Z-value: 0.764
Transcription factors associated with Tfap4:
Activity-expression correlation:
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Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
5.1
GO:0048663
neuron fate commitment(GO:0048663)
0.0
4.6
GO:0051592
response to calcium ion(GO:0051592)
0.1
3.7
GO:0010866
regulation of triglyceride biosynthetic process(GO:0010866)
0.1
3.3
GO:0032728
positive regulation of interferon-beta production(GO:0032728)
0.4
3.2
GO:0035372
protein localization to microtubule(GO:0035372)
0.6
3.0
GO:0045347
negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.7
2.9
GO:0001920
negative regulation of receptor recycling(GO:0001920)
0.4
2.6
GO:0072513
positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6
2.4
GO:1904451
regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1
2.3
GO:0002495
antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2
1.9
GO:0009404
toxin metabolic process(GO:0009404)
0.1
1.9
GO:0051386
regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0
1.6
GO:0006730
one-carbon metabolic process(GO:0006730)
0.0
1.6
GO:0030518
intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.3
1.5
GO:0070327
thyroid hormone transport(GO:0070327)
0.1
1.5
GO:0060219
camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3
1.4
GO:1903378
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0
1.3
GO:0051642
centrosome localization(GO:0051642)
0.4
1.2
GO:0038095
positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.2
1.2
GO:0048597
post-embryonic camera-type eye morphogenesis(GO:0048597)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
4.4
GO:0005667
transcription factor complex(GO:0005667)
0.3
3.0
GO:0020005
symbiont-containing vacuole membrane(GO:0020005)
0.0
2.7
GO:0005881
cytoplasmic microtubule(GO:0005881)
0.0
2.6
GO:0032993
protein-DNA complex(GO:0032993)
0.0
2.6
GO:0005802
trans-Golgi network(GO:0005802)
0.6
2.4
GO:0097574
lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1
2.3
GO:0032588
trans-Golgi network membrane(GO:0032588)
0.0
1.9
GO:0030667
secretory granule membrane(GO:0030667)
0.0
1.8
GO:0043679
axon terminus(GO:0043679)
0.1
1.5
GO:0042622
photoreceptor outer segment membrane(GO:0042622)
0.3
1.4
GO:1990452
Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0
0.9
GO:0005788
endoplasmic reticulum lumen(GO:0005788)
0.0
0.8
GO:0071564
npBAF complex(GO:0071564)
0.1
0.7
GO:0097512
cardiac myofibril(GO:0097512)
0.1
0.6
GO:0030314
junctional membrane complex(GO:0030314)
0.1
0.6
GO:0097427
microtubule bundle(GO:0097427)
0.0
0.6
GO:0042405
nuclear inclusion body(GO:0042405)
0.0
0.6
GO:0030992
intraciliary transport particle B(GO:0030992)
0.0
0.5
GO:0005891
voltage-gated calcium channel complex(GO:0005891)
0.1
0.4
GO:0016012
sarcoglycan complex(GO:0016012)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
10.5
GO:0042803
protein homodimerization activity(GO:0042803)
0.0
5.1
GO:0046983
protein dimerization activity(GO:0046983)
0.0
4.8
GO:0001078
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.6
3.0
GO:0048248
CXCR3 chemokine receptor binding(GO:0048248)
0.3
2.9
GO:0001025
RNA polymerase III transcription factor binding(GO:0001025)
0.0
2.7
GO:0051219
phosphoprotein binding(GO:0051219)
0.3
2.4
GO:0017034
Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1
2.4
GO:0070016
armadillo repeat domain binding(GO:0070016)
0.0
2.4
GO:0004725
protein tyrosine phosphatase activity(GO:0004725)
0.1
2.3
GO:0042287
MHC protein binding(GO:0042287)
0.0
2.0
GO:0005158
insulin receptor binding(GO:0005158)
0.6
1.9
GO:0016715
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1
1.6
GO:0016151
nickel cation binding(GO:0016151)
0.0
1.6
GO:0005179
hormone activity(GO:0005179)
0.2
1.5
GO:0070324
thyroid hormone binding(GO:0070324)
0.1
1.5
GO:0008484
sulfuric ester hydrolase activity(GO:0008484)
0.0
1.5
GO:0001105
RNA polymerase II transcription coactivator activity(GO:0001105)
0.3
1.4
GO:0050816
phosphothreonine binding(GO:0050816)
0.2
1.3
GO:0001515
opioid peptide activity(GO:0001515)
0.2
1.2
GO:0005021
vascular endothelial growth factor-activated receptor activity(GO:0005021)
Gene overrepresentation in C2:CP category:
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Showing 1 to 9 of 9 entries
Gene overrepresentation in C2:CP:REACTOME category:
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Showing 1 to 16 of 16 entries