Motif ID: Zfp148

Z-value: 0.852


Transcription factors associated with Zfp148:

Gene SymbolEntrez IDGene Name
Zfp148 ENSMUSG00000022811.10 Zfp148

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp148mm10_v2_chr16_+_33380765_333807870.473.5e-03Click!


Activity profile for motif Zfp148.

activity profile for motif Zfp148


Sorted Z-values histogram for motif Zfp148

Sorted Z-values for motif Zfp148



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp148

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_70493156 6.539 ENSMUST00000008032.7
 Crlf1
cytokine receptor-like factor 1
chr5_+_17574268 5.744 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 5.560 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_102897123 5.318 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr9_-_98032983 4.649 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr9_-_40455670 3.339 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr11_-_102897146 3.194 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr11_-_54068932 2.551 ENSMUST00000093109.4
ENSMUST00000018755.3
 Pdlim4

PDZ and LIM domain 4

chr11_+_115163333 2.531 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr14_-_25769033 2.334 ENSMUST00000069180.7
 Zcchc24
zinc finger, CCHC domain containing 24
chr6_+_103510874 2.207 ENSMUST00000066905.6
 Chl1
cell adhesion molecule with homology to L1CAM
chr9_-_107667375 2.181 ENSMUST00000010208.8
 Slc38a3
solute carrier family 38, member 3
chr17_-_68004075 2.178 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr10_+_106470281 1.818 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr4_-_149774238 1.706 ENSMUST00000105686.2
 Slc25a33
solute carrier family 25, member 33
chr16_+_17797282 1.700 ENSMUST00000012161.3
 Scarf2
scavenger receptor class F, member 2
chr2_-_104410334 1.682 ENSMUST00000089726.3
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr17_+_79051906 1.632 ENSMUST00000040789.4
 Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr10_-_80329426 1.625 ENSMUST00000020340.8
 Pcsk4
proprotein convertase subtilisin/kexin type 4
chr11_-_72266596 1.608 ENSMUST00000021161.6
ENSMUST00000140167.1
 Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 11.3 GO:0003350 pulmonary myocardium development(GO:0003350)
1.2 8.5 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
1.1 6.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 6.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 2.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 2.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 2.6 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.8 2.5 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.5 2.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 2.2 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.0 2.2 GO:0048747 muscle fiber development(GO:0048747)
0.7 2.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.5 2.1 GO:0015744 succinate transport(GO:0015744)
0.4 2.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.5 2.0 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 1.8 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.4 1.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 1.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 8.5 GO:0097450 astrocyte end-foot(GO:0097450)
2.2 6.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 4.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.2 GO:0016528 sarcoplasm(GO:0016528)
0.1 1.6 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.4 GO:0000791 euchromatin(GO:0000791)
0.2 1.3 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 11.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 8.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.9 6.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 4.7 GO:0002020 protease binding(GO:0002020)
0.1 3.6 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.6 GO:0042805 actinin binding(GO:0042805)
0.2 2.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.7 2.2 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.0 2.2 GO:0051082 unfolded protein binding(GO:0051082)
0.7 2.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 1.9 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.3 1.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 5.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 3.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 2.7 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 2.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 1.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 0.8 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.2 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.2 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.3 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.5 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.0 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.0 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 1.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.8 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 0.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation