Motif ID: Zfp263

Z-value: 0.618


Transcription factors associated with Zfp263:

Gene SymbolEntrez IDGene Name
Zfp263 ENSMUSG00000022529.5 Zfp263

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp263mm10_v2_chr16_+_3744089_37441450.325.5e-02Click!


Activity profile for motif Zfp263.

activity profile for motif Zfp263


Sorted Z-values histogram for motif Zfp263

Sorted Z-values for motif Zfp263



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp263

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_70111920 2.021 ENSMUST00000169074.1
ENSMUST00000021468.7
 Nin

ninein

chr16_-_23988852 1.852 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr5_-_89883321 1.747 ENSMUST00000163159.1
ENSMUST00000061427.5
 Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr15_+_60822947 1.649 ENSMUST00000180730.1
 9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr5_-_39644597 1.602 ENSMUST00000152057.1
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr8_-_11312731 1.587 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr4_+_104367549 1.579 ENSMUST00000106830.2
 Dab1
disabled 1
chr1_-_173942445 1.576 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr5_+_35278566 1.497 ENSMUST00000049545.5
 Adra2c
adrenergic receptor, alpha 2c
chr5_-_39644634 1.483 ENSMUST00000053116.6
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_+_23762003 1.451 ENSMUST00000140583.1
 B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr7_+_49246131 1.372 ENSMUST00000064395.6
 Nav2
neuron navigator 2
chr8_+_11312805 1.326 ENSMUST00000033899.7
 Col4a2
collagen, type IV, alpha 2
chr14_+_101729907 1.233 ENSMUST00000100337.3
 Lmo7
LIM domain only 7
chr1_-_168431896 1.226 ENSMUST00000176540.1
 Pbx1
pre B cell leukemia homeobox 1
chr10_+_13966268 1.216 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr1_-_172297989 1.200 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
 Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr5_-_150594493 1.195 ENSMUST00000016279.7
 N4bp2l1
NEDD4 binding protein 2-like 1
chr16_-_52452465 1.192 ENSMUST00000170035.1
ENSMUST00000164728.1
 Alcam

activated leukocyte cell adhesion molecule

chr1_+_23761749 1.146 ENSMUST00000144602.1
 B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 185 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.4 2.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 2.4 GO:0006813 potassium ion transport(GO:0006813)
0.1 2.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.5 2.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 2.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 2.0 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.6 1.9 GO:0001543 ovarian follicle rupture(GO:0001543)
0.6 1.9 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 1.9 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.3 1.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 1.6 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.5 1.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 1.6 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 1.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 1.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.6 GO:0008542 visual learning(GO:0008542)
0.4 1.5 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.3 1.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.7 GO:0000139 Golgi membrane(GO:0000139)
0.6 3.0 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 2.8 GO:0043196 varicosity(GO:0043196)
0.2 2.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0005657 replication fork(GO:0005657)
0.4 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.4 1.8 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.1 GO:0042825 TAP complex(GO:0042825)
0.1 1.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.1 GO:0097440 apical dendrite(GO:0097440)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)
0.3 0.8 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.8 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 3.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.6 3.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 2.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 1.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 1.9 GO:0008201 heparin binding(GO:0008201)
0.5 1.5 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.0 1.4 GO:0042169 SH2 domain binding(GO:0042169)
0.3 1.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 1.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.8 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 1.7 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.3 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.7 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.2 REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1 4.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.8 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.4 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 1.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.9 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway