---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_26229707	19.326	ENSMUST00000060716.5 ENSMUST00000164660.1	Samd3	sterile alpha motif domain containing 3
chr1_+_6730051	14.145	ENSMUST00000043578.6 ENSMUST00000131467.1 ENSMUST00000150761.1 ENSMUST00000151281.1	St18	suppression of tumorigenicity 18
chr1_-_138847579	11.575	ENSMUST00000093486.3 ENSMUST00000046870.6	Lhx9	LIM homeobox protein 9
chr2_-_13011747	10.278	ENSMUST00000061545.5	C1ql3	C1q-like 3
chr1_+_6730135	8.695	ENSMUST00000155921.1	St18	suppression of tumorigenicity 18
chr6_+_15196949	8.449	ENSMUST00000151301.1 ENSMUST00000131414.1 ENSMUST00000140557.1 ENSMUST00000115469.1	Foxp2	forkhead box P2
chr7_-_28302238	7.758	ENSMUST00000108315.3	Dll3	delta-like 3 (Drosophila)
chr1_+_132316112	5.737	ENSMUST00000082125.5 ENSMUST00000072177.7	Nuak2	NUAK family, SNF1-like kinase, 2
chr11_-_84068357	5.500	ENSMUST00000100705.4	Dusp14	dual specificity phosphatase 14
chr17_+_29093763	5.360	ENSMUST00000023829.6	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)
chr11_-_84068766	5.023	ENSMUST00000018792.5	Dusp14	dual specificity phosphatase 14
chr1_+_153665274	4.911	ENSMUST00000152114.1 ENSMUST00000111812.1	Rgs8	regulator of G-protein signaling 8
chr2_-_57114970	4.775	ENSMUST00000028166.2	Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr4_+_125490688	4.164	ENSMUST00000030676.7	Grik3	glutamate receptor, ionotropic, kainate 3
chr1_+_153665666	3.990	ENSMUST00000111814.1 ENSMUST00000111810.1	Rgs8	regulator of G-protein signaling 8
chr18_-_46212595	3.860	ENSMUST00000037011.4	Trim36	tripartite motif-containing 36
chr9_-_43239816	3.843	ENSMUST00000034512.5	Oaf	OAF homolog (Drosophila)
chr1_+_153665587	3.440	ENSMUST00000147700.1	Rgs8	regulator of G-protein signaling 8
chr7_-_141443989	3.345	ENSMUST00000026580.5	Lrdd	leucine-rich and death domain containing
chr1_+_153665627	3.184	ENSMUST00000147482.1	Rgs8	regulator of G-protein signaling 8
chr6_-_94700137	3.112	ENSMUST00000101126.2 ENSMUST00000032105.4	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_35845204	3.090	ENSMUST00000164772.1 ENSMUST00000065173.2	Lingo2	leucine rich repeat and Ig domain containing 2
chr13_-_89742490	2.923	ENSMUST00000109546.2	Vcan	versican
chr6_+_7555053	2.840	ENSMUST00000090679.2 ENSMUST00000184986.1	Tac1	tachykinin 1
chr10_-_92162753	2.744	ENSMUST00000182197.1	Rmst	rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr12_+_3891728	2.622	ENSMUST00000172689.1 ENSMUST00000111186.1	Dnmt3a	DNA methyltransferase 3A
chr2_+_164562579	2.373	ENSMUST00000017867.3 ENSMUST00000109344.2 ENSMUST00000109345.2	Wfdc2	WAP four-disulfide core domain 2
chr4_-_132510493	2.273	ENSMUST00000030724.8	Sesn2	sestrin 2
chr4_-_134018829	2.245	ENSMUST00000051674.2	Lin28a	lin-28 homolog A (C. elegans)
chr7_-_115824699	2.101	ENSMUST00000169129.1	Sox6	SRY-box containing gene 6
chr14_-_51988829	2.064	ENSMUST00000181008.1	Gm16617	predicted gene, 16617
chr17_-_70849644	1.994	ENSMUST00000134654.1 ENSMUST00000172229.1 ENSMUST00000127719.1	Tgif1	TGFB-induced factor homeobox 1
chr5_+_115908644	1.859	ENSMUST00000141101.1	Cit	citron
chr14_+_62292475	1.735	ENSMUST00000166879.1	Rnaseh2b	ribonuclease H2, subunit B
chr1_+_170214826	1.686	ENSMUST00000159201.1 ENSMUST00000055830.1	4930500M09Rik	RIKEN cDNA 4930500M09 gene
chr19_+_20601958	1.644	ENSMUST00000087638.3	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1
chr16_-_50330987	1.567	ENSMUST00000114488.1	Bbx	bobby sox homolog (Drosophila)
chr4_-_123750236	1.543	ENSMUST00000102636.3	Akirin1	akirin 1
chr17_+_47630690	1.525	ENSMUST00000024779.8	Usp49	ubiquitin specific peptidase 49
chr10_-_120899067	1.472	ENSMUST00000092143.5	Msrb3	methionine sulfoxide reductase B3
chrX_+_142681398	1.385	ENSMUST00000112889.1 ENSMUST00000101198.2 ENSMUST00000112891.1 ENSMUST00000087333.2	Tmem164	transmembrane protein 164
chr3_+_75557530	1.381	ENSMUST00000161776.1 ENSMUST00000029423.8	Serpini1	serine (or cysteine) peptidase inhibitor, clade I, member 1
chrX_-_53269020	1.304	ENSMUST00000114838.1	Fam122b	family with sequence similarity 122, member B
chr2_+_20519776	1.293	ENSMUST00000114604.2 ENSMUST00000066509.3	Etl4	enhancer trap locus 4
chr18_+_60963517	1.224	ENSMUST00000115295.2 ENSMUST00000039904.6	Camk2a	calcium/calmodulin-dependent protein kinase II alpha
chr1_-_105356658	1.219	ENSMUST00000058688.5 ENSMUST00000172299.1	Rnf152	ring finger protein 152
chr6_+_61180313	1.206	ENSMUST00000126214.1	Ccser1	coiled-coil serine rich 1
chr2_+_54436317	1.161	ENSMUST00000112636.1 ENSMUST00000112635.1 ENSMUST00000112634.1	Galnt13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr6_-_127769427	1.145	ENSMUST00000032500.8	Prmt8	protein arginine N-methyltransferase 8
chr1_-_69108039	1.143	ENSMUST00000121473.1	Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr7_-_132813799	1.138	ENSMUST00000097998.2	Fam53b	family with sequence similarity 53, member B
chr9_-_69760924	1.132	ENSMUST00000071281.4	Foxb1	forkhead box B1
chr8_+_106870827	1.088	ENSMUST00000176144.1 ENSMUST00000175987.1	Has3	hyaluronan synthase 3
chr9_+_35421541	1.023	ENSMUST00000119129.2	Cdon	cell adhesion molecule-related/down-regulated by oncogenes
chr9_+_108296853	0.979	ENSMUST00000035230.5	Amt	aminomethyltransferase
chr4_-_109665249	0.968	ENSMUST00000063531.4	Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr7_-_132813528	0.952	ENSMUST00000097999.2	Fam53b	family with sequence similarity 53, member B
chr15_-_98831498	0.927	ENSMUST00000168846.1	Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr10_-_85916902	0.893	ENSMUST00000037646.7	Prdm4	PR domain containing 4
chr5_-_24329556	0.874	ENSMUST00000115098.2	Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chrX_-_152016269	0.845	ENSMUST00000026288.4	Ribc1	RIB43A domain with coiled-coils 1
chr7_-_132813715	0.844	ENSMUST00000134946.1	Fam53b	family with sequence similarity 53, member B
chr16_-_16527364	0.817	ENSMUST00000069284.7	Fgd4	FYVE, RhoGEF and PH domain containing 4
chr8_-_8639363	0.813	ENSMUST00000152698.1	Efnb2	ephrin B2
chr2_+_27079371	0.769	ENSMUST00000091233.6	Adamtsl2	ADAMTS-like 2
chr6_-_21851914	0.759	ENSMUST00000134635.1 ENSMUST00000123116.1 ENSMUST00000120965.1	Tspan12	tetraspanin 12
chrX_-_162829379	0.738	ENSMUST00000041370.4 ENSMUST00000112316.2 ENSMUST00000112315.1	Txlng	taxilin gamma
chr1_+_131970589	0.729	ENSMUST00000027695.6	Slc45a3	solute carrier family 45, member 3
chr4_-_42168603	0.711	ENSMUST00000098121.3	Gm13305	predicted gene 13305
chr4_+_43641262	0.709	ENSMUST00000123351.1 ENSMUST00000128549.1	Npr2	natriuretic peptide receptor 2
chr4_+_41760454	0.686	ENSMUST00000108040.1	Il11ra1	interleukin 11 receptor, alpha chain 1
chr3_+_102734496	0.672	ENSMUST00000029451.5	Tspan2	tetraspanin 2
chr14_+_56887795	0.669	ENSMUST00000022511.8	Zmym2	zinc finger, MYM-type 2
chr9_-_95845215	0.668	ENSMUST00000093800.2	Pls1	plastin 1 (I-isoform)
chr6_+_50110837	0.613	ENSMUST00000167628.1	Mpp6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr1_+_164115264	0.541	ENSMUST00000162746.1	Selp	selectin, platelet
chr12_+_55598917	0.528	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr3_+_51415986	0.519	ENSMUST00000029303.7	Naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr14_+_31251454	0.515	ENSMUST00000022458.4	Bap1	Brca1 associated protein 1
chr8_-_31918203	0.466	ENSMUST00000073884.4	Nrg1	neuregulin 1
chr2_-_60125651	0.461	ENSMUST00000112550.1	Baz2b	bromodomain adjacent to zinc finger domain, 2B
chr2_+_68861433	0.452	ENSMUST00000028426.2	Cers6	ceramide synthase 6
chr5_+_120513102	0.448	ENSMUST00000111889.1	Slc8b1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr15_+_99670574	0.435	ENSMUST00000023758.7	Asic1	acid-sensing (proton-gated) ion channel 1
chr4_+_11191354	0.430	ENSMUST00000170901.1	Ccne2	cyclin E2
chrX_+_20425688	0.403	ENSMUST00000115384.2	Phf16	PHD finger protein 16
chrX_+_153006461	0.402	ENSMUST00000095755.3	Usp51	ubiquitin specific protease 51
chr3_+_96629919	0.393	ENSMUST00000048915.6	Rbm8a	RNA binding motif protein 8a
chr9_-_13818665	0.386	ENSMUST00000150893.1 ENSMUST00000124883.1	Cep57	centrosomal protein 57
chr16_-_56024628	0.384	ENSMUST00000119981.1 ENSMUST00000096021.3	Pcnp	PEST proteolytic signal containing nuclear protein
chrM_+_9870	0.376	ENSMUST00000084013.1	mt-Nd4l	mitochondrially encoded NADH dehydrogenase 4L
chr9_+_27299205	0.374	ENSMUST00000115247.1 ENSMUST00000133213.1	Igsf9b	immunoglobulin superfamily, member 9B
chr11_+_98348404	0.373	ENSMUST00000078694.6	Ppp1r1b	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_-_161876656	0.365	ENSMUST00000048377.5	Suco	SUN domain containing ossification factor
chr2_+_68861564	0.350	ENSMUST00000176018.1	Cers6	ceramide synthase 6
chrX_+_42150672	0.341	ENSMUST00000069619.7	Stag2	stromal antigen 2
chr11_-_94507337	0.340	ENSMUST00000040692.8	Mycbpap	MYCBP associated protein
chr18_-_42899470	0.340	ENSMUST00000120632.1	Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_+_42151002	0.335	ENSMUST00000123245.1	Stag2	stromal antigen 2
chr18_-_42899294	0.329	ENSMUST00000117687.1	Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr10_-_128211788	0.327	ENSMUST00000061995.8	Spryd4	SPRY domain containing 4
chr1_-_24612700	0.309	ENSMUST00000088336.1	Gm10222	predicted gene 10222
chr9_+_37208291	0.285	ENSMUST00000034632.8	Tmem218	transmembrane protein 218
chr19_+_4097392	0.267	ENSMUST00000174514.1 ENSMUST00000174149.1	Cdk2ap2	CDK2-associated protein 2
chr5_-_24601961	0.246	ENSMUST00000030791.7	Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chrM_+_9452	0.238	ENSMUST00000082411.1	mt-Nd3	mitochondrially encoded NADH dehydrogenase 3
chrX_+_163909132	0.238	ENSMUST00000033734.7 ENSMUST00000112294.2	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit
chr17_+_35135695	0.236	ENSMUST00000174478.1 ENSMUST00000174281.2 ENSMUST00000173550.1	Bag6	BCL2-associated athanogene 6
chr7_-_30563184	0.234	ENSMUST00000043898.6	Psenen	presenilin enhancer 2 homolog (C. elegans)
chr15_+_80623499	0.231	ENSMUST00000043149.7	Grap2	GRB2-related adaptor protein 2
chr2_+_138278481	0.229	ENSMUST00000075410.4	Btbd3	BTB (POZ) domain containing 3
chr1_+_74236479	0.227	ENSMUST00000113820.2 ENSMUST00000006467.7 ENSMUST00000113819.1	Arpc2	actin related protein 2/3 complex, subunit 2
chr12_+_78861693	0.223	ENSMUST00000071230.7	Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha
chr19_+_6057925	0.216	ENSMUST00000179142.1	Fau	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr13_+_93304066	0.216	ENSMUST00000109493.1	Homer1	homer homolog 1 (Drosophila)
chr10_+_4710119	0.213	ENSMUST00000105588.1 ENSMUST00000105589.1	Esr1	estrogen receptor 1 (alpha)
chrM_+_7759	0.199	ENSMUST00000082407.1 ENSMUST00000082408.1	mt-Atp8 mt-Atp6	mitochondrially encoded ATP synthase 8 mitochondrially encoded ATP synthase 6
chr19_+_21272276	0.197	ENSMUST00000025659.4	Zfand5	zinc finger, AN1-type domain 5
chr10_+_80930071	0.192	ENSMUST00000015456.8	Gadd45b	growth arrest and DNA-damage-inducible 45 beta
chrM_+_10167	0.190	ENSMUST00000082414.1	mt-Nd4	mitochondrially encoded NADH dehydrogenase 4
chrX_+_56454871	0.189	ENSMUST00000039374.2 ENSMUST00000101553.2	Ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_+_127746775	0.186	ENSMUST00000033081.7	Fbxl19	F-box and leucine-rich repeat protein 19
chr3_-_154328634	0.176	ENSMUST00000167744.1	Lhx8	LIM homeobox protein 8
chr1_-_174921813	0.170	ENSMUST00000055294.3	Grem2	gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr7_-_46795661	0.166	ENSMUST00000123725.1	Hps5	Hermansky-Pudlak syndrome 5 homolog (human)
chr2_-_25272380	0.155	ENSMUST00000028342.6	Ssna1	Sjogren's syndrome nuclear autoantigen 1
chr3_-_103791537	0.151	ENSMUST00000118317.1	Hipk1	homeodomain interacting protein kinase 1
chr15_+_10952332	0.142	ENSMUST00000022853.8 ENSMUST00000110523.1	C1qtnf3	C1q and tumor necrosis factor related protein 3
chr11_-_69681903	0.138	ENSMUST00000066760.1	Senp3	SUMO/sentrin specific peptidase 3
chr11_-_22286795	0.137	ENSMUST00000109563.2 ENSMUST00000180360.1	Ehbp1	EH domain binding protein 1
chr19_+_55894508	0.137	ENSMUST00000142291.1	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr11_-_69681822	0.130	ENSMUST00000005336.2	Senp3	SUMO/sentrin specific peptidase 3
chr19_+_6057888	0.125	ENSMUST00000043074.5 ENSMUST00000178310.1	Fau	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr7_-_46795881	0.107	ENSMUST00000107653.1 ENSMUST00000107654.1 ENSMUST00000014562.7 ENSMUST00000152759.1	Hps5	Hermansky-Pudlak syndrome 5 homolog (human)
chr10_-_86705485	0.091	ENSMUST00000020238.7	Hsp90b1	heat shock protein 90, beta (Grp94), member 1
chr6_+_42286709	0.086	ENSMUST00000163936.1	Clcn1	chloride channel 1
chr4_-_117156144	0.080	ENSMUST00000102696.4	Rps8	ribosomal protein S8
chr19_-_19001099	0.072	ENSMUST00000040153.8 ENSMUST00000112828.1	Rorb	RAR-related orphan receptor beta
chr18_+_34840575	0.071	ENSMUST00000043484.7	Reep2	receptor accessory protein 2
chrM_+_8600	0.070	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr8_+_79028317	0.063	ENSMUST00000087927.4 ENSMUST00000098614.2	Zfp827	zinc finger protein 827
chr1_+_180726019	0.061	ENSMUST00000027780.4	Acbd3	acyl-Coenzyme A binding domain containing 3
chr19_-_6057736	0.048	ENSMUST00000007482.6	Mrpl49	mitochondrial ribosomal protein L49
chr9_+_35211155	0.044	ENSMUST00000034541.5	Srpr	signal recognition particle receptor ('docking protein')
chr7_+_130577334	0.036	ENSMUST00000059145.7 ENSMUST00000084513.4	Tacc2	transforming, acidic coiled-coil containing protein 2
chr18_+_65582390	0.032	ENSMUST00000169679.1 ENSMUST00000183326.1	Zfp532	zinc finger protein 532
chr8_-_4259257	0.019	ENSMUST00000053252.7	Ctxn1	cortexin 1
chrX_+_140956892	0.016	ENSMUST00000112971.1	Atg4a	autophagy related 4A, cysteine peptidase
chr17_-_56982120	0.013	ENSMUST00000056113.4	Acer1	alkaline ceramidase 1
chr5_-_137786651	0.012	ENSMUST00000031740.9	Mepce	methylphosphate capping enzyme
chr17_+_48932368	0.010	ENSMUST00000046254.2	Lrfn2	leucine rich repeat and fibronectin type III domain containing 2
chr3_-_19311269	0.010	ENSMUST00000099195.3	Pde7a	phosphodiesterase 7A
chr9_+_120929216	0.007	ENSMUST00000130466.1	Ctnnb1	catenin (cadherin associated protein), beta 1
chr3_-_103791075	0.002	ENSMUST00000106845.2 ENSMUST00000029438.8 ENSMUST00000121324.1	Hipk1	homeodomain interacting protein kinase 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	11.6	GO:0035262	gonad morphogenesis(GO:0035262)
1.9	22.8	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.6	7.8	GO:0007386	compartment pattern specification(GO:0007386)
1.4	2.8	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.2	4.8	GO:0051866	general adaptation syndrome(GO:0051866)
1.1	15.5	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.0	3.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.8	2.3	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.7	8.4	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.6	5.4	GO:0071493	cellular response to UV-B(GO:0071493)
0.5	1.1	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4	1.6	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4	4.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4	1.5	GO:0030091	protein repair(GO:0030091)
0.3	2.6	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.3	1.0	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3	1.5	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3	1.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3	1.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.3	1.1	GO:0007412	axon target recognition(GO:0007412)
0.3	9.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2	2.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.2	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.2	0.7	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2	0.7	GO:0001951	intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.2	2.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2	1.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.2	0.7	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	3.9	GO:0007340	acrosome reaction(GO:0007340)
0.1	5.7	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.9	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	0.4	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.8	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1	2.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.5	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	1.0	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	0.4	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	1.2	GO:0099628	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1	1.9	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.8	GO:0030035	microspike assembly(GO:0030035)
0.1	1.7	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.1	0.7	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.5	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.1	0.2	GO:2000812	response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.1	0.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.5	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.2	GO:0060737	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1	3.1	GO:0035411	catenin import into nucleus(GO:0035411)
0.1	12.5	GO:0050807	regulation of synapse organization(GO:0050807)
0.1	0.5	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.8	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.1	2.4	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.7	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.4	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.2	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.2	GO:0071384	cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0	0.2	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.1	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0	0.2	GO:0036506	maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.9	GO:0010842	retina layer formation(GO:0010842)
0.0	0.3	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.2	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.3	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	1.2	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.3	GO:0016926	protein desumoylation(GO:0016926)
0.0	3.3	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.0	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.1	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.4	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0046549	retinal cone cell development(GO:0046549)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.6	GO:0030500	regulation of bone mineralization(GO:0030500)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0070557	PCNA-p21 complex(GO:0070557)
0.4	1.2	GO:0099573	glutamatergic postsynaptic density(GO:0099573)
0.4	15.5	GO:0032809	neuronal cell body membrane(GO:0032809)
0.3	1.4	GO:0031983	vesicle lumen(GO:0031983)
0.3	1.7	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.3	2.3	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	0.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.4	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	10.4	GO:0005581	collagen trimer(GO:0005581)
0.1	0.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	4.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.7	GO:1990357	terminal web(GO:1990357)
0.1	21.9	GO:0032993	protein-DNA complex(GO:0032993)
0.1	2.6	GO:0001741	XY body(GO:0001741)
0.1	0.3	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.5	GO:0031415	NatA complex(GO:0031415)
0.1	0.9	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0097450	astrocyte end-foot(GO:0097450)
0.0	3.9	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	1.9	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.2	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	2.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	0.2	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.5	GO:0030673	axolemma(GO:0030673)
0.0	1.2	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	5.3	GO:0016607	nuclear speck(GO:0016607)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.5	GO:0031519	PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.8	4.2	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.6	9.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5	2.4	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.4	2.3	GO:0070728	leucine binding(GO:0070728)
0.4	1.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.4	15.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.3	1.6	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3	2.6	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	1.7	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2	1.5	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2	0.7	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2	1.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2	1.1	GO:0038132	neuregulin binding(GO:0038132)
0.2	7.8	GO:0005112	Notch binding(GO:0005112)
0.2	2.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.2	0.8	GO:0050436	microfibril binding(GO:0050436)
0.2	0.9	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2	0.7	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2	2.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	2.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.5	GO:0042806	fucose binding(GO:0042806)
0.1	0.4	GO:0031752	D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1	0.4	GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1	1.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	0.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.8	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	1.0	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	18.4	GO:0001047	core promoter binding(GO:0001047)
0.1	1.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	1.7	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.9	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	1.0	GO:0008483	transaminase activity(GO:0008483)
0.0	0.7	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.5	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.8	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	5.4	GO:0000287	magnesium ion binding(GO:0000287)
0.0	3.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.3	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.2	GO:0036122	BMP binding(GO:0036122)
0.0	0.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.4	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.4	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.7	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.6	PID_ERBB_NETWORK_PATHWAY	ErbB receptor signaling network
0.1	2.9	PID_TOLL_ENDOGENOUS_PATHWAY	Endogenous TLR signaling
0.1	10.4	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	8.0	PID_NOTCH_PATHWAY	Notch signaling pathway
0.1	3.1	PID_ERBB4_PATHWAY	ErbB4 signaling events
0.1	1.2	ST_WNT_CA2_CYCLIC_GMP_PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	1.0	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	2.3	PID_MYC_REPRESS_PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	SA_REG_CASCADE_OF_CYCLIN_EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.9	PID_RHOA_PATHWAY	RhoA signaling pathway
0.0	0.2	PID_FOXO_PATHWAY	FoxO family signaling
0.0	0.8	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID_TCR_JNK_PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.5	PID_AMB2_NEUTROPHILS_PATHWAY	amb2 Integrin signaling
0.0	1.4	PID_LKB1_PATHWAY	LKB1 signaling events
0.0	2.0	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	PID_ATR_PATHWAY	ATR signaling pathway
0.0	0.9	PID_P75_NTR_PATHWAY	p75(NTR)-mediated signaling
0.0	1.0	PID_E2F_PATHWAY	E2F transcription factor network
0.0	2.1	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.7	PID_PLK1_PATHWAY	PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	REACTOME_ETHANOL_OXIDATION	Genes involved in Ethanol oxidation
0.2	4.2	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	2.9	REACTOME_CS_DS_DEGRADATION	Genes involved in CS/DS degradation
0.2	3.1	REACTOME_SIGNALING_BY_EGFR_IN_CANCER	Genes involved in Signaling by EGFR in Cancer
0.2	5.4	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	14.8	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	Genes involved in G alpha (i) signalling events
0.1	1.1	REACTOME_HYALURONAN_METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.9	REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	2.8	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	1.6	REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	1.7	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.2	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.0	REACTOME_MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME_G0_AND_EARLY_G1	Genes involved in G0 and Early G1
0.0	1.0	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.9	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.2	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.7	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	3.3	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.2	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR	Genes involved in Trafficking and processing of endosomal TLR

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