Motif ID: Ubp1

Z-value: 0.777


Transcription factors associated with Ubp1:

Gene SymbolEntrez IDGene Name
Ubp1 ENSMUSG00000009741.8 Ubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ubp1mm10_v2_chr9_+_113930934_113930987-0.353.1e-02Click!


Activity profile for motif Ubp1.

activity profile for motif Ubp1


Sorted Z-values histogram for motif Ubp1

Sorted Z-values for motif Ubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ubp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_90772435 1.993 ENSMUST00000031320.6
 Pf4
platelet factor 4
chr1_-_75278345 1.962 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr6_-_23248264 1.922 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_-_44799643 1.858 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr7_+_107567445 1.635 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr3_-_82145865 1.626 ENSMUST00000048976.6
 Gucy1a3
guanylate cyclase 1, soluble, alpha 3
chr17_-_50094277 1.590 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr3_+_106113229 1.456 ENSMUST00000079132.5
ENSMUST00000139086.1
 Chia

chitinase, acidic

chr6_-_91807318 1.416 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr16_-_26371828 1.343 ENSMUST00000023154.2
 Cldn1
claudin 1
chr9_+_34486125 1.289 ENSMUST00000115148.2
ENSMUST00000183580.1
 Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr12_+_113152012 1.265 ENSMUST00000006523.7
 Crip1
cysteine-rich protein 1 (intestinal)
chrX_+_73483602 1.250 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr10_-_128549125 1.194 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr4_-_136898803 1.186 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr10_+_79988584 1.174 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr14_-_37098211 1.154 ENSMUST00000022337.9
 Cdhr1
cadherin-related family member 1
chr6_-_91807424 1.149 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chrY_+_897782 1.135 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr5_+_24985840 1.083 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 222 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 2.5 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 2.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.4 2.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.3 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.7 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 1.6 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.1 1.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.4 1.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 1.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 1.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 1.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.1 1.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 1.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 1.1 GO:0032439 endosome localization(GO:0032439)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.3 1.0 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.7 GO:0043198 dendritic shaft(GO:0043198)
0.4 2.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 2.0 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.1 GO:0045179 apical cortex(GO:0045179)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.4 2.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.1 1.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.4 1.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 1.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 0.9 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.3 0.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 2.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.0 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.9 PID_ALK1_PATHWAY ALK1 signaling events
0.1 0.8 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.5 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.4 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.5 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 3.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 3.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 2.8 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.3 2.0 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 1.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.2 1.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.2 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.2 0.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway