Motif ID: Stat1

Z-value: 0.497


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_52119499-0.454.8e-03Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_78499087 3.934 ENSMUST00000017488.4
Vtn
vitronectin
chr15_-_93519499 2.797 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr12_+_74297474 2.418 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr17_-_68004075 2.249 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr11_+_101245996 2.032 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr3_-_80802789 1.997 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr8_-_105568298 1.851 ENSMUST00000005849.5
Agrp
agouti related protein
chr15_-_37459327 1.818 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr4_-_136886187 1.785 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr15_-_37458523 1.735 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr4_-_64046925 1.674 ENSMUST00000107377.3
Tnc
tenascin C
chr9_+_20868628 1.513 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr7_-_78577771 1.476 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chrX_-_61185558 1.447 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr4_+_43401232 1.176 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr11_+_82035569 1.095 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr7_+_45783686 1.041 ENSMUST00000118564.1
ENSMUST00000133428.1
Lmtk3

lemur tyrosine kinase 3

chr3_-_10440054 1.035 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr17_-_45592569 1.000 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr7_+_24134148 0.987 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr16_+_91372783 0.950 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr13_+_109903089 0.950 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr9_+_86743616 0.947 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr7_+_45783883 0.945 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr19_-_46327121 0.926 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr16_-_42340595 0.913 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr2_+_150749036 0.901 ENSMUST00000094467.5
Entpd6
ectonucleoside triphosphate diphosphohydrolase 6
chr17_+_34187545 0.859 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_40349265 0.854 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr7_-_100856289 0.848 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr9_+_86743641 0.839 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr17_-_45592485 0.833 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr11_+_82101836 0.829 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr18_-_52529847 0.791 ENSMUST00000171470.1
Lox
lysyl oxidase
chr18_-_52529692 0.782 ENSMUST00000025409.7
Lox
lysyl oxidase
chr2_-_163750169 0.773 ENSMUST00000017841.3
Ada
adenosine deaminase
chr16_+_91372865 0.758 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr17_+_34187789 0.745 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr8_-_70776650 0.712 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr7_+_24112314 0.706 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr1_-_155417394 0.698 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr18_+_37320374 0.689 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chrX_+_7728439 0.673 ENSMUST00000033489.7
Praf2
PRA1 domain family 2
chr5_+_136919137 0.651 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr8_+_105326354 0.649 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr7_-_13053684 0.621 ENSMUST00000182490.1
Mzf1
myeloid zinc finger 1
chr9_+_45117813 0.591 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr2_-_168712853 0.579 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr7_-_126625676 0.561 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr1_+_34005872 0.558 ENSMUST00000182296.1
Dst
dystonin
chr13_-_34002784 0.553 ENSMUST00000166354.1
ENSMUST00000076532.7
ENSMUST00000171034.1
Serpinb6a


serine (or cysteine) peptidase inhibitor, clade B, member 6a


chr8_+_11728105 0.552 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr15_-_54919961 0.549 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr8_-_70608261 0.525 ENSMUST00000049908.9
Ssbp4
single stranded DNA binding protein 4
chr11_-_98729374 0.522 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr18_-_33463615 0.512 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr1_-_155417283 0.502 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr17_-_24527830 0.473 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr7_-_24316590 0.467 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr18_-_3281036 0.458 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr1_+_37890477 0.455 ENSMUST00000027256.5
Mrpl30
mitochondrial ribosomal protein L30
chr5_-_34513892 0.454 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr9_+_107296682 0.454 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr13_-_34002740 0.454 ENSMUST00000167237.1
ENSMUST00000168400.1
Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

chr17_-_24527925 0.447 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr15_-_54920115 0.446 ENSMUST00000171545.1
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr19_-_37207293 0.440 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr17_-_47834682 0.428 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr16_-_74411776 0.418 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr18_-_33464007 0.418 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr5_-_123140135 0.413 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr18_-_33463747 0.404 ENSMUST00000171533.1
Nrep
neuronal regeneration related protein
chr17_-_27728889 0.402 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chrX_+_48623737 0.400 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_-_45016224 0.398 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chrX_-_101419788 0.393 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr4_-_107178282 0.387 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr9_+_86571965 0.386 ENSMUST00000034988.3
ENSMUST00000179212.1
Rwdd2a

RWD domain containing 2A

chr9_-_67539392 0.373 ENSMUST00000039662.8
Tln2
talin 2
chr10_-_128409632 0.373 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
Nabp2




nucleic acid binding protein 2




chr8_-_124569696 0.367 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr15_-_53346118 0.366 ENSMUST00000077273.2
Ext1
exostoses (multiple) 1
chr8_+_70673364 0.362 ENSMUST00000146972.1
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_60046477 0.360 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
Pemt


phosphatidylethanolamine N-methyltransferase


chr10_-_78591945 0.355 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr12_-_100520778 0.351 ENSMUST00000062957.6
Ttc7b
tetratricopeptide repeat domain 7B
chr3_+_96576984 0.351 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr12_-_112671564 0.336 ENSMUST00000128300.2
Akt1
thymoma viral proto-oncogene 1
chr7_-_105399991 0.316 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr2_+_178193075 0.315 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr3_+_84925476 0.315 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr4_+_148602527 0.311 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr16_-_20426322 0.310 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr10_+_11609256 0.308 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr14_-_70627008 0.302 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr3_-_96293953 0.297 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr11_-_45955465 0.291 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr3_-_57294880 0.285 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr2_+_129100995 0.278 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chr9_+_38718263 0.271 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chrX_-_88760312 0.268 ENSMUST00000182943.1
Gm27000
predicted gene, 27000
chr16_-_35871544 0.267 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr10_-_18234930 0.263 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr7_+_28392916 0.262 ENSMUST00000003529.8
Paf1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr19_+_38481057 0.261 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr11_+_78536393 0.252 ENSMUST00000050366.8
ENSMUST00000108275.1
Ift20

intraflagellar transport 20

chr12_+_109544498 0.251 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr11_-_106579111 0.249 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chr8_+_70673198 0.248 ENSMUST00000034311.8
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_45955183 0.247 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr7_+_27591705 0.247 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr7_-_28392688 0.239 ENSMUST00000003536.8
Med29
mediator complex subunit 29
chr7_+_65693447 0.233 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr11_+_78536355 0.223 ENSMUST00000128788.1
Ift20
intraflagellar transport 20
chr16_-_91931643 0.217 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr16_-_20425881 0.216 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_95416850 0.215 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr7_+_24270420 0.211 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr2_-_127584668 0.204 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chrX_-_47892396 0.203 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr7_+_29768552 0.187 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr10_-_95417099 0.185 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr9_-_30922452 0.184 ENSMUST00000065112.6
Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr8_-_105326252 0.184 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr6_-_48048911 0.180 ENSMUST00000095944.3
Zfp777
zinc finger protein 777
chr6_+_29468068 0.174 ENSMUST00000143101.1
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr4_-_108032069 0.169 ENSMUST00000106709.2
Podn
podocan
chr7_-_100583072 0.167 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chrX_+_106015699 0.156 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr9_+_107296843 0.151 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr1_+_171213969 0.150 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3


nuclear receptor subfamily 1, group I, member 3


chr11_+_3488275 0.150 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr10_+_18235030 0.144 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chr18_+_42511496 0.131 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr13_-_46727932 0.131 ENSMUST00000021803.9
Nup153
nucleoporin 153
chr9_-_96719404 0.130 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr9_+_54538984 0.128 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr2_+_101886249 0.125 ENSMUST00000028584.7
Commd9
COMM domain containing 9
chr2_-_30093607 0.121 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_-_101425330 0.119 ENSMUST00000103102.3
Ptges3l
prostaglandin E synthase 3 (cytosolic)-like
chr3_+_97032416 0.106 ENSMUST00000132256.1
ENSMUST00000072600.6
Gja5

gap junction protein, alpha 5

chr4_+_120666562 0.097 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr4_-_140617062 0.091 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_-_159168642 0.076 ENSMUST00000077309.1
Gm4953
predicted pseudogene 4953
chr8_+_120736352 0.074 ENSMUST00000047737.3
ENSMUST00000162658.1
Irf8

interferon regulatory factor 8

chrX_-_8145679 0.073 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr3_+_142496924 0.073 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr8_+_86745679 0.069 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr19_-_59170978 0.066 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr5_-_140702241 0.065 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr2_-_155729359 0.064 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr11_+_53770014 0.050 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr8_+_111033890 0.046 ENSMUST00000034441.7
Aars
alanyl-tRNA synthetase
chr16_+_17508947 0.043 ENSMUST00000023444.3
Lztr1
leucine-zipper-like transcriptional regulator, 1
chr2_-_30093642 0.042 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_+_101425068 0.039 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr9_+_32224457 0.032 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr5_-_24445254 0.031 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr17_-_34187219 0.024 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr13_+_83738874 0.018 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr4_+_115088708 0.015 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chrX_-_8145713 0.014 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chrX_-_8252334 0.014 ENSMUST00000115595.1
ENSMUST00000033513.3
Ftsj1

FtsJ homolog 1 (E. coli)

chr11_-_78536235 0.014 ENSMUST00000017759.2
ENSMUST00000108277.2
Tnfaip1

tumor necrosis factor, alpha-induced protein 1 (endothelial)

chr5_-_24445166 0.014 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr17_+_34145231 0.004 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.6 2.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.5 1.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 1.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.4 1.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 3.9 GO:0097421 liver regeneration(GO:0097421)
0.3 2.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 0.8 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.3 1.8 GO:0015862 uridine transport(GO:0015862)
0.3 0.8 GO:0002314 germinal center B cell differentiation(GO:0002314) positive regulation of germinal center formation(GO:0002636) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) xanthine metabolic process(GO:0046110) purine deoxyribonucleoside metabolic process(GO:0046122) regulation of adenosine receptor signaling pathway(GO:0060167) negative regulation of mucus secretion(GO:0070256)
0.2 1.9 GO:0008343 adult feeding behavior(GO:0008343)
0.2 1.1 GO:2000427 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427)
0.2 1.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.5 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 0.6 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 1.3 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:1902022 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022)
0.1 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.3 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 3.2 GO:0034340 response to type I interferon(GO:0034340)
0.1 0.5 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.3 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.1 0.9 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 3.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.7 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.6 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.4 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.8 GO:0005796 Golgi lumen(GO:0005796)
0.4 2.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.4 1.1 GO:0044299 C-fiber(GO:0044299)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 1.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.0 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 0.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.2 GO:0090537 CERF complex(GO:0090537)
0.0 3.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 1.7 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.4 2.0 GO:0097643 amylin receptor activity(GO:0097643)
0.4 1.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.4 1.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 1.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 2.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 1.7 GO:0045545 syndecan binding(GO:0045545)
0.3 4.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 0.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 3.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.2 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.1 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0001846 opsonin binding(GO:0001846)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 0.6 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.1 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.4 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 1.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_RAS_PATHWAY Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.6 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.7 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 5.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 3.0 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 1.4 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 2.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins