Motif ID: Tcf7l1

Z-value: 0.881


Transcription factors associated with Tcf7l1:

Gene SymbolEntrez IDGene Name
Tcf7l1 ENSMUSG00000055799.7 Tcf7l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72788952_727890610.325.3e-02Click!


Activity profile for motif Tcf7l1.

activity profile for motif Tcf7l1


Sorted Z-values histogram for motif Tcf7l1

Sorted Z-values for motif Tcf7l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf7l1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_108921648 3.450 ENSMUST00000144511.1
Axin2
axin2
chr11_+_108920800 3.124 ENSMUST00000140821.1
Axin2
axin2
chr2_+_153031852 3.010 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr2_+_152081529 2.472 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr7_-_115824699 2.345 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr7_+_45216671 2.187 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr3_+_131110350 2.022 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr1_-_183147461 1.743 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr18_-_62756275 1.678 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr9_+_119402444 1.592 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr18_+_82914632 1.486 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr10_+_80150448 1.481 ENSMUST00000153477.1
Midn
midnolin
chr7_+_100493795 1.464 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_-_35697971 1.433 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr2_+_124610573 1.361 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr13_-_54687644 1.359 ENSMUST00000129881.1
Rnf44
ring finger protein 44
chr9_+_35423582 1.312 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr17_+_3326552 1.307 ENSMUST00000169838.1
Tiam2
T cell lymphoma invasion and metastasis 2
chr8_+_79028587 1.235 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr14_+_27039001 1.225 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr17_-_47924460 1.214 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr17_-_47924400 1.214 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr2_+_173021902 1.188 ENSMUST00000029014.9
Rbm38
RNA binding motif protein 38
chr14_-_52020698 1.162 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr4_-_126468580 1.160 ENSMUST00000097888.3
Ago1
argonaute RISC catalytic subunit 1
chr6_-_148944750 1.159 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr10_+_80151154 1.152 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr14_-_98169542 1.150 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chrX_-_143933089 1.125 ENSMUST00000087313.3
Dcx
doublecortin
chr8_-_122678072 1.123 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr5_-_131538687 1.120 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr2_-_65529275 1.108 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr8_+_45507768 1.092 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr5_-_123012874 1.073 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr1_+_158362330 1.071 ENSMUST00000170718.1
Astn1
astrotactin 1
chr5_+_44100442 1.070 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr12_-_54986363 1.069 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr4_+_62583568 1.060 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr17_+_75005523 1.040 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr2_+_173022360 1.039 ENSMUST00000173997.1
Rbm38
RNA binding motif protein 38
chr3_+_32708546 0.990 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr16_+_4968936 0.982 ENSMUST00000090457.5
4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr16_-_34513944 0.947 ENSMUST00000151491.1
ENSMUST00000114960.2
Kalrn

kalirin, RhoGEF kinase

chr1_+_136467958 0.934 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr10_+_80300997 0.930 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr17_-_70851189 0.908 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr15_-_98871175 0.881 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr2_+_35582829 0.877 ENSMUST00000135741.1
Dab2ip
disabled 2 interacting protein
chr19_-_5729618 0.873 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr16_-_34514084 0.848 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr11_+_108920342 0.840 ENSMUST00000052915.7
Axin2
axin2
chr8_-_69184177 0.837 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr15_+_34238026 0.836 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr6_+_51432678 0.827 ENSMUST00000160133.1
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr9_+_85842852 0.823 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr17_+_28691419 0.821 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr5_-_114380459 0.819 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chr2_+_70474923 0.814 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr9_+_21616166 0.805 ENSMUST00000034707.8
ENSMUST00000098948.3
Smarca4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr2_+_164823001 0.767 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr4_+_85205120 0.765 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr9_+_110132015 0.763 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr1_-_182019927 0.753 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr6_+_17065129 0.740 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr7_-_144939823 0.739 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr8_+_79028317 0.733 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr7_-_83884289 0.730 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chr13_-_29984219 0.714 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr7_-_105787544 0.714 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr8_+_31111816 0.706 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr6_-_122340499 0.695 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr3_-_25212720 0.691 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr7_+_67655414 0.691 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr5_+_65131184 0.689 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr12_+_31265279 0.689 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr19_-_41802028 0.681 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr9_+_102717668 0.681 ENSMUST00000035121.7
Amotl2
angiomotin-like 2
chr5_+_110135823 0.680 ENSMUST00000112519.2
ENSMUST00000014812.8
Chfr

checkpoint with forkhead and ring finger domains

chr4_-_142239356 0.676 ENSMUST00000036476.3
Kazn
kazrin, periplakin interacting protein
chr13_-_97747399 0.672 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_69586021 0.664 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr2_+_157560078 0.645 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr8_-_34146974 0.645 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr6_+_29735667 0.635 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr1_-_64122256 0.631 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr4_+_132638987 0.612 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
Eya3




eyes absent 3 homolog (Drosophila)




chr17_-_89910449 0.611 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr16_-_17132377 0.608 ENSMUST00000023453.7
Sdf2l1
stromal cell-derived factor 2-like 1
chr9_-_65580040 0.598 ENSMUST00000068944.7
Plekho2
pleckstrin homology domain containing, family O member 2
chr13_-_97747373 0.592 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_91376433 0.586 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr11_+_117332335 0.580 ENSMUST00000106349.1
Sept9
septin 9
chr9_-_66124872 0.572 ENSMUST00000034946.8
Snx1
sorting nexin 1
chr9_-_65021645 0.559 ENSMUST00000036615.5
Ptplad1
protein tyrosine phosphatase-like A domain containing 1
chr19_-_47919269 0.556 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr7_+_127233227 0.554 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr11_+_3649759 0.553 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr13_-_41273977 0.543 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr9_+_107569112 0.541 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr5_-_114380505 0.525 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr11_-_78497734 0.508 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr5_-_102069905 0.506 ENSMUST00000053177.7
ENSMUST00000174698.1
Wdfy3

WD repeat and FYVE domain containing 3

chr6_-_47813512 0.499 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr19_-_30549516 0.492 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr5_+_34549568 0.478 ENSMUST00000118545.1
Sh3bp2
SH3-domain binding protein 2
chr17_+_46202740 0.475 ENSMUST00000087031.5
Xpo5
exportin 5
chr11_+_121237216 0.473 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr3_-_75956888 0.458 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr12_+_31265234 0.456 ENSMUST00000169088.1
Lamb1
laminin B1
chr11_+_3330781 0.453 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr7_-_105787567 0.450 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr3_+_53463666 0.447 ENSMUST00000058577.4
Proser1
proline and serine rich 1
chr11_-_6274830 0.445 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chr9_+_119444923 0.430 ENSMUST00000035094.6
ENSMUST00000164213.2
Exog

endo/exonuclease (5'-3'), endonuclease G-like

chr12_-_98737405 0.429 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr6_+_83137089 0.427 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr7_-_126897424 0.419 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr17_+_34604262 0.404 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr4_+_107802277 0.402 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
Lrp8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr1_-_78968079 0.393 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr1_+_132008285 0.381 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr6_+_51432663 0.375 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr1_+_161142706 0.375 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr2_-_165034821 0.370 ENSMUST00000153905.1
ENSMUST00000040381.8
Ncoa5

nuclear receptor coactivator 5

chr19_-_37330613 0.370 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr18_-_46212595 0.363 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr7_+_127233044 0.361 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr6_-_122340200 0.355 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr18_-_88894203 0.353 ENSMUST00000123826.1
Socs6
suppressor of cytokine signaling 6
chr4_+_85205417 0.340 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr11_+_46055973 0.331 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr10_+_79988584 0.329 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr12_+_21111778 0.328 ENSMUST00000050990.9
Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chrX_+_151198078 0.327 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
Wnk3


WNK lysine deficient protein kinase 3


chr12_-_41485751 0.324 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr13_-_54687696 0.323 ENSMUST00000177950.1
ENSMUST00000146931.1
Rnf44

ring finger protein 44

chr7_+_27591513 0.322 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr9_+_90163057 0.321 ENSMUST00000113059.1
ENSMUST00000167122.1
Adamts7

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7

chr12_+_53248677 0.314 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr12_+_84996309 0.309 ENSMUST00000168977.1
ENSMUST00000021670.8
Ylpm1

YLP motif containing 1

chr8_+_35587780 0.307 ENSMUST00000037666.5
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr17_+_53566971 0.305 ENSMUST00000000724.8
Kat2b
K(lysine) acetyltransferase 2B
chr4_-_118179628 0.296 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr9_+_90162978 0.294 ENSMUST00000113060.1
Adamts7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr5_-_138155694 0.292 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr7_+_27591705 0.291 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr1_+_88227005 0.291 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr8_+_107436355 0.287 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr2_-_6722187 0.286 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr1_-_105659008 0.277 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr15_-_79328154 0.276 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chr2_+_163658370 0.275 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr1_+_131153175 0.274 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
Eif2d


eukaryotic translation initiation factor 2D


chr17_-_34031644 0.273 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr1_-_93101825 0.268 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr10_-_13388830 0.261 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr5_-_62765618 0.258 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr13_-_119408985 0.258 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr12_-_83597140 0.256 ENSMUST00000048319.4
Zfyve1
zinc finger, FYVE domain containing 1
chr11_+_114851814 0.254 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
Gprc5c


G protein-coupled receptor, family C, group 5, member C


chr3_-_89998656 0.253 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr10_-_13388753 0.251 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr6_+_83057844 0.244 ENSMUST00000077502.2
Dqx1
DEAQ RNA-dependent ATPase
chr13_-_41358990 0.243 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr9_-_103761820 0.241 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr5_+_34549595 0.240 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr5_-_122050102 0.232 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr13_+_109903089 0.228 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_-_122340525 0.228 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr15_-_79328201 0.226 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr2_+_27079371 0.221 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr5_+_148265265 0.218 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr17_+_20570362 0.215 ENSMUST00000095633.3
Gm5145
predicted pseudogene 5145
chr13_-_102906046 0.214 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr9_-_45984816 0.213 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr3_-_95106779 0.212 ENSMUST00000005768.7
ENSMUST00000107232.2
ENSMUST00000107236.2
Pip5k1a


phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha


chr1_-_12991109 0.208 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr9_-_35267746 0.205 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b



family with sequence similarity 118, member B



chr11_-_78497458 0.194 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr2_-_165034770 0.191 ENSMUST00000122070.1
ENSMUST00000121377.1
Ncoa5

nuclear receptor coactivator 5

chr14_+_21499770 0.187 ENSMUST00000182855.1
ENSMUST00000069648.7
ENSMUST00000182405.1
Kat6b


K(lysine) acetyltransferase 6B


chr16_+_87698904 0.186 ENSMUST00000026703.5
Bach1
BTB and CNC homology 1
chr17_-_51810866 0.180 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr19_-_32466575 0.176 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr14_+_61599493 0.172 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr10_-_61979073 0.170 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr19_-_5894100 0.166 ENSMUST00000055911.4
Tigd3
tigger transposable element derived 3
chr12_-_12941827 0.160 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_160731684 0.158 ENSMUST00000174885.1
ENSMUST00000109462.1
Plcg1

phospholipase C, gamma 1

chr12_-_23968845 0.156 ENSMUST00000171153.1
Gm17330
predicted gene, 17330
chr4_-_91376490 0.155 ENSMUST00000107124.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_+_69989466 0.153 ENSMUST00000034754.5
ENSMUST00000085393.6
ENSMUST00000117450.1
Bnip2


BCL2/adenovirus E1B interacting protein 2


chr15_-_50890396 0.153 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr7_+_126760591 0.147 ENSMUST00000091328.2
Mapk3
mitogen-activated protein kinase 3
chr7_-_13009795 0.147 ENSMUST00000051390.7
ENSMUST00000172240.1
Zbtb45

zinc finger and BTB domain containing 45

chr12_-_51829525 0.147 ENSMUST00000179265.1
ENSMUST00000042052.8
Hectd1

HECT domain containing 1

chrX_-_7572843 0.144 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr19_-_10604258 0.137 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr14_+_50924968 0.137 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
Apex1


apurinic/apyrimidinic endonuclease 1


chr17_+_34031787 0.135 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.7 2.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.4 2.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.4 1.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3 1.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 0.8 GO:0007403 glial cell fate determination(GO:0007403)
0.2 0.5 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662)
0.2 0.5 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 4.0 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.2 0.9 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 1.8 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 1.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 2.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.6 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228) contact inhibition(GO:0060242)
0.2 0.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 1.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 1.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 0.5 GO:0035973 aggrephagy(GO:0035973)
0.2 0.5 GO:1903334 positive regulation of protein folding(GO:1903334)
0.2 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 1.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 1.7 GO:0060539 diaphragm development(GO:0060539)
0.1 1.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 2.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.5 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 1.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.5 GO:0042117 monocyte activation(GO:0042117)
0.1 0.7 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.6 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.9 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.7 GO:0031424 keratinization(GO:0031424)
0.1 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 2.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.5 GO:0009409 response to cold(GO:0009409)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.7 GO:0045056 transcytosis(GO:0045056)
0.0 1.0 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 1.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0071707 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.8 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0071494 pyrimidine dimer repair(GO:0006290) cellular response to UV-C(GO:0071494)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.6 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.7 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.3 1.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.3 1.1 GO:0008623 CHRAC(GO:0008623)
0.2 0.9 GO:1990032 parallel fiber(GO:1990032)
0.2 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 1.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 1.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.7 GO:0001533 cornified envelope(GO:0001533)
0.1 2.6 GO:0071564 npBAF complex(GO:0071564)
0.1 1.3 GO:0001739 sex chromatin(GO:0001739)
0.1 0.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.3 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.0 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.6 GO:0031105 septin complex(GO:0031105)
0.0 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 5.6 GO:0005813 centrosome(GO:0005813)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 7.4 GO:0070411 I-SMAD binding(GO:0070411)
0.4 1.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 2.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 1.3 GO:0050436 microfibril binding(GO:0050436)
0.2 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.2 0.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 1.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.6 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.1 1.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.3 GO:0005118 sevenless binding(GO:0005118)
0.1 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.2 GO:0035198 miRNA binding(GO:0035198)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 7.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0051020 GTPase binding(GO:0051020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.0 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.8 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.6 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_MYC_PATHWAY C-MYC pathway
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 2.1 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.1 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.2 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 1.2 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.7 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.1 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.8 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.5 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.2 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events