Motif ID: Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 1.443


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Uncxmm10_v2_chr5_+_139543889_1395439040.797.3e-09Click!
Shox2mm10_v2_chr3_-_66981279_669813180.511.2e-03Click!
Prrx2mm10_v2_chr2_+_30834972_308349720.134.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_118478182 37.234 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 36.107 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr5_+_139543889 33.333 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr8_-_61902669 20.388 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr3_+_55782500 19.142 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr4_-_97778042 16.310 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_-_62766153 15.846 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_49636847 12.860 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_+_38780284 12.000 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_+_20737306 11.705 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr2_+_25372315 11.558 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr14_-_48665098 10.978 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr8_+_45658666 10.651 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_+_44121167 10.550 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr8_+_45658731 10.279 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr12_+_38780817 9.921 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr3_-_86548268 9.870 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr17_+_34592248 9.869 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr19_+_59458372 9.653 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr14_-_118052235 9.630 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr6_+_8948608 9.628 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chrX_-_60893430 9.447 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_-_72986716 9.254 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr2_-_18048784 9.227 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr12_+_38783503 9.146 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr4_-_110292719 9.129 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_+_25773985 8.915 ENSMUST00000125667.1
Myo10
myosin X
chr7_-_37773555 8.448 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr2_-_168767136 8.432 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr7_-_37772868 8.217 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr3_-_88410295 7.976 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr3_+_125404072 7.702 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr16_-_63864114 7.562 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr6_-_147264124 7.361 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr7_-_115824699 7.302 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr4_+_97777780 7.220 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr11_+_102604370 7.034 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr7_+_114745685 6.867 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr17_-_35697971 6.762 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr3_+_125404292 6.636 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_-_190170671 6.627 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr10_-_45470201 6.612 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr12_+_38783455 6.382 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr16_-_26989974 6.335 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr4_-_45532470 6.257 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr12_+_38781093 6.019 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr6_+_15196949 5.816 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr8_-_84662841 5.693 ENSMUST00000060427.4
Ier2
immediate early response 2
chr7_+_29071597 5.601 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr7_-_73541738 5.546 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr4_-_24430838 5.476 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr1_-_190170178 5.369 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr9_+_96258697 5.317 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr2_-_168767029 5.249 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr1_-_172027269 5.133 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr3_+_76593550 4.950 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chr13_-_78196373 4.905 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr2_-_28916412 4.858 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr1_+_109983737 4.794 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr11_+_60537978 4.694 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr2_+_38341068 4.693 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chrX_+_56454871 4.662 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chrM_+_7005 4.649 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr3_-_17786834 4.555 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr15_+_55307743 4.452 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr3_+_159839729 4.314 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr10_+_73821857 4.139 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chrX_+_9885622 4.069 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr2_+_61804453 4.018 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr14_+_79515618 3.958 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr10_+_26772477 3.910 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr8_+_45627709 3.813 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr13_-_97747373 3.704 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_-_37769624 3.656 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr9_+_119063429 3.512 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr13_-_97747399 3.443 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_116067391 3.411 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_172027251 3.351 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr8_-_26119125 3.314 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr13_+_23575753 3.180 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr4_+_8690399 3.176 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr3_+_134236483 3.135 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr6_+_7555053 3.132 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chrM_+_2743 3.108 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr5_+_138187485 3.093 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr1_-_163725123 3.011 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr2_-_28916668 2.967 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr4_-_155056784 2.966 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr9_+_65890237 2.955 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr16_-_45724600 2.880 ENSMUST00000096057.4
Tagln3
transgelin 3
chr1_+_110099295 2.865 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr2_+_181767283 2.700 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr2_+_181767040 2.687 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr18_-_54990124 2.684 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr6_+_134929118 2.676 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr2_-_79456750 2.669 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr1_+_132298606 2.658 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr14_+_73237891 2.591 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr4_-_35845204 2.425 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr8_-_31918203 2.391 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr17_+_45734506 2.231 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr11_-_50292302 2.076 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr5_+_115235836 2.046 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chrM_+_9870 2.021 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_52038005 2.005 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chrM_+_10167 1.943 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr1_+_153665274 1.936 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr5_+_34999046 1.929 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr10_+_88091070 1.907 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr11_+_94327984 1.850 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr1_-_14310198 1.841 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr1_+_82233112 1.806 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr5_-_138187177 1.784 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr3_+_5218546 1.774 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr18_+_61639542 1.764 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr18_+_57468478 1.752 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr3_-_79841729 1.738 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr11_-_3931960 1.733 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr8_-_120228221 1.717 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr6_-_57535422 1.703 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr1_-_78968079 1.699 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr1_+_153665666 1.696 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr6_-_148946146 1.675 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr8_-_45382198 1.669 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr9_-_96437434 1.636 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr4_+_62583568 1.612 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr6_+_34709442 1.587 ENSMUST00000115021.1
Cald1
caldesmon 1
chr10_+_37139558 1.575 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr17_+_73107982 1.561 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1


lysocardiolipin acyltransferase 1


chr2_+_116067213 1.522 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chrX_-_102157065 1.509 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr16_+_33684538 1.505 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr7_-_5014645 1.469 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr11_-_3931789 1.463 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr3_-_157925056 1.456 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr3_+_5218516 1.434 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr4_-_132510493 1.432 ENSMUST00000030724.8
Sesn2
sestrin 2
chr18_-_75697639 1.407 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr5_+_34999070 1.389 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr9_+_89199319 1.341 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr4_-_42168603 1.339 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr3_+_32436376 1.330 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_+_153665587 1.322 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_104768510 1.316 ENSMUST00000062528.8
Cdh20
cadherin 20
chr1_+_153665627 1.287 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr14_-_48667508 1.270 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr1_-_24612700 1.263 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr13_-_53473074 1.261 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr10_-_80421847 1.246 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_46667375 1.236 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr9_+_45138437 1.229 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr2_+_23069210 1.223 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr13_-_114458720 1.188 ENSMUST00000022287.5
Fst
follistatin
chr3_+_76075583 1.184 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr7_+_123123870 1.183 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr15_-_34495180 1.163 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chrX_-_74246534 1.158 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr3_+_95164306 1.157 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr14_+_53324632 1.156 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr18_+_4993795 1.149 ENSMUST00000153016.1
Svil
supervillin
chr12_+_55598917 1.141 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr3_-_66296807 1.137 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr7_+_49910112 1.129 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr9_+_72806874 1.094 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr14_-_76010863 1.093 ENSMUST00000088922.4
Gtf2f2
general transcription factor IIF, polypeptide 2
chr15_-_9140374 1.089 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr17_-_48432723 1.084 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr16_+_43503607 1.078 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr14_+_54259227 1.071 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr13_+_23555023 1.015 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr7_+_125829653 1.003 ENSMUST00000124223.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr8_-_41016749 0.995 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr5_+_135106881 0.988 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr1_-_13372434 0.980 ENSMUST00000081713.4
Ncoa2
nuclear receptor coactivator 2
chr1_+_10993452 0.968 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr3_+_5218589 0.968 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr12_-_57546121 0.953 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr2_+_125068118 0.948 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr7_+_64501687 0.947 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_-_37359274 0.946 ENSMUST00000009174.8
Pdcl
phosducin-like
chrX_+_159303266 0.930 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr3_-_154328634 0.927 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr2_-_170194033 0.926 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr2_+_83724397 0.926 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr7_+_64502090 0.925 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr11_+_98798653 0.924 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr18_-_56975333 0.920 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr10_+_127420867 0.880 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr12_+_52516077 0.877 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr3_+_32515295 0.872 ENSMUST00000029203.7
Zfp639
zinc finger protein 639
chr9_+_35423582 0.869 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr5_+_34999111 0.854 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr1_+_156035392 0.847 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr19_+_24875679 0.817 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr7_+_28881656 0.790 ENSMUST00000066880.4
Capn12
calpain 12
chr2_+_174327747 0.781 ENSMUST00000087871.4
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chrX_+_140956892 0.778 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr1_-_12991109 0.769 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr12_+_3954943 0.767 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr11_+_114851507 0.760 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
24.4 73.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
4.2 33.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
4.0 12.0 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
4.0 43.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
3.1 12.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.8 8.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
2.5 7.6 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.6 9.6 GO:0006570 tyrosine metabolic process(GO:0006570)
1.4 4.3 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
1.4 7.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.3 3.9 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.3 20.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.3 1.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.2 4.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
1.1 7.6 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.1 20.4 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
1.1 3.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.0 12.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.0 12.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.0 1.9 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
0.8 4.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.8 7.4 GO:0043129 surfactant homeostasis(GO:0043129)
0.8 4.0 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.8 3.2 GO:0015889 cobalamin transport(GO:0015889)
0.8 13.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.7 6.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.7 2.1 GO:0003162 atrioventricular node development(GO:0003162)
0.7 9.4 GO:0060013 righting reflex(GO:0060013)
0.7 2.7 GO:0060729 pancreatic A cell differentiation(GO:0003310) intestinal epithelial structure maintenance(GO:0060729)
0.6 1.9 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.6 1.8 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.6 7.2 GO:0072189 ureter development(GO:0072189)
0.6 27.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.6 6.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 4.7 GO:0021978 telencephalon regionalization(GO:0021978)
0.5 4.6 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.5 1.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.5 5.4 GO:0060539 diaphragm development(GO:0060539)
0.5 1.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 1.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 1.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 0.9 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.5 9.4 GO:0007530 sex determination(GO:0007530)
0.4 6.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159)
0.4 3.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 9.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.4 1.1 GO:0036233 glycine import(GO:0036233)
0.4 3.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.4 1.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 1.0 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.3 0.9 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.3 0.9 GO:0050748 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044) negative regulation of lipoprotein metabolic process(GO:0050748)
0.3 6.9 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.3 2.0 GO:0009249 protein lipoylation(GO:0009249)
0.2 4.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 4.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 1.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 0.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.2 1.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 0.6 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.2 1.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 0.3 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2 1.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 0.8 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.8 GO:0051697 protein delipidation(GO:0051697)
0.2 1.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 8.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 5.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 3.5 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.7 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 3.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 4.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 2.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 3.6 GO:0030901 midbrain development(GO:0030901)
0.1 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.4 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 9.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 3.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 1.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.1 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 9.9 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.1 3.5 GO:0051693 actin filament capping(GO:0051693)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.1 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.1 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.9 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.3 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation by host of viral process(GO:0044793) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 8.9 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0071455 regulation of integrin biosynthetic process(GO:0045113) cellular response to hyperoxia(GO:0071455)
0.0 1.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.6 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 2.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.9 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 3.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 4.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.2 GO:0061013 regulation of mRNA catabolic process(GO:0061013) positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.6 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 4.5 GO:0007059 chromosome segregation(GO:0007059)
0.0 8.0 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0060187 cell pole(GO:0060187)
1.3 8.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.6 1.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.6 9.1 GO:0042788 polysomal ribosome(GO:0042788)
0.5 3.3 GO:0070695 FHF complex(GO:0070695)
0.5 20.4 GO:0002102 podosome(GO:0002102)
0.5 2.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 2.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 9.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 0.9 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.3 1.4 GO:0031523 Myb complex(GO:0031523)
0.3 3.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.6 GO:0030478 actin cap(GO:0030478)
0.2 0.9 GO:0072487 MSL complex(GO:0072487)
0.2 6.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 1.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 8.9 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0044301 climbing fiber(GO:0044301)
0.1 4.3 GO:0032590 dendrite membrane(GO:0032590)
0.1 4.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 5.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 4.2 GO:0097440 apical dendrite(GO:0097440)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 4.5 GO:0032420 stereocilium(GO:0032420)
0.1 2.3 GO:0070469 respiratory chain(GO:0070469)
0.1 13.7 GO:0000792 heterochromatin(GO:0000792)
0.1 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 6.2 GO:0070382 exocytic vesicle(GO:0070382)
0.1 1.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.0 GO:0000776 kinetochore(GO:0000776)
0.1 8.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 17.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.4 GO:0051286 cell tip(GO:0051286)
0.1 5.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.2 GO:0000178 cytoplasmic exosome (RNase complex)(GO:0000177) exosome (RNase complex)(GO:0000178)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 258.6 GO:0005634 nucleus(GO:0005634)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 6.5 GO:0005925 focal adhesion(GO:0005925)
0.0 6.1 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 4.0 GO:0005938 cell cortex(GO:0005938)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 14.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.7 25.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.5 12.0 GO:0050693 LBD domain binding(GO:0050693)
1.2 4.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
1.2 76.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.9 2.8 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.9 6.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.8 6.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 9.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.7 7.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.7 8.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.7 6.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.6 1.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 5.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.5 3.2 GO:0031419 cobalamin binding(GO:0031419)
0.4 3.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 1.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.3 10.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 6.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 14.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 0.9 GO:0005118 sevenless binding(GO:0005118)
0.3 8.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 2.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 9.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 1.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 9.1 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 1.4 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 78.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 0.9 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.2 1.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.2 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2 3.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 19.1 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.1 109.4 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 3.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.4 GO:1904047 nitrite reductase activity(GO:0098809) S-adenosyl-L-methionine binding(GO:1904047)
0.1 6.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.2 GO:0048185 activin binding(GO:0048185)
0.1 6.1 GO:0030507 spectrin binding(GO:0030507)
0.1 4.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.1 1.3 GO:0005542 folic acid binding(GO:0005542)
0.1 2.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.0 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 3.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0005168 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 13.3 GO:0003779 actin binding(GO:0003779)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 13.4 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 44.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
1.3 73.3 PID_IL12_2PATHWAY IL12-mediated signaling events
0.3 14.5 PID_ARF6_PATHWAY Arf6 signaling events
0.3 10.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 6.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.3 9.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.3 11.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.3 7.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 2.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 4.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 6.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 13.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 4.9 NABA_COLLAGENS Genes encoding collagen proteins
0.1 2.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 0.9 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.1 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 2.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.3 ST_ADRENERGIC Adrenergic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 2.6 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 2.9 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.2 14.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 0.8 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 8.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.1 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 18.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.1 0.9 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 9.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 4.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 4.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.3 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 3.4 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 1.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes