Motif ID: Stat4_Stat3_Stat5b

Z-value: 0.728

Transcription factors associated with Stat4_Stat3_Stat5b:

Gene SymbolEntrez IDGene Name
Stat3 ENSMUSG00000004040.10 Stat3
Stat4 ENSMUSG00000062939.5 Stat4
Stat5b ENSMUSG00000020919.5 Stat5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat4mm10_v2_chr1_+_51987139_51987151-0.401.4e-02Click!
Stat3mm10_v2_chr11_-_100939457_1009394840.173.2e-01Click!
Stat5bmm10_v2_chr11_-_100850724_100850763-0.134.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Stat4_Stat3_Stat5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_80802789 4.766 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_-_64046925 2.502 ENSMUST00000107377.3
Tnc
tenascin C
chr7_-_78577771 2.147 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr17_+_26715644 2.021 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr5_+_88886809 1.956 ENSMUST00000148750.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr10_-_95416850 1.938 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr10_-_95417099 1.898 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr13_-_67755132 1.703 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr4_-_108031938 1.696 ENSMUST00000106708.1
Podn
podocan
chr7_+_141476374 1.692 ENSMUST00000117634.1
Tspan4
tetraspanin 4
chr13_-_67755192 1.586 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr4_-_108032069 1.564 ENSMUST00000106709.2
Podn
podocan
chr12_+_11265867 1.536 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr8_-_105568298 1.531 ENSMUST00000005849.5
Agrp
agouti related protein
chr4_+_148602527 1.528 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr5_-_34513892 1.504 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr10_+_128909866 1.452 ENSMUST00000026407.7
Cd63
CD63 antigen
chr3_-_107760221 1.422 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr16_-_23988852 1.405 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr8_+_25532125 1.362 ENSMUST00000167764.1
Fgfr1
fibroblast growth factor receptor 1
chr4_+_11704439 1.291 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr16_-_74411776 1.279 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr17_-_51826562 1.240 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr2_+_3424123 1.222 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr3_+_96576984 1.205 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr6_+_115134899 1.177 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr3_-_85741389 1.175 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr10_+_20312461 1.156 ENSMUST00000092678.3
ENSMUST00000043881.5
Bclaf1

BCL2-associated transcription factor 1

chr8_+_46739745 1.143 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr16_-_74411292 1.043 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr1_-_74124420 1.035 ENSMUST00000169786.1
Tns1
tensin 1
chr19_-_5797410 1.006 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr18_+_65873478 0.994 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr3_-_88000350 0.969 ENSMUST00000090971.5
Bcan
brevican
chr13_+_83738874 0.941 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr3_-_69004475 0.856 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr8_-_105326252 0.853 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr3_-_69004503 0.838 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr5_+_14025305 0.833 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chrX_-_95026671 0.818 ENSMUST00000096367.3
Spin4
spindlin family, member 4
chr10_+_13966268 0.815 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_28180226 0.813 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_28180272 0.806 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr3_+_33799791 0.796 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr1_-_135688094 0.781 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr1_-_155812859 0.781 ENSMUST00000035325.8
Qsox1
quiescin Q6 sulfhydryl oxidase 1
chr10_+_128303322 0.779 ENSMUST00000005825.6
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr11_-_101785252 0.763 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr11_-_117969176 0.756 ENSMUST00000054002.3
Socs3
suppressor of cytokine signaling 3
chr11_-_107915041 0.754 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr1_-_155812805 0.752 ENSMUST00000111764.2
Qsox1
quiescin Q6 sulfhydryl oxidase 1
chr4_-_140617062 0.748 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_+_128908907 0.748 ENSMUST00000105229.1
Cd63
CD63 antigen
chr3_-_69004565 0.740 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr14_-_55106547 0.736 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr1_+_136624901 0.734 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr3_-_51560816 0.724 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr2_-_77519565 0.716 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr15_-_96460838 0.716 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr16_+_91647859 0.705 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son



Son DNA binding protein



chr17_-_28350747 0.694 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr16_+_91372783 0.692 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr7_-_128461630 0.691 ENSMUST00000106226.2
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr7_-_128461168 0.687 ENSMUST00000106228.1
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr1_+_34005872 0.679 ENSMUST00000182296.1
Dst
dystonin
chrX_+_82948861 0.674 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr19_+_34550664 0.670 ENSMUST00000149829.1
ENSMUST00000102826.3
Ifit2

interferon-induced protein with tetratricopeptide repeats 2

chr14_+_70890099 0.657 ENSMUST00000022699.8
Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr16_+_92498122 0.656 ENSMUST00000023670.3
Clic6
chloride intracellular channel 6
chr7_-_128461313 0.646 ENSMUST00000165023.1
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr9_-_82975475 0.641 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr16_-_20730544 0.627 ENSMUST00000076422.5
Thpo
thrombopoietin
chr12_+_88953399 0.624 ENSMUST00000057634.7
Nrxn3
neurexin III
chr11_-_69695802 0.619 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr12_+_3426857 0.614 ENSMUST00000111215.3
ENSMUST00000092003.5
ENSMUST00000144247.2
ENSMUST00000153102.2
Asxl2



additional sex combs like 2 (Drosophila)



chr13_+_14063776 0.613 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr7_+_24112314 0.610 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr16_+_62854299 0.597 ENSMUST00000023629.8
Pros1
protein S (alpha)
chrX_-_134600976 0.588 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr11_-_72207413 0.587 ENSMUST00000108505.1
4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr9_+_38718263 0.582 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chr18_+_90510122 0.581 ENSMUST00000025515.6
Tmx3
thioredoxin-related transmembrane protein 3
chr4_-_126325672 0.579 ENSMUST00000102616.1
Tekt2
tektin 2
chr7_-_128461327 0.576 ENSMUST00000033135.7
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_+_130405256 0.574 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr15_-_89170688 0.568 ENSMUST00000060808.9
Plxnb2
plexin B2
chrX_+_139684980 0.553 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr10_-_54075730 0.551 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr2_+_25180737 0.550 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr1_-_64121389 0.550 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr11_+_78499087 0.543 ENSMUST00000017488.4
Vtn
vitronectin
chr17_-_43667015 0.541 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr8_+_120736352 0.539 ENSMUST00000047737.3
ENSMUST00000162658.1
Irf8

interferon regulatory factor 8

chr16_+_91372865 0.530 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr16_-_67620880 0.528 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr2_-_38287347 0.525 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr7_+_27233003 0.520 ENSMUST00000003860.6
ENSMUST00000108378.3
Adck4

aarF domain containing kinase 4

chr11_-_77787747 0.520 ENSMUST00000092883.2
Gm10277
predicted gene 10277
chr13_-_77135416 0.514 ENSMUST00000159462.1
ENSMUST00000151524.2
Ankrd32

ankyrin repeat domain 32

chr11_-_48871344 0.513 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr8_+_104831572 0.501 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr17_+_78508063 0.501 ENSMUST00000024880.9
Vit
vitrin
chr2_-_120970706 0.493 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr2_-_104257400 0.492 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr11_-_48871408 0.491 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr17_-_68004075 0.491 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr2_+_84734050 0.488 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr11_+_53519871 0.487 ENSMUST00000120878.2
Sept8
septin 8
chr13_+_112464070 0.485 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
Il6st


interleukin 6 signal transducer


chr19_+_38481057 0.483 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr18_+_42511496 0.479 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr11_+_53519920 0.479 ENSMUST00000147912.1
Sept8
septin 8
chr11_+_53519725 0.469 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr2_-_38287174 0.467 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr13_+_34002363 0.467 ENSMUST00000021844.8
Ripk1
receptor (TNFRSF)-interacting serine-threonine kinase 1
chr17_-_28350600 0.465 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr3_+_94693556 0.461 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr16_-_20426322 0.461 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr7_+_120917744 0.452 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr7_+_27591705 0.451 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr12_+_85473883 0.451 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr10_+_69925800 0.441 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr5_+_123015010 0.440 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr2_-_132578155 0.438 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr17_-_57247632 0.434 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr12_-_64965496 0.434 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr9_-_103230415 0.433 ENSMUST00000035158.9
Trf
transferrin
chr18_-_23041641 0.430 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr7_+_120843551 0.430 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr3_+_69004711 0.427 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr16_-_67620805 0.424 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr5_-_86172747 0.424 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr6_+_34598530 0.424 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr13_-_41847626 0.423 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr16_-_20426375 0.419 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr13_-_41847482 0.419 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr11_-_98729374 0.418 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr2_-_132578244 0.417 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr1_+_104768510 0.417 ENSMUST00000062528.8
Cdh20
cadherin 20
chr11_+_49203285 0.411 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr6_+_34598500 0.410 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr12_+_82616885 0.407 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr10_+_69925766 0.405 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chrX_+_71215006 0.403 ENSMUST00000101501.3
ENSMUST00000061970.5
ENSMUST00000025391.4
ENSMUST00000114621.1
ENSMUST00000033700.5
Mtm1




X-linked myotubular myopathy gene 1




chr19_-_47050823 0.401 ENSMUST00000026032.5
Pcgf6
polycomb group ring finger 6
chr6_+_149309391 0.400 ENSMUST00000130664.1
ENSMUST00000046689.6
2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr6_-_5496296 0.397 ENSMUST00000019721.4
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr11_+_49203465 0.395 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr7_+_127800604 0.391 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr6_+_149309444 0.389 ENSMUST00000100765.4
2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr7_-_24208093 0.385 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr4_+_118428078 0.384 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chrX_-_160994665 0.383 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr2_+_5951440 0.382 ENSMUST00000060092.6
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr15_+_64817694 0.382 ENSMUST00000180105.1
Gm21798
predicted gene, 21798
chr3_-_127780461 0.380 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr7_+_29768552 0.374 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr4_-_15149051 0.374 ENSMUST00000041606.7
Necab1
N-terminal EF-hand calcium binding protein 1
chrX_-_8145679 0.372 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr14_+_76504478 0.372 ENSMUST00000022587.9
ENSMUST00000134109.1
Tsc22d1

TSC22 domain family, member 1

chr17_-_78985428 0.371 ENSMUST00000118991.1
Prkd3
protein kinase D3
chr9_+_20868628 0.370 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr7_+_44896125 0.368 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr3_-_90490975 0.367 ENSMUST00000149884.1
Snapin
SNAP-associated protein
chr3_-_108210438 0.365 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr7_+_27591513 0.364 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr10_-_127288999 0.364 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr4_+_136310991 0.361 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr5_+_76588663 0.360 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr4_+_136310952 0.358 ENSMUST00000105850.1
ENSMUST00000148843.3
Hnrnpr

heterogeneous nuclear ribonucleoprotein R

chr19_-_29047847 0.354 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr7_+_28179469 0.353 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr15_+_6708372 0.351 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chrX_-_8145713 0.350 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr10_-_54075702 0.349 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr14_+_56668242 0.348 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr10_+_40349265 0.347 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr13_+_96542727 0.345 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr7_+_30095150 0.345 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr2_-_140170528 0.343 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr12_+_64965742 0.342 ENSMUST00000066296.7
Fam179b
family with sequence similarity 179, member B
chr11_+_101245996 0.342 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr1_-_155146755 0.341 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr10_-_120112946 0.340 ENSMUST00000020449.5
Helb
helicase (DNA) B
chr1_-_130729249 0.340 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr9_+_59750876 0.339 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr11_+_23306910 0.339 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr13_-_85288999 0.337 ENSMUST00000109552.2
Rasa1
RAS p21 protein activator 1
chr5_-_100500592 0.336 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr4_+_136310936 0.330 ENSMUST00000131671.1
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr7_+_24134148 0.328 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr17_+_45433823 0.327 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr9_+_57130690 0.327 ENSMUST00000160147.1
ENSMUST00000161663.1
ENSMUST00000034836.9
ENSMUST00000161182.1
Man2c1



mannosidase, alpha, class 2C, member 1



chr16_-_20425881 0.323 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr18_+_37320374 0.322 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr10_-_95415283 0.320 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr14_+_76504185 0.319 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr17_+_34145231 0.319 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr13_+_96542602 0.318 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr8_-_124569696 0.317 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.7 2.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.6 2.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.5 1.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.5 1.4 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.5 1.4 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.4 2.2 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 2.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 1.0 GO:0061744 motor behavior(GO:0061744) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 2.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 0.3 GO:0016568 chromatin modification(GO:0016568)
0.3 1.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.3 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 1.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 1.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 2.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 4.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 1.5 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.6 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.2 0.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 0.5 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.2 1.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 1.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.1 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.8 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.6 GO:1903012 positive regulation of bone development(GO:1903012)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.1 3.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 2.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.7 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.1 0.3 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.6 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.3 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.6 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 1.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.6 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.4 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:1905076 regulation of interleukin-17 secretion(GO:1905076)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.3 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.2 GO:0017145 stem cell division(GO:0017145)
0.0 0.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.1 GO:0048266 response to pain(GO:0048265) behavioral response to pain(GO:0048266)
0.0 0.3 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 2.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) regulation of response to drug(GO:2001023)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.7 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.2 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.3 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.4 GO:0031100 organ regeneration(GO:0031100)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.4 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:2000481 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0031960 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.4 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.2 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 1.5 GO:0035061 interchromatin granule(GO:0035061)
0.5 1.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 2.1 GO:0005796 Golgi lumen(GO:0005796)
0.3 0.8 GO:0031251 PAN complex(GO:0031251)
0.2 4.8 GO:0032279 asymmetric synapse(GO:0032279)
0.2 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.2 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0090537 CERF complex(GO:0090537)
0.1 1.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 2.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 1.0 GO:0044754 autolysosome(GO:0044754)
0.1 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.1 GO:0043194 axon initial segment(GO:0043194)
0.1 0.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.5 GO:0097342 death-inducing signaling complex(GO:0031264) ripoptosome(GO:0097342)
0.1 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.0 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
0.0 0.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 3.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897) clathrin complex(GO:0071439)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0034704 calcium channel complex(GO:0034704)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.8 4.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 2.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 2.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.4 2.5 GO:0045545 syndecan binding(GO:0045545)
0.3 1.2 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.3 2.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 0.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.2 0.9 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 0.4 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.1 0.4 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 1.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 2.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.4 GO:0001846 opsonin binding(GO:0001846)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:0050733 RS domain binding(GO:0050733)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.1 2.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.2 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 0.3 GO:0002135 CTP binding(GO:0002135)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0004518 nuclease activity(GO:0004518)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 3.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.6 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.8 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.8 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.2 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.6 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.3 1.6 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 4.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 2.0 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.4 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.5 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 2.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.3 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.2 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.6 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.1 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.2 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.0 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 1.5 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 1.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 2.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 1.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions