Motif ID: Spic

Z-value: 1.450


Transcription factors associated with Spic:

Gene SymbolEntrez IDGene Name
Spic ENSMUSG00000004359.10 Spic

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spicmm10_v2_chr10_-_88683021_88683025-0.067.1e-01Click!


Activity profile for motif Spic.

activity profile for motif Spic


Sorted Z-values histogram for motif Spic

Sorted Z-values for motif Spic



Network of associatons between targets according to the STRING database.



First level regulatory network of Spic

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_136892867 15.524 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr4_-_136886187 12.472 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr1_-_171234290 10.955 ENSMUST00000079957.6
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr6_+_5725639 10.205 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_-_56978534 9.413 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_95526777 8.358 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr6_+_137410721 7.643 ENSMUST00000167002.1
Ptpro
protein tyrosine phosphatase, receptor type, O
chr15_-_66812593 7.638 ENSMUST00000100572.3
Sla
src-like adaptor
chr4_+_130913120 7.372 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr4_+_130913264 6.719 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr19_+_12460749 5.897 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr1_-_170976112 5.171 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fcgr2b


Fc receptor, IgG, low affinity IIb


chr10_-_117282262 4.825 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr14_+_57524734 4.499 ENSMUST00000089494.4
Il17d
interleukin 17D
chr12_-_4592927 4.471 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr8_-_122432924 4.414 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr1_-_171059390 4.410 ENSMUST00000164044.1
ENSMUST00000169017.1
Fcgr3

Fc receptor, IgG, low affinity III

chr11_+_78324200 4.060 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr11_-_106715251 3.884 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr14_+_80000292 3.857 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr7_-_90129339 3.712 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr2_+_57238297 3.697 ENSMUST00000112618.2
ENSMUST00000028167.2
Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr7_+_28982832 3.456 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr8_+_66386292 3.453 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr2_-_25319095 3.416 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr4_-_118489755 3.269 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chrX_+_8271133 3.252 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr12_+_75308308 3.204 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr19_-_11604828 3.175 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr16_+_91406235 2.933 ENSMUST00000023691.5
Il10rb
interleukin 10 receptor, beta
chr6_-_136941694 2.921 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr15_+_103453782 2.887 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr4_-_49845549 2.827 ENSMUST00000093859.4
ENSMUST00000076674.3
Grin3a

glutamate receptor ionotropic, NMDA3A

chr8_+_107056870 2.781 ENSMUST00000034392.5
ENSMUST00000170962.1
Nip7

nuclear import 7 homolog (S. cerevisiae)

chr13_-_49309217 2.650 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr10_-_89732253 2.524 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr12_+_77238093 2.425 ENSMUST00000177595.1
ENSMUST00000171770.2
Fut8

fucosyltransferase 8

chr1_-_87573825 2.420 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr3_-_106790143 2.323 ENSMUST00000038845.8
Cd53
CD53 antigen
chr10_-_61383523 2.322 ENSMUST00000020289.8
Pald1
phosphatase domain containing, paladin 1
chr17_+_33955902 2.312 ENSMUST00000173196.2
Vps52
vacuolar protein sorting 52 (yeast)
chr16_+_36934976 2.205 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr7_+_28833975 2.177 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr19_-_45591820 2.165 ENSMUST00000160003.1
ENSMUST00000162879.1
Fbxw4

F-box and WD-40 domain protein 4

chr17_+_33955812 2.144 ENSMUST00000025178.9
ENSMUST00000114330.2
Vps52

vacuolar protein sorting 52 (yeast)

chr1_+_87620334 2.143 ENSMUST00000042275.8
ENSMUST00000168783.1
Inpp5d

inositol polyphosphate-5-phosphatase D

chr19_-_6909599 2.096 ENSMUST00000173091.1
Prdx5
peroxiredoxin 5
chr6_-_136941887 2.076 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr11_+_102836296 2.067 ENSMUST00000021302.8
ENSMUST00000107072.1
Higd1b

HIG1 domain family, member 1B

chr13_+_30659999 2.066 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
Dusp22


dual specificity phosphatase 22


chr9_-_116175318 2.025 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr19_+_4231899 1.944 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr1_-_179546261 1.930 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr3_-_96293953 1.928 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr7_+_126695942 1.911 ENSMUST00000106369.1
Bola2
bolA-like 2 (E. coli)
chr7_-_126704179 1.876 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr6_-_48708206 1.874 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr11_-_78984831 1.839 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr7_-_126704736 1.836 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr11_+_70540260 1.816 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
Pld2


phospholipase D2


chr3_-_59262825 1.810 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr15_+_25843264 1.800 ENSMUST00000022881.7
Fam134b
family with sequence similarity 134, member B
chr9_+_58253164 1.794 ENSMUST00000034883.5
Stoml1
stomatin-like 1
chr4_-_40722307 1.789 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr6_-_136941494 1.789 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr17_+_29268788 1.780 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr7_+_5080214 1.758 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr19_-_6910088 1.753 ENSMUST00000025904.5
Prdx5
peroxiredoxin 5
chr7_-_126704522 1.747 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr5_+_122391878 1.682 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr12_-_78980758 1.645 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr6_+_48684570 1.641 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
Gimap4




GTPase, IMAP family member 4




chr16_+_35154870 1.640 ENSMUST00000114913.1
Adcy5
adenylate cyclase 5
chr7_+_122133036 1.617 ENSMUST00000033156.4
Dctn5
dynactin 5
chr17_-_35916323 1.595 ENSMUST00000172642.1
ENSMUST00000174807.1
ENSMUST00000174349.1
ENSMUST00000025305.9
ENSMUST00000113782.3
Mrps18b




mitochondrial ribosomal protein S18B




chr7_-_100856289 1.565 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr19_-_6084941 1.562 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1

zinc finger like protein 1

chr4_-_133277730 1.541 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr1_+_171840607 1.531 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr9_-_20644726 1.527 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
Fbxl12




F-box and leucine-rich repeat protein 12




chr8_-_73353477 1.526 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr17_-_33955658 1.515 ENSMUST00000174609.2
ENSMUST00000008812.7
Rps18

ribosomal protein S18

chr15_-_89128634 1.505 ENSMUST00000082197.5
Hdac10
histone deacetylase 10
chr19_-_6084873 1.423 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr15_-_80264276 1.413 ENSMUST00000052499.7
Rps19bp1
ribosomal protein S19 binding protein 1
chrX_-_8175890 1.398 ENSMUST00000143984.1
Tbc1d25
TBC1 domain family, member 25
chr8_+_84701430 1.397 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr19_+_6941861 1.391 ENSMUST00000025910.5
Bad
BCL2-associated agonist of cell death
chr7_+_28440927 1.357 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr4_-_117887292 1.352 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr16_+_13903152 1.349 ENSMUST00000128757.1
Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr7_-_100964371 1.335 ENSMUST00000060174.4
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_+_85080939 1.325 ENSMUST00000140621.1
BC056474
cDNA sequence BC056474
chr2_+_55437100 1.325 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr8_-_70897407 1.320 ENSMUST00000054220.8
Rpl18a
ribosomal protein L18A
chr1_+_135147615 1.312 ENSMUST00000125774.1
Arl8a
ADP-ribosylation factor-like 8A
chr19_-_6084679 1.297 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr12_+_84361636 1.296 ENSMUST00000110276.1
Coq6
coenzyme Q6 homolog (yeast)
chr8_+_125730005 1.290 ENSMUST00000143504.1
Ntpcr
nucleoside-triphosphatase, cancer-related
chr9_-_110476637 1.267 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr2_-_91070180 1.251 ENSMUST00000153367.1
ENSMUST00000079976.3
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr12_+_84361968 1.250 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr3_+_122419772 1.244 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr15_-_82047579 1.228 ENSMUST00000166578.1
ENSMUST00000080622.7
Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr6_+_17749170 1.222 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr8_-_26015577 1.219 ENSMUST00000016138.9
Fnta
farnesyltransferase, CAAX box, alpha
chr12_+_4592992 1.219 ENSMUST00000062580.7
Itsn2
intersectin 2
chr11_-_78984946 1.203 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr4_-_117887279 1.194 ENSMUST00000132073.1
Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
chr6_+_125215551 1.190 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr7_+_80261202 1.189 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chr6_-_124965485 1.184 ENSMUST00000112439.2
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr12_+_84362029 1.166 ENSMUST00000110278.1
ENSMUST00000145522.1
Coq6

coenzyme Q6 homolog (yeast)

chr6_-_124965403 1.162 ENSMUST00000129446.1
ENSMUST00000032220.8
Cops7a

COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)

chr5_-_116024452 1.159 ENSMUST00000031486.7
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr10_+_80292453 1.153 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr5_-_138171216 1.133 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_-_124850670 1.131 ENSMUST00000163946.1
ENSMUST00000106190.3
1110065P20Rik

RIKEN cDNA 1110065P20 gene

chr15_+_25984359 1.114 ENSMUST00000061875.6
Zfp622
zinc finger protein 622
chr2_-_91070283 1.099 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr13_-_90089513 1.095 ENSMUST00000160232.1
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chrX_+_7884244 1.090 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr12_-_80643799 1.089 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr3_-_67463828 1.087 ENSMUST00000058981.2
Lxn
latexin
chr5_-_92435114 1.086 ENSMUST00000135112.1
Nup54
nucleoporin 54
chr5_-_116024475 1.084 ENSMUST00000111999.1
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr7_-_105640308 1.080 ENSMUST00000133519.1
ENSMUST00000084782.2
ENSMUST00000131446.1
Arfip2


ADP-ribosylation factor interacting protein 2


chr17_+_57279094 1.077 ENSMUST00000169220.2
ENSMUST00000005889.9
ENSMUST00000112870.4
Vav1


vav 1 oncogene


chr3_+_95499273 1.076 ENSMUST00000015664.3
Ctsk
cathepsin K
chr11_-_69662625 1.073 ENSMUST00000018905.5
Mpdu1
mannose-P-dolichol utilization defect 1
chr8_+_94037198 1.065 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1


2-oxoglutarate and iron-dependent oxygenase domain containing 1


chr13_+_98263187 1.063 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr14_-_65593079 1.045 ENSMUST00000022609.5
Elp3
elongator acetyltransferase complex subunit 3
chr15_+_78877172 1.032 ENSMUST00000041587.7
Gga1
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr12_+_55398775 1.030 ENSMUST00000021412.8
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr10_-_30655859 1.030 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr11_-_69662564 1.029 ENSMUST00000129224.1
ENSMUST00000155200.1
Mpdu1

mannose-P-dolichol utilization defect 1

chr12_-_24493656 1.028 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr5_-_138171248 1.024 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_+_91650169 1.019 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr10_-_39899238 1.000 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr2_-_130424242 0.997 ENSMUST00000089581.4
Pced1a
PC-esterase domain containing 1A
chr9_+_64235201 0.996 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr4_+_105790534 0.993 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr1_+_152807877 0.988 ENSMUST00000027754.6
Ncf2
neutrophil cytosolic factor 2
chrX_+_7884022 0.984 ENSMUST00000115660.4
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr13_+_98263242 0.976 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr1_-_37496095 0.975 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr16_+_32419696 0.970 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2

Tctex1 domain containing 2

chr17_+_74489492 0.963 ENSMUST00000024873.6
Yipf4
Yip1 domain family, member 4
chr13_-_58128542 0.960 ENSMUST00000007980.6
Hnrnpa0
heterogeneous nuclear ribonucleoprotein A0
chr11_-_103344651 0.955 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr13_+_98263105 0.938 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr1_+_167308649 0.937 ENSMUST00000097473.4
Tmco1
transmembrane and coiled-coil domains 1
chr19_-_41896132 0.931 ENSMUST00000038677.3
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr4_-_120815703 0.922 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr15_-_12592556 0.916 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr2_+_36230426 0.903 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr17_-_29347902 0.896 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr11_+_70130329 0.890 ENSMUST00000041550.5
ENSMUST00000165951.1
Mgl2

macrophage galactose N-acetyl-galactosamine specific lectin 2

chr6_+_113378113 0.878 ENSMUST00000171058.1
ENSMUST00000156898.1
Arpc4

actin related protein 2/3 complex, subunit 4

chr6_+_123229843 0.870 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
Clec4n


C-type lectin domain family 4, member n


chr17_+_29360923 0.870 ENSMUST00000024810.6
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr6_+_113604749 0.862 ENSMUST00000035725.5
Brk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr12_+_28751798 0.861 ENSMUST00000035657.7
Tssc1
tumor suppressing subtransferable candidate 1
chr1_-_171294937 0.859 ENSMUST00000111302.3
ENSMUST00000080001.2
Ufc1

ubiquitin-fold modifier conjugating enzyme 1

chr4_+_45297127 0.853 ENSMUST00000044673.2
ENSMUST00000144781.1
Trmt10b

tRNA methyltransferase 10B

chr1_+_33669816 0.850 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr13_-_90089556 0.843 ENSMUST00000022115.7
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chrX_+_7884321 0.822 ENSMUST00000096514.3
ENSMUST00000123277.1
Slc35a2

solute carrier family 35 (UDP-galactose transporter), member A2

chr7_-_79743034 0.820 ENSMUST00000032761.7
Pex11a
peroxisomal biogenesis factor 11 alpha
chr2_+_130424321 0.811 ENSMUST00000128994.1
ENSMUST00000028900.9
Vps16

vacuolar protein sorting 16 (yeast)

chr1_-_183297008 0.811 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr6_-_72362382 0.794 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
Rnf181


ring finger protein 181


chr2_+_91650116 0.792 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr17_+_35916541 0.788 ENSMUST00000087211.2
Ppp1r10
protein phosphatase 1, regulatory subunit 10
chr14_-_68655804 0.784 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr5_+_124552905 0.778 ENSMUST00000111438.1
Ddx55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr11_+_70540064 0.772 ENSMUST00000157075.1
Pld2
phospholipase D2
chr17_+_74717743 0.769 ENSMUST00000024882.6
Ttc27
tetratricopeptide repeat domain 27
chr12_+_87266696 0.766 ENSMUST00000021425.6
Ahsa1
AHA1, activator of heat shock protein ATPase 1
chr5_-_138170992 0.763 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_+_126695355 0.763 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr1_-_150392719 0.762 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr5_+_124552845 0.760 ENSMUST00000071057.7
Ddx55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr8_+_72219726 0.759 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr15_-_31601786 0.753 ENSMUST00000022842.8
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr6_-_124965207 0.743 ENSMUST00000148485.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr7_+_35397046 0.743 ENSMUST00000079414.5
Cep89
centrosomal protein 89
chr15_+_76368884 0.739 ENSMUST00000023213.6
Fam203a
family with sequence similarity 203, member A
chr14_-_55671873 0.728 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr10_-_81060134 0.724 ENSMUST00000005067.5
Sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr12_+_80644212 0.724 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr2_-_84715160 0.720 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr11_+_5955693 0.716 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr12_-_80260356 0.715 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr19_-_3282958 0.713 ENSMUST00000119292.1
ENSMUST00000025751.3
Ighmbp2

immunoglobulin mu binding protein 2

chr4_+_105789869 0.702 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr7_-_104315455 0.694 ENSMUST00000106837.1
ENSMUST00000106839.2
ENSMUST00000070943.6
Trim12a


tripartite motif-containing 12A


chr11_-_102469839 0.688 ENSMUST00000103086.3
Itga2b
integrin alpha 2b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.3 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
2.4 12.1 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
2.0 13.8 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
1.7 5.2 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
1.6 4.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.5 4.5 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
1.3 3.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
1.1 3.4 GO:1900673 olefin metabolic process(GO:1900673)
1.1 6.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.0 3.0 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
1.0 3.9 GO:0050904 diapedesis(GO:0050904)
1.0 2.9 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.9 10.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.9 5.5 GO:0032796 uropod organization(GO:0032796)
0.7 2.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.7 2.7 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.7 2.0 GO:2000561 CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
0.6 9.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6 3.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.6 2.4 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.6 12.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.6 8.4 GO:0010447 response to acidic pH(GO:0010447)
0.5 1.5 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.5 1.4 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.4 1.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 2.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 2.5 GO:0035878 nail development(GO:0035878)
0.4 1.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.4 4.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 1.8 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 2.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.3 0.7 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.3 0.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.3 1.8 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.3 0.9 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.3 0.9 GO:1904809 dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.3 2.5 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.3 1.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 2.5 GO:0071569 protein ufmylation(GO:0071569)
0.2 3.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 2.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 0.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 1.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 3.3 GO:0015816 glycine transport(GO:0015816)
0.2 1.3 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 3.8 GO:0000338 protein deneddylation(GO:0000338)
0.2 2.8 GO:0060134 prepulse inhibition(GO:0060134)
0.2 1.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 1.7 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 3.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 1.6 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.2 3.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.4 GO:0001955 blood vessel maturation(GO:0001955)
0.2 2.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 1.8 GO:0051014 actin filament severing(GO:0051014)
0.2 2.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 1.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.6 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.2 0.5 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.2 0.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 0.5 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.2 0.7 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 1.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 2.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.8 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0019085 early viral transcription(GO:0019085)
0.1 0.4 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.8 GO:0016557 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 3.3 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.9 GO:0006983 ER overload response(GO:0006983)
0.1 1.4 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 1.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 2.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.6 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.1 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.6 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 7.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 3.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 4.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0071476 cellular hypotonic response(GO:0071476)
0.1 2.4 GO:0007035 vacuolar acidification(GO:0007035)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 1.9 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.7 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:1905076 regulation of interleukin-17 secretion(GO:1905076)
0.1 11.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.3 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 3.9 GO:0042255 ribosome assembly(GO:0042255)
0.1 0.3 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 2.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.9 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 1.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.7 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 1.6 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 2.9 GO:0008643 carbohydrate transport(GO:0008643)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 2.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 2.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.7 GO:0002687 positive regulation of leukocyte migration(GO:0002687)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.1 5.5 GO:0043020 NADPH oxidase complex(GO:0043020)
1.0 4.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.9 4.5 GO:1990745 EARP complex(GO:1990745)
0.9 3.4 GO:0044307 dendritic branch(GO:0044307)
0.8 3.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.7 3.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 5.5 GO:0032426 stereocilium tip(GO:0032426)
0.5 3.0 GO:1990393 3M complex(GO:1990393)
0.5 1.4 GO:0032127 dense core granule membrane(GO:0032127)
0.4 1.8 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.4 2.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.4 1.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.4 1.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.4 28.2 GO:0005581 collagen trimer(GO:0005581)
0.4 2.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 5.0 GO:0042581 specific granule(GO:0042581)
0.3 1.8 GO:0097443 sorting endosome(GO:0097443)
0.3 3.7 GO:0031209 SCAR complex(GO:0031209)
0.2 1.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 2.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 1.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.2 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.2 2.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 4.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 5.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 0.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.0 GO:0033263 CORVET complex(GO:0033263)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.6 GO:0005869 dynactin complex(GO:0005869)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 3.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.1 GO:0034709 methylosome(GO:0034709)
0.1 25.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 2.3 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0019034 viral replication complex(GO:0019034)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 7.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 3.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 8.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 7.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 11.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 2.6 GO:0031526 brush border membrane(GO:0031526)
0.0 1.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0001726 ruffle(GO:0001726)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 6.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 2.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0031252 cell leading edge(GO:0031252)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 22.5 GO:0019864 immunoglobulin receptor activity(GO:0019763) IgG binding(GO:0019864)
1.6 4.8 GO:0003796 lysozyme activity(GO:0003796)
1.4 5.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.3 3.8 GO:0072541 peroxynitrite reductase activity(GO:0072541)
1.2 3.7 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.0 6.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9 5.2 GO:0016936 galactoside binding(GO:0016936)
0.7 2.9 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.7 4.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 6.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.6 10.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.5 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.5 5.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 2.9 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.5 1.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 3.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 2.1 GO:0051425 PTB domain binding(GO:0051425)
0.4 2.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4 1.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.4 3.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 3.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 2.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 0.9 GO:0071568 UFM1 transferase activity(GO:0071568)
0.3 1.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 8.8 GO:0043394 proteoglycan binding(GO:0043394)
0.2 0.7 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 3.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 7.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 0.7 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.2 8.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 1.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 2.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 4.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 1.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.7 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.1 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 3.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 4.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.0 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 7.6 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047) 7S RNA binding(GO:0008312)
0.1 1.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.1 3.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.6 GO:0019843 rRNA binding(GO:0019843)
0.0 2.0 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 3.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 4.9 GO:0005525 GTP binding(GO:0005525)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.8 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 7.5 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 24.1 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 32.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 9.0 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 9.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.2 6.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 5.5 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 2.6 PID_ARF_3PATHWAY Arf1 pathway
0.1 1.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.6 PID_EPO_PATHWAY EPO signaling pathway
0.1 4.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 0.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 7.3 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 1.3 ST_ADRENERGIC Adrenergic Pathway
0.0 7.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 3.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_CDC42_PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 28.0 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
2.8 8.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.8 11.0 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 3.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.3 8.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 5.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 3.9 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.2 2.8 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.2 1.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.5 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 3.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.6 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.7 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 3.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 2.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.9 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 15.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.0 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.2 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.7 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 6.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 5.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 0.7 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 2.0 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.0 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.9 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.5 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4