Motif ID: Tcf21_Msc

Z-value: 1.157

Transcription factors associated with Tcf21_Msc:

Gene SymbolEntrez IDGene Name
Msc ENSMUSG00000025930.5 Msc
Tcf21 ENSMUSG00000045680.7 Tcf21






Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf21_Msc

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144893077 8.717 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr3_+_90537242 5.836 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr1_-_14310198 5.485 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr4_+_144892813 5.467 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_-_28210022 5.389 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr3_+_90537306 5.012 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr7_+_122289297 4.788 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr11_+_113619318 4.234 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr4_+_144893127 4.094 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr3_-_84305385 3.831 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr4_+_48045144 3.757 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr6_+_29398920 3.741 ENSMUST00000181464.1
ENSMUST00000180829.1
Ccdc136

coiled-coil domain containing 136

chr6_-_54566484 3.723 ENSMUST00000019268.4
Scrn1
secernin 1
chr9_-_40346290 3.661 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr16_+_43510267 3.602 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr11_+_99864476 3.200 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr4_+_11156411 3.188 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr7_+_25152456 3.180 ENSMUST00000098678.1
D930028M14Rik
RIKEN cDNA D930028M14 gene
chr5_-_140389188 3.157 ENSMUST00000031539.7
Snx8
sorting nexin 8
chr6_+_80018877 3.144 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr1_-_97977233 3.109 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr4_-_87806276 3.070 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_107915041 2.956 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr4_-_87806296 2.920 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr6_+_80019008 2.901 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr8_-_122432924 2.857 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr10_+_79854618 2.835 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr2_-_170131156 2.721 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr14_+_55478753 2.704 ENSMUST00000022821.6
Dhrs4
dehydrogenase/reductase (SDR family) member 4
chr5_-_28210168 2.681 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr10_+_79854658 2.672 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr7_+_28180226 2.445 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr1_-_155232710 2.444 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr7_+_51621830 2.428 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr10_-_27616895 2.414 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr5_+_21186267 2.382 ENSMUST00000036031.8
Gsap
gamma-secretase activating protein
chr10_-_18743691 2.364 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr2_+_26973416 2.298 ENSMUST00000014996.7
ENSMUST00000102891.3
Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chr7_+_45216671 2.249 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr14_-_56571830 2.228 ENSMUST00000065302.7
Cenpj
centromere protein J
chr7_-_80688852 2.218 ENSMUST00000122255.1
Crtc3
CREB regulated transcription coactivator 3
chr15_+_25622525 2.205 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr3_+_14863495 2.199 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr6_+_112273758 2.172 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr7_+_28180272 2.139 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chrX_-_142306170 2.111 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr11_-_109611417 2.082 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chr7_-_52005792 2.039 ENSMUST00000098414.3
Svip
small VCP/p97-interacting protein
chr15_+_78926720 2.029 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr3_+_95588960 1.993 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr3_+_95588928 1.986 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr16_-_16560201 1.969 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr2_-_105399286 1.896 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr5_+_64160207 1.834 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr5_+_103754560 1.821 ENSMUST00000153165.1
ENSMUST00000031256.5
Aff1

AF4/FMR2 family, member 1

chr7_-_116038734 1.801 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr5_+_91517615 1.760 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr3_+_95588990 1.759 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr10_+_118860826 1.705 ENSMUST00000059966.4
4932442E05Rik
RIKEN cDNA 4932442E05 gene
chr9_-_78587968 1.675 ENSMUST00000117645.1
ENSMUST00000119213.1
ENSMUST00000052441.5
Slc17a5


solute carrier family 17 (anion/sugar transporter), member 5


chr12_+_52516077 1.641 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr16_-_16560046 1.633 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr8_+_46163733 1.611 ENSMUST00000110376.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr6_-_115251839 1.582 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr15_-_58135047 1.564 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr7_+_29071597 1.550 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr3_+_89436699 1.531 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr13_-_100786402 1.516 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chrX_+_36328353 1.513 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr17_-_51826562 1.507 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr6_-_93913678 1.491 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr11_+_101665541 1.483 ENSMUST00000039388.2
Arl4d
ADP-ribosylation factor-like 4D
chr15_+_89429560 1.478 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr8_+_94172618 1.473 ENSMUST00000034214.6
Mt2
metallothionein 2
chr2_-_140170528 1.467 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr14_-_88471396 1.466 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr2_+_84734050 1.458 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr6_+_29694204 1.447 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chrX_+_141475385 1.442 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr9_+_58134535 1.442 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr6_+_55836878 1.412 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr14_+_30879257 1.402 ENSMUST00000040715.6
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr3_+_96557950 1.353 ENSMUST00000074519.6
ENSMUST00000049093.7
Txnip

thioredoxin interacting protein

chr6_-_28261907 1.344 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr18_+_60293372 1.341 ENSMUST00000171297.1
F830016B08Rik
RIKEN cDNA F830016B08 gene
chr13_-_113046357 1.314 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chrX_+_56454871 1.313 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr3_+_86084434 1.300 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chrX_+_71663665 1.291 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr15_-_102722120 1.287 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr15_-_102722150 1.262 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr12_-_91779129 1.245 ENSMUST00000170077.1
Ston2
stonin 2
chr5_-_36830647 1.218 ENSMUST00000031002.3
Man2b2
mannosidase 2, alpha B2
chr17_-_51833278 1.208 ENSMUST00000133574.1
Satb1
special AT-rich sequence binding protein 1
chrX_-_164027965 1.206 ENSMUST00000033739.4
Car5b
carbonic anhydrase 5b, mitochondrial
chr5_+_135725713 1.203 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr19_+_3323301 1.198 ENSMUST00000025835.4
Cpt1a
carnitine palmitoyltransferase 1a, liver
chr6_+_125049952 1.179 ENSMUST00000088294.5
ENSMUST00000032481.7
Acrbp

proacrosin binding protein

chr14_-_62456286 1.136 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr4_-_42168603 1.133 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr9_-_22307638 1.125 ENSMUST00000086278.6
Zfp810
zinc finger protein 810
chr6_-_134632388 1.119 ENSMUST00000047443.3
Mansc1
MANSC domain containing 1
chr12_-_119238794 1.101 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr8_+_46739745 1.083 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr15_-_89429851 1.076 ENSMUST00000023289.6
Chkb
choline kinase beta
chr8_+_94977101 1.075 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr7_-_24208093 1.067 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr7_+_28179469 1.063 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr7_+_141455198 1.047 ENSMUST00000164016.1
ENSMUST00000064151.6
ENSMUST00000169665.1
Pnpla2


patatin-like phospholipase domain containing 2


chr1_-_36535719 1.038 ENSMUST00000054665.4
Ankrd23
ankyrin repeat domain 23
chr2_-_18392736 1.005 ENSMUST00000091418.5
ENSMUST00000166495.1
Dnajc1

DnaJ (Hsp40) homolog, subfamily C, member 1

chr1_-_87156127 1.004 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr3_+_35754121 0.993 ENSMUST00000108186.1
ENSMUST00000029257.8
Atp11b

ATPase, class VI, type 11B

chr14_-_31830402 0.990 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr10_-_78487842 0.989 ENSMUST00000069431.4
Gm9978
predicted gene 9978
chr2_+_25262589 0.977 ENSMUST00000114336.3
Tprn
taperin
chr1_-_121327672 0.971 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr3_+_107877227 0.967 ENSMUST00000037375.8
Eps8l3
EPS8-like 3
chr7_-_80405425 0.965 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr5_-_116591811 0.964 ENSMUST00000076124.5
Srrm4
serine/arginine repetitive matrix 4
chr9_+_85842852 0.960 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr15_-_75894474 0.956 ENSMUST00000023237.6
Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr11_+_99041237 0.939 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chr11_-_95076797 0.938 ENSMUST00000145671.1
ENSMUST00000120375.1
Itga3

integrin alpha 3

chrX_+_101449078 0.937 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr6_+_34746368 0.935 ENSMUST00000142716.1
Cald1
caldesmon 1
chr2_-_180954676 0.919 ENSMUST00000148905.1
ENSMUST00000103053.3
ENSMUST00000108873.2
Nkain4


Na+/K+ transporting ATPase interacting 4


chr5_-_72559599 0.917 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr16_-_43664145 0.911 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr2_-_161109017 0.908 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr7_-_127993831 0.904 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chr17_-_35700520 0.897 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr7_+_142472080 0.894 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr5_+_123749696 0.892 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr2_-_180954620 0.889 ENSMUST00000139929.1
Nkain4
Na+/K+ transporting ATPase interacting 4
chr11_-_40733373 0.888 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr8_+_45885479 0.876 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr8_+_46163651 0.871 ENSMUST00000034048.6
ENSMUST00000145229.1
4933411K20Rik

RIKEN cDNA 4933411K20 gene

chr1_-_54557595 0.867 ENSMUST00000097739.3
Pgap1
post-GPI attachment to proteins 1
chr16_-_50432340 0.863 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr4_-_133967893 0.862 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr1_-_121327734 0.857 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr4_-_20778527 0.846 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chrX_+_73483602 0.831 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr9_+_104063376 0.828 ENSMUST00000120854.1
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr3_+_89436736 0.828 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr1_-_133424377 0.826 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr7_+_142471838 0.821 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr11_+_102189620 0.813 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr5_-_131538687 0.811 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr2_-_118549668 0.803 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chrM_+_7005 0.803 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr11_+_112782182 0.792 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr2_-_52335134 0.784 ENSMUST00000075301.3
Neb
nebulin
chrX_-_23266751 0.779 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr1_+_61638819 0.774 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr1_+_36511867 0.767 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr10_+_127759721 0.761 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr5_-_73647713 0.761 ENSMUST00000081170.7
Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr1_+_74791516 0.756 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr11_+_70657687 0.754 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr4_-_155863362 0.752 ENSMUST00000030949.3
Tas1r3
taste receptor, type 1, member 3
chr2_-_5862923 0.738 ENSMUST00000071016.2
Gm13199
predicted gene 13199
chr7_-_120202104 0.722 ENSMUST00000033198.5
Crym
crystallin, mu
chr4_-_133967235 0.721 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_117523526 0.718 ENSMUST00000132261.1
Gm11734
predicted gene 11734
chr11_-_95076657 0.714 ENSMUST00000001548.7
Itga3
integrin alpha 3
chr4_-_133967296 0.709 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chrX_+_48108912 0.708 ENSMUST00000114998.1
ENSMUST00000115000.3
Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

chr8_+_127064107 0.704 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr1_+_167598450 0.699 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr7_+_126781483 0.699 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr15_-_100599983 0.693 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr1_+_167598384 0.691 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr5_-_125058367 0.684 ENSMUST00000134404.1
Ncor2
nuclear receptor co-repressor 2
chr2_-_27246814 0.681 ENSMUST00000149733.1
Sardh
sarcosine dehydrogenase
chr9_+_53537021 0.676 ENSMUST00000035850.7
Npat
nuclear protein in the AT region
chr9_+_104063678 0.676 ENSMUST00000047799.5
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr4_+_133176336 0.671 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr1_-_189343704 0.670 ENSMUST00000180044.1
ENSMUST00000110920.1
Kcnk2

potassium channel, subfamily K, member 2

chr13_-_119408985 0.663 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr10_-_56228636 0.663 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr15_-_97767798 0.662 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr9_-_52168111 0.661 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chrX_+_109095359 0.661 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr1_+_36307745 0.660 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr14_-_72709534 0.659 ENSMUST00000162478.1
Fndc3a
fibronectin type III domain containing 3A
chr1_-_133921393 0.652 ENSMUST00000048432.5
Prelp
proline arginine-rich end leucine-rich repeat
chr12_+_32954179 0.647 ENSMUST00000020885.6
Sypl
synaptophysin-like protein
chr7_-_131410325 0.646 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr4_-_133967953 0.634 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr2_+_125068118 0.632 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr13_+_83721357 0.631 ENSMUST00000131907.2
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr19_+_4510472 0.631 ENSMUST00000068004.6
Pcx
pyruvate carboxylase
chr10_-_95415283 0.630 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr9_+_57130690 0.629 ENSMUST00000160147.1
ENSMUST00000161663.1
ENSMUST00000034836.9
ENSMUST00000161182.1
Man2c1



mannosidase, alpha, class 2C, member 1



chr8_+_45627709 0.627 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr1_-_192855723 0.612 ENSMUST00000155579.1
Sertad4
SERTA domain containing 4
chr4_-_148444744 0.608 ENSMUST00000051633.2
Ubiad1
UbiA prenyltransferase domain containing 1
chr15_-_97767644 0.605 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 18.3 GO:0042572 retinol metabolic process(GO:0042572)
1.3 3.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.1 3.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
1.0 5.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.0 4.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.7 2.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.6 2.9 GO:0003105 negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.5 1.5 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.5 2.4 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.5 4.2 GO:0030035 microspike assembly(GO:0030035)
0.4 2.2 GO:0061511 centriole elongation(GO:0061511)
0.4 6.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.4 4.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 2.7 GO:0042574 retinal metabolic process(GO:0042574)
0.4 4.2 GO:0030432 peristalsis(GO:0030432)
0.4 5.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.4 1.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 2.0 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.3 0.7 GO:1905076 regulation of interleukin-17 secretion(GO:1905076)
0.3 6.0 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.3 1.3 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.3 3.3 GO:0009404 toxin metabolic process(GO:0009404)
0.3 0.9 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.3 2.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.3 0.9 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 1.2 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.3 1.4 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.3 3.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.3 1.4 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.3 3.6 GO:0001675 acrosome assembly(GO:0001675)
0.3 2.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.3 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 0.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 2.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 0.8 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.3 1.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.2 1.0 GO:0090472 dibasic protein processing(GO:0090472)
0.2 2.1 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.7 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 0.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 0.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 2.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 1.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 2.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 0.4 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.2 0.6 GO:1990523 bone regeneration(GO:1990523)
0.2 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 3.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 0.5 GO:0036292 DNA rewinding(GO:0036292)
0.2 4.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 0.5 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.3 GO:0035106 operant conditioning(GO:0035106)
0.2 0.8 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.2 1.4 GO:0002347 response to tumor cell(GO:0002347)
0.2 0.9 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.1 1.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 5.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 2.3 GO:0060363 negative regulation of fatty acid biosynthetic process(GO:0045717) cranial suture morphogenesis(GO:0060363)
0.1 0.3 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 2.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 3.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 1.0 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 0.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.9 GO:0015791 polyol transport(GO:0015791)
0.1 0.5 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 3.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.8 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 2.2 GO:0048368 notochord development(GO:0030903) lateral mesoderm development(GO:0048368)
0.1 0.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 1.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 1.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1 0.5 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.1 0.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.9 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 0.9 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 9.8 GO:0051592 response to calcium ion(GO:0051592)
0.1 0.8 GO:0007625 grooming behavior(GO:0007625)
0.1 0.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1 0.3 GO:0046618 drug export(GO:0046618)
0.1 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.3 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.5 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 1.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.3 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.1 2.3 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 1.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.8 GO:0001523 retinoid metabolic process(GO:0001523)
0.1 1.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.8 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.7 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.3 GO:0071476 cellular hypotonic response(GO:0071476)
0.1 1.0 GO:0043010 camera-type eye development(GO:0043010)
0.1 0.2 GO:0042117 monocyte activation(GO:0042117)
0.1 0.5 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.5 GO:0090003 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 1.4 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0061009 common bile duct development(GO:0061009)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 2.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.0 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.9 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 2.4 GO:0007569 cell aging(GO:0007569)
0.0 1.7 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.9 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0061365 intestinal cholesterol absorption(GO:0030299) positive regulation of triglyceride lipase activity(GO:0061365) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.2 GO:0072429 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0006721 terpenoid metabolic process(GO:0006721)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:1901525 positive regulation of autophagosome maturation(GO:1901098) negative regulation of macromitophagy(GO:1901525)
0.0 0.4 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 1.2 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0034115 negative regulation of heterotypic cell-cell adhesion(GO:0034115) cell-cell adhesion involved in gastrulation(GO:0070586) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.2 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.4 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 1.1 GO:0030879 mammary gland development(GO:0030879)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.9 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.6 2.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 1.7 GO:0071438 integrin alpha3-beta1 complex(GO:0034667) invadopodium membrane(GO:0071438)
0.4 1.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 1.3 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.3 0.9 GO:1990423 RZZ complex(GO:1990423)
0.3 2.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.9 GO:0061702 inflammasome complex(GO:0061702)
0.2 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 7.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 3.7 GO:0002080 acrosomal membrane(GO:0002080)
0.2 7.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.3 GO:0016011 dystroglycan complex(GO:0016011)
0.1 2.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 2.4 GO:0005605 basal lamina(GO:0005605)
0.1 0.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 2.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.5 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 6.4 GO:0031985 Golgi cisterna(GO:0031985)
0.1 5.8 GO:0031526 brush border membrane(GO:0031526)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 3.1 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 6.0 GO:0030175 filopodium(GO:0030175)
0.1 0.5 GO:0061574 ASAP complex(GO:0061574)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 2.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 5.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.2 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0005770 late endosome(GO:0005770)
0.0 8.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 12.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0044297 cell body(GO:0044297)
0.0 1.0 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.0 3.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.9 5.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.9 2.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.8 4.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.8 2.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.7 2.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.5 1.5 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.4 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 1.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 0.9 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 1.2 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.3 2.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 3.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.1 GO:0004103 choline kinase activity(GO:0004103)
0.3 2.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.2 3.7 GO:0016805 dipeptidase activity(GO:0016805)
0.2 6.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.7 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 2.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.6 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 6.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 4.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.3 GO:0004568 chitinase activity(GO:0004568)
0.1 2.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.0 GO:0031432 titin binding(GO:0031432)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.7 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.3 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 1.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.8 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.8 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 1.3 GO:0043236 laminin binding(GO:0043236)
0.1 0.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.6 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 4.7 GO:0016209 antioxidant activity(GO:0016209)
0.1 0.5 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.2 GO:0034481 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin sulfotransferase activity(GO:0034481)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 9.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 3.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 5.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.7 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 2.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 5.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 2.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 18.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 1.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 1.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 1.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 0.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.3 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 1.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 3.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 2.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.8 PID_FOXO_PATHWAY FoxO family signaling
0.0 4.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.2 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 3.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID_P73PATHWAY p73 transcription factor network
0.0 2.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 1.9 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.9 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.8 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.7 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 7.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.2 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 1.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 4.0 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 3.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 5.4 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.2 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.2 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.0 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol