Motif ID: Zfp384

Z-value: 1.042


Transcription factors associated with Zfp384:

Gene SymbolEntrez IDGene Name
Zfp384 ENSMUSG00000038346.12 Zfp384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp384mm10_v2_chr6_+_125009665_125009805-0.105.7e-01Click!


Activity profile for motif Zfp384.

activity profile for motif Zfp384


Sorted Z-values histogram for motif Zfp384

Sorted Z-values for motif Zfp384



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp384

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 8.393 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr13_+_94875600 7.304 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr6_-_23248264 4.770 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_34812677 4.557 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr14_-_67715585 4.351 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chr8_-_4779513 3.968 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr19_+_37376359 3.860 ENSMUST00000012587.3
 Kif11
kinesin family member 11
chr16_-_26989974 3.767 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr9_-_91365778 3.645 ENSMUST00000065360.3
 Zic1
zinc finger protein of the cerebellum 1
chr1_+_6487231 3.623 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr18_-_74207771 3.612 ENSMUST00000040188.8
ENSMUST00000177604.1
 Ska1

spindle and kinetochore associated complex subunit 1

chr18_-_84086379 3.576 ENSMUST00000060303.8
 Tshz1
teashirt zinc finger family member 1
chr9_-_91365756 3.435 ENSMUST00000034927.6
 Zic1
zinc finger protein of the cerebellum 1
chr6_+_8948608 3.429 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr12_+_38780284 3.251 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr16_-_22161450 3.246 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_90203980 3.120 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr2_+_165595009 3.098 ENSMUST00000088132.6
 Eya2
eyes absent 2 homolog (Drosophila)
chrX_-_60893430 3.020 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr2_+_5845243 2.989 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 435 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 9.9 GO:0015671 oxygen transport(GO:0015671)
0.2 8.6 GO:0007628 adult walking behavior(GO:0007628)
1.1 6.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 6.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.3 6.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.5 5.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 5.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.6 4.9 GO:0060023 soft palate development(GO:0060023)
0.2 4.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 4.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 4.5 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 4.5 GO:0006334 nucleosome assembly(GO:0006334)
0.4 4.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 4.4 GO:0006270 DNA replication initiation(GO:0006270)
0.3 4.0 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.4 3.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
1.0 3.8 GO:0019323 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.5 3.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 3.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 3.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 181 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.2 GO:0000786 nucleosome(GO:0000786)
0.2 7.9 GO:0005876 spindle microtubule(GO:0005876)
1.0 7.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 4.5 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.4 GO:0005871 kinesin complex(GO:0005871)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.8 GO:0000776 kinetochore(GO:0000776)
0.1 3.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 3.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 3.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.1 3.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.4 3.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 2.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 2.9 GO:0036126 sperm flagellum(GO:0036126)
0.2 2.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 2.7 GO:0070938 contractile ring(GO:0070938)
0.5 2.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 290 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 12.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
2.0 9.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 7.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 5.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 5.4 GO:0003682 chromatin binding(GO:0003682)
1.1 4.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.5 4.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 4.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 4.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 4.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 4.1 GO:0019894 kinesin binding(GO:0019894)
0.2 4.0 GO:0070410 co-SMAD binding(GO:0070410)
0.5 3.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.3 3.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 3.6 GO:0003777 microtubule motor activity(GO:0003777)
0.4 3.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 3.5 GO:0008430 selenium binding(GO:0008430)
1.1 3.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 3.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 PID_PLK1_PATHWAY PLK1 signaling events
0.1 7.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.2 6.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.5 PID_ARF6_PATHWAY Arf6 signaling events
0.1 4.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 4.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 4.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 3.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.6 PID_BARD1_PATHWAY BARD1 signaling events
0.1 2.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 2.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.9 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2 1.7 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.6 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.5 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 1.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.4 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID_FANCONI_PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 9.0 REACTOME_KINESINS Genes involved in Kinesins
0.2 8.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 6.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.6 5.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 4.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 4.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 3.5 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 3.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 2.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.8 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 2.1 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 2.0 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening