Motif ID: Srf

Z-value: 1.004


Transcription factors associated with Srf:

Gene SymbolEntrez IDGene Name
Srf ENSMUSG00000015605.5 Srf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Srfmm10_v2_chr17_-_46556158_46556188-0.202.4e-01Click!


Activity profile for motif Srf.

activity profile for motif Srf


Sorted Z-values histogram for motif Srf

Sorted Z-values for motif Srf



Network of associatons between targets according to the STRING database.



First level regulatory network of Srf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 7.235 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_+_43957678 3.372 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr4_+_43957401 3.144 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr14_+_5071040 2.976 ENSMUST00000163719.1
Gm8281
predicted gene, 8281
chr14_+_4726775 2.732 ENSMUST00000165619.1
Gm3252
predicted gene 3252
chr14_+_4415448 2.708 ENSMUST00000168866.1
Gm3164
predicted gene 3164
chr14_+_3652030 2.618 ENSMUST00000167430.1
Gm3020
predicted gene 3020
chr14_+_3412614 2.590 ENSMUST00000170123.1
Gm10409
predicted gene 10409
chr14_-_6889962 2.514 ENSMUST00000171906.1
Gm3667
predicted gene 3667
chr14_+_4334763 2.480 ENSMUST00000165466.1
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr10_-_120899067 2.430 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr14_+_3332627 2.428 ENSMUST00000177786.1
Gm2956
predicted gene 2956
chr14_+_4182576 2.404 ENSMUST00000164512.1
Gm2974
predicted gene 2974
chr14_+_3049285 2.354 ENSMUST00000166494.1
Gm2897
predicted gene 2897
chr14_-_7568566 2.324 ENSMUST00000163790.1
Gm3558
predicted gene 3558
chr14_+_3572023 2.282 ENSMUST00000178728.1
Gm3005
predicted gene 3005
chr14_-_5961745 2.172 ENSMUST00000163885.1
Gm3248
predicted gene 3248
chr14_-_6038209 2.155 ENSMUST00000164139.1
Gm8206
predicted gene 8206
chr14_-_7027449 2.153 ENSMUST00000170738.2
Gm10406
predicted gene 10406
chr14_-_5389049 2.132 ENSMUST00000177986.1
Gm3500
predicted gene 3500
chr14_-_6287250 2.110 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr4_+_137862237 2.074 ENSMUST00000102518.3
Ece1
endothelin converting enzyme 1
chr14_-_5880382 2.052 ENSMUST00000164484.1
Gm8237
predicted gene 8237
chr14_+_5501674 2.042 ENSMUST00000181562.1
Gm3488
predicted gene, 3488
chr5_+_30588078 1.940 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr2_+_127336152 1.938 ENSMUST00000028846.6
Dusp2
dual specificity phosphatase 2
chr7_-_142661305 1.908 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr14_-_7174533 1.900 ENSMUST00000172431.1
Gm3512
predicted gene 3512
chr14_+_3810074 1.825 ENSMUST00000170480.1
Gm3002
predicted gene 3002
chr19_+_53529100 1.795 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr14_+_4855576 1.788 ENSMUST00000166776.1
Gm3264
predicted gene 3264
chr5_-_24329556 1.780 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_-_7315049 1.756 ENSMUST00000165744.1
Gm3739
predicted gene 3739
chr3_+_68468162 1.552 ENSMUST00000182532.1
Schip1
schwannomin interacting protein 1
chr5_-_138996087 1.546 ENSMUST00000110897.1
Pdgfa
platelet derived growth factor, alpha
chr14_+_4110526 1.519 ENSMUST00000170207.1
Gm8108
predicted gene 8108
chr14_-_5741577 1.467 ENSMUST00000177556.1
Gm3373
predicted gene 3373
chr10_+_79988584 1.466 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr18_+_34861200 1.412 ENSMUST00000165033.1
Egr1
early growth response 1
chr14_-_6108665 1.347 ENSMUST00000165193.1
Gm3468
predicted gene 3468
chr7_-_137314394 1.316 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr14_-_19585135 1.312 ENSMUST00000170694.1
Gm2237
predicted gene 2237
chr4_+_148000722 1.221 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr7_+_101896817 1.158 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr10_+_67537861 1.076 ENSMUST00000048289.7
ENSMUST00000105438.2
ENSMUST00000130933.1
ENSMUST00000146986.1
Egr2



early growth response 2



chr13_+_64432479 1.032 ENSMUST00000021939.6
Cdk20
cyclin-dependent kinase 20
chr7_+_128246953 0.998 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr1_+_167618246 0.991 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr7_+_128246812 0.972 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr16_-_4880284 0.949 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr11_+_94741782 0.924 ENSMUST00000021240.6
Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr12_-_32953772 0.918 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr7_+_101896340 0.913 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr18_+_80253274 0.901 ENSMUST00000131780.1
ENSMUST00000157056.1
Pqlc1

PQ loop repeat containing 1

chr11_-_120348513 0.884 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr2_-_60881360 0.848 ENSMUST00000164147.1
ENSMUST00000112509.1
Rbms1

RNA binding motif, single stranded interacting protein 1

chr19_+_25406661 0.845 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr7_-_142661858 0.812 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr6_+_113378113 0.788 ENSMUST00000171058.1
ENSMUST00000156898.1
Arpc4

actin related protein 2/3 complex, subunit 4

chr5_+_90367204 0.777 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chr2_+_32395896 0.766 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr4_+_132351768 0.759 ENSMUST00000172202.1
Gm17300
predicted gene, 17300
chr5_-_145191511 0.758 ENSMUST00000161845.1
Atp5j2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr3_+_106113229 0.749 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr1_-_43163891 0.731 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr11_-_120731944 0.719 ENSMUST00000154565.1
ENSMUST00000026148.2
Cbr2

carbonyl reductase 2

chr12_+_85473883 0.649 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr8_-_47675130 0.642 ENSMUST00000080353.2
Ing2
inhibitor of growth family, member 2
chr11_+_19924403 0.636 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr1_-_33757711 0.617 ENSMUST00000044691.7
Bag2
BCL2-associated athanogene 2
chr3_-_152266320 0.608 ENSMUST00000046045.8
Nexn
nexilin
chr11_-_120348091 0.601 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr11_-_120348475 0.601 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr3_+_90072641 0.600 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr10_+_4266323 0.591 ENSMUST00000045730.5
Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr10_-_12861735 0.588 ENSMUST00000076817.4
Utrn
utrophin
chr8_-_47675556 0.580 ENSMUST00000125536.1
Ing2
inhibitor of growth family, member 2
chr14_-_29721835 0.580 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr7_-_119720742 0.529 ENSMUST00000033236.7
Thumpd1
THUMP domain containing 1
chr7_-_19310035 0.529 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr19_-_4928241 0.516 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr8_-_71381907 0.501 ENSMUST00000002466.8
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr7_+_119896292 0.479 ENSMUST00000106517.1
Lyrm1
LYR motif containing 1
chr2_-_164833438 0.468 ENSMUST00000042775.4
Neurl2
neuralized-like 2 (Drosophila)
chr15_-_36794498 0.457 ENSMUST00000110361.1
ENSMUST00000022894.7
ENSMUST00000110359.1
Ywhaz


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide


chrX_+_101449078 0.444 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr8_-_84237042 0.417 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr1_-_127677923 0.417 ENSMUST00000160616.1
Tmem163
transmembrane protein 163
chr14_+_74732384 0.413 ENSMUST00000176957.1
Esd
esterase D/formylglutathione hydrolase
chr12_-_110696289 0.385 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr10_-_111997204 0.382 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr6_-_113377376 0.380 ENSMUST00000043333.2
Tada3
transcriptional adaptor 3
chr6_-_113377510 0.373 ENSMUST00000099118.2
Tada3
transcriptional adaptor 3
chr1_+_63176818 0.297 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr7_+_119895836 0.297 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr10_+_90576872 0.292 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr6_-_113377866 0.279 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr17_-_27204357 0.268 ENSMUST00000055117.7
Lemd2
LEM domain containing 2
chr1_+_38987806 0.268 ENSMUST00000027247.5
Pdcl3
phosducin-like 3
chr4_-_122886044 0.266 ENSMUST00000106255.1
ENSMUST00000106257.3
Cap1

CAP, adenylate cyclase-associated protein 1 (yeast)

chr19_+_5447692 0.231 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr17_-_46153517 0.225 ENSMUST00000171172.1
Mad2l1bp
MAD2L1 binding protein
chr11_+_77462325 0.147 ENSMUST00000102493.1
Coro6
coronin 6
chr12_-_110696248 0.146 ENSMUST00000124156.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_-_152415044 0.145 ENSMUST00000099207.3
Zcchc3
zinc finger, CCHC domain containing 3
chr11_-_69662625 0.137 ENSMUST00000018905.5
Mpdu1
mannose-P-dolichol utilization defect 1
chr11_+_82911253 0.101 ENSMUST00000164945.1
ENSMUST00000018989.7
Unc45b

unc-45 homolog B (C. elegans)

chr9_+_75051977 0.077 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr6_-_132314757 0.060 ENSMUST00000048686.8
Prpmp5
proline-rich protein MP5
chr12_-_110695860 0.055 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_-_70669283 0.054 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7

sperm associated antigen 7

chr11_-_69662564 0.038 ENSMUST00000129224.1
ENSMUST00000155200.1
Mpdu1

mannose-P-dolichol utilization defect 1

chr5_-_142905816 0.017 ENSMUST00000171419.1
Actb
actin, beta
chr4_+_101986626 0.013 ENSMUST00000106914.1
Gm12789
predicted gene 12789
chr8_-_123894736 0.001 ENSMUST00000034453.4
Acta1
actin, alpha 1, skeletal muscle

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 1.4 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.7 2.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.6 2.5 GO:0060025 regulation of synaptic activity(GO:0060025)
0.6 2.4 GO:0030091 protein repair(GO:0030091)
0.5 1.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.4 3.0 GO:1902302 regulation of potassium ion export(GO:1902302)
0.3 2.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 2.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 1.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.2 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.1 2.1 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.6 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.1 1.6 GO:0001553 luteinization(GO:0001553)
0.1 5.0 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 1.9 GO:0001706 endoderm formation(GO:0001706)
0.1 0.7 GO:0060347 heart trabecula formation(GO:0060347)
0.1 2.6 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.6 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 1.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.5 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.0 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.8 GO:0006754 ATP biosynthetic process(GO:0006754)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 2.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.2 1.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 2.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.9 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 6.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4 1.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.4 1.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 1.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 3.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 1.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.6 GO:0002135 CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098)
0.1 2.7 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 5.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.8 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.8 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 2.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+