Motif ID: Taf1

Z-value: 3.203


Transcription factors associated with Taf1:

Gene SymbolEntrez IDGene Name
Taf1 ENSMUSG00000031314.11 Taf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Taf1mm10_v2_chrX_+_101532734_1015327770.764.6e-08Click!


Activity profile for motif Taf1.

activity profile for motif Taf1


Sorted Z-values histogram for motif Taf1

Sorted Z-values for motif Taf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Taf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_119047116 14.156 ENSMUST00000152380.1
ENSMUST00000099542.2
 Casc5

cancer susceptibility candidate 5

chr10_+_79854618 13.734 ENSMUST00000165704.1
 Ptbp1
polypyrimidine tract binding protein 1
chr10_+_79854658 12.859 ENSMUST00000171599.1
ENSMUST00000095457.4
 Ptbp1

polypyrimidine tract binding protein 1

chr3_+_69004969 11.821 ENSMUST00000136502.1
ENSMUST00000107803.1
 Smc4

structural maintenance of chromosomes 4

chr2_+_119047129 11.742 ENSMUST00000153300.1
ENSMUST00000028799.5
 Casc5

cancer susceptibility candidate 5

chr3_+_69004711 11.348 ENSMUST00000042901.8
 Smc4
structural maintenance of chromosomes 4
chr5_-_123749393 10.037 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
 Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 9.669 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
 Rsrc2


arginine/serine-rich coiled-coil 2


chr7_+_59228743 9.345 ENSMUST00000107537.1
 Ube3a
ubiquitin protein ligase E3A
chr3_-_84220853 8.384 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
 Trim2


tripartite motif-containing 2


chr6_+_38433913 8.304 ENSMUST00000160583.1
 Ubn2
ubinuclein 2
chr15_-_86033777 8.052 ENSMUST00000016172.7
 Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr5_+_23434435 7.455 ENSMUST00000094962.2
ENSMUST00000115128.1
 Kmt2e

lysine (K)-specific methyltransferase 2E

chr9_-_72491939 7.317 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
 Tex9




testis expressed gene 9




chr9_+_122951051 6.972 ENSMUST00000040717.5
 Kif15
kinesin family member 15
chr12_-_46818749 6.950 ENSMUST00000021438.6
 Nova1
neuro-oncological ventral antigen 1
chr2_+_119618717 6.918 ENSMUST00000028771.7
 Nusap1
nucleolar and spindle associated protein 1
chr12_-_101083653 6.913 ENSMUST00000048305.8
ENSMUST00000163095.1
 Smek1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

chr4_+_148039035 6.705 ENSMUST00000097788.4
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr9_+_80067452 6.635 ENSMUST00000165607.2
 Senp6
SUMO/sentrin specific peptidase 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 447 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 29.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
2.9 23.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.6 17.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 14.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2 14.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
3.6 14.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 14.0 GO:0008380 RNA splicing(GO:0008380)
2.6 13.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.8 11.5 GO:0060009 Sertoli cell development(GO:0060009)
1.4 10.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.5 10.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.5 10.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
2.1 10.5 GO:0034421 post-translational protein acetylation(GO:0034421)
2.1 10.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
1.0 9.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.9 9.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
2.3 9.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 9.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
1.1 8.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
2.2 8.7 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 220 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 33.3 GO:0005654 nucleoplasm(GO:0005654)
2.3 23.2 GO:0000796 condensin complex(GO:0000796)
0.0 18.1 GO:0016604 nuclear body(GO:0016604)
0.5 16.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 14.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 13.6 GO:0000790 nuclear chromatin(GO:0000790)
0.2 12.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 12.3 GO:0000785 chromatin(GO:0000785)
4.0 11.9 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.6 11.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 11.8 GO:0005815 microtubule organizing center(GO:0005815)
1.9 11.2 GO:0098536 deuterosome(GO:0098536)
0.5 10.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 9.7 GO:0000793 condensed chromosome(GO:0000793)
0.1 9.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.5 9.3 GO:0097431 mitotic spindle pole(GO:0097431)
2.1 8.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
1.7 8.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 8.4 GO:0000922 spindle pole(GO:0000922)
0.0 8.4 GO:0044306 neuron projection terminus(GO:0044306)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 257 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 56.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 41.6 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 31.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
4.7 28.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 21.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 19.7 GO:0003777 microtubule motor activity(GO:0003777)
0.2 15.6 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.2 15.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 15.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 14.4 GO:0008017 microtubule binding(GO:0008017)
1.9 13.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 13.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 12.9 GO:0008270 zinc ion binding(GO:0008270)
3.0 11.9 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
3.8 11.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 11.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 10.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.4 10.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.8 10.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.5 10.3 GO:0099609 microtubule lateral binding(GO:0099609)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 42.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.4 25.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.2 14.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 13.2 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.3 12.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.3 11.5 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.3 11.1 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.3 10.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 9.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 8.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.6 8.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 7.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 7.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.3 6.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 6.0 PID_ATM_PATHWAY ATM pathway
0.3 5.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.4 4.9 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 4.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 4.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 4.0 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 36.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.9 25.6 REACTOME_KINESINS Genes involved in Kinesins
0.2 22.9 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.4 21.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
1.1 18.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.6 17.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.4 16.3 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.4 13.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.3 11.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 8.3 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 7.7 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.3 7.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 6.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 6.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 6.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 5.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.2 5.8 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 5.8 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.1 5.7 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 5.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs