Motif ID: Zbtb33_Chd2

Z-value: 2.498

Transcription factors associated with Zbtb33_Chd2:

Gene SymbolEntrez IDGene Name
Chd2 ENSMUSG00000078671.4 Chd2
Zbtb33 ENSMUSG00000048047.3 Zbtb33

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb33mm10_v2_chrX_+_38189780_381898260.841.1e-10Click!
Chd2mm10_v2_chr7_-_73541738_735417580.794.9e-09Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb33_Chd2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_34833631 16.751 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr11_-_90638062 15.550 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr5_+_45669907 13.697 ENSMUST00000117396.1
Ncapg
non-SMC condensin I complex, subunit G
chr4_-_118437331 9.916 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr3_+_69004969 9.873 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr3_+_69004711 9.706 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr9_-_72491939 9.637 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr16_+_48994185 9.440 ENSMUST00000117994.1
ENSMUST00000048374.5
C330027C09Rik

RIKEN cDNA C330027C09 gene

chr19_+_38931008 9.237 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr9_+_121719172 8.953 ENSMUST00000035112.6
ENSMUST00000182311.1
Nktr

natural killer tumor recognition sequence

chr15_+_99074968 8.713 ENSMUST00000039665.6
Troap
trophinin associated protein
chr11_+_29172890 8.603 ENSMUST00000102856.2
ENSMUST00000020755.5
Smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

chr9_+_54863742 8.126 ENSMUST00000034843.7
Ireb2
iron responsive element binding protein 2
chr19_+_38930909 8.087 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr4_+_24496434 8.049 ENSMUST00000108222.2
ENSMUST00000138567.2
ENSMUST00000050446.6
Mms22l


MMS22-like, DNA repair protein


chr9_+_121719403 7.974 ENSMUST00000182225.1
Nktr
natural killer tumor recognition sequence
chr11_+_98203059 7.898 ENSMUST00000107539.1
Cdk12
cyclin-dependent kinase 12
chr2_-_156180135 7.306 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr14_-_57826128 7.097 ENSMUST00000022536.2
Ska3
spindle and kinetochore associated complex subunit 3
chr17_+_45433823 6.926 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr14_-_105176860 6.864 ENSMUST00000163545.1
Rbm26
RNA binding motif protein 26
chr4_+_94614483 6.783 ENSMUST00000030311.4
ENSMUST00000107104.2
Ift74

intraflagellar transport 74

chr1_+_130717320 6.454 ENSMUST00000049813.4
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr8_-_80739497 6.377 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr3_+_152396664 6.348 ENSMUST00000089982.4
ENSMUST00000106101.1
Zzz3

zinc finger, ZZ domain containing 3

chr12_+_9029982 6.279 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr12_+_116405397 6.114 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr14_-_105177280 6.103 ENSMUST00000100327.3
ENSMUST00000022715.7
Rbm26

RNA binding motif protein 26

chr6_+_146577859 5.907 ENSMUST00000067404.6
ENSMUST00000111663.2
ENSMUST00000058245.4
Fgfr1op2


FGFR1 oncogene partner 2


chr14_-_105177263 5.851 ENSMUST00000163499.1
Rbm26
RNA binding motif protein 26
chr14_-_104467984 5.622 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr17_-_42876417 4.763 ENSMUST00000024709.7
Cd2ap
CD2-associated protein
chrX_-_166440671 4.529 ENSMUST00000049501.8
Ofd1
oral-facial-digital syndrome 1 gene homolog (human)
chr5_+_30666886 4.484 ENSMUST00000144742.1
Cenpa
centromere protein A
chr5_+_53590453 4.482 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_127633134 4.397 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr11_-_77607812 4.379 ENSMUST00000058496.7
Taok1
TAO kinase 1
chr5_+_33658567 4.351 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr11_-_73138245 4.251 ENSMUST00000052140.2
Gsg2
germ cell-specific gene 2
chr6_-_146577825 4.196 ENSMUST00000032427.8
Asun
asunder, spermatogenesis regulator
chr5_+_53590215 4.180 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr6_+_120666388 4.169 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr10_-_88146867 3.963 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr3_-_69004565 3.792 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr3_-_69004503 3.685 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr2_-_37422869 3.684 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr7_-_131410495 3.679 ENSMUST00000121033.1
ENSMUST00000046306.8
Ikzf5

IKAROS family zinc finger 5

chr3_-_69004475 3.636 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr1_-_24100306 3.595 ENSMUST00000027337.8
Fam135a
family with sequence similarity 135, member A
chr7_-_131410325 3.572 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr6_+_38551334 3.565 ENSMUST00000163047.1
ENSMUST00000161538.1
ENSMUST00000057692.4
Luc7l2


LUC7-like 2 (S. cerevisiae)


chr1_-_119836999 3.532 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr12_-_98901478 3.490 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr17_+_56040350 3.444 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr7_+_55794146 3.431 ENSMUST00000032627.3
Tubgcp5
tubulin, gamma complex associated protein 5
chr5_-_53707532 3.423 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr10_+_42761483 3.418 ENSMUST00000019937.4
Sec63
SEC63-like (S. cerevisiae)
chr7_+_133637686 3.383 ENSMUST00000128901.2
2700050L05Rik
RIKEN cDNA 2700050L05 gene
chr7_+_133637543 3.218 ENSMUST00000051169.6
2700050L05Rik
RIKEN cDNA 2700050L05 gene
chr8_+_53511695 3.217 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr3_+_30792876 3.107 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr2_+_60209887 3.045 ENSMUST00000102748.4
ENSMUST00000102747.1
March7

membrane-associated ring finger (C3HC4) 7

chr2_+_121867083 3.043 ENSMUST00000089912.5
ENSMUST00000089915.3
Casc4

cancer susceptibility candidate 4

chr2_-_125123618 3.004 ENSMUST00000142718.1
ENSMUST00000152367.1
ENSMUST00000067780.3
ENSMUST00000147105.1
Myef2



myelin basic protein expression factor 2, repressor



chr6_+_83326071 3.003 ENSMUST00000038658.8
ENSMUST00000101245.2
Mob1a

MOB kinase activator 1A

chr5_+_33658123 2.999 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr14_-_78536854 2.998 ENSMUST00000022593.5
Akap11
A kinase (PRKA) anchor protein 11
chr1_-_119837338 2.997 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr6_+_83142387 2.978 ENSMUST00000130622.1
ENSMUST00000129316.1
Rtkn

rhotekin

chr6_+_133105239 2.957 ENSMUST00000100864.4
2700089E24Rik
RIKEN cDNA 2700089E24 gene
chr1_-_155972887 2.946 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr12_+_112678803 2.898 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
Zbtb42


zinc finger and BTB domain containing 42


chr6_+_83326016 2.889 ENSMUST00000055261.4
Mob1a
MOB kinase activator 1A
chr10_+_11149406 2.858 ENSMUST00000044053.6
Shprh
SNF2 histone linker PHD RING helicase
chr14_-_78536762 2.856 ENSMUST00000123853.1
Akap11
A kinase (PRKA) anchor protein 11
chr8_-_94838255 2.855 ENSMUST00000161762.1
ENSMUST00000162538.1
Ciapin1

cytokine induced apoptosis inhibitor 1

chr2_+_121866918 2.842 ENSMUST00000078752.3
ENSMUST00000110586.3
Casc4

cancer susceptibility candidate 4

chr1_-_80340311 2.811 ENSMUST00000164108.1
Cul3
cullin 3
chr6_+_38551786 2.796 ENSMUST00000161227.1
Luc7l2
LUC7-like 2 (S. cerevisiae)
chr1_-_119837613 2.794 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chrX_-_37110257 2.791 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr5_+_88720855 2.788 ENSMUST00000113229.1
ENSMUST00000006424.7
Mob1b

MOB kinase activator 1B

chr10_-_63023847 2.749 ENSMUST00000119814.2
Hnrnph3
heterogeneous nuclear ribonucleoprotein H3
chr10_+_11149449 2.742 ENSMUST00000054814.7
ENSMUST00000159541.1
Shprh

SNF2 histone linker PHD RING helicase

chr2_-_119477613 2.737 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr9_+_92542223 2.718 ENSMUST00000070522.7
ENSMUST00000160359.1
Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chr7_-_34389540 2.647 ENSMUST00000085585.5
Lsm14a
LSM14 homolog A (SCD6, S. cerevisiae)
chrX_+_151803642 2.611 ENSMUST00000156616.2
Huwe1
HECT, UBA and WWE domain containing 1
chr9_-_53667429 2.610 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr17_+_28691342 2.578 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14



chr11_-_106272927 2.574 ENSMUST00000021052.9
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr9_-_64172879 2.573 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr5_+_33658550 2.512 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr9_+_25252439 2.451 ENSMUST00000115272.2
ENSMUST00000165594.2
Sept7

septin 7

chr3_-_122984404 2.436 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr5_-_124425572 2.378 ENSMUST00000168651.1
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr8_-_40308331 2.340 ENSMUST00000118639.1
Fgf20
fibroblast growth factor 20
chr3_+_152210458 2.333 ENSMUST00000166984.1
ENSMUST00000106121.1
Fubp1

far upstream element (FUSE) binding protein 1

chrX_+_23693043 2.330 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chr7_-_48881032 2.319 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chrX_+_13071500 2.311 ENSMUST00000089302.4
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr4_+_133574728 2.308 ENSMUST00000030662.2
Gpatch3
G patch domain containing 3
chr7_+_131410601 2.244 ENSMUST00000015829.7
ENSMUST00000117518.1
Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr5_+_110286306 2.242 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr3_-_113630068 2.191 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr5_-_124425907 2.148 ENSMUST00000065263.5
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr10_-_63023881 2.133 ENSMUST00000118898.1
ENSMUST00000020263.7
Hnrnph3

heterogeneous nuclear ribonucleoprotein H3

chr2_+_109890846 2.126 ENSMUST00000028583.7
Lin7c
lin-7 homolog C (C. elegans)
chr18_+_49832622 2.124 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr1_-_106796687 2.103 ENSMUST00000094646.5
Vps4b
vacuolar protein sorting 4b (yeast)
chr13_-_111490111 2.092 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr1_-_80340480 2.073 ENSMUST00000163119.1
Cul3
cullin 3
chr3_+_33800158 2.042 ENSMUST00000139880.1
ENSMUST00000076916.6
ENSMUST00000142280.1
ENSMUST00000117915.1
ENSMUST00000108210.2
Ttc14




tetratricopeptide repeat domain 14




chr18_+_57878620 2.039 ENSMUST00000115366.2
Slc12a2
solute carrier family 12, member 2
chr13_-_111490028 2.032 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr3_-_88410295 1.966 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr16_-_48994081 1.958 ENSMUST00000121869.1
Dzip3
DAZ interacting protein 3, zinc finger
chr4_-_41464816 1.948 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr5_-_140321524 1.934 ENSMUST00000031534.6
Mad1l1
MAD1 mitotic arrest deficient 1-like 1
chrX_+_13280970 1.931 ENSMUST00000000804.6
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr9_-_55512156 1.916 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr17_+_14943184 1.915 ENSMUST00000052691.8
ENSMUST00000164837.2
ENSMUST00000174004.1
1600012H06Rik


RIKEN cDNA 1600012H06 gene


chr10_+_83543941 1.886 ENSMUST00000038388.5
A230046K03Rik
RIKEN cDNA A230046K03 gene
chr2_+_10080600 1.877 ENSMUST00000042512.7
Kin
antigenic determinant of rec-A protein
chr19_-_12796108 1.861 ENSMUST00000038627.8
Zfp91
zinc finger protein 91
chr13_-_54565368 1.858 ENSMUST00000026989.8
4833439L19Rik
RIKEN cDNA 4833439L19 gene
chr3_-_69044697 1.850 ENSMUST00000136512.1
ENSMUST00000143454.1
ENSMUST00000107802.1
Trim59


tripartite motif-containing 59


chr1_+_74391479 1.825 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr2_-_168207063 1.824 ENSMUST00000088001.5
Adnp
activity-dependent neuroprotective protein
chrX_+_13071470 1.817 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr13_-_54565299 1.799 ENSMUST00000153065.1
ENSMUST00000126295.1
ENSMUST00000143144.1
ENSMUST00000132136.1
4833439L19Rik



RIKEN cDNA 4833439L19 gene



chr6_-_134566913 1.772 ENSMUST00000032322.8
Lrp6
low density lipoprotein receptor-related protein 6
chr2_-_69789568 1.767 ENSMUST00000094942.3
Ccdc173
coiled-coil domain containing 173
chr2_+_69897220 1.748 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr8_+_107293500 1.746 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
Nfat5


nuclear factor of activated T cells 5


chr15_+_6708372 1.739 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr5_-_36988922 1.733 ENSMUST00000166339.1
ENSMUST00000043964.6
Wfs1

Wolfram syndrome 1 homolog (human)

chr7_+_128744870 1.729 ENSMUST00000042942.8
Sec23ip
Sec23 interacting protein
chr3_-_30793549 1.726 ENSMUST00000180833.1
4933429H19Rik
RIKEN cDNA 4933429H19 gene
chr11_-_84870812 1.725 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chrX_+_109095359 1.724 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr13_-_3611064 1.719 ENSMUST00000096069.3
BC016423
cDNA sequence BC016423
chr3_+_107036156 1.710 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr14_+_99099433 1.669 ENSMUST00000022650.7
Pibf1
progesterone immunomodulatory binding factor 1
chr1_-_179803625 1.648 ENSMUST00000027768.7
Ahctf1
AT hook containing transcription factor 1
chr2_-_144270852 1.642 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr11_-_69395333 1.614 ENSMUST00000108660.1
ENSMUST00000051620.4
Cyb5d1

cytochrome b5 domain containing 1

chr3_+_40846970 1.593 ENSMUST00000108078.2
3110057O12Rik
RIKEN cDNA 3110057O12 gene
chr9_+_3004457 1.581 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr2_+_69897255 1.576 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr4_-_94979063 1.560 ENSMUST00000075872.3
Mysm1
myb-like, SWIRM and MPN domains 1
chr9_+_3015654 1.543 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr11_-_60210410 1.502 ENSMUST00000144942.1
Srebf1
sterol regulatory element binding transcription factor 1
chr3_+_107631322 1.486 ENSMUST00000106703.1
Gm10961
predicted gene 10961
chr3_-_144720315 1.481 ENSMUST00000163279.1
Sh3glb1
SH3-domain GRB2-like B1 (endophilin)
chr9_+_108517070 1.475 ENSMUST00000006851.8
ENSMUST00000112155.3
Qrich1

glutamine-rich 1

chr5_+_52834009 1.466 ENSMUST00000031072.7
Anapc4
anaphase promoting complex subunit 4
chr6_+_138140521 1.440 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr4_+_131873608 1.439 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr8_+_94838321 1.432 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)

chr9_+_3017408 1.431 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chrX_+_42151002 1.431 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr11_+_96789213 1.419 ENSMUST00000079702.3
Cbx1
chromobox 1
chr5_-_33657889 1.389 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr8_-_9977650 1.383 ENSMUST00000170033.1
Lig4
ligase IV, DNA, ATP-dependent
chr4_-_9669068 1.377 ENSMUST00000078139.6
ENSMUST00000108340.2
ENSMUST00000084915.4
ENSMUST00000108337.1
ENSMUST00000084912.5
ENSMUST00000038564.6
ENSMUST00000146441.1
ENSMUST00000098275.2
Asph







aspartate-beta-hydroxylase







chr11_+_96789149 1.371 ENSMUST00000093943.3
Cbx1
chromobox 1
chr8_+_46163651 1.369 ENSMUST00000034048.6
ENSMUST00000145229.1
4933411K20Rik

RIKEN cDNA 4933411K20 gene

chr16_-_48993931 1.364 ENSMUST00000114516.1
Dzip3
DAZ interacting protein 3, zinc finger
chr6_+_18848571 1.335 ENSMUST00000056398.8
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr11_-_84870712 1.330 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr7_+_90442729 1.328 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr1_-_106796609 1.324 ENSMUST00000112736.1
Vps4b
vacuolar protein sorting 4b (yeast)
chr6_-_148211996 1.322 ENSMUST00000126698.1
Ergic2
ERGIC and golgi 2
chr2_+_22622183 1.320 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr7_+_13278778 1.316 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr13_-_43480973 1.303 ENSMUST00000144326.2
Ranbp9
RAN binding protein 9
chr8_+_46163733 1.296 ENSMUST00000110376.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr11_+_96789118 1.294 ENSMUST00000018810.3
Cbx1
chromobox 1
chr14_+_34673948 1.288 ENSMUST00000090027.3
Wapal
wings apart-like homolog (Drosophila)
chr2_-_144270504 1.287 ENSMUST00000028909.4
Snx5
sorting nexin 5
chr10_+_20312461 1.282 ENSMUST00000092678.3
ENSMUST00000043881.5
Bclaf1

BCL2-associated transcription factor 1

chr3_+_106684943 1.268 ENSMUST00000098751.3
Lrif1
ligand dependent nuclear receptor interacting factor 1
chr14_-_59440779 1.268 ENSMUST00000111253.2
ENSMUST00000095775.3
ENSMUST00000161459.1
Setdb2


SET domain, bifurcated 2


chr1_-_138856819 1.259 ENSMUST00000112025.1
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr13_+_63815240 1.256 ENSMUST00000021926.5
ENSMUST00000095724.3
ENSMUST00000143449.1
ENSMUST00000067821.5
Ercc6l2



excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2



chr18_+_24205303 1.253 ENSMUST00000000430.7
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chrX_+_37126777 1.244 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr10_-_7956223 1.237 ENSMUST00000146444.1
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr3_+_135438722 1.233 ENSMUST00000166033.1
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr7_-_144582392 1.201 ENSMUST00000033394.7
Fadd
Fas (TNFRSF6)-associated via death domain
chr6_+_30738044 1.194 ENSMUST00000128398.1
ENSMUST00000163949.2
ENSMUST00000124665.1
Mest


mesoderm specific transcript


chr14_+_16365171 1.193 ENSMUST00000017629.4
Top2b
topoisomerase (DNA) II beta
chr9_+_64281575 1.176 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr11_-_84870646 1.169 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr6_-_108185552 1.168 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr10_+_75037066 1.156 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr4_+_62525369 1.149 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr4_+_21727695 1.149 ENSMUST00000065928.4
Ccnc
cyclin C
chr1_+_160195215 1.147 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
2.9 8.7 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
2.7 8.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
2.5 17.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
2.4 19.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.2 6.5 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
1.5 4.5 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.5 16.3 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
1.4 4.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.3 1.3 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
1.2 20.9 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
1.2 10.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.2 12.9 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.2 6.9 GO:0016584 nucleosome positioning(GO:0016584)
1.1 3.4 GO:1903722 regulation of centriole elongation(GO:1903722)
1.1 3.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.1 3.4 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
1.1 5.6 GO:0019230 proprioception(GO:0019230)
1.0 6.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.0 4.8 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.8 4.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.8 3.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.8 2.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.7 2.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.7 2.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.7 2.0 GO:0030321 transepithelial chloride transport(GO:0030321) transepithelial ammonium transport(GO:0070634)
0.7 2.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.6 1.9 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.6 10.4 GO:0030953 astral microtubule organization(GO:0030953)
0.6 16.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.6 1.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.6 1.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.5 1.6 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.5 6.1 GO:0030261 chromosome condensation(GO:0030261)
0.5 9.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.5 4.2 GO:0001842 neural fold formation(GO:0001842)
0.5 1.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 2.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.4 3.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.4 3.0 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4 2.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 1.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.4 1.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.4 3.7 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.4 1.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 2.6 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.4 1.4 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 1.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 2.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.3 10.1 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.3 1.7 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.3 1.9 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 1.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 4.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 0.9 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.3 0.9 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.3 2.6 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.3 1.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.3 1.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 0.8 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 3.0 GO:0002643 regulation of tolerance induction(GO:0002643)
0.3 1.0 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 2.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 3.2 GO:0006517 protein deglycosylation(GO:0006517)
0.2 1.3 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.2 2.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.8 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 15.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 8.7 GO:0035329 hippo signaling(GO:0035329)
0.2 1.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 0.8 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 1.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.2 1.5 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.2 0.7 GO:0060744 thelarche(GO:0042695) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) mammary gland branching involved in thelarche(GO:0060744) mammary gland branching involved in pregnancy(GO:0060745) positive regulation of G0 to G1 transition(GO:0070318)
0.2 1.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 4.0 GO:0019430 removal of superoxide radicals(GO:0019430)
0.2 1.7 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.2 1.5 GO:0006560 proline metabolic process(GO:0006560)
0.2 2.5 GO:0031268 pseudopodium organization(GO:0031268)
0.2 0.5 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 2.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 1.0 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.5 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 0.8 GO:0033762 response to glucagon(GO:0033762)
0.2 0.9 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.4 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 3.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.7 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.8 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 2.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.7 GO:0001675 acrosome assembly(GO:0001675)
0.1 1.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 4.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.9 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.1 1.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 4.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 9.1 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.1 4.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 2.1 GO:0030033 microvillus assembly(GO:0030033)
0.1 2.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 1.1 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 0.8 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.1 1.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 7.1 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 2.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.7 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.4 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1 1.4 GO:0006907 pinocytosis(GO:0006907)
0.1 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.4 GO:0006284 base-excision repair(GO:0006284)
0.1 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 6.7 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.3 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 2.3 GO:0060043 regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.4 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.8 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 1.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.7 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 2.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 5.0 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 7.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 3.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.5 GO:0006415 translational termination(GO:0006415)
0.0 1.2 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.3 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) thermoception(GO:0050955)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.0 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.0 0.7 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.0 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 2.6 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 1.5 GO:0006310 DNA recombination(GO:0006310)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.7 GO:0001935 endothelial cell proliferation(GO:0001935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 39.4 GO:0000796 condensin complex(GO:0000796)
2.7 8.0 GO:0035101 FACT complex(GO:0035101)
2.6 7.9 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
1.8 23.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.7 8.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.1 3.4 GO:0033186 CAF-1 complex(GO:0033186)
1.1 4.5 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
1.0 4.2 GO:0090537 CERF complex(GO:0090537)
0.9 3.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.9 2.6 GO:1990423 RZZ complex(GO:1990423)
0.8 2.5 GO:0005940 septin ring(GO:0005940)
0.7 4.9 GO:0005827 polar microtubule(GO:0005827)
0.7 19.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.6 6.4 GO:0016589 NURF complex(GO:0016589)
0.6 1.8 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.5 1.6 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.5 2.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5 1.5 GO:0031417 NatC complex(GO:0031417)
0.5 2.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 1.9 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.5 11.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.5 2.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 12.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 2.9 GO:0097422 tubular endosome(GO:0097422)
0.4 3.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 6.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.4 2.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 3.4 GO:0090543 Flemming body(GO:0090543)
0.3 2.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.6 GO:0030870 Mre11 complex(GO:0030870)
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.2 1.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 0.9 GO:0071942 XPC complex(GO:0071942)
0.2 5.5 GO:0005685 U1 snRNP(GO:0005685)
0.2 1.7 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.2 0.6 GO:0031251 PAN complex(GO:0031251)
0.2 5.9 GO:0034451 centriolar satellite(GO:0034451)
0.2 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 1.1 GO:0001740 Barr body(GO:0001740)
0.2 2.8 GO:0031011 Ino80 complex(GO:0031011)
0.2 1.2 GO:0031298 replication fork protection complex(GO:0031298)
0.1 1.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.9 GO:0000922 spindle pole(GO:0000922)
0.1 1.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 6.3 GO:0000786 nucleosome(GO:0000786)
0.1 1.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 4.8 GO:0031941 filamentous actin(GO:0031941)
0.1 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 5.2 GO:0005643 nuclear pore(GO:0005643)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 2.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.7 GO:0016592 mediator complex(GO:0016592)
0.1 1.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 6.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 13.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0016234 inclusion body(GO:0016234)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.5 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.1 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0045178 basal part of cell(GO:0045178)
0.0 6.7 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0044447 axoneme part(GO:0044447)
0.0 0.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 3.6 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 16.8 GO:0043515 kinetochore binding(GO:0043515)
2.7 8.1 GO:0030350 iron-responsive element binding(GO:0030350)
1.7 9.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.6 4.9 GO:0031208 POZ domain binding(GO:0031208)
1.3 9.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 6.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.7 2.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.7 2.7 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.6 1.8 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.5 1.6 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.5 2.9 GO:0051525 NFAT protein binding(GO:0051525)
0.5 0.9 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.4 2.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 2.6 GO:0097016 L27 domain binding(GO:0097016)
0.4 3.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.4 2.9 GO:0034452 dynactin binding(GO:0034452)
0.4 16.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.4 1.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.4 3.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 7.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 1.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 1.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 5.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 1.2 GO:0035877 death effector domain binding(GO:0035877)
0.3 3.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 1.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 4.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.3 2.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 4.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 1.9 GO:0033592 RNA strand annealing activity(GO:0033592)
0.3 3.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 4.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 2.0 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.3 0.8 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 1.0 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 7.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 0.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 1.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 0.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 2.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 8.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 0.8 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 15.1 GO:0031491 nucleosome binding(GO:0031491)
0.2 1.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.8 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.2 4.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.0 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 1.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 4.1 GO:0070410 co-SMAD binding(GO:0070410)
0.2 21.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 23.9 GO:0004386 helicase activity(GO:0004386)
0.2 6.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 16.0 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.3 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.1 GO:0005123 death receptor binding(GO:0005123)
0.1 2.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 2.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 3.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.5 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.4 GO:0070888 E-box binding(GO:0070888)
0.1 2.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 1.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.4 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 3.4 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 2.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 6.4 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 1.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0071949 FAD binding(GO:0071949)
0.1 13.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 13.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 4.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 3.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.9 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 2.9 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 7.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 5.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 3.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 3.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 40.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.7 34.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 9.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.3 8.8 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.3 12.8 PID_PLK1_PATHWAY PLK1 signaling events
0.2 10.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.2 3.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.4 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.1 11.9 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 8.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 3.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 1.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.9 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 3.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 2.7 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 2.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.4 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.5 8.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 3.0 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 2.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 8.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 2.9 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.2 18.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.0 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 5.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.5 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.4 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 2.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 4.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 5.4 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.2 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 1.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.6 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 0.8 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.1 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.7 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 3.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.7 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 3.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 10.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME_GLOBAL_GENOMIC_NER_GG_NER Genes involved in Global Genomic NER (GG-NER)
0.0 2.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 3.2 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.9 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling