Motif ID: Stat2

Z-value: 2.422


Transcription factors associated with Stat2:

Gene SymbolEntrez IDGene Name
Stat2 ENSMUSG00000040033.9 Stat2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat2mm10_v2_chr10_+_128270546_1282705770.076.6e-01Click!


Activity profile for motif Stat2.

activity profile for motif Stat2


Sorted Z-values histogram for motif Stat2

Sorted Z-values for motif Stat2



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_173942445 19.932 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr7_-_141010759 16.806 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr12_+_103434211 16.235 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr4_-_154636831 14.119 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr6_+_121245903 13.178 ENSMUST00000032198.9
Usp18
ubiquitin specific peptidase 18
chr3_-_107760221 13.014 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr1_-_156674290 12.439 ENSMUST00000079625.4
Tor3a
torsin family 3, member A
chr16_+_42907563 11.273 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr14_+_28511344 10.344 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr16_+_43363855 9.818 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr19_+_55741810 9.462 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr6_-_39118211 9.383 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr2_-_51972990 8.647 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr16_+_43235856 8.500 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_+_43364145 8.396 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr15_+_79892397 8.202 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr8_-_71537402 8.090 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr11_+_119393060 7.675 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr16_-_22439719 7.673 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr15_+_79892436 7.284 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr1_-_170110491 6.846 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr8_-_84773381 6.761 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr1_+_153751859 6.472 ENSMUST00000182538.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr1_+_153751946 6.393 ENSMUST00000183241.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr6_+_90550789 6.354 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr11_-_48871408 5.761 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr2_+_4559742 5.739 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr1_+_153749414 5.664 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr1_+_153749496 5.629 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr16_+_35938972 5.574 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr7_-_78578308 5.495 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr11_+_88999376 5.293 ENSMUST00000100627.2
ENSMUST00000107896.3
ENSMUST00000000284.6
Trim25


tripartite motif-containing 25


chr3_+_114030532 5.064 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr18_-_39490649 5.061 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr11_-_48871344 4.771 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr8_+_46739745 4.748 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr4_-_40239779 4.731 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr16_+_35938470 4.573 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr3_+_81932601 4.554 ENSMUST00000029649.2
Ctso
cathepsin O
chr18_+_69593361 4.490 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr18_+_61045139 4.473 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr19_+_36409719 4.194 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr2_+_122147680 4.107 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr9_-_58158498 3.876 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr9_+_118478344 3.836 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478182 3.629 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr3_+_60501252 3.577 ENSMUST00000099087.2
Mbnl1
muscleblind-like 1 (Drosophila)
chr5_+_114896936 3.572 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
Oasl2


2'-5' oligoadenylate synthetase-like 2


chr17_+_43389436 3.466 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr17_-_78882508 3.465 ENSMUST00000024884.4
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chrX_+_166238901 3.450 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chrX_+_41401128 3.443 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_+_23609895 3.388 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr16_+_26581704 3.334 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
Il1rap



interleukin 1 receptor accessory protein



chr4_-_156200818 3.330 ENSMUST00000085425.4
Isg15
ISG15 ubiquitin-like modifier
chr3_+_94954075 3.297 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
Rfx5





regulatory factor X, 5 (influences HLA class II expression)





chr7_-_25788635 3.280 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr5_+_107497762 3.263 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr9_-_58249660 3.199 ENSMUST00000124063.1
ENSMUST00000126690.1
Pml

promyelocytic leukemia

chr9_+_20868628 3.186 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr5_+_107497718 3.138 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr10_-_30655859 3.035 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr2_-_173276144 3.029 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr11_+_69846665 3.027 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr5_-_137116177 2.905 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr11_+_69846610 2.891 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr3_+_127791374 2.745 ENSMUST00000171621.1
Tifa
TRAF-interacting protein with forkhead-associated domain
chr7_+_78578830 2.734 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr6_+_86404336 2.729 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr13_-_23710714 2.720 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr3_-_137981523 2.716 ENSMUST00000136613.1
ENSMUST00000029806.6
Dapp1

dual adaptor for phosphotyrosine and 3-phosphoinositides 1

chr11_-_82991829 2.709 ENSMUST00000092840.4
ENSMUST00000038211.5
Slfn9

schlafen 9

chr4_+_138972885 2.701 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4


transmembrane and coiled-coil domains 4


chr2_-_36104060 2.656 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chrX_+_41401304 2.589 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_+_70459940 2.552 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr18_-_39489776 2.474 ENSMUST00000025300.6
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr4_-_40239700 2.445 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr13_+_14063776 2.426 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr10_+_40629987 2.375 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr9_+_96259246 2.374 ENSMUST00000179065.1
ENSMUST00000165768.2
Tfdp2

transcription factor Dp 2

chr11_-_118401826 2.325 ENSMUST00000106290.3
ENSMUST00000043722.3
Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr7_-_140955960 2.294 ENSMUST00000081649.8
Ifitm2
interferon induced transmembrane protein 2
chr7_+_44836286 2.212 ENSMUST00000033015.7
Il4i1
interleukin 4 induced 1
chr13_+_74639866 2.199 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr13_+_37345338 2.185 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr3_+_66981352 2.168 ENSMUST00000162036.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr1_-_165708088 2.162 ENSMUST00000040357.8
ENSMUST00000097474.3
Rcsd1

RCSD domain containing 1

chr14_+_14012491 2.153 ENSMUST00000022257.2
Atxn7
ataxin 7
chr17_+_33919332 2.139 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr13_+_15463837 2.130 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr11_+_58199556 1.932 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr18_+_37400845 1.925 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr4_+_42114817 1.915 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr2_-_156857946 1.901 ENSMUST00000099141.2
4930518I15Rik
RIKEN cDNA 4930518I15 gene
chr16_+_24393350 1.871 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_51934943 1.866 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr4_+_41903610 1.834 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr1_+_58505135 1.833 ENSMUST00000160947.1
ENSMUST00000129740.2
ENSMUST00000139825.1
Gm15834


predicted gene 15834


chr2_-_62646146 1.808 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr9_+_118040576 1.777 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chrX_+_109095359 1.745 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr9_-_58249702 1.737 ENSMUST00000135310.1
ENSMUST00000085673.4
ENSMUST00000114136.2
ENSMUST00000153820.1
ENSMUST00000124982.1
Pml




promyelocytic leukemia




chr1_+_167618246 1.717 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr11_+_72689997 1.672 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr13_+_49504774 1.666 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr4_+_94739276 1.650 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr9_+_92542223 1.591 ENSMUST00000070522.7
ENSMUST00000160359.1
Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chr16_-_24393588 1.565 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr17_+_29660595 1.564 ENSMUST00000024816.6
Cmtr1
cap methyltransferase 1
chr3_+_137671524 1.538 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr10_+_78069351 1.521 ENSMUST00000105393.1
Icosl
icos ligand
chr17_+_29660710 1.520 ENSMUST00000130423.1
Cmtr1
cap methyltransferase 1
chr9_+_118040509 1.505 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chr19_+_43752996 1.424 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr18_+_37725706 1.420 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr7_+_142460834 1.395 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr12_+_26469204 1.389 ENSMUST00000020969.3
Cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr9_+_118040475 1.384 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr17_+_86167777 1.382 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr14_-_79481268 1.331 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr8_+_31187317 1.328 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr13_-_103764502 1.314 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr18_-_39489880 1.260 ENSMUST00000152853.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr4_+_108834601 1.220 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr11_-_70459957 1.171 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr1_+_180942452 1.170 ENSMUST00000027800.8
Tmem63a
transmembrane protein 63a
chr2_-_51934644 1.166 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr16_-_10785525 1.147 ENSMUST00000038099.4
Socs1
suppressor of cytokine signaling 1
chr4_+_45972233 1.146 ENSMUST00000102929.1
Tdrd7
tudor domain containing 7
chr2_-_91649785 1.111 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr2_-_91649751 1.108 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chr7_-_46795881 1.098 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr11_-_47379405 1.059 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr3_+_142560052 1.033 ENSMUST00000106222.2
Gbp3
guanylate binding protein 3
chr3_+_142560108 1.030 ENSMUST00000128609.1
ENSMUST00000029935.7
Gbp3

guanylate binding protein 3

chr14_+_55578123 1.025 ENSMUST00000174484.1
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr11_-_49051122 1.025 ENSMUST00000132768.1
ENSMUST00000101295.2
ENSMUST00000093152.1
9930111J21Rik2


RIKEN cDNA 9930111J21 gene 2


chr10_+_13966268 0.987 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chrX_+_42150672 0.980 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr3_-_151749877 0.973 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr8_-_105938384 0.969 ENSMUST00000034369.8
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr12_-_79007276 0.952 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr14_+_55578360 0.937 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr1_+_175632169 0.930 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_52119438 0.919 ENSMUST00000070968.7
Stat1
signal transducer and activator of transcription 1
chr1_+_132008285 0.890 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr5_-_134229581 0.868 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
Ncf1


neutrophil cytosolic factor 1


chr12_+_90738201 0.865 ENSMUST00000181874.1
Gm26512
predicted gene, 26512
chr10_+_116301374 0.864 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr19_+_53329413 0.838 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr11_+_106751255 0.837 ENSMUST00000183111.1
ENSMUST00000106794.2
Milr1

mast cell immunoglobulin like receptor 1

chrX_+_42151002 0.804 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr11_+_106751226 0.801 ENSMUST00000147326.2
ENSMUST00000182896.1
ENSMUST00000182908.1
ENSMUST00000086353.4
Milr1



mast cell immunoglobulin like receptor 1



chr12_-_78980758 0.797 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr4_-_42773993 0.795 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr18_+_60212080 0.759 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chr3_+_142560351 0.749 ENSMUST00000106221.1
Gbp3
guanylate binding protein 3
chr7_+_107567445 0.725 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr11_+_31872100 0.718 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr2_+_167062934 0.696 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr10_+_39612934 0.664 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr16_+_8470763 0.654 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22


methyltransferase like 22


chr3_+_58525821 0.647 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr10_+_52358767 0.645 ENSMUST00000180473.1
Gm26741
predicted gene, 26741
chr2_-_167062981 0.626 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr16_-_35939082 0.586 ENSMUST00000081933.7
ENSMUST00000114885.1
Dtx3l

deltex 3-like (Drosophila)

chr19_-_29367294 0.565 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr3_+_19957037 0.561 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr9_-_117252450 0.559 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr19_+_7297658 0.556 ENSMUST00000170286.1
Gm17227
predicted gene 17227
chr6_+_112696772 0.548 ENSMUST00000180959.1
Gm26799
predicted gene, 26799
chr1_-_155972887 0.536 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr10_+_63061582 0.522 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr10_+_128225830 0.515 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chrX_-_38576166 0.501 ENSMUST00000050083.5
Cul4b
cullin 4B
chr2_-_77946331 0.468 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr9_+_19641224 0.467 ENSMUST00000079042.6
Zfp317
zinc finger protein 317
chr7_-_46795661 0.464 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr19_-_4477447 0.449 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr11_-_94242701 0.435 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr4_+_42255767 0.433 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr10_-_121586730 0.422 ENSMUST00000020316.2
Tbk1
TANK-binding kinase 1
chr11_+_29463735 0.414 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr11_-_116027961 0.401 ENSMUST00000106454.1
H3f3b
H3 histone, family 3B
chr4_-_132398199 0.399 ENSMUST00000136711.1
ENSMUST00000084249.4
Phactr4

phosphatase and actin regulator 4

chr2_-_105399286 0.393 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr10_-_99126321 0.376 ENSMUST00000060761.5
Phxr2
per-hexamer repeat gene 2
chrX_-_38576189 0.348 ENSMUST00000115118.1
Cul4b
cullin 4B
chr2_+_31572701 0.305 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3
chr2_-_77946375 0.276 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr7_-_102018139 0.273 ENSMUST00000094134.3
Il18bp
interleukin 18 binding protein
chr15_-_76243401 0.241 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr2_-_77946180 0.233 ENSMUST00000111824.1
ENSMUST00000111819.1
ENSMUST00000128963.1
Cwc22


CWC22 spliceosome-associated protein homolog (S. cerevisiae)


chr17_+_33955812 0.221 ENSMUST00000025178.9
ENSMUST00000114330.2
Vps52

vacuolar protein sorting 52 (yeast)

chr16_-_44139630 0.202 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr19_+_12460749 0.185 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr3_-_59262825 0.179 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr1_-_105356658 0.166 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr11_-_48992226 0.166 ENSMUST00000059930.2
ENSMUST00000068063.3
Gm12185
Tgtp1
predicted gene 12185
T cell specific GTPase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
3.6 17.8 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
3.1 12.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.9 8.6 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
2.6 15.5 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
2.1 6.4 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
2.0 8.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
1.9 11.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
1.8 5.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.8 9.0 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
1.8 14.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.8 8.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.7 6.8 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
1.6 13.2 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
1.6 4.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
1.5 7.7 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.5 53.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
1.5 4.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
1.3 5.1 GO:0044565 dendritic cell proliferation(GO:0044565)
1.2 9.5 GO:0048625 myoblast fate commitment(GO:0048625)
1.1 3.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.1 37.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 3.3 GO:0097350 neutrophil clearance(GO:0097350)
1.0 3.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.9 6.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.8 5.1 GO:0035989 tendon development(GO:0035989)
0.8 2.4 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.8 23.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.7 2.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.7 7.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.6 3.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.6 1.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 1.5 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.5 3.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.5 6.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.5 1.4 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.5 1.4 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.5 6.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 2.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 3.3 GO:0072602 interleukin-4 secretion(GO:0072602)
0.4 2.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.4 1.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 3.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 16.2 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.3 1.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.3 0.9 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.3 2.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 2.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 0.9 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.3 2.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 2.2 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.3 3.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 2.4 GO:0042118 endothelial cell activation(GO:0042118)
0.2 2.2 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.2 1.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 1.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 6.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.2 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 2.0 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.1 1.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.4 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 4.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 7.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.3 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.1 5.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.4 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.9 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 6.5 GO:0051607 defense response to virus(GO:0051607)
0.1 0.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 1.7 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.6 GO:0046688 response to copper ion(GO:0046688)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.7 GO:0002931 response to ischemia(GO:0002931)
0.0 1.3 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 2.6 GO:0007286 spermatid development(GO:0007286)
0.0 0.4 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.6 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.6 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.1 9.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.8 4.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.7 10.5 GO:0044754 autolysosome(GO:0044754)
0.7 6.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 2.0 GO:0008537 proteasome activator complex(GO:0008537)
0.4 6.0 GO:0043083 synaptic cleft(GO:0043083)
0.4 1.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 16.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.4 4.7 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.4 15.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 3.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 2.7 GO:0097165 nuclear stress granule(GO:0097165)
0.3 14.1 GO:0016235 aggresome(GO:0016235)
0.3 3.3 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.3 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 1.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 24.2 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.6 GO:0042629 mast cell granule(GO:0042629)
0.2 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.2 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.2 1.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 12.9 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 33.2 GO:0045177 apical part of cell(GO:0045177)
0.1 4.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 3.0 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.0 12.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 5.2 GO:0043235 receptor complex(GO:0043235)
0.0 2.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 18.2 GO:0005730 nucleolus(GO:0005730)
0.0 4.3 GO:0009986 cell surface(GO:0009986)
0.0 103.3 GO:0005634 nucleus(GO:0005634)
0.0 7.1 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
3.4 10.3 GO:0005110 frizzled-2 binding(GO:0005110)
2.2 8.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.1 6.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
1.1 4.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.1 5.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.9 19.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.9 4.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.9 3.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.9 6.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.8 3.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.8 6.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 2.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.7 8.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 16.2 GO:0005521 lamin binding(GO:0005521)
0.6 3.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.6 1.7 GO:0070052 collagen V binding(GO:0070052)
0.5 1.4 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.5 9.5 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.4 1.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.4 1.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.4 5.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.4 4.9 GO:0050897 cobalt ion binding(GO:0050897)
0.3 1.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 2.7 GO:0039706 co-receptor binding(GO:0039706)
0.3 1.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 24.2 GO:0019843 rRNA binding(GO:0019843)
0.3 5.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 57.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 2.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 3.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 3.3 GO:0031386 protein tag(GO:0031386)
0.2 12.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.2 21.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 2.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2 2.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 1.2 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2 3.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 3.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 13.0 GO:0008083 growth factor activity(GO:0008083)
0.1 12.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 2.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 2.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 6.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 4.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 6.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 3.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 20.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 13.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 8.6 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 13.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 10.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 13.4 PID_IL12_2PATHWAY IL12-mediated signaling events
0.3 2.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.3 7.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 18.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.2 11.6 PID_SHP2_PATHWAY SHP2 signaling
0.2 4.9 PID_MYC_PATHWAY C-MYC pathway
0.1 4.2 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.1 13.2 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 3.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 5.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 3.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.7 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 6.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 79.9 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
1.4 4.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.0 14.7 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 6.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 8.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 4.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 4.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 5.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.7 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 5.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.6 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.4 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 4.6 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 4.5 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME_TOLL_RECEPTOR_CASCADES Genes involved in Toll Receptor Cascades