Motif ID: Tfap2b

Z-value: 0.827


Transcription factors associated with Tfap2b:

Gene SymbolEntrez IDGene Name
Tfap2b ENSMUSG00000025927.7 Tfap2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2bmm10_v2_chr1_+_19212054_19212106-0.563.5e-04Click!


Activity profile for motif Tfap2b.

activity profile for motif Tfap2b


Sorted Z-values histogram for motif Tfap2b

Sorted Z-values for motif Tfap2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_5740885 5.817 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr2_+_91945703 5.182 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr12_+_70825492 4.027 ENSMUST00000057859.7
Frmd6
FERM domain containing 6
chr4_+_48045144 3.081 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr18_+_64340225 3.024 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr1_-_14310198 3.010 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr2_+_153031852 2.271 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr17_+_83215271 2.258 ENSMUST00000170794.1
Pkdcc
protein kinase domain containing, cytoplasmic
chr13_+_49187485 2.133 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr12_+_84009481 2.049 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr17_+_86963279 1.994 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr11_+_35121126 1.950 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr1_-_98095596 1.834 ENSMUST00000058762.8
ENSMUST00000097625.3
Pam

peptidylglycine alpha-amidating monooxygenase

chr7_+_27607997 1.801 ENSMUST00000142365.1
Akt2
thymoma viral proto-oncogene 2
chr9_-_40455670 1.682 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr8_+_84723003 1.646 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr4_+_8690399 1.641 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr4_-_22488296 1.617 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr7_+_27607748 1.597 ENSMUST00000136962.1
Akt2
thymoma viral proto-oncogene 2
chr2_+_59612034 1.523 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr17_-_35700520 1.413 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr2_+_133552159 1.332 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr6_-_37299950 1.332 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr1_-_56978534 1.260 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr19_-_42752710 1.258 ENSMUST00000076505.3
Pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chrX_+_7722267 1.257 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr4_-_133967235 1.248 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr15_-_72034202 1.240 ENSMUST00000159993.1
Col22a1
collagen, type XXII, alpha 1
chr1_+_55406163 1.229 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chrX_+_7723278 1.191 ENSMUST00000144148.1
Wdr45
WD repeat domain 45
chr8_-_111910171 1.150 ENSMUST00000034430.4
Chst5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr6_-_97487801 1.125 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr17_+_86963077 1.083 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr4_-_133967296 1.050 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr14_+_61172966 1.048 ENSMUST00000121091.1
Sacs
sacsin
chr18_+_36281069 1.039 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr2_-_92024502 1.028 ENSMUST00000028663.4
Creb3l1
cAMP responsive element binding protein 3-like 1
chr9_+_54699514 1.021 ENSMUST00000154690.1
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr4_+_155839724 0.993 ENSMUST00000030947.3
Mxra8
matrix-remodelling associated 8
chr2_+_25262589 0.989 ENSMUST00000114336.3
Tprn
taperin
chr10_-_81349085 0.985 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr4_+_109978004 0.965 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr13_+_44731281 0.957 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_-_173276526 0.954 ENSMUST00000036248.6
Pmepa1
prostate transmembrane protein, androgen induced 1
chr11_+_94327984 0.927 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chrX_+_73757069 0.923 ENSMUST00000002079.6
Plxnb3
plexin B3
chr7_+_45526330 0.915 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr9_+_54699548 0.901 ENSMUST00000070070.7
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr4_+_133176336 0.900 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr2_-_173276144 0.895 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr15_-_75747922 0.871 ENSMUST00000062002.4
Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr1_-_56972437 0.870 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr3_-_116424007 0.837 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr11_-_75454656 0.829 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr3_-_116423930 0.824 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr15_+_81987835 0.802 ENSMUST00000165777.1
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr4_-_133967893 0.801 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr1_-_136234113 0.796 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr6_-_39725193 0.772 ENSMUST00000101497.3
Braf
Braf transforming gene
chr11_+_99041237 0.770 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chr8_+_79028317 0.750 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr11_+_94328242 0.739 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr7_-_80232752 0.731 ENSMUST00000065163.8
Cib1
calcium and integrin binding 1 (calmyrin)
chr7_+_28180226 0.728 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_77348272 0.728 ENSMUST00000181283.1
Ssh2
slingshot homolog 2 (Drosophila)
chr7_-_93081027 0.727 ENSMUST00000098303.1
Gm9934
predicted gene 9934
chr7_+_78578830 0.719 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr6_+_85187438 0.719 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr10_-_127211528 0.708 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_-_80232556 0.705 ENSMUST00000071457.5
Cib1
calcium and integrin binding 1 (calmyrin)
chr5_-_121836852 0.700 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr18_-_60713389 0.685 ENSMUST00000169273.1
Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_36105271 0.685 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr14_-_67715585 0.681 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr14_+_21499770 0.673 ENSMUST00000182855.1
ENSMUST00000069648.7
ENSMUST00000182405.1
Kat6b


K(lysine) acetyltransferase 6B


chr7_+_28180272 0.660 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr1_-_143702832 0.651 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr2_-_5942740 0.645 ENSMUST00000026924.5
ENSMUST00000095147.2
ENSMUST00000169865.1
Dhtkd1


dehydrogenase E1 and transketolase domain containing 1


chr13_+_40917626 0.640 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chrX_+_159627534 0.636 ENSMUST00000073094.3
Sh3kbp1
SH3-domain kinase binding protein 1
chr11_-_100414829 0.635 ENSMUST00000066489.6
Leprel4
leprecan-like 4
chr5_-_121836810 0.633 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr3_-_132950043 0.623 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
Npnt




nephronectin




chr18_+_36559972 0.617 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr4_-_133967953 0.578 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr19_+_6975048 0.576 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_156065738 0.562 ENSMUST00000137966.1
Spag4
sperm associated antigen 4
chr4_+_43669610 0.549 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chr14_-_31830402 0.545 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr17_-_46282991 0.545 ENSMUST00000180283.1
ENSMUST00000012440.6
ENSMUST00000164342.2
Tjap1


tight junction associated protein 1


chr11_-_75178792 0.537 ENSMUST00000071562.2
Ovca2
candidate tumor suppressor in ovarian cancer 2
chr2_-_93957040 0.534 ENSMUST00000148314.2
Gm13889
predicted gene 13889
chr11_-_101170327 0.525 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr3_+_144570409 0.522 ENSMUST00000082437.3
Sep15
selenoprotein
chr15_-_98871175 0.518 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr9_-_122862128 0.511 ENSMUST00000056467.7
Zfp445
zinc finger protein 445
chr5_+_30913398 0.503 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr7_+_45705088 0.502 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr7_+_45705518 0.490 ENSMUST00000107740.1
ENSMUST00000107741.1
Dbp

D site albumin promoter binding protein

chr10_-_117148474 0.486 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr1_+_74791516 0.482 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr3_+_144570687 0.474 ENSMUST00000106211.1
Sep15
selenoprotein
chr19_+_38055002 0.474 ENSMUST00000096096.4
ENSMUST00000116506.1
ENSMUST00000169673.1
Cep55


centrosomal protein 55


chr7_-_66689474 0.470 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr2_+_28513105 0.461 ENSMUST00000135803.1
Ralgds
ral guanine nucleotide dissociation stimulator
chr15_+_7129557 0.457 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chrX_+_99975570 0.456 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr11_+_102189620 0.440 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr11_-_94242701 0.432 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr7_-_63938862 0.428 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr7_-_45526146 0.419 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr14_-_55643523 0.415 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr16_+_24448082 0.414 ENSMUST00000078988.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr17_-_70849644 0.404 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr12_-_76709997 0.398 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr11_+_82781108 0.392 ENSMUST00000092849.5
ENSMUST00000021039.5
ENSMUST00000080461.5
ENSMUST00000173347.1
ENSMUST00000173727.1
ENSMUST00000173009.1
ENSMUST00000131537.2
ENSMUST00000173722.1
Lig3







ligase III, DNA, ATP-dependent







chr16_-_20425881 0.390 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_+_156065180 0.388 ENSMUST00000038860.5
Spag4
sperm associated antigen 4
chr10_-_59951753 0.381 ENSMUST00000020308.3
Ddit4
DNA-damage-inducible transcript 4
chr17_+_73107982 0.373 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1


lysocardiolipin acyltransferase 1


chr2_-_11502090 0.363 ENSMUST00000179584.1
ENSMUST00000170196.2
ENSMUST00000171188.2
ENSMUST00000114845.3
ENSMUST00000114844.1
ENSMUST00000100411.2
Pfkfb3





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3





chr9_-_52168111 0.357 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chr19_+_3767953 0.357 ENSMUST00000113970.1
Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr11_-_96977660 0.350 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2

Sp2 transcription factor

chr5_+_52582320 0.344 ENSMUST00000177881.1
Gm5866
predicted gene 5866
chr13_-_9764865 0.334 ENSMUST00000128658.1
Zmynd11
zinc finger, MYND domain containing 11
chr11_-_106920359 0.334 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr9_-_54647199 0.333 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_70255329 0.330 ENSMUST00000108574.2
ENSMUST00000000329.2
Alox12

arachidonate 12-lipoxygenase

chr2_+_18064645 0.326 ENSMUST00000114680.2
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_96872221 0.325 ENSMUST00000181489.1
Gm5101
predicted gene 5101
chr4_+_127126034 0.324 ENSMUST00000094712.4
Gm12942
predicted gene 12942
chrX_+_159627265 0.321 ENSMUST00000112456.2
Sh3kbp1
SH3-domain kinase binding protein 1
chr14_-_55643251 0.320 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr4_+_43875524 0.318 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr3_-_137981523 0.308 ENSMUST00000136613.1
ENSMUST00000029806.6
Dapp1

dual adaptor for phosphotyrosine and 3-phosphoinositides 1

chr11_-_58168467 0.308 ENSMUST00000172035.1
ENSMUST00000035604.6
ENSMUST00000102711.2
Gemin5


gem (nuclear organelle) associated protein 5


chr14_-_55643720 0.294 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr5_-_88675613 0.292 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr10_+_7681197 0.290 ENSMUST00000165952.1
Lats1
large tumor suppressor
chr1_-_63114255 0.287 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
Ino80d



INO80 complex subunit D



chr5_-_37824580 0.286 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr11_-_3774706 0.285 ENSMUST00000155197.1
Osbp2
oxysterol binding protein 2
chr17_-_32284715 0.285 ENSMUST00000127893.1
Brd4
bromodomain containing 4
chr19_+_6364557 0.284 ENSMUST00000155973.1
Sf1
splicing factor 1
chr13_+_44731265 0.280 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr9_-_99436749 0.276 ENSMUST00000122384.1
Mras
muscle and microspikes RAS
chr19_-_3282958 0.270 ENSMUST00000119292.1
ENSMUST00000025751.3
Ighmbp2

immunoglobulin mu binding protein 2

chr2_+_18064564 0.269 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr14_-_55643800 0.268 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr16_+_3744089 0.266 ENSMUST00000023176.4
Zfp263
zinc finger protein 263
chr1_+_34160253 0.261 ENSMUST00000183302.1
Dst
dystonin
chr5_+_28165690 0.254 ENSMUST00000036177.7
En2
engrailed 2
chr5_-_88676135 0.251 ENSMUST00000078945.5
Grsf1
G-rich RNA sequence binding factor 1
chr9_+_119402444 0.247 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chrX_+_94724569 0.244 ENSMUST00000101388.2
Zxdb
zinc finger, X-linked, duplicated B
chr2_+_119174483 0.239 ENSMUST00000069711.2
Gm14137
predicted gene 14137
chr3_+_152396664 0.236 ENSMUST00000089982.4
ENSMUST00000106101.1
Zzz3

zinc finger, ZZ domain containing 3

chr9_+_62342059 0.234 ENSMUST00000135395.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr10_-_123076367 0.234 ENSMUST00000073792.3
ENSMUST00000170935.1
ENSMUST00000037557.7
Mon2


MON2 homolog (yeast)


chr11_-_61855026 0.224 ENSMUST00000004920.3
Ulk2
unc-51 like kinase 2
chr18_-_46525940 0.217 ENSMUST00000036226.5
Fem1c
fem-1 homolog c (C.elegans)
chr9_+_62342449 0.210 ENSMUST00000156461.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr2_-_174438996 0.208 ENSMUST00000016400.8
Ctsz
cathepsin Z
chr16_+_23609895 0.202 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr14_+_25842146 0.197 ENSMUST00000022416.8
Anxa11
annexin A11
chr8_-_33385470 0.194 ENSMUST00000033991.6
ENSMUST00000033990.5
Wrn

Werner syndrome homolog (human)

chr15_-_102257306 0.193 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr11_-_5741141 0.190 ENSMUST00000140922.1
ENSMUST00000093362.5
Urgcp

upregulator of cell proliferation

chr12_+_102128718 0.188 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_+_155956537 0.186 ENSMUST00000109619.2
ENSMUST00000039994.7
ENSMUST00000094421.4
ENSMUST00000151569.1
ENSMUST00000109618.1
Cep250




centrosomal protein 250




chr13_+_12702362 0.184 ENSMUST00000104944.2
Gm2399
predicted gene 2399
chr8_+_105170668 0.181 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr3_-_30969399 0.177 ENSMUST00000177992.1
ENSMUST00000129817.2
ENSMUST00000168645.1
ENSMUST00000108255.1
ENSMUST00000064718.5
ENSMUST00000099163.3
Phc3





polyhomeotic-like 3 (Drosophila)





chrX_+_151047170 0.173 ENSMUST00000026296.7
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr10_-_61452658 0.171 ENSMUST00000167087.1
ENSMUST00000020288.7
Eif4ebp2

eukaryotic translation initiation factor 4E binding protein 2

chr14_+_45351473 0.169 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chr18_+_60774510 0.165 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr10_+_82859198 0.163 ENSMUST00000020484.6
Txnrd1
thioredoxin reductase 1
chr15_-_99370427 0.162 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
Fmnl3


formin-like 3


chr18_+_60774675 0.154 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr19_+_3767397 0.152 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chr5_-_137962955 0.145 ENSMUST00000077119.6
Gjc3
gap junction protein, gamma 3
chr5_-_115158169 0.140 ENSMUST00000053271.5
ENSMUST00000112121.1
Mlec

malectin

chr2_-_11502067 0.133 ENSMUST00000028114.6
ENSMUST00000049849.6
Pfkfb3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

chr9_+_37613806 0.128 ENSMUST00000002007.3
Siae
sialic acid acetylesterase
chr7_-_80371197 0.126 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chr2_-_30830333 0.120 ENSMUST00000041726.3
Asb6
ankyrin repeat and SOCS box-containing 6
chr2_+_30237680 0.116 ENSMUST00000113654.1
ENSMUST00000095078.2
Lrrc8a

leucine rich repeat containing 8A

chr9_-_57262591 0.110 ENSMUST00000034846.5
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr13_+_37826225 0.107 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr9_-_99436687 0.107 ENSMUST00000035045.8
Mras
muscle and microspikes RAS
chr4_-_133753611 0.106 ENSMUST00000145664.2
ENSMUST00000105897.3
Arid1a

AT rich interactive domain 1A (SWI-like)

chr19_-_53038534 0.102 ENSMUST00000183274.1
ENSMUST00000182097.1
ENSMUST00000069988.8
Xpnpep1


X-prolyl aminopeptidase (aminopeptidase P) 1, soluble


chr14_+_67716262 0.102 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr19_+_6363719 0.100 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr6_+_125009665 0.099 ENSMUST00000046064.10
ENSMUST00000152752.1
ENSMUST00000088308.3
ENSMUST00000112425.1
ENSMUST00000084275.5
Zfp384




zinc finger protein 384




chr4_+_10874498 0.099 ENSMUST00000080517.7
ENSMUST00000101504.2
2610301B20Rik

RIKEN cDNA 2610301B20 gene

chr12_+_84316830 0.096 ENSMUST00000045931.10
Zfp410
zinc finger protein 410
chr1_+_74771886 0.095 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.3 1.3 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
1.0 3.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.7 4.0 GO:0003383 apical constriction(GO:0003383)
0.7 4.7 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.6 3.4 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.5 0.9 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.4 2.3 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4 1.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.4 1.4 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.3 2.0 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 3.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.0 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.2 1.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 0.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 2.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 1.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 3.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 1.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 1.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.8 GO:0009404 toxin metabolic process(GO:0009404)
0.2 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.3 GO:0046959 habituation(GO:0046959)
0.1 2.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.5 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 1.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 3.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.6 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.8 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.4 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.8 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.3 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 2.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.4 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 1.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.7 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 1.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.6 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.9 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 2.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 0.5 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.0 1.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 0.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 3.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.4 GO:0032433 filopodium tip(GO:0032433)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 4.6 GO:0043296 apical junction complex(GO:0043296)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 3.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 6.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 2.2 GO:0001726 ruffle(GO:0001726)
0.0 4.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 2.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 6.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 3.1 GO:0005522 profilin binding(GO:0005522)
0.2 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 1.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 1.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 2.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.9 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.5 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.1 1.0 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 3.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 1.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 4.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 3.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 9.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.1 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.9 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.7 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 1.2 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 3.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport