Motif ID: Zfp784

Z-value: 0.831


Transcription factors associated with Zfp784:

Gene SymbolEntrez IDGene Name
Zfp784 ENSMUSG00000043290.6 Zfp784

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp784mm10_v2_chr7_-_5038427_5038450-0.019.7e-01Click!


Activity profile for motif Zfp784.

activity profile for motif Zfp784


Sorted Z-values histogram for motif Zfp784

Sorted Z-values for motif Zfp784



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp784

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_121495678 7.346 ENSMUST00000035120.4
Cck
cholecystokinin
chr9_-_98032983 5.878 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr9_-_98033181 5.634 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr4_+_48049080 4.665 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr16_-_31314804 4.558 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chr7_-_110862944 4.367 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_-_51567084 3.855 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr5_+_37028329 3.729 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr15_-_71727815 3.634 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr11_+_50602072 3.579 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr17_+_86167777 3.565 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr7_+_48959089 3.472 ENSMUST00000183659.1
Nav2
neuron navigator 2
chr8_+_121730563 3.436 ENSMUST00000026357.5
Jph3
junctophilin 3
chr7_+_123982799 3.421 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr5_+_66745835 3.361 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr5_+_30588078 3.236 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_-_42182163 3.204 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr15_+_92161343 3.093 ENSMUST00000068378.5
Cntn1
contactin 1
chr3_+_8509477 3.028 ENSMUST00000029002.7
Stmn2
stathmin-like 2
chr1_-_40790642 2.970 ENSMUST00000039672.5
Mfsd9
major facilitator superfamily domain containing 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 14.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.7 7.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 6.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 5.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 5.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
1.6 4.7 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.5 4.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.8 4.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 4.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.9 4.4 GO:0051012 microtubule sliding(GO:0051012)
0.4 4.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
1.1 4.2 GO:0035793 cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.9 3.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 3.6 GO:0030574 collagen catabolic process(GO:0030574)
0.9 3.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 3.4 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.4 3.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 3.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
1.0 3.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 3.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.5 GO:0060076 excitatory synapse(GO:0060076)
0.5 7.3 GO:0043203 axon hillock(GO:0043203)
0.0 6.4 GO:0005770 late endosome(GO:0005770)
1.4 5.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 5.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 4.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 4.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 3.5 GO:0005614 interstitial matrix(GO:0005614)
0.7 3.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 3.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.2 3.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197)
0.9 2.6 GO:0045160 myosin I complex(GO:0045160)
0.1 2.5 GO:0031430 M band(GO:0031430)
0.0 2.2 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.8 GO:0015485 cholesterol binding(GO:0015485)
0.5 9.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 8.9 GO:0005509 calcium ion binding(GO:0005509)
1.4 5.8 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 5.1 GO:0030507 spectrin binding(GO:0030507)
0.1 4.8 GO:0070412 R-SMAD binding(GO:0070412)
0.4 4.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 4.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 3.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 3.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.9 3.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 3.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 3.6 GO:0050699 WW domain binding(GO:0050699)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.5 GO:0017124 SH3 domain binding(GO:0017124)
0.2 3.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 3.4 GO:0008201 heparin binding(GO:0008201)
0.5 3.2 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 3.1 GO:0050811 GABA receptor binding(GO:0050811)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 ST_GA12_PATHWAY G alpha 12 Pathway
0.2 3.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 3.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.6 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 2.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 1.7 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 1.6 PID_MYC_PATHWAY C-MYC pathway
0.1 1.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.5 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.0 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.9 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.5 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.6 4.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 4.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 3.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 3.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 3.3 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.2 3.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 3.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 3.0 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 2.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 2.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.9 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis