Motif ID: Zfp691

Z-value: 0.435


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.651.3e-05Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_119138415 2.990 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr3_-_82074639 1.672 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr5_+_37050854 1.650 ENSMUST00000043794.4
 Jakmip1
janus kinase and microtubule interacting protein 1
chr10_-_86732409 1.540 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr9_-_103761820 1.168 ENSMUST00000049452.8
 Tmem108
transmembrane protein 108
chr8_+_72319033 0.958 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr15_-_12592556 0.946 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr14_+_27238018 0.894 ENSMUST00000049206.5
 Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr1_+_134193432 0.835 ENSMUST00000038445.6
 Mybph
myosin binding protein H
chr2_-_10130638 0.796 ENSMUST00000042290.7
 Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr9_-_21067093 0.728 ENSMUST00000115494.2
 Zglp1
zinc finger, GATA-like protein 1
chr9_+_32696005 0.715 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
 Ets1


E26 avian leukemia oncogene 1, 5' domain


chr3_+_98280427 0.714 ENSMUST00000090746.2
ENSMUST00000120541.1
 Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr13_-_34130345 0.701 ENSMUST00000075774.3
 Tubb2b
tubulin, beta 2B class IIB
chr15_+_82252397 0.695 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr10_+_81183263 0.691 ENSMUST00000047665.6
 Dapk3
death-associated protein kinase 3
chr10_-_81183849 0.558 ENSMUST00000056086.4
 4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr4_-_129623870 0.540 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
 Ccdc28b


coiled coil domain containing 28B


chr5_-_32827109 0.527 ENSMUST00000144673.2
 Gm20671
predicted gene 20671
chr2_+_181715005 0.515 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
 Oprl1


opioid receptor-like 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.6 1.7 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.2 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 1.2 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 1.0 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.2 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.7 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.7 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.2 0.5 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527) forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0097186 amelogenesis(GO:0097186)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.3 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 0.3 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.7 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.7 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis