Motif ID: Tal1

Z-value: 0.696


Transcription factors associated with Tal1:

Gene SymbolEntrez IDGene Name
Tal1 ENSMUSG00000028717.6 Tal1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tal1mm10_v2_chr4_+_115057410_115057438-0.183.0e-01Click!


Activity profile for motif Tal1.

activity profile for motif Tal1


Sorted Z-values histogram for motif Tal1

Sorted Z-values for motif Tal1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tal1

PNG image of the network

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Top targets:


Showing 1 to 20 of 159 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 7.163 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr11_+_32276400 3.712 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 3.523 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr2_+_180499893 2.742 ENSMUST00000029084.2
 Ntsr1
neurotensin receptor 1
chr8_-_125898291 1.764 ENSMUST00000047239.6
 Pcnxl2
pecanex-like 2 (Drosophila)
chr16_-_18621366 1.692 ENSMUST00000051160.2
 Gp1bb
glycoprotein Ib, beta polypeptide
chr8_-_71511762 1.670 ENSMUST00000048452.4
 Plvap
plasmalemma vesicle associated protein
chr6_-_72235559 1.552 ENSMUST00000042646.7
 Atoh8
atonal homolog 8 (Drosophila)
chr8_-_77517898 1.549 ENSMUST00000076316.4
 Arhgap10
Rho GTPase activating protein 10
chr12_+_95692212 1.518 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_+_169969409 1.508 ENSMUST00000180638.1
 3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr10_-_11082287 1.460 ENSMUST00000105561.2
ENSMUST00000044306.6
 Grm1

glutamate receptor, metabotropic 1

chr9_+_57998036 1.448 ENSMUST00000181289.1
 Gm17322
predicted gene, 17322
chr5_-_5265224 1.444 ENSMUST00000115450.1
 Cdk14
cyclin-dependent kinase 14
chr5_-_107972864 1.332 ENSMUST00000153172.1
 Fam69a
family with sequence similarity 69, member A
chr19_+_42247544 1.327 ENSMUST00000122375.1
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr11_+_78115565 1.301 ENSMUST00000155571.1
 Fam222b
family with sequence similarity 222, member B
chr7_+_119900099 1.258 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr6_-_126645784 1.223 ENSMUST00000055168.3
 Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr10_+_116177351 1.167 ENSMUST00000155606.1
ENSMUST00000128399.1
 Ptprr

protein tyrosine phosphatase, receptor type, R


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 14.4 GO:0015671 oxygen transport(GO:0015671)
0.7 2.7 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 1.7 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 1.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 1.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 1.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4 1.2 GO:0050975 sensory perception of touch(GO:0050975)
0.3 1.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.4 1.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202) positive regulation of execution phase of apoptosis(GO:1900119)
0.2 1.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 1.0 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 0.9 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.9 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:0046549 retinal cone cell development(GO:0046549)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 14.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 3.6 GO:0005901 caveola(GO:0005901)
0.7 2.7 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.5 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.3 1.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.4 GO:0071437 invadopodium(GO:0071437)
0.1 1.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 0.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.2 0.7 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 14.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.4 1.5 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.3 1.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 0.9 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.8 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 1.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 1.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.5 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.8 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 0.7 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC