Motif ID: Tead3_Tead4

Z-value: 1.195

Transcription factors associated with Tead3_Tead4:

Gene SymbolEntrez IDGene Name
Tead3 ENSMUSG00000002249.11 Tead3
Tead4 ENSMUSG00000030353.9 Tead4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead3mm10_v2_chr17_-_28350747_283508200.492.0e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tead3_Tead4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_43558386 6.067 ENSMUST00000130353.1
Tln1
talin 1
chr1_+_43730593 5.930 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr10_+_24595434 5.589 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr10_+_24595623 5.174 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr7_-_132813799 4.922 ENSMUST00000097998.2
Fam53b
family with sequence similarity 53, member B
chr10_+_28074813 4.470 ENSMUST00000166468.1
Ptprk
protein tyrosine phosphatase, receptor type, K
chr11_-_100970887 4.355 ENSMUST00000060792.5
Ptrf
polymerase I and transcript release factor
chr15_+_6386598 3.681 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr6_+_121300227 3.673 ENSMUST00000064580.7
Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr7_-_132813715 3.469 ENSMUST00000134946.1
Fam53b
family with sequence similarity 53, member B
chr17_-_35702297 2.880 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr7_+_51880312 2.698 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr11_-_32222233 2.643 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr17_+_78508063 2.585 ENSMUST00000024880.9
Vit
vitrin
chr10_-_42276688 2.481 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3

forkhead box O3

chr9_+_69454066 2.471 ENSMUST00000134907.1
Anxa2
annexin A2
chr7_-_19698206 2.361 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr17_+_3397189 2.277 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr17_-_35702040 2.262 ENSMUST00000166980.2
ENSMUST00000145900.1
Ddr1

discoidin domain receptor family, member 1

chr10_-_42276744 2.222 ENSMUST00000105502.1
ENSMUST00000105501.1
Foxo3

forkhead box O3

chr17_-_35701937 2.191 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr9_+_50752758 2.190 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr3_-_57575760 2.135 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr18_-_35722330 2.133 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr15_+_78842632 2.056 ENSMUST00000059619.1
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chrX_-_142306170 1.960 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr7_+_114745685 1.919 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr16_-_36784924 1.901 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr1_+_45311538 1.846 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr8_-_105966038 1.846 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr2_+_20519776 1.801 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr10_-_78591945 1.799 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr13_-_113046357 1.794 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr3_-_145649970 1.746 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr1_+_74391479 1.738 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_+_69453620 1.712 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr4_-_154636831 1.710 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr11_-_115813621 1.656 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr12_-_98737405 1.652 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr9_-_79718631 1.651 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr7_-_27181149 1.636 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr4_+_48045144 1.617 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr15_+_25773985 1.562 ENSMUST00000125667.1
Myo10
myosin X
chr2_-_113758638 1.505 ENSMUST00000099575.3
Grem1
gremlin 1
chr12_+_75308308 1.504 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr1_+_104768510 1.482 ENSMUST00000062528.8
Cdh20
cadherin 20
chr7_-_120202104 1.476 ENSMUST00000033198.5
Crym
crystallin, mu
chr5_+_66968416 1.470 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr19_-_42129043 1.468 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr2_-_181671622 1.440 ENSMUST00000054491.5
Sox18
SRY-box containing gene 18
chr9_-_79718518 1.434 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr3_-_57575907 1.423 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr1_+_42229726 1.420 ENSMUST00000066196.1
Gm9915
predicted gene 9915
chr13_-_83729544 1.413 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr1_+_51289106 1.402 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr10_+_126978690 1.380 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_+_63812447 1.360 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr6_-_35308110 1.357 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr7_-_19698383 1.354 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr9_-_96752822 1.337 ENSMUST00000152594.1
Zbtb38
zinc finger and BTB domain containing 38
chr16_-_55283237 1.319 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr17_-_28350747 1.318 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr6_-_37442095 1.298 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr2_-_164857542 1.294 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr11_+_98412461 1.289 ENSMUST00000058295.5
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr9_+_44101722 1.274 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
Mfrp


membrane-type frizzled-related protein


chr18_-_78206408 1.264 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr2_+_19658055 1.236 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr9_-_79718720 1.236 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr6_-_134566913 1.230 ENSMUST00000032322.8
Lrp6
low density lipoprotein receptor-related protein 6
chr12_-_80112998 1.223 ENSMUST00000165114.1
ENSMUST00000021552.1
Zfp36l1

zinc finger protein 36, C3H type-like 1

chr2_-_148443543 1.222 ENSMUST00000099269.3
Cd93
CD93 antigen
chr1_+_12692430 1.213 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr13_-_84064772 1.210 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr6_+_29694204 1.204 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr17_-_28350600 1.162 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr10_-_127288851 1.144 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr5_+_66968559 1.130 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr4_-_88033328 1.123 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_+_154237525 1.116 ENSMUST00000152159.1
Megf6
multiple EGF-like-domains 6
chr5_+_64812336 1.094 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chrX_+_101254528 1.084 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr7_-_132317198 1.079 ENSMUST00000080215.5
Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_-_137314175 1.070 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chr1_-_87394721 1.068 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr11_+_112782182 1.046 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr19_-_42128982 0.996 ENSMUST00000161873.1
Avpi1
arginine vasopressin-induced 1
chr6_+_80018877 0.995 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr14_+_46882854 0.976 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chr17_+_88626569 0.962 ENSMUST00000150023.1
Ston1
stonin 1
chr11_+_100415697 0.950 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr17_+_88626549 0.942 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chr10_-_127288999 0.937 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr3_-_84220853 0.915 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr2_-_164857671 0.906 ENSMUST00000059954.7
Pltp
phospholipid transfer protein
chr4_+_94739276 0.901 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr14_+_101729907 0.891 ENSMUST00000100337.3
Lmo7
LIM domain only 7
chr7_-_115824699 0.891 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr15_+_101266839 0.885 ENSMUST00000023779.6
Nr4a1
nuclear receptor subfamily 4, group A, member 1
chr9_-_58158498 0.881 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr6_+_80019008 0.877 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr3_-_103737995 0.873 ENSMUST00000029440.8
Olfml3
olfactomedin-like 3
chr6_+_17306335 0.826 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr16_+_43363855 0.825 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr18_+_60911757 0.824 ENSMUST00000040359.5
Arsi
arylsulfatase i
chr14_+_70890099 0.821 ENSMUST00000022699.8
Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr2_-_18048784 0.818 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr1_+_165769392 0.806 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chr12_+_76533540 0.800 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_-_120120138 0.788 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr11_-_100939357 0.787 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr12_-_76709997 0.782 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr6_+_29735667 0.782 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr11_-_100939457 0.775 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr11_+_100415722 0.772 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chr6_+_29433248 0.767 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr15_-_103366763 0.765 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr11_+_62077018 0.764 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr19_-_4439388 0.762 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod

ras homolog gene family, member D

chr8_+_128685654 0.759 ENSMUST00000090006.5
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr4_-_4138432 0.755 ENSMUST00000070375.7
Penk
preproenkephalin
chr4_+_98546710 0.736 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr1_-_82291370 0.734 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr17_-_35697971 0.734 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr14_+_55094835 0.733 ENSMUST00000050575.7
Thtpa
thiamine triphosphatase
chr7_-_65370908 0.731 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr11_-_100939540 0.728 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr4_+_133176336 0.718 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr11_-_54028090 0.717 ENSMUST00000020586.6
Slc22a4
solute carrier family 22 (organic cation transporter), member 4
chr5_-_24601961 0.712 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_44519405 0.711 ENSMUST00000101327.2
Rnf145
ring finger protein 145
chr4_+_97777780 0.711 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr4_+_98546919 0.709 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chrX_-_74246364 0.709 ENSMUST00000130007.1
Flna
filamin, alpha
chr6_+_34598530 0.702 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr9_+_109095427 0.697 ENSMUST00000072093.6
Plxnb1
plexin B1
chr7_+_19368498 0.685 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr16_+_43364145 0.682 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_-_128704978 0.681 ENSMUST00000026416.7
ENSMUST00000026415.7
Cdk2

cyclin-dependent kinase 2

chr3_-_116423930 0.664 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chrX_+_56454871 0.661 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr4_+_49059256 0.658 ENSMUST00000076670.2
E130309F12Rik
RIKEN cDNA E130309F12 gene
chr3_-_135691512 0.653 ENSMUST00000029812.7
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr7_-_31054815 0.648 ENSMUST00000071697.4
ENSMUST00000108110.3
Fxyd1

FXYD domain-containing ion transport regulator 1

chr9_-_91365778 0.642 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr4_-_132398199 0.626 ENSMUST00000136711.1
ENSMUST00000084249.4
Phactr4

phosphatase and actin regulator 4

chr11_-_115808068 0.625 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chr1_+_169928648 0.624 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr6_+_34598500 0.623 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr3_-_116424007 0.622 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr17_-_57000018 0.614 ENSMUST00000002740.2
Pspn
persephin
chr1_-_136234113 0.605 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr8_+_110266960 0.603 ENSMUST00000043141.6
Hydin
HYDIN, axonemal central pair apparatus protein
chr8_-_11678728 0.592 ENSMUST00000033906.4
1700016D06Rik
RIKEN cDNA 1700016D06 gene
chr19_+_42045792 0.584 ENSMUST00000172244.1
ENSMUST00000081714.4
Hoga1

4-hydroxy-2-oxoglutarate aldolase 1

chr19_+_46305682 0.575 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_+_156840077 0.571 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr5_+_24426831 0.548 ENSMUST00000155598.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr2_+_164497518 0.545 ENSMUST00000103101.4
ENSMUST00000117066.1
Pigt

phosphatidylinositol glycan anchor biosynthesis, class T

chr1_+_156558844 0.544 ENSMUST00000166172.2
ENSMUST00000027888.6
Abl2

v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)

chr9_+_96258697 0.523 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr5_+_24394388 0.520 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr6_-_128124312 0.516 ENSMUST00000127105.1
Tspan9
tetraspanin 9
chr13_-_81570640 0.514 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr11_+_78188422 0.504 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chr1_-_157256682 0.503 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr11_+_78188806 0.503 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chrX_-_74246534 0.500 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr11_+_78188737 0.497 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr2_+_25456830 0.496 ENSMUST00000114265.2
ENSMUST00000102918.2
Clic3

chloride intracellular channel 3

chr17_-_71002488 0.485 ENSMUST00000148960.1
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr6_+_29433131 0.483 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr2_+_91457501 0.472 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr7_-_109616548 0.468 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr19_-_12765447 0.467 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr9_-_91365756 0.466 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chr13_-_77131276 0.462 ENSMUST00000159300.1
Ankrd32
ankyrin repeat domain 32
chr10_+_5593718 0.461 ENSMUST00000051809.8
Myct1
myc target 1
chr9_+_109096659 0.458 ENSMUST00000130366.1
Plxnb1
plexin B1
chr7_+_128523576 0.450 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr17_+_47593516 0.450 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr6_+_48593927 0.450 ENSMUST00000135151.1
Repin1
replication initiator 1
chr17_+_47593444 0.447 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr9_+_35421541 0.443 ENSMUST00000119129.2
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr5_+_136991624 0.440 ENSMUST00000127100.1
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_-_104816696 0.436 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr11_-_101170327 0.434 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr3_-_101110278 0.432 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr19_-_5683873 0.425 ENSMUST00000141577.1
Pcnxl3
pecanex-like 3 (Drosophila)
chr14_+_30879257 0.416 ENSMUST00000040715.6
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr5_+_137630116 0.411 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr9_-_59036387 0.410 ENSMUST00000068664.5
Neo1
neogenin
chr1_-_72874877 0.409 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr15_-_42676967 0.408 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr2_-_39190687 0.407 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr4_-_118409219 0.406 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr11_+_87581041 0.406 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
Sept4


septin 4


chr10_-_58675631 0.398 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr17_-_47834682 0.395 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr10_-_13324250 0.387 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.8 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.2 3.7 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.8 4.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.8 0.8 GO:0061113 pancreas morphogenesis(GO:0061113)
0.7 5.9 GO:0070314 G1 to G0 transition(GO:0070314)
0.7 5.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.7 8.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 4.7 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.6 3.7 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.6 2.3 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.5 2.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.5 1.6 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.5 1.0 GO:0072034 renal vesicle induction(GO:0072034)
0.5 3.6 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.5 1.5 GO:1903011 regulation of osteoclast proliferation(GO:0090289) negative regulation of bone development(GO:1903011)
0.5 1.4 GO:0048866 stem cell fate specification(GO:0048866)
0.5 3.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.4 4.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 1.7 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.4 1.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 1.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.4 0.4 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.4 1.2 GO:0061324 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.4 1.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.4 1.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.4 1.9 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.4 1.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 2.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 1.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 1.5 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 1.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 1.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 0.8 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.2 0.7 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.7 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2 1.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 1.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 2.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 0.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 2.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.2 8.3 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 0.8 GO:1903598 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) positive regulation of gap junction assembly(GO:1903598) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2 0.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 0.6 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.8 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 1.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.6 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.8 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.1 0.7 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.1 0.4 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 1.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.7 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.7 GO:0015879 carnitine transport(GO:0015879)
0.1 1.9 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.4 GO:0008272 sulfate transport(GO:0008272)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.6 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.1 1.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.4 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.4 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.6 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 3.3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.7 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.2 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.2 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.8 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 0.6 GO:0002467 germinal center formation(GO:0002467)
0.0 1.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 1.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.7 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.3 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.6 GO:0060438 trachea development(GO:0060438)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0070309 notochord formation(GO:0014028) lens fiber cell morphogenesis(GO:0070309) pericyte cell differentiation(GO:1904238)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.6 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 1.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.3 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.1 GO:0042307 positive regulation of protein import into nucleus(GO:0042307)
0.0 2.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 1.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.5 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.8 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:1901184 regulation of ERBB signaling pathway(GO:1901184)
0.0 1.3 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.4 4.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.2 3.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.2 1.2 GO:0031012 extracellular matrix(GO:0031012)
0.9 3.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 1.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.4 2.2 GO:0097512 cardiac myofibril(GO:0097512)
0.3 4.7 GO:0031045 dense core granule(GO:0031045)
0.3 0.8 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.2 0.7 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.2 GO:0031523 Myb complex(GO:0031523)
0.2 0.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 10.4 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.2 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 1.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.3 GO:0043219 lateral loop(GO:0043219)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.8 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.6 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0098858 actin-based cell projection(GO:0098858)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 8.7 GO:0001726 ruffle(GO:0001726)
0.0 2.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 2.0 GO:0016235 aggresome(GO:0016235)
0.0 2.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 7.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 15.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.6 GO:0044447 axoneme part(GO:0044447)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.0 GO:0016528 sarcoplasm(GO:0016528)
0.0 1.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.2 3.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.0 4.2 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.9 8.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 6.1 GO:0030274 LIM domain binding(GO:0030274)
0.6 1.9 GO:0042936 dipeptide transporter activity(GO:0042936)
0.6 13.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 1.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.4 1.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.4 1.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 3.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 3.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 0.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 1.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 0.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.3 2.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 0.8 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 2.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.2 4.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.7 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.5 GO:0043184 BMP binding(GO:0036122) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 0.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 1.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.8 GO:0005113 patched binding(GO:0005113)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 6.1 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 1.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 1.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.5 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.9 GO:0017022 myosin binding(GO:0017022)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.2 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 17.5 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.2 1.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.2 5.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.2 3.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.1 ST_STAT3_PATHWAY STAT3 Pathway
0.1 6.2 NABA_COLLAGENS Genes encoding collagen proteins
0.1 3.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 3.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.1 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 1.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 3.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 0.7 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 2.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 2.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.1 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 5.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 6.1 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 4.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.2 2.7 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 3.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 4.4 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 6.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.8 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.3 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.0 REACTOME_PI3K_AKT_ACTIVATION Genes involved in PI3K/AKT activation
0.1 1.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.1 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 4.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 5.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization