Motif ID: Tbx19

Z-value: 0.791


Transcription factors associated with Tbx19:

Gene SymbolEntrez IDGene Name
Tbx19 ENSMUSG00000026572.5 Tbx19



Activity profile for motif Tbx19.

activity profile for motif Tbx19


Sorted Z-values histogram for motif Tbx19

Sorted Z-values for motif Tbx19



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx19

PNG image of the network

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Top targets:


Showing 1 to 20 of 104 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_82406777 4.024 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr11_+_101468164 3.849 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr2_-_113758638 3.547 ENSMUST00000099575.3
 Grem1
gremlin 1
chr3_+_94693556 2.737 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
 Selenbp2



selenium binding protein 2



chr7_+_130936172 2.478 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr7_-_132776855 2.247 ENSMUST00000106168.1
 Fam53b
family with sequence similarity 53, member B
chr2_+_179442427 2.191 ENSMUST00000000314.6
 Cdh4
cadherin 4
chr9_+_15520830 2.138 ENSMUST00000178999.1
 Smco4
single-pass membrane protein with coiled-coil domains 4
chr17_+_6978860 2.098 ENSMUST00000089119.5
ENSMUST00000179728.1
 Rnaset2b

ribonuclease T2B

chr6_-_54593139 1.895 ENSMUST00000046520.6
 Fkbp14
FK506 binding protein 14
chr9_-_21760275 1.829 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_-_132786914 1.753 ENSMUST00000065371.7
ENSMUST00000106166.1
 Fam53b

family with sequence similarity 53, member B

chrY_+_897782 1.507 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr14_-_66124482 1.447 ENSMUST00000070515.1
 Ephx2
epoxide hydrolase 2, cytoplasmic
chr11_-_101171302 1.430 ENSMUST00000164474.1
ENSMUST00000043397.7
 Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr2_+_175010241 1.342 ENSMUST00000109069.1
ENSMUST00000109070.2
 Gm14444

predicted gene 14444

chrM_+_9870 1.240 ENSMUST00000084013.1
 mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr2_-_175067763 1.196 ENSMUST00000072895.3
ENSMUST00000109066.1
 Gm14393

predicted gene 14393

chr13_-_21453714 1.173 ENSMUST00000032820.7
ENSMUST00000110485.1
 Zscan26

zinc finger and SCAN domain containing 26

chr1_-_24612700 1.159 ENSMUST00000088336.1
 Gm10222
predicted gene 10222

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 4.8 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.1 4.0 GO:0035411 catenin import into nucleus(GO:0035411)
0.3 3.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.2 3.5 GO:1901228 regulation of osteoclast proliferation(GO:0090289) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) negative regulation of bone development(GO:1903011)
0.4 2.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 1.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 1.4 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.2 1.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 1.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 1.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.9 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.8 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 2.4 GO:0070469 respiratory chain(GO:0070469)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 1.8 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785) dense body(GO:0097433)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.1 0.5 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 4.8 GO:0004966 galanin receptor activity(GO:0004966)
0.4 3.5 GO:0036122 BMP binding(GO:0036122)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)
0.2 2.7 GO:0008430 selenium binding(GO:0008430)
0.1 2.6 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 2.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.1 GO:0004540 ribonuclease activity(GO:0004540)
0.2 1.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 1.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0015091 signal recognition particle binding(GO:0005047) ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation