Motif ID: Tlx2

Z-value: 1.110


Transcription factors associated with Tlx2:

Gene SymbolEntrez IDGene Name
Tlx2 ENSMUSG00000068327.3 Tlx2



Activity profile for motif Tlx2.

activity profile for motif Tlx2


Sorted Z-values histogram for motif Tlx2

Sorted Z-values for motif Tlx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_82074639 5.171 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr9_-_21037775 4.523 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr15_+_21111452 4.494 ENSMUST00000075132.6
Cdh12
cadherin 12
chr16_+_91225550 4.260 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr8_+_94772009 4.102 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr15_+_54745702 3.876 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr9_+_111311674 3.850 ENSMUST00000078626.3
Trank1
tetratricopeptide repeat and ankyrin repeat containing 1
chr19_+_6401675 3.461 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chrX_-_162565514 3.327 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr6_+_108660772 3.209 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr17_+_68837062 2.984 ENSMUST00000178545.1
Tmem200c
transmembrane protein 200C
chr9_-_107710475 2.937 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_24031006 2.798 ENSMUST00000096164.4
Fam189a2
family with sequence similarity 189, member A2
chr14_+_66344369 2.782 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
Stmn4



stathmin-like 4



chr6_+_108660616 2.780 ENSMUST00000032194.4
Bhlhe40
basic helix-loop-helix family, member e40
chr14_+_66344296 2.779 ENSMUST00000152093.1
ENSMUST00000074523.6
Stmn4

stathmin-like 4

chr11_-_51650813 2.761 ENSMUST00000142721.1
ENSMUST00000156835.1
ENSMUST00000001080.9
N4bp3


NEDD4 binding protein 3


chr9_-_29412204 2.742 ENSMUST00000115237.1
Ntm
neurotrimin
chr13_-_49309217 2.686 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr13_+_13784278 2.613 ENSMUST00000021734.7
Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr14_-_66280949 2.609 ENSMUST00000111121.1
ENSMUST00000022622.7
ENSMUST00000089250.2
Ptk2b


PTK2 protein tyrosine kinase 2 beta


chr6_-_12749193 2.550 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr3_+_8509477 2.533 ENSMUST00000029002.7
Stmn2
stathmin-like 2
chr7_+_87803815 2.525 ENSMUST00000125009.1
ENSMUST00000155358.1
Grm5

glutamate receptor, metabotropic 5

chr1_-_56978534 2.519 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_45925570 2.458 ENSMUST00000027137.4
Slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
chr13_-_68999518 2.412 ENSMUST00000022013.7
Adcy2
adenylate cyclase 2
chr9_+_87015537 2.393 ENSMUST00000058846.4
Ripply2
ripply2 homolog (zebrafish)
chr9_-_112187766 2.337 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_-_193370225 2.333 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr1_-_193370260 2.279 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr5_-_139130159 2.277 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr9_-_112187898 2.205 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_+_34579693 2.189 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chr3_-_113574758 2.177 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr17_+_48932368 2.168 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr16_-_17144415 2.160 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr8_+_46492789 2.124 ENSMUST00000110371.1
Acsl1
acyl-CoA synthetase long-chain family member 1
chr10_+_13966268 2.117 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr8_+_65618009 2.109 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
March1


membrane-associated ring finger (C3HC4) 1


chr10_-_67912620 2.082 ENSMUST00000064656.7
Zfp365
zinc finger protein 365
chr15_+_54571358 2.066 ENSMUST00000025356.2
Mal2
mal, T cell differentiation protein 2
chr12_+_116485714 2.045 ENSMUST00000070733.7
Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr3_-_145649970 2.037 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr13_-_49320219 2.022 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr14_+_74640840 2.020 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr9_-_123678782 2.005 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr6_-_13871477 1.977 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr10_+_78780470 1.968 ENSMUST00000005490.8
Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr3_+_109573907 1.968 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr3_-_96293953 1.968 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr12_+_109540979 1.955 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr1_-_38836090 1.928 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr5_-_67847400 1.904 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr16_-_42340595 1.895 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr13_+_4233730 1.894 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chr3_-_31310349 1.887 ENSMUST00000091259.2
Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr19_+_27217357 1.846 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr3_-_113574242 1.836 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr13_-_54611274 1.826 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr7_-_57387172 1.813 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr4_-_155774563 1.799 ENSMUST00000042196.3
Vwa1
von Willebrand factor A domain containing 1
chr5_-_67847360 1.766 ENSMUST00000072971.6
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr10_+_86779000 1.729 ENSMUST00000099396.2
Nt5dc3
5'-nucleotidase domain containing 3
chr18_-_31317043 1.711 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr14_-_66868572 1.696 ENSMUST00000022629.8
Dpysl2
dihydropyrimidinase-like 2
chrX_-_36989656 1.691 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
Sept6


septin 6


chr16_-_36666067 1.682 ENSMUST00000089620.4
Cd86
CD86 antigen
chr16_-_45408955 1.652 ENSMUST00000163230.1
Cd200
CD200 antigen
chr5_-_67815852 1.649 ENSMUST00000141443.1
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr11_-_52282564 1.647 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr7_-_47132698 1.647 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr13_-_54611332 1.646 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr10_+_79988584 1.606 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr6_+_97210689 1.605 ENSMUST00000044681.6
Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr14_+_66911170 1.603 ENSMUST00000089236.3
ENSMUST00000122431.2
Pnma2

paraneoplastic antigen MA2

chr4_-_149698698 1.597 ENSMUST00000038859.7
ENSMUST00000105690.2
Pik3cd

phosphatidylinositol 3-kinase catalytic delta polypeptide

chr12_+_69241832 1.592 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr15_-_8710734 1.589 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_6658510 1.574 ENSMUST00000045374.7
Ramp3
receptor (calcitonin) activity modifying protein 3
chr4_+_126262325 1.562 ENSMUST00000030660.8
Trappc3
trafficking protein particle complex 3
chr6_-_13871459 1.549 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr3_-_36475688 1.547 ENSMUST00000029266.8
Anxa5
annexin A5
chr4_-_149698552 1.544 ENSMUST00000134534.1
ENSMUST00000146612.1
ENSMUST00000105688.3
Pik3cd


phosphatidylinositol 3-kinase catalytic delta polypeptide


chr3_-_84479418 1.533 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr2_+_107290590 1.531 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr8_-_105637403 1.525 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr11_-_78984831 1.509 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr7_-_90129339 1.498 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr8_-_122551316 1.485 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr13_+_45965211 1.474 ENSMUST00000038032.3
5033430I15Rik
RIKEN cDNA 5033430I15 gene
chr2_+_130405256 1.460 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr3_+_134236483 1.455 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr6_-_99266494 1.421 ENSMUST00000113326.2
Foxp1
forkhead box P1
chr4_-_129558355 1.418 ENSMUST00000167288.1
ENSMUST00000134336.1
Lck

lymphocyte protein tyrosine kinase

chr6_-_92534855 1.417 ENSMUST00000113446.1
Prickle2
prickle homolog 2 (Drosophila)
chr9_-_123678873 1.417 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr11_+_63128973 1.405 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr4_-_129558387 1.356 ENSMUST00000067240.4
Lck
lymphocyte protein tyrosine kinase
chr11_+_43474276 1.351 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr5_-_24842579 1.349 ENSMUST00000030787.8
Rheb
Ras homolog enriched in brain
chr11_-_78984946 1.342 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr3_+_55461758 1.331 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr6_-_56901870 1.323 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr15_-_8710409 1.318 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_64382908 1.316 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr12_+_24651346 1.315 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr16_+_91391721 1.311 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr11_+_102836296 1.309 ENSMUST00000021302.8
ENSMUST00000107072.1
Higd1b

HIG1 domain family, member 1B

chr8_+_104101625 1.299 ENSMUST00000034339.8
Cdh5
cadherin 5
chr3_+_88043098 1.277 ENSMUST00000166021.1
ENSMUST00000029707.7
Gpatch4

G patch domain containing 4

chr2_-_6130117 1.252 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
Proser2


proline and serine rich 2


chr4_-_40239779 1.229 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr19_-_4121536 1.220 ENSMUST00000025767.7
Aip
aryl-hydrocarbon receptor-interacting protein
chr15_+_78935177 1.219 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr16_-_43979050 1.212 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr10_-_62342674 1.199 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chrX_-_144688180 1.194 ENSMUST00000040184.3
Trpc5
transient receptor potential cation channel, subfamily C, member 5
chr13_-_45964964 1.184 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1


chr6_-_72390659 1.177 ENSMUST00000059983.9
Vamp8
vesicle-associated membrane protein 8
chr8_+_70594466 1.175 ENSMUST00000019283.9
Isyna1
myo-inositol 1-phosphate synthase A1
chr1_+_34459746 1.171 ENSMUST00000027302.7
Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr10_+_78574492 1.164 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr8_+_104340594 1.134 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr18_-_61786636 1.122 ENSMUST00000120472.1
Afap1l1
actin filament associated protein 1-like 1
chr4_-_155345696 1.099 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr9_+_94669876 1.092 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr11_+_78188737 1.089 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr14_+_54426902 1.084 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr4_-_129121699 1.077 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr1_+_171437535 1.057 ENSMUST00000043839.4
F11r
F11 receptor
chr8_+_117257019 1.053 ENSMUST00000166750.1
Cmip
c-Maf inducing protein
chr2_-_120154600 1.041 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr13_-_92483996 1.038 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr19_+_26750939 1.022 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_-_102136225 1.020 ENSMUST00000154032.1
Spryd3
SPRY domain containing 3
chr11_-_69921057 1.007 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr2_+_10153563 0.997 ENSMUST00000026886.7
Itih5
inter-alpha (globulin) inhibitor H5
chr9_+_111439063 0.976 ENSMUST00000111879.3
Dclk3
doublecortin-like kinase 3
chr3_+_121723515 0.972 ENSMUST00000029771.8
F3
coagulation factor III
chr11_-_101987004 0.957 ENSMUST00000107173.2
ENSMUST00000107172.1
Dusp3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

chr15_-_93595877 0.957 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr1_-_134332928 0.955 ENSMUST00000168515.1
Ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr11_+_115420059 0.954 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr11_-_69920892 0.952 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr6_-_119330668 0.942 ENSMUST00000112756.1
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr19_-_5924797 0.939 ENSMUST00000055458.4
Cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr9_-_10904766 0.934 ENSMUST00000160216.1
Cntn5
contactin 5
chr7_+_28437447 0.933 ENSMUST00000108292.2
ENSMUST00000108289.1
Gmfg

glia maturation factor, gamma

chr9_-_21927515 0.933 ENSMUST00000178988.1
ENSMUST00000046831.9
Tmem205

transmembrane protein 205

chr10_-_89257578 0.933 ENSMUST00000182341.1
ENSMUST00000182613.1
Ano4

anoctamin 4

chrX_+_72918557 0.923 ENSMUST00000033715.4
Nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr16_-_94526830 0.917 ENSMUST00000023615.6
Dscr3
Down syndrome critical region gene 3
chr11_-_69695802 0.909 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr6_-_31563978 0.906 ENSMUST00000026698.7
Podxl
podocalyxin-like
chr4_-_4138432 0.906 ENSMUST00000070375.7
Penk
preproenkephalin
chr6_-_119330723 0.905 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr10_+_39612934 0.901 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chrX_+_74270812 0.893 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10



chr3_+_159839729 0.884 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr4_-_118490030 0.882 ENSMUST00000047421.5
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_19359477 0.878 ENSMUST00000047036.8
Cd3eap
CD3E antigen, epsilon polypeptide associated protein
chr15_+_78934919 0.873 ENSMUST00000138880.1
ENSMUST00000149580.1
ENSMUST00000041164.3
Nol12


nucleolar protein 12


chr18_+_74065102 0.852 ENSMUST00000066583.1
Gm9925
predicted gene 9925
chr6_-_23839137 0.846 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chrX_+_73503074 0.844 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr10_-_69212996 0.843 ENSMUST00000170048.1
A930033H14Rik
RIKEN cDNA A930033H14 gene
chr4_-_120747248 0.838 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr11_-_21572193 0.833 ENSMUST00000102874.4
Mdh1
malate dehydrogenase 1, NAD (soluble)
chr9_-_10904697 0.831 ENSMUST00000162484.1
Cntn5
contactin 5
chr14_-_41008256 0.821 ENSMUST00000136661.1
Fam213a
family with sequence similarity 213, member A
chr4_+_126609818 0.812 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr11_-_59839745 0.808 ENSMUST00000141415.1
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr2_+_84826997 0.808 ENSMUST00000028470.3
Timm10
translocase of inner mitochondrial membrane 10
chr11_-_59191791 0.807 ENSMUST00000170202.2
Guk1
guanylate kinase 1
chr7_+_46796088 0.807 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chr17_-_45593626 0.799 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr19_-_8723356 0.795 ENSMUST00000170157.1
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chrX_-_43167817 0.793 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr12_-_67221221 0.791 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr19_-_4269140 0.790 ENSMUST00000037992.8
ENSMUST00000113852.4
Ssh3

slingshot homolog 3 (Drosophila)

chr5_-_123141067 0.785 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr15_-_103239812 0.782 ENSMUST00000118152.1
Cbx5
chromobox 5
chr3_-_88503187 0.781 ENSMUST00000120377.1
Lmna
lamin A
chr4_-_40239700 0.775 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_+_156008045 0.769 ENSMUST00000006035.6
Ergic3
ERGIC and golgi 3
chr9_+_21927471 0.764 ENSMUST00000170304.1
ENSMUST00000006403.6
Ccdc159

coiled-coil domain containing 159

chr3_+_151437887 0.756 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr17_-_79355082 0.752 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr2_-_37430835 0.750 ENSMUST00000053098.5
Zbtb6
zinc finger and BTB domain containing 6
chr9_-_71771535 0.742 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
Cgnl1


cingulin-like 1


chr10_+_116301374 0.741 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr8_+_85036906 0.739 ENSMUST00000093360.4
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr2_+_156008088 0.735 ENSMUST00000088650.4
Ergic3
ERGIC and golgi 3
chr17_+_24632671 0.729 ENSMUST00000047611.2
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr1_-_162859684 0.726 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr9_+_104566677 0.719 ENSMUST00000157006.1
Cpne4
copine IV
chr5_+_143933059 0.718 ENSMUST00000166847.1
Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr3_-_110142996 0.714 ENSMUST00000156177.2
Ntng1
netrin G1
chr7_-_142576492 0.709 ENSMUST00000140716.1
H19
H19 fetal liver mRNA

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
1.4 4.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.3 3.9 GO:1990523 bone regeneration(GO:1990523)
1.0 4.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.0 2.9 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.9 2.6 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.8 2.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.8 2.5 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.8 5.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.7 2.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.7 2.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.7 2.0 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.6 1.7 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.5 2.7 GO:0034436 glycoprotein transport(GO:0034436)
0.5 1.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.5 2.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.5 2.0 GO:0009597 detection of virus(GO:0009597)
0.5 1.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.5 2.9 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.5 1.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.5 2.7 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.4 3.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 2.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 1.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.4 1.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 0.8 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4 2.8 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.4 1.2 GO:0090187 zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.4 1.5 GO:0097211 prolactin secretion(GO:0070459) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.4 1.5 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.4 1.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.3 1.7 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.3 3.4 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.3 1.6 GO:2001025 positive regulation of response to drug(GO:2001025)
0.3 2.0 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.3 2.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.3 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 1.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.3 0.9 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.3 0.9 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.3 1.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.3 1.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.3 1.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.7 GO:0001955 blood vessel maturation(GO:0001955)
0.2 0.7 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 2.2 GO:0016198 axon choice point recognition(GO:0016198)
0.2 0.5 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.2 2.1 GO:1903874 ferrous iron transmembrane transport(GO:1903874)
0.2 0.7 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.2 2.2 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.2 6.6 GO:0009648 photoperiodism(GO:0009648)
0.2 2.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.8 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.6 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.2 0.6 GO:0016598 protein arginylation(GO:0016598)
0.2 3.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.2 0.6 GO:0070488 neutrophil aggregation(GO:0070488)
0.2 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 0.6 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.2 0.4 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.2 2.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.5 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.2 2.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 2.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 1.2 GO:0061718 NADH regeneration(GO:0006735) regulation of anion channel activity(GO:0010359) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 0.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 1.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 1.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 1.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.3 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.2 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.1 GO:1900426 positive regulation of defense response to bacterium(GO:1900426)
0.2 1.1 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.2 0.5 GO:0072049 comma-shaped body morphogenesis(GO:0072049)
0.1 1.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:0097298 regulation of nucleus size(GO:0097298)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 2.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 2.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 1.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.7 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 4.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 2.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.3 GO:0015744 succinate transport(GO:0015744)
0.1 1.7 GO:0048266 behavioral response to pain(GO:0048266)
0.1 1.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 2.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 1.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.8 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0002934 desmosome organization(GO:0002934)
0.1 1.4 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.1 1.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 3.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:1990000 amyloid fibril formation(GO:1990000)
0.1 0.6 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.3 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 4.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.1 GO:2000192 negative regulation of fatty acid transport(GO:2000192)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.9 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.2 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.6 GO:0099645 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.8 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 1.0 GO:0006907 pinocytosis(GO:0006907)
0.0 3.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.9 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.7 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.2 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 2.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 1.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.7 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.7 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 2.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.6 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0009303 rRNA transcription(GO:0009303)
0.0 3.7 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.8 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 2.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0007584 response to nutrient(GO:0007584)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.6 GO:0070206 protein trimerization(GO:0070206)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.6 GO:0043627 response to estrogen(GO:0043627)
0.0 0.3 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.0 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005940 septin ring(GO:0005940)
0.4 1.7 GO:0097447 dendritic tree(GO:0097447)
0.4 7.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 3.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3 1.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.3 3.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 0.9 GO:0032280 symmetric synapse(GO:0032280)
0.2 2.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.0 GO:0070852 cell body fiber(GO:0070852)
0.2 1.1 GO:0045179 apical cortex(GO:0045179)
0.2 2.0 GO:0005642 annulate lamellae(GO:0005642)
0.2 2.5 GO:0097449 astrocyte projection(GO:0097449)
0.2 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:1990745 EARP complex(GO:1990745)
0.1 1.6 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.9 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 2.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.8 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 2.0 GO:0005921 gap junction(GO:0005921)
0.1 0.3 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 1.7 GO:0043218 compact myelin(GO:0043218)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.5 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 3.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 2.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.3 GO:0005827 polar microtubule(GO:0005827)
0.1 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 3.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 2.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 3.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 5.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.1 GO:0014704 intercalated disc(GO:0014704)
0.0 3.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.7 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
1.0 6.0 GO:0043426 MRF binding(GO:0043426)
0.7 2.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.7 2.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.6 7.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.6 2.5 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.6 1.8 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.6 2.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 1.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 2.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 2.9 GO:0016936 galactoside binding(GO:0016936)
0.4 3.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.4 1.2 GO:0036004 GAF domain binding(GO:0036004)
0.4 2.0 GO:0019770 IgG receptor activity(GO:0019770)
0.4 3.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 2.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.6 GO:0097643 amylin receptor activity(GO:0097643)
0.3 5.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 2.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 1.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 1.8 GO:0001515 opioid peptide activity(GO:0001515)
0.3 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 6.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 2.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 1.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.2 2.9 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.7 GO:0046870 cadmium ion binding(GO:0046870)
0.2 0.8 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.2 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 0.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.7 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 4.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.5 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.2 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 4.3 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 4.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.5 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.9 GO:0031628 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852)
0.1 2.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.1 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.2 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 3.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 4.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 2.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 5.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 2.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 8.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.8 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 3.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.2 3.7 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 5.4 PID_ARF_3PATHWAY Arf1 pathway
0.2 6.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.8 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 2.0 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 1.6 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 2.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 2.6 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 8.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.9 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 6.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 0.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 5.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.4 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.4 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 1.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.7 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 1.2 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.5 2.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.7 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 2.6 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 2.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 6.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 5.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.1 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 5.0 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 6.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.1 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.1 0.4 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.6 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 3.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.1 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.0 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 5.7 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 0.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.0 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.0 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.6 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.3 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.1 0.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.7 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.6 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.8 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.7 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.8 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.9 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.8 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 3.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE