Motif ID: Stat6

Z-value: 0.564


Transcription factors associated with Stat6:

Gene SymbolEntrez IDGene Name
Stat6 ENSMUSG00000002147.12 Stat6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat6mm10_v2_chr10_+_127642975_127643034-0.334.6e-02Click!


Activity profile for motif Stat6.

activity profile for motif Stat6


Sorted Z-values histogram for motif Stat6

Sorted Z-values for motif Stat6



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 4.522 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr14_-_21989475 4.330 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr3_+_102010138 3.661 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr5_-_106574706 3.468 ENSMUST00000131029.1
ENSMUST00000124394.2
RP24-421H18.1

RP24-421H18.1

chr18_+_50053282 3.349 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr9_-_70421533 3.272 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr2_-_113848655 3.207 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr4_+_116708467 2.978 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr2_-_113848601 2.967 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr3_-_86548268 2.869 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr17_+_29090969 2.696 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr4_+_116708571 2.491 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr4_+_116708687 2.303 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr17_-_89910449 2.110 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr4_+_116708624 2.105 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr7_-_70366735 2.034 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr11_-_102579461 1.786 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr1_+_146497614 1.612 ENSMUST00000132847.1
ENSMUST00000166814.1
Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr15_-_82244716 1.402 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr1_+_146495621 1.323 ENSMUST00000074622.4
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr8_+_45507768 1.157 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr7_-_126800354 1.137 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr6_-_4086914 1.019 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr5_+_114786045 0.979 ENSMUST00000137519.1
Ankrd13a
ankyrin repeat domain 13a
chr2_+_163225363 0.917 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr11_-_60220550 0.881 ENSMUST00000020846.1
Srebf1
sterol regulatory element binding transcription factor 1
chr1_+_134182150 0.849 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr2_-_101628930 0.848 ENSMUST00000099682.2
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr2_+_29346803 0.848 ENSMUST00000028139.4
ENSMUST00000113830.4
Med27

mediator complex subunit 27

chr7_-_126800036 0.833 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr1_+_134182404 0.817 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chrX_-_53269786 0.816 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr1_-_120121030 0.787 ENSMUST00000027634.6
Dbi
diazepam binding inhibitor
chr14_+_75845093 0.780 ENSMUST00000110894.2
Tpt1
tumor protein, translationally-controlled 1
chr16_-_23890805 0.773 ENSMUST00000004480.3
Sst
somatostatin
chr1_+_88227005 0.771 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr12_-_87233556 0.755 ENSMUST00000021423.7
Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr1_-_144177259 0.753 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr1_-_125912160 0.750 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr2_+_30077684 0.733 ENSMUST00000125346.1
Pkn3
protein kinase N3
chr15_+_25773985 0.729 ENSMUST00000125667.1
Myo10
myosin X
chr15_+_59648350 0.685 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr7_+_126766397 0.678 ENSMUST00000032944.7
Gdpd3
glycerophosphodiester phosphodiesterase domain containing 3
chr19_-_50030735 0.667 ENSMUST00000071866.1
Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr2_-_101628958 0.664 ENSMUST00000111231.3
B230118H07Rik
RIKEN cDNA B230118H07 gene
chrX_-_140956675 0.605 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr5_-_88675190 0.605 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr4_-_43454582 0.601 ENSMUST00000107925.1
Cd72
CD72 antigen
chr12_-_15816762 0.598 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr4_-_43454563 0.569 ENSMUST00000107926.1
Cd72
CD72 antigen
chr1_-_125913101 0.565 ENSMUST00000161361.1
Lypd1
Ly6/Plaur domain containing 1
chr2_-_73453918 0.563 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr4_-_117125618 0.555 ENSMUST00000183310.1
Btbd19
BTB (POZ) domain containing 19
chr8_-_105758570 0.551 ENSMUST00000155038.2
ENSMUST00000013294.9
Gfod2

glucose-fructose oxidoreductase domain containing 2

chr11_+_108587077 0.548 ENSMUST00000146912.2
Cep112
centrosomal protein 112
chrX_-_103186618 0.490 ENSMUST00000121720.1
Nap1l2
nucleosome assembly protein 1-like 2
chr7_-_127286385 0.480 ENSMUST00000172206.2
Gm17511
predicted gene, 17511
chr10_+_43901782 0.450 ENSMUST00000054418.5
Rtn4ip1
reticulon 4 interacting protein 1
chrX_-_140543177 0.447 ENSMUST00000055738.5
Tsc22d3
TSC22 domain family, member 3
chr19_+_46623387 0.441 ENSMUST00000111855.4
Wbp1l
WW domain binding protein 1 like
chr1_+_156035392 0.436 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr7_-_38227975 0.428 ENSMUST00000098513.4
Plekhf1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr7_-_44816586 0.424 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr3_+_97032416 0.423 ENSMUST00000132256.1
ENSMUST00000072600.6
Gja5

gap junction protein, alpha 5

chr2_+_118900377 0.420 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr16_-_22265950 0.419 ENSMUST00000161286.1
Tra2b
transformer 2 beta homolog (Drosophila)
chr16_-_56712825 0.415 ENSMUST00000136394.1
Tfg
Trk-fused gene
chr1_-_51915901 0.411 ENSMUST00000018561.7
ENSMUST00000114537.2
Myo1b

myosin IB

chr13_+_99100698 0.405 ENSMUST00000181742.1
Gm807
predicted gene 807
chr2_-_14056029 0.404 ENSMUST00000074854.7
Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr4_-_116708312 0.403 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr19_+_12846773 0.397 ENSMUST00000164001.1
Gm5244
predicted pseudogene 5244
chr2_-_14055963 0.370 ENSMUST00000091429.5
ENSMUST00000114753.1
Ptpla

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

chr10_-_128626464 0.343 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr1_+_173673651 0.327 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr13_-_115090123 0.320 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chrX_+_134756563 0.318 ENSMUST00000081834.3
ENSMUST00000086880.4
ENSMUST00000086884.4
Armcx3


armadillo repeat containing, X-linked 3


chr14_+_20703027 0.318 ENSMUST00000071215.3
Chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr11_-_3914664 0.317 ENSMUST00000109995.1
ENSMUST00000051207.1
Slc35e4

solute carrier family 35, member E4

chr9_-_119093468 0.308 ENSMUST00000010804.2
Plcd1
phospholipase C, delta 1
chr9_-_35176039 0.302 ENSMUST00000119847.1
ENSMUST00000034539.5
Dcps

decapping enzyme, scavenger

chr1_+_156035705 0.295 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr8_-_106573461 0.283 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr6_-_125313844 0.275 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr19_-_33761949 0.249 ENSMUST00000025694.6
ENSMUST00000147153.1
Lipo1
Lipo2
lipase, member O1
lipase, member O2
chr7_+_28350652 0.245 ENSMUST00000082134.4
Rps16
ribosomal protein S16
chr15_-_33405976 0.244 ENSMUST00000079057.6
1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr10_-_78591945 0.238 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_+_104775911 0.227 ENSMUST00000055593.7
Gm8258
predicted gene 8258
chr2_-_125858985 0.225 ENSMUST00000110462.1
Cops2
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
chr2_-_30093642 0.217 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr14_-_55758458 0.211 ENSMUST00000001497.7
Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr19_-_7295394 0.205 ENSMUST00000025921.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr9_+_75037809 0.203 ENSMUST00000167885.1
Arpp19
cAMP-regulated phosphoprotein 19
chr18_+_24205937 0.194 ENSMUST00000164998.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr17_-_34187219 0.194 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr11_-_11890394 0.179 ENSMUST00000109659.2
Ddc
dopa decarboxylase
chr18_+_3383223 0.176 ENSMUST00000162301.1
ENSMUST00000161317.1
Cul2

cullin 2

chr17_+_28232723 0.172 ENSMUST00000002320.8
Ppard
peroxisome proliferator activator receptor delta
chr2_-_147186389 0.165 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr3_+_14641722 0.165 ENSMUST00000029071.8
Car13
carbonic anhydrase 13
chrX_+_163911401 0.151 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr3_-_8923796 0.150 ENSMUST00000042148.5
Mrps28
mitochondrial ribosomal protein S28
chr14_-_20702991 0.145 ENSMUST00000180987.1
6230400D17Rik
RIKEN cDNA 6230400D17 gene
chr12_+_37108533 0.144 ENSMUST00000041183.5
Meox2
mesenchyme homeobox 2
chr5_-_24445166 0.142 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chrX_+_7841800 0.138 ENSMUST00000033494.9
ENSMUST00000115666.1
Otud5

OTU domain containing 5

chr11_-_78183551 0.136 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chr14_+_79587691 0.126 ENSMUST00000054908.8
Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr11_-_11890368 0.122 ENSMUST00000155690.1
Ddc
dopa decarboxylase
chr9_+_120929216 0.116 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chrX_+_7842056 0.115 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
Otud5


OTU domain containing 5


chr11_+_3650253 0.114 ENSMUST00000096441.3
Morc2a
microrchidia 2A
chr9_+_109054903 0.114 ENSMUST00000151141.1
ENSMUST00000152771.1
Shisa5

shisa homolog 5 (Xenopus laevis)

chr6_+_136954521 0.112 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr1_-_175625580 0.112 ENSMUST00000027810.7
Fh1
fumarate hydratase 1
chr11_+_75532099 0.111 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr10_-_19015347 0.108 ENSMUST00000019997.4
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr2_-_30093607 0.105 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr19_+_10842531 0.105 ENSMUST00000025646.2
Slc15a3
solute carrier family 15, member 3
chr13_-_23683941 0.098 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr5_-_24445254 0.097 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr11_+_75532127 0.092 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr12_-_57197311 0.076 ENSMUST00000044634.5
Slc25a21
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
chr15_+_98632220 0.075 ENSMUST00000109150.1
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr1_-_44118757 0.074 ENSMUST00000027213.7
ENSMUST00000065767.2
Kdelc1

KDEL (Lys-Asp-Glu-Leu) containing 1

chr8_-_47990535 0.072 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr1_+_161142706 0.067 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr9_+_75051977 0.067 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr9_+_75037838 0.063 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr6_+_66896397 0.061 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr7_+_140882430 0.057 ENSMUST00000164681.1
ENSMUST00000163610.1
Psmd13

proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

chr6_+_66896480 0.054 ENSMUST00000114222.1
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr6_+_38381469 0.053 ENSMUST00000162554.1
ENSMUST00000161751.1
Ttc26

tetratricopeptide repeat domain 26

chr9_+_75037744 0.049 ENSMUST00000168301.1
Arpp19
cAMP-regulated phosphoprotein 19
chr6_-_71440623 0.033 ENSMUST00000002292.8
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_-_51972990 0.031 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr2_+_126707319 0.030 ENSMUST00000028841.7
ENSMUST00000110416.2
Usp8

ubiquitin specific peptidase 8

chr18_+_3382979 0.023 ENSMUST00000025073.5
Cul2
cullin 2
chr8_-_105701077 0.022 ENSMUST00000042608.6
Acd
adrenocortical dysplasia
chr6_+_48647224 0.022 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr18_-_36726730 0.020 ENSMUST00000061829.6
Cd14
CD14 antigen
chr2_+_70562854 0.019 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr13_-_14063395 0.016 ENSMUST00000170957.1
Ggps1
geranylgeranyl diphosphate synthase 1
chr2_-_144550777 0.006 ENSMUST00000028915.5
Rbbp9
retinoblastoma binding protein 9
chr9_+_109054839 0.002 ENSMUST00000154184.1
Shisa5
shisa homolog 5 (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.6 4.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 2.0 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 2.7 GO:0071493 cellular response to UV-B(GO:0071493)
0.2 0.7 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 2.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 0.8 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 0.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.4 GO:0086053 renin secretion into blood stream(GO:0002001) cell communication by chemical coupling(GO:0010643) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) regulation of renin secretion into blood stream(GO:1900133)
0.1 3.7 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 2.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.9 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.3 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 3.3 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.7 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 2.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 3.3 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 1.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0071220 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 0.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 1.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 3.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 3.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.2 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 5.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.9 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.6 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.0 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 3.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 6.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling