUST00000102667.3
Smcr8

Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)

chr2_-_120850598 0.402 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr10_+_77622363 0.396 ENSMUST00000172772.1
Ube2g2
ubiquitin-conjugating enzyme E2G 2
chr2_+_3424123 0.390 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr13_+_77135513 0.375 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr14_-_70207637 0.374 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr19_+_23687385 0.374 ENSMUST00000099560.3
Ptar1
protein prenyltransferase alpha subunit repeat containing 1
chr2_-_160872829 0.371 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr5_+_57718021 0.368 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr3_-_122984404 0.364 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr17_+_26676405 0.363 ENSMUST00000167352.1
Atp6v0e
ATPase, H+ transporting, lysosomal V0 subunit E
chr5_+_105732063 0.362 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr11_-_98149551 0.358 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr9_+_45055166 0.355 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr2_+_145785980 0.354 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr3_+_79629074 0.352 ENSMUST00000029388.8
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr8_+_85840971 0.352 ENSMUST00000053771.7
ENSMUST00000161850.1
Phkb

phosphorylase kinase beta

chr2_+_164805082 0.351 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr7_+_127841817 0.347 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr9_+_58129062 0.346 ENSMUST00000085677.2
Stra6
stimulated by retinoic acid gene 6
chr7_+_130774069 0.344 ENSMUST00000048453.5
Btbd16
BTB (POZ) domain containing 16
chr17_+_28272191 0.341 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr5_+_66968559 0.340 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr4_-_119174178 0.339 ENSMUST00000106355.3
Zfp691
zinc finger protein 691
chr9_+_58129321 0.333 ENSMUST00000034880.3
Stra6
stimulated by retinoic acid gene 6
chr8_+_125995102 0.330 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr7_+_27591705 0.328 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr17_+_32506446 0.327 ENSMUST00000165999.1
Cyp4f17
cytochrome P450, family 4, subfamily f, polypeptide 17
chr10_-_93311073 0.327 ENSMUST00000008542.5
Elk3
ELK3, member of ETS oncogene family
chr10_+_77622275 0.321 ENSMUST00000174510.1
ENSMUST00000172813.1
Ube2g2

ubiquitin-conjugating enzyme E2G 2

chrX_+_110814390 0.318 ENSMUST00000078229.3
Pou3f4
POU domain, class 3, transcription factor 4
chr7_-_27355944 0.317 ENSMUST00000003857.6
Shkbp1
Sh3kbp1 binding protein 1
chr4_-_4793275 0.316 ENSMUST00000084949.2
Impad1
inositol monophosphatase domain containing 1
chr11_-_103412668 0.316 ENSMUST00000041272.9
Plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr17_-_29007925 0.315 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr6_-_30509706 0.314 ENSMUST00000064330.6
ENSMUST00000102991.2
ENSMUST00000115157.1
ENSMUST00000148638.1
Tmem209



transmembrane protein 209



chr11_+_83299005 0.313 ENSMUST00000176944.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr9_+_65032722 0.311 ENSMUST00000167773.1
Dpp8
dipeptidylpeptidase 8
chr13_+_40859768 0.311 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr18_+_36783222 0.310 ENSMUST00000019287.8
Hars2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr9_+_118040475 0.303 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chrX_+_38189829 0.300 ENSMUST00000131124.1
Zbtb33
zinc finger and BTB domain containing 33
chr2_-_52742169 0.296 ENSMUST00000102759.1
ENSMUST00000127316.1
Stam2

signal transducing adaptor molecule (SH3 domain and ITAM motif) 2

chr3_-_63964659 0.296 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr5_-_146220901 0.294 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr9_+_119402444 0.292 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr5_+_105731755 0.292 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chrX_+_134686519 0.290 ENSMUST00000124226.2
Armcx4
armadillo repeat containing, X-linked 4
chr3_+_135825648 0.283 ENSMUST00000180196.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr6_+_29348069 0.279 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
Calu


calumenin


chr1_-_163725123 0.278 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr1_+_36307745 0.276 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr3_+_135825788 0.276 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr14_-_75754475 0.275 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr9_+_122888471 0.274 ENSMUST00000063980.6
Zkscan7
zinc finger with KRAB and SCAN domains 7
chr2_-_52742142 0.273 ENSMUST00000138290.1
Stam2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chrX_-_75416533 0.273 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr18_-_73703739 0.267 ENSMUST00000025393.7
Smad4
SMAD family member 4
chr4_-_63403330 0.267 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr17_+_33929514 0.267 ENSMUST00000047503.9
Rgl2
ral guanine nucleotide dissociation stimulator-like 2
chr7_+_127841752 0.265 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr13_-_59823072 0.262 ENSMUST00000071703.4
Zcchc6
zinc finger, CCHC domain containing 6
chr19_+_6306456 0.262 ENSMUST00000025681.7
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr6_-_97179100 0.261 ENSMUST00000095664.3
Tmf1
TATA element modulatory factor 1
chr10_-_95324072 0.260 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr11_+_97050811 0.260 ENSMUST00000168565.1
Osbpl7
oxysterol binding protein-like 7
chr16_-_44016387 0.260 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr9_+_57560934 0.257 ENSMUST00000045791.9
Scamp2
secretory carrier membrane protein 2
chr8_+_105305572 0.256 ENSMUST00000109375.2
Elmo3
engulfment and cell motility 3
chr5_-_146221426 0.256 ENSMUST00000161859.1
Rnf6
ring finger protein (C3H2C3 type) 6
chr18_-_46597299 0.255 ENSMUST00000036030.7
Tmed7
transmembrane emp24 protein transport domain containing 7
chr5_-_146221391 0.254 ENSMUST00000161574.1
Rnf6
ring finger protein (C3H2C3 type) 6
chr13_-_19619820 0.254 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr11_+_117232254 0.254 ENSMUST00000106354.2
Sept9
septin 9
chr5_+_34543365 0.252 ENSMUST00000101316.3
Sh3bp2
SH3-domain binding protein 2
chr19_+_46599081 0.248 ENSMUST00000138302.2
ENSMUST00000099376.4
Wbp1l

WW domain binding protein 1 like

chr3_-_32365608 0.248 ENSMUST00000168566.1
Zmat3
zinc finger matrin type 3
chr8_-_69996326 0.243 ENSMUST00000177851.1
ENSMUST00000065169.4
Gatad2a

GATA zinc finger domain containing 2A

chr11_+_83302817 0.241 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr6_+_14901344 0.241 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr2_+_32151074 0.240 ENSMUST00000036691.7
ENSMUST00000069817.8
Prrc2b

proline-rich coiled-coil 2B

chr7_+_45705088 0.240 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr5_-_86172747 0.237 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr9_+_32224246 0.235 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr14_-_57890242 0.235 ENSMUST00000089473.3
Zdhhc20
zinc finger, DHHC domain containing 20
chr13_-_77135416 0.234 ENSMUST00000159462.1
ENSMUST00000151524.2
Ankrd32

ankyrin repeat domain 32

chr18_-_10610346 0.234 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr15_+_35371498 0.233 ENSMUST00000048646.7
Vps13b
vacuolar protein sorting 13B (yeast)
chr2_+_106693185 0.232 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr12_+_86082555 0.232 ENSMUST00000054565.6
Ift43
intraflagellar transport 43 homolog (Chlamydomonas)
chr2_-_66410064 0.232 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr5_-_140830430 0.230 ENSMUST00000000153.4
Gna12
guanine nucleotide binding protein, alpha 12
chr15_-_36608959 0.229 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr10_-_128547722 0.226 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr12_+_102283036 0.226 ENSMUST00000056950.7
Rin3
Ras and Rab interactor 3
chr17_-_57247632 0.225 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr12_-_84361802 0.224 ENSMUST00000021659.1
ENSMUST00000065536.2
Fam161b

family with sequence similarity 161, member B

chrX_+_100625737 0.221 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr8_+_47713266 0.219 ENSMUST00000180928.1
E030037K01Rik
RIKEN cDNA E030037K01 gene
chr2_+_6322621 0.218 ENSMUST00000114937.1
Usp6nl
USP6 N-terminal like
chr14_+_52197502 0.218 ENSMUST00000180857.1
Gm26590
predicted gene, 26590
chrX_+_74429671 0.217 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
Ikbkg


inhibitor of kappaB kinase gamma


chr4_-_43025756 0.217 ENSMUST00000098109.2
Pigo
phosphatidylinositol glycan anchor biosynthesis, class O
chr7_+_27233003 0.217 ENSMUST00000003860.6
ENSMUST00000108378.3
Adck4

aarF domain containing kinase 4

chr18_+_42275353 0.217 ENSMUST00000046972.7
ENSMUST00000091920.5
Rbm27

RNA binding motif protein 27

chr6_-_57692007 0.216 ENSMUST00000053386.5
ENSMUST00000185014.1
Pyurf
PYURF
Pigy upstream reading frame
protein preY, mitochondrial precursor
chr8_-_83332416 0.216 ENSMUST00000177594.1
ENSMUST00000053902.3
Elmod2

ELMO/CED-12 domain containing 2

chr1_+_139422196 0.215 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr1_-_172082757 0.213 ENSMUST00000003550.4
Ncstn
nicastrin
chr14_-_52197216 0.212 ENSMUST00000046709.7
Supt16
suppressor of Ty 16
chr11_+_97050594 0.208 ENSMUST00000090020.5
Osbpl7
oxysterol binding protein-like 7
chr4_+_155582476 0.208 ENSMUST00000105612.1
Nadk
NAD kinase
chr19_-_7295394 0.208 ENSMUST00000025921.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr9_+_108296853 0.207 ENSMUST00000035230.5
Amt
aminomethyltransferase
chr9_-_21918089 0.205 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
Rab3d



RAB3D, member RAS oncogene family



chrX_-_12762069 0.205 ENSMUST00000096495.4
ENSMUST00000076016.5
Med14

mediator complex subunit 14

chr9_+_65032413 0.204 ENSMUST00000034960.6
Dpp8
dipeptidylpeptidase 8
chr11_+_102189620 0.204 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr4_-_116627921 0.203 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr10_-_22731918 0.202 ENSMUST00000095794.3
Tbpl1
TATA box binding protein-like 1
chr13_-_41847482 0.200 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr12_+_76072016 0.197 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr4_-_123750236 0.197 ENSMUST00000102636.3
Akirin1
akirin 1
chr1_-_121328024 0.196 ENSMUST00000003818.7
Insig2
insulin induced gene 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.3 1.0 GO:0019085 early viral transcription(GO:0019085)
0.3 0.9 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.3 1.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 0.8 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.2 0.6 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.2 0.7 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2 0.5 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 2.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 0.8 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 0.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.7 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 0.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.1 0.4 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.1 1.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.8 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743)
0.1 0.7 GO:0070317 negative regulation of smooth muscle cell differentiation(GO:0051151) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.7 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.7 GO:0006691 leukotriene metabolic process(GO:0006691)
0.1 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 1.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.9 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.6 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.3 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 1.1 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.7 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.5 GO:0006891 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.4 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 2.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.6 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.4 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 2.3 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 3.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.8 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules