Motif ID: Zic3

Z-value: 0.965


Transcription factors associated with Zic3:

Gene SymbolEntrez IDGene Name
Zic3 ENSMUSG00000067860.5 Zic3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic3mm10_v2_chrX_+_58030999_580310180.865.2e-12Click!


Activity profile for motif Zic3.

activity profile for motif Zic3


Sorted Z-values histogram for motif Zic3

Sorted Z-values for motif Zic3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_53159885 5.269 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_127800604 3.767 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr7_+_51879041 3.405 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr1_-_119053339 3.214 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr8_+_127064107 3.131 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr17_+_86963279 3.093 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr2_+_172550991 3.070 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr4_+_108165449 3.055 ENSMUST00000116309.3
ENSMUST00000116307.1
Echdc2

enoyl Coenzyme A hydratase domain containing 2

chr5_-_98030727 3.012 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr9_+_91378636 2.964 ENSMUST00000066384.5
Zic4
zinc finger protein of the cerebellum 4
chr5_+_137758133 2.952 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr7_+_51878967 2.925 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr1_+_135729147 2.869 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr4_+_108165432 2.788 ENSMUST00000052999.6
Echdc2
enoyl Coenzyme A hydratase domain containing 2
chr6_-_56362356 2.779 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chrX_+_56454871 2.707 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr5_+_135725713 2.628 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr13_+_44729535 2.582 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr13_-_29984219 2.576 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr11_-_34833631 2.507 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr13_-_95891905 2.494 ENSMUST00000068603.6
Iqgap2
IQ motif containing GTPase activating protein 2
chr5_-_114273702 2.348 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr2_-_180776900 2.345 ENSMUST00000108878.1
Bhlhe23
basic helix-loop-helix family, member e23
chr8_+_127064022 2.280 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr13_+_44730726 2.232 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr2_-_104816696 2.221 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr14_+_31217850 2.192 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr6_+_61180313 2.121 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr4_+_141010644 2.056 ENSMUST00000071977.8
Mfap2
microfibrillar-associated protein 2
chrX_+_161717498 2.025 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr2_-_160872985 2.015 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr11_-_100354040 1.976 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr12_+_112620030 1.948 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr9_-_103480328 1.942 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr7_-_48881032 1.930 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr14_-_54926784 1.912 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr12_-_27342696 1.896 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr2_+_156840966 1.888 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr2_-_127482499 1.875 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chr4_+_52439235 1.815 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr8_+_127063893 1.771 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr11_+_102604370 1.751 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr5_+_139543889 1.711 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chrX_-_108834303 1.706 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr9_-_82975475 1.703 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr10_+_18845071 1.694 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr2_-_39190687 1.641 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr14_-_73325773 1.594 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr9_+_85842852 1.593 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chrY_-_1286563 1.573 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr4_-_62208426 1.573 ENSMUST00000068822.3
Zfp37
zinc finger protein 37
chr2_+_120629113 1.553 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr2_+_131234043 1.535 ENSMUST00000041362.5
ENSMUST00000110199.2
Mavs

mitochondrial antiviral signaling protein

chr15_-_99820072 1.526 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr14_-_31640878 1.499 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr7_-_49636847 1.486 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chrX_+_140956892 1.484 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr10_-_81349085 1.480 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr11_+_97030130 1.443 ENSMUST00000153482.1
Scrn2
secernin 2
chrX_+_137049586 1.440 ENSMUST00000047852.7
Fam199x
family with sequence similarity 199, X-linked
chr2_-_160872552 1.419 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr3_-_108415552 1.383 ENSMUST00000090558.3
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr13_-_81633119 1.382 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr5_+_115506668 1.382 ENSMUST00000067268.8
ENSMUST00000086523.3
Pxn

paxillin

chr2_-_160872829 1.374 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr14_-_37098211 1.371 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr10_-_49788743 1.349 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr17_+_86963077 1.322 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr11_+_72042455 1.312 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr19_+_7268296 1.308 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr12_+_89812467 1.296 ENSMUST00000110133.2
ENSMUST00000110130.2
Nrxn3

neurexin III

chr4_+_108460000 1.294 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr15_+_40655020 1.293 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr2_+_15055274 1.292 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr7_-_70360593 1.289 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr11_-_48826655 1.284 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr8_-_18950932 1.270 ENSMUST00000055503.5
ENSMUST00000095438.3
Xkr5

X Kell blood group precursor-related family, member 5

chr19_+_6975048 1.263 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_98149551 1.250 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr14_+_54476100 1.240 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr7_-_109439076 1.212 ENSMUST00000106745.2
ENSMUST00000090414.4
Stk33

serine/threonine kinase 33

chr2_+_156840077 1.209 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr11_+_97029925 1.208 ENSMUST00000021249.4
Scrn2
secernin 2
chrX_+_10717390 1.182 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr6_+_146577859 1.163 ENSMUST00000067404.6
ENSMUST00000111663.2
ENSMUST00000058245.4
Fgfr1op2


FGFR1 oncogene partner 2


chr3_-_102204576 1.152 ENSMUST00000159388.1
Vangl1
vang-like 1 (van gogh, Drosophila)
chr14_-_48665098 1.146 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr4_-_154097105 1.127 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr7_+_127800844 1.123 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr2_+_84840612 1.118 ENSMUST00000111625.1
Slc43a1
solute carrier family 43, member 1
chr7_-_109438998 1.094 ENSMUST00000121378.1
Stk33
serine/threonine kinase 33
chr13_-_47105790 1.088 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr7_-_4778141 1.079 ENSMUST00000094892.5
Il11
interleukin 11
chrY_-_1245685 1.064 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr6_+_86404336 1.054 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr6_-_146577825 1.047 ENSMUST00000032427.8
Asun
asunder, spermatogenesis regulator
chr9_-_77544870 1.044 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr6_+_86404219 1.041 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chrX_+_10717451 1.039 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr2_+_127008711 1.033 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chrX_+_163909132 1.030 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr6_-_101377342 1.019 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr11_-_72266596 1.014 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr3_+_87930256 1.013 ENSMUST00000055984.6
Isg20l2
interferon stimulated exonuclease gene 20-like 2
chr2_-_170427828 1.010 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr17_+_14279506 1.010 ENSMUST00000024660.8
Smoc2
SPARC related modular calcium binding 2
chr19_+_46396885 1.003 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
Sufu


suppressor of fused homolog (Drosophila)


chr6_+_86404257 1.002 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chrX_+_37126777 0.995 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr9_-_77544829 0.980 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr19_+_46397009 0.978 ENSMUST00000118440.1
Sufu
suppressor of fused homolog (Drosophila)
chr6_-_39725448 0.978 ENSMUST00000002487.8
Braf
Braf transforming gene
chr14_-_56811464 0.965 ENSMUST00000173954.1
Zmym5
zinc finger, MYM-type 5
chr9_-_32344237 0.960 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr8_-_87959560 0.952 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr19_-_4615453 0.941 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr16_+_37011758 0.937 ENSMUST00000071452.5
ENSMUST00000054034.6
Polq

polymerase (DNA directed), theta

chr3_+_103279293 0.935 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr14_-_34374617 0.924 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr2_-_20968526 0.924 ENSMUST00000141298.2
ENSMUST00000125783.2
Arhgap21

Rho GTPase activating protein 21

chr8_+_4248188 0.919 ENSMUST00000110993.1
Gm14378
predicted gene 14378
chr2_-_122369130 0.909 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr16_+_32332238 0.906 ENSMUST00000115151.3
Ubxn7
UBX domain protein 7
chr16_-_91044473 0.894 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr11_-_100759740 0.892 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr10_-_63023847 0.890 ENSMUST00000119814.2
Hnrnph3
heterogeneous nuclear ribonucleoprotein H3
chrY_-_1245753 0.885 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr3_+_86224665 0.883 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr5_+_92137896 0.879 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chrX_+_71050160 0.873 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr7_-_109438786 0.871 ENSMUST00000121748.1
Stk33
serine/threonine kinase 33
chrX_+_73639414 0.870 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr14_+_31001414 0.867 ENSMUST00000022476.7
Glt8d1
glycosyltransferase 8 domain containing 1
chr14_+_31001383 0.848 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr2_+_174110340 0.847 ENSMUST00000044415.9
Npepl1
aminopeptidase-like 1
chr12_-_21373550 0.838 ENSMUST00000101551.3
Adam17
a disintegrin and metallopeptidase domain 17
chr10_-_95324072 0.833 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr12_-_111813834 0.824 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr12_-_21373606 0.820 ENSMUST00000064536.6
Adam17
a disintegrin and metallopeptidase domain 17
chr11_+_116280939 0.817 ENSMUST00000055872.2
Galr2
galanin receptor 2
chr14_-_56811716 0.808 ENSMUST00000039812.9
ENSMUST00000111285.2
Zmym5

zinc finger, MYM-type 5

chr4_+_131873608 0.805 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr18_-_67724560 0.798 ENSMUST00000120934.1
ENSMUST00000025420.7
ENSMUST00000122412.1
Ptpn2


protein tyrosine phosphatase, non-receptor type 2


chr19_+_3767953 0.798 ENSMUST00000113970.1
Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr9_+_46012810 0.787 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr2_-_119477613 0.784 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr19_-_4839286 0.760 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr13_+_96542727 0.745 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr11_-_54068932 0.742 ENSMUST00000093109.4
ENSMUST00000018755.3
Pdlim4

PDZ and LIM domain 4

chr10_-_127522428 0.740 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chrX_+_7762652 0.734 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
Tfe3



transcription factor E3



chr2_-_151009364 0.730 ENSMUST00000109896.1
Ninl
ninein-like
chr12_-_102704896 0.726 ENSMUST00000178697.1
ENSMUST00000046518.5
Itpk1

inositol 1,3,4-triphosphate 5/6 kinase

chr11_+_96789118 0.726 ENSMUST00000018810.3
Cbx1
chromobox 1
chr9_-_123678873 0.712 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr17_+_25786566 0.708 ENSMUST00000095500.4
Ccdc78
coiled-coil domain containing 78
chr12_+_83632208 0.708 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
Rbm25




RNA binding motif protein 25




chr18_-_84951477 0.695 ENSMUST00000025547.2
Timm21
tranlocase of inner mitochondrial membrane 21
chr7_-_132852606 0.682 ENSMUST00000120425.1
Mettl10
methyltransferase like 10
chr12_+_84316830 0.682 ENSMUST00000045931.10
Zfp410
zinc finger protein 410
chr11_+_96789213 0.679 ENSMUST00000079702.3
Cbx1
chromobox 1
chr11_+_96789149 0.668 ENSMUST00000093943.3
Cbx1
chromobox 1
chr7_-_132852657 0.667 ENSMUST00000033257.8
Mettl10
methyltransferase like 10
chrX_+_57053549 0.649 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr8_-_47289394 0.642 ENSMUST00000079195.5
Stox2
storkhead box 2
chr17_-_12507704 0.639 ENSMUST00000024595.2
Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr10_+_81137953 0.619 ENSMUST00000117956.1
Zbtb7a
zinc finger and BTB domain containing 7a
chr11_-_109473220 0.618 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr6_+_52713729 0.615 ENSMUST00000080723.4
ENSMUST00000149588.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr17_+_4994904 0.614 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chrX_+_71663665 0.611 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr1_+_166254095 0.609 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr11_+_67078293 0.609 ENSMUST00000108689.1
ENSMUST00000165221.1
ENSMUST00000007301.7
Myh3


myosin, heavy polypeptide 3, skeletal muscle, embryonic


chr6_+_48395586 0.607 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
Krba1


KRAB-A domain containing 1


chr14_-_55560340 0.603 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr11_+_60537978 0.600 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr11_-_70687917 0.593 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr6_+_48395652 0.587 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr2_-_146511899 0.587 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr10_-_78487842 0.580 ENSMUST00000069431.4
Gm9978
predicted gene 9978
chr11_+_79339792 0.576 ENSMUST00000108251.2
ENSMUST00000071325.2
Nf1

neurofibromatosis 1

chr5_+_93093428 0.575 ENSMUST00000074733.7
Sept11
septin 11
chr9_+_55149364 0.571 ENSMUST00000121677.1
Ube2q2
ubiquitin-conjugating enzyme E2Q (putative) 2
chr1_-_64121456 0.570 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr1_+_91366412 0.570 ENSMUST00000086861.5
Fam132b
family with sequence similarity 132, member B
chr4_+_43632185 0.563 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr6_+_7844806 0.559 ENSMUST00000040159.4
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr14_+_75845296 0.552 ENSMUST00000142061.1
Tpt1
tumor protein, translationally-controlled 1
chrX_+_52791179 0.546 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr6_+_52714219 0.542 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr11_+_53519871 0.539 ENSMUST00000120878.2
Sept8
septin 8
chr1_+_187609028 0.538 ENSMUST00000110939.1
Esrrg
estrogen-related receptor gamma
chr9_+_66060169 0.535 ENSMUST00000034947.5
Ppib
peptidylprolyl isomerase B
chr1_-_58586191 0.531 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr13_+_6548154 0.528 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr7_-_105787544 0.523 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr1_+_191906743 0.523 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr5_+_12383156 0.521 ENSMUST00000030868.6
Sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr4_+_19605451 0.520 ENSMUST00000108250.2
Gm12353
predicted gene 12353
chrX_+_71364901 0.519 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0055099 response to high density lipoprotein particle(GO:0055099)
1.2 7.2 GO:0003383 apical constriction(GO:0003383)
1.0 3.1 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.8 3.2 GO:0060032 notochord regression(GO:0060032)
0.7 4.9 GO:0035754 B cell chemotaxis(GO:0035754)
0.7 2.6 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.6 2.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.6 1.9 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.6 1.9 GO:0060023 soft palate development(GO:0060023)
0.6 2.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.5 1.6 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.5 1.5 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.5 2.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.5 1.4 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 1.3 GO:0003195 tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.4 2.0 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.4 4.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 2.2 GO:0002934 desmosome organization(GO:0002934)
0.4 1.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.4 1.8 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
0.3 3.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 0.3 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.3 3.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 0.9 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) regulation of catecholamine secretion(GO:0050433)
0.3 1.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.5 GO:0051697 protein delipidation(GO:0051697)
0.3 1.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 3.8 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.3 1.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3 0.8 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.3 1.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 0.3 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.3 1.0 GO:0015744 succinate transport(GO:0015744)
0.2 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 1.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.9 GO:0010288 response to lead ion(GO:0010288)
0.2 1.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 0.6 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.2 0.8 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 1.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 1.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.0 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 2.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.7 GO:0006545 glycine biosynthetic process(GO:0006545)
0.2 0.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 2.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 4.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 0.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 0.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 1.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 1.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 0.6 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 3.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.6 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 1.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 1.6 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 1.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.5 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.3 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 2.1 GO:0030220 platelet formation(GO:0030220)
0.1 1.0 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.9 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 1.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.9 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.2 GO:0097402 neuroblast migration(GO:0097402)
0.1 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.9 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.2 GO:2001016 heparan sulfate proteoglycan catabolic process(GO:0030200) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1 0.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 1.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 3.3 GO:1901998 toxin transport(GO:1901998)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 5.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 4.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 2.2 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.1 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 2.9 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.5 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.3 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 1.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.9 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 1.0 GO:0046638 positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.0 0.9 GO:0045056 transcytosis(GO:0045056)
0.0 0.7 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0061525 hindgut development(GO:0061525)
0.0 1.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.8 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.5 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 1.2 GO:0031529 ruffle organization(GO:0031529)
0.0 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.4 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 1.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.0 1.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.0 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 1.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0071372 response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0090292 nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.2 GO:0033269 internode region of axon(GO:0033269)
0.4 1.5 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 3.1 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 2.1 GO:0001940 male pronucleus(GO:0001940)
0.3 5.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 3.2 GO:0097542 ciliary tip(GO:0097542)
0.2 1.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 2.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 0.7 GO:0070552 BRISC complex(GO:0070552)
0.2 1.8 GO:0000796 condensin complex(GO:0000796)
0.2 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 2.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.6 GO:0045298 tubulin complex(GO:0045298)
0.1 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.0 2.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 4.1 GO:0005938 cell cortex(GO:0005938)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0045177 apical part of cell(GO:0045177)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.8 4.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.7 2.6 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.5 2.5 GO:0043515 kinetochore binding(GO:0043515)
0.4 5.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.4 2.1 GO:0070051 fibrinogen binding(GO:0070051)
0.4 2.8 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 4.4 GO:0005522 profilin binding(GO:0005522)
0.3 1.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.3 1.5 GO:0050700 CARD domain binding(GO:0050700)
0.3 1.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 0.8 GO:0097677 STAT family protein binding(GO:0097677)
0.3 1.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 2.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 0.7 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 0.7 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 2.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 2.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 1.0 GO:0045545 syndecan binding(GO:0045545)
0.2 1.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 2.7 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 1.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 7.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 0.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.8 GO:0097001 ceramide binding(GO:0097001)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 3.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 3.1 GO:0032452 histone demethylase activity(GO:0032452)
0.1 2.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.1 8.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.6 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 9.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0048406 neurotrophin binding(GO:0043121) nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 1.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 4.3 GO:0001047 core promoter binding(GO:0001047)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.0 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.8 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.8 GO:0008017 microtubule binding(GO:0008017)
0.0 1.1 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 2.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 3.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 7.2 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 7.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 3.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 4.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.4 PID_IGF1_PATHWAY IGF1 pathway
0.1 0.9 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 4.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 2.2 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 2.5 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events
0.0 3.0 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.1 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.8 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.9 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 5.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 7.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 6.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 2.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 4.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.0 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.5 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.6 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.9 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.0 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.8 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.2 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 2.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.3 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway