Motif ID: Zbtb4
Z-value: 0.704
Transcription factors associated with Zbtb4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zbtb4 | ENSMUSG00000018750.8 | Zbtb4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb4 | mm10_v2_chr11_+_69765899_69765925 | -0.45 | 5.0e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 94 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 8.8 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.5 | 4.2 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.8 | 4.0 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.5 | 4.0 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.9 | 3.4 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.4 | 2.9 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.2 | 2.5 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.5 | 2.3 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 0.1 | 2.3 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 0.0 | 2.1 | GO:0048663 | neuron fate commitment(GO:0048663) |
| 0.1 | 1.8 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.1 | 1.6 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.2 | 1.5 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.2 | 1.5 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 1.5 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 0.2 | 1.4 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.3 | 1.3 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.0 | 1.1 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.1 | 1.0 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.1 | 1.0 | GO:0015693 | magnesium ion transport(GO:0015693) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 38 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.2 | GO:0000145 | exocyst(GO:0000145) |
| 0.2 | 4.0 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 1.1 | 3.4 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.1 | 2.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 2.1 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.9 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 0.9 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.0 | 0.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.8 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 0.7 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.1 | 0.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.6 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 0.0 | 0.6 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 0.5 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.0 | 0.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 0.4 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.0 | 0.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 68 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.2 | 3.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.0 | 3.4 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.7 | 2.9 | GO:0042806 | fucose binding(GO:0042806) |
| 0.5 | 2.5 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.6 | 2.3 | GO:0070976 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
| 0.1 | 2.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 1.6 | GO:0002020 | protease binding(GO:0002020) |
| 0.2 | 1.5 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.2 | 1.5 | GO:0046790 | virion binding(GO:0046790) |
| 0.2 | 1.5 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 1.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 1.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.3 | 1.3 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 1.1 | GO:0030551 | cyclic nucleotide binding(GO:0030551) |
| 0.1 | 1.0 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.1 | 1.0 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 1.0 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 20 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 2.3 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.0 | 1.6 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 1.5 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 1.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 1.4 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 1.2 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.9 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 0.8 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.7 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.0 | 0.7 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.6 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.5 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 0.5 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.4 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.4 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.3 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.3 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.2 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.1 | PID_ALK2_PATHWAY | ALK2 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 26 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 2.5 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 2.3 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 2.2 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.0 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.4 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 1.3 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 0.9 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.0 | 0.9 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.9 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.9 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.8 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 0.7 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.0 | 0.5 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
| 0.0 | 0.5 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.5 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.5 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.4 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
