Motif ID: Tbx3

Z-value: 0.238


Transcription factors associated with Tbx3:

Gene SymbolEntrez IDGene Name
Tbx3 ENSMUSG00000018604.12 Tbx3



Activity profile for motif Tbx3.

activity profile for motif Tbx3


Sorted Z-values histogram for motif Tbx3

Sorted Z-values for motif Tbx3



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_100970887 0.952 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr19_+_7056731 0.721 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr7_+_112374839 0.557 ENSMUST00000106645.1
 Micalcl
MICAL C-terminal like
chr10_-_18743691 0.489 ENSMUST00000019999.5
 D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr7_-_4522427 0.424 ENSMUST00000098859.3
 Tnni3
troponin I, cardiac 3
chr7_+_107567445 0.273 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr1_-_31222604 0.248 ENSMUST00000127775.1
 4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr19_+_7494033 0.234 ENSMUST00000170373.1
 Atl3
atlastin GTPase 3
chr12_+_84362029 0.224 ENSMUST00000110278.1
ENSMUST00000145522.1
 Coq6

coenzyme Q6 homolog (yeast)

chr5_-_106926245 0.220 ENSMUST00000117588.1
 Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr18_-_23981555 0.201 ENSMUST00000115829.1
 Zscan30
zinc finger and SCAN domain containing 30
chr12_+_84361636 0.200 ENSMUST00000110276.1
 Coq6
coenzyme Q6 homolog (yeast)
chr12_+_84361968 0.187 ENSMUST00000021661.6
 Coq6
coenzyme Q6 homolog (yeast)
chr7_-_4522794 0.154 ENSMUST00000140424.1
 Tnni3
troponin I, cardiac 3
chr11_-_94507337 0.126 ENSMUST00000040692.8
 Mycbpap
MYCBP associated protein
chr1_+_93215899 0.100 ENSMUST00000138595.1
 E030010N08Rik
RIKEN cDNA E030010N08 gene
chr12_-_84361802 0.066 ENSMUST00000021659.1
ENSMUST00000065536.2
 Fam161b

family with sequence similarity 161, member B

chr7_-_118443549 0.056 ENSMUST00000081574.4
 Syt17
synaptotagmin XVII
chr18_-_43393346 0.043 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr7_-_28949670 0.032 ENSMUST00000148196.1
 Actn4
actinin alpha 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030172 troponin C binding(GO:0030172)
0.0 0.6 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.0 0.7 GO:0019213 deacetylase activity(GO:0019213)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction