Motif ID: Zfx_Zfp711

Z-value: 2.945

Transcription factors associated with Zfx_Zfp711:

Gene SymbolEntrez IDGene Name
Zfp711 ENSMUSG00000025529.8 Zfp711
Zfx ENSMUSG00000079509.4 Zfx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfxmm10_v2_chrX_-_94123087_941231590.692.7e-06Click!
Zfp711mm10_v2_chrX_+_112615301_1126153010.289.1e-02Click!


Activity profile for motif Zfx_Zfp711.

activity profile for motif Zfx_Zfp711


Sorted Z-values histogram for motif Zfx_Zfp711

Sorted Z-values for motif Zfx_Zfp711



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfx_Zfp711

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_180225812 16.076 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr2_-_34372004 13.579 ENSMUST00000113132.2
ENSMUST00000040638.8
 Pbx3

pre B cell leukemia homeobox 3

chr4_+_109978004 11.342 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr5_-_115119277 10.994 ENSMUST00000031524.7
 Acads
acyl-Coenzyme A dehydrogenase, short chain
chr2_+_105675478 9.344 ENSMUST00000167211.2
ENSMUST00000111083.3
 Pax6

paired box gene 6

chr19_-_30175414 9.244 ENSMUST00000025778.7
 Gldc
glycine decarboxylase
chr17_-_28350747 9.162 ENSMUST00000080572.7
ENSMUST00000156862.1
 Tead3

TEA domain family member 3

chr9_-_72111827 8.750 ENSMUST00000183404.1
ENSMUST00000184783.1
 Tcf12

transcription factor 12

chr15_-_75747922 8.700 ENSMUST00000062002.4
 Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr6_+_47454320 8.563 ENSMUST00000031697.8
 Cul1
cullin 1
chr8_+_127064107 8.545 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
 Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr2_+_172549581 8.499 ENSMUST00000030391.2
 Tfap2c
transcription factor AP-2, gamma
chr6_-_38876163 8.459 ENSMUST00000161779.1
 Hipk2
homeodomain interacting protein kinase 2
chr17_-_28350600 8.246 ENSMUST00000114799.1
 Tead3
TEA domain family member 3
chr5_-_124095749 8.040 ENSMUST00000031354.4
 Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr11_-_12037391 7.903 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10
chr1_-_135688094 7.789 ENSMUST00000112103.1
 Nav1
neuron navigator 1
chr11_+_60104971 7.785 ENSMUST00000064190.6
 Rai1
retinoic acid induced 1
chr2_-_104816696 7.780 ENSMUST00000117237.1
 Qser1
glutamine and serine rich 1
chr2_+_174110340 7.705 ENSMUST00000044415.9
 Npepl1
aminopeptidase-like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,060 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.1 20.7 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
3.0 17.9 GO:0003383 apical constriction(GO:0003383)
1.6 17.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.1 16.9 GO:0003190 atrioventricular valve formation(GO:0003190)
1.1 16.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
3.9 15.7 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.4 15.7 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.7 15.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
1.1 15.2 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.4 15.1 GO:0007520 myoblast fusion(GO:0007520)
0.5 14.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.0 14.0 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.5 13.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
4.1 12.3 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.7 12.3 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
1.2 12.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
3.0 11.8 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.7 11.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.0 11.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.3 11.3 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 324 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 169.1 GO:0005634 nucleus(GO:0005634)
0.1 127.3 GO:0005654 nucleoplasm(GO:0005654)
0.2 58.6 GO:0005667 transcription factor complex(GO:0005667)
0.4 55.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 42.3 GO:0005694 chromosome(GO:0005694)
0.2 24.6 GO:0000776 kinetochore(GO:0000776)
0.4 23.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.3 22.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.4 19.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
4.7 18.8 GO:0043259 laminin-10 complex(GO:0043259)
0.1 18.5 GO:0043296 apical junction complex(GO:0043296)
1.7 13.3 GO:0033269 internode region of axon(GO:0033269)
0.3 13.3 GO:0005657 replication fork(GO:0005657)
0.2 13.1 GO:0005814 centriole(GO:0005814)
0.1 12.9 GO:0030175 filopodium(GO:0030175)
0.4 12.8 GO:0016592 mediator complex(GO:0016592)
2.5 12.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 12.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.3 12.2 GO:0005925 focal adhesion(GO:0005925)
1.3 11.9 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 542 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 121.7 GO:0003677 DNA binding(GO:0003677)
0.3 66.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 34.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 31.8 GO:0042393 histone binding(GO:0042393)
0.2 29.5 GO:0003714 transcription corepressor activity(GO:0003714)
1.7 26.7 GO:0003680 AT DNA binding(GO:0003680)
0.7 26.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
1.3 24.7 GO:0035497 cAMP response element binding(GO:0035497)
0.5 21.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 20.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 19.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.4 17.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.3 17.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 16.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.9 16.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
2.1 16.5 GO:0046790 virion binding(GO:0046790)
0.4 15.4 GO:0030332 cyclin binding(GO:0030332)
0.6 14.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.6 14.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 13.8 GO:0004386 helicase activity(GO:0004386)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 54.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.5 34.4 PID_E2F_PATHWAY E2F transcription factor network
0.4 23.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.8 23.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
2.7 21.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 20.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.4 20.1 PID_PLK1_PATHWAY PLK1 signaling events
0.8 20.0 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.3 18.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 18.0 PID_CDC42_PATHWAY CDC42 signaling events
0.4 17.7 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
1.2 16.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 14.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.3 14.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.4 14.6 PID_BMP_PATHWAY BMP receptor signaling
0.5 14.1 PID_BARD1_PATHWAY BARD1 signaling events
0.5 13.2 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.3 10.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.6 10.0 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 10.0 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 139 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 50.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
1.3 42.8 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
1.2 38.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.9 31.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
1.5 29.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.8 25.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.8 23.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.7 21.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.7 20.8 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.4 15.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.9 15.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.6 14.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 13.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.8 12.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.6 11.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.7 11.0 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 9.7 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.8 8.8 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.4 8.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.1 8.5 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex