Motif ID: Tead1

Z-value: 0.321


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112679314_112679325-0.163.6e-01Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_46099752 1.619 ENSMUST00000180081.1
 Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr11_-_100970887 1.262 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr15_+_6386598 1.245 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
 Dab2




disabled 2, mitogen-responsive phosphoprotein




chr10_+_28074813 1.147 ENSMUST00000166468.1
 Ptprk
protein tyrosine phosphatase, receptor type, K
chr17_+_3397189 1.055 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr19_-_57197556 1.007 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chr19_-_57197377 0.992 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197435 0.973 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197496 0.972 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr7_-_34133215 0.845 ENSMUST00000038537.8
 Wtip
WT1-interacting protein
chr6_+_17306335 0.832 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr2_+_19658055 0.816 ENSMUST00000052168.4
 Otud1
OTU domain containing 1
chr17_+_86167777 0.783 ENSMUST00000097275.2
 Prkce
protein kinase C, epsilon
chr11_-_32222233 0.679 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr8_-_105966038 0.663 ENSMUST00000116429.2
ENSMUST00000034370.9
 Slc12a4

solute carrier family 12, member 4

chr2_+_156775409 0.607 ENSMUST00000088552.6
 Myl9
myosin, light polypeptide 9, regulatory
chr10_+_24595623 0.594 ENSMUST00000176228.1
ENSMUST00000129142.1
 Ctgf

connective tissue growth factor

chr15_+_78842632 0.554 ENSMUST00000059619.1
 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr1_-_87394721 0.532 ENSMUST00000113212.3
 Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr6_-_128124312 0.499 ENSMUST00000127105.1
 Tspan9
tetraspanin 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 2.2 GO:0010107 potassium ion import(GO:0010107)
0.2 1.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 1.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 1.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 1.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 0.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.7 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.3 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 1.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 1.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 1.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 0.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_IL27_PATHWAY IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport