Motif ID: Zkscan1

Z-value: 0.558


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.334.5e-02Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_56969864 4.404 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr15_+_83779999 4.118 ENSMUST00000046168.5
Mpped1
metallophosphoesterase domain containing 1
chr1_-_56969827 3.524 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr12_+_73997749 3.162 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr15_-_75048837 2.913 ENSMUST00000179762.1
ENSMUST00000065408.9
Ly6c1

lymphocyte antigen 6 complex, locus C1

chr19_-_61228396 2.699 ENSMUST00000076046.6
Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr7_+_112225856 2.496 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr4_+_129960760 2.152 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr14_-_30353468 1.912 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_+_103619580 1.752 ENSMUST00000106827.1
Dab1
disabled 1
chr17_+_28575718 1.693 ENSMUST00000080780.6
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr4_+_42922253 1.691 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr15_-_79164477 1.687 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr11_-_61453992 1.502 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
Rnf112


ring finger protein 112


chr10_-_83337845 1.479 ENSMUST00000039956.5
Slc41a2
solute carrier family 41, member 2
chr11_+_19924403 1.447 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr12_-_76818374 1.446 ENSMUST00000118604.1
Rab15
RAB15, member RAS oncogene family
chr1_+_50927511 1.418 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_+_19924354 1.415 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chr15_-_74997634 1.321 ENSMUST00000023248.6
Ly6a
lymphocyte antigen 6 complex, locus A
chr4_+_74013442 1.254 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr3_+_62338344 1.219 ENSMUST00000079300.6
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_+_44310213 1.159 ENSMUST00000107938.1
Shank1
SH3/ankyrin domain gene 1
chr12_+_109545390 0.959 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr9_+_106368594 0.931 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr1_+_171840607 0.930 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr4_+_101419277 0.897 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4


adenylate kinase 4


chr18_-_52529847 0.779 ENSMUST00000171470.1
Lox
lysyl oxidase
chr12_+_88360801 0.773 ENSMUST00000166940.1
Adck1
aarF domain containing kinase 1
chr17_+_24886643 0.747 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr7_-_118491912 0.740 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr12_-_79007276 0.693 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr4_-_116144609 0.685 ENSMUST00000030469.4
Lurap1
leucine rich adaptor protein 1
chr5_+_125441546 0.671 ENSMUST00000049040.9
Bri3bp
Bri3 binding protein
chr5_-_70842617 0.669 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr8_+_70527829 0.663 ENSMUST00000119698.1
Fkbp8
FK506 binding protein 8
chr8_+_70527724 0.662 ENSMUST00000119353.2
ENSMUST00000075491.7
Fkbp8

FK506 binding protein 8

chr7_-_98162318 0.654 ENSMUST00000107112.1
Capn5
calpain 5
chr4_+_126262325 0.641 ENSMUST00000030660.8
Trappc3
trafficking protein particle complex 3
chrX_+_20870166 0.639 ENSMUST00000115342.3
ENSMUST00000009530.4
Timp1

tissue inhibitor of metalloproteinase 1

chr2_+_112261926 0.632 ENSMUST00000028553.3
Nop10
NOP10 ribonucleoprotein
chr15_-_75111684 0.631 ENSMUST00000100542.3
Ly6c2
lymphocyte antigen 6 complex, locus C2
chr18_+_61105844 0.626 ENSMUST00000115268.3
Csf1r
colony stimulating factor 1 receptor
chr10_-_39122277 0.621 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr4_-_47057296 0.575 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr4_+_138972885 0.556 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4


transmembrane and coiled-coil domains 4


chr11_+_28853189 0.549 ENSMUST00000020759.5
Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr19_+_10525244 0.533 ENSMUST00000038379.3
Cpsf7
cleavage and polyadenylation specific factor 7
chr19_+_28963892 0.521 ENSMUST00000045674.2
Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr18_+_53245618 0.508 ENSMUST00000165032.1
Snx24
sorting nexing 24
chr5_-_8367982 0.504 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr10_+_90829835 0.489 ENSMUST00000179964.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_109722214 0.482 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr10_+_90829409 0.458 ENSMUST00000182202.1
ENSMUST00000182966.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr4_-_133277730 0.448 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr17_+_87107621 0.442 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr19_-_53944621 0.439 ENSMUST00000135402.2
Bbip1
BBSome interacting protein 1
chr10_+_90829538 0.433 ENSMUST00000179694.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_10525201 0.417 ENSMUST00000025570.6
Sdhaf2
succinate dehydrogenase complex assembly factor 2
chr2_-_156839790 0.399 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr11_+_78826575 0.398 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chr10_+_90829780 0.384 ENSMUST00000179337.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_57147034 0.382 ENSMUST00000034842.4
Neil1
nei endonuclease VIII-like 1 (E. coli)
chr9_+_45042425 0.381 ENSMUST00000034600.4
Mpzl2
myelin protein zero-like 2
chr15_-_78572754 0.380 ENSMUST00000043214.6
Rac2
RAS-related C3 botulinum substrate 2
chr12_-_72664759 0.371 ENSMUST00000021512.9
Dhrs7
dehydrogenase/reductase (SDR family) member 7
chr8_-_70527945 0.371 ENSMUST00000138260.1
ENSMUST00000117580.1
Kxd1

KxDL motif containing 1

chr9_-_110742577 0.362 ENSMUST00000006005.7
Pth1r
parathyroid hormone 1 receptor
chr18_+_53245736 0.359 ENSMUST00000025417.8
Snx24
sorting nexing 24
chr18_+_14424821 0.349 ENSMUST00000069552.5
Gm5160
predicted gene 5160
chr4_-_141078302 0.348 ENSMUST00000030760.8
Necap2
NECAP endocytosis associated 2
chr11_+_59662471 0.341 ENSMUST00000072031.6
ENSMUST00000116371.1
ENSMUST00000108751.1
ENSMUST00000066330.8
Mprip



myosin phosphatase Rho interacting protein



chr15_-_76656905 0.339 ENSMUST00000176274.1
Cyhr1
cysteine and histidine rich 1
chr2_-_80129458 0.329 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr8_-_70527645 0.328 ENSMUST00000132867.1
Kxd1
KxDL motif containing 1
chr7_-_28962265 0.321 ENSMUST00000068045.7
Actn4
actinin alpha 4
chr7_-_28962223 0.309 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr2_+_31245801 0.297 ENSMUST00000000199.7
Ncs1
neuronal calcium sensor 1
chr10_-_81545175 0.279 ENSMUST00000043604.5
Gna11
guanine nucleotide binding protein, alpha 11
chr17_-_33718591 0.273 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
March2




membrane-associated ring finger (C3HC4) 2




chr11_-_69981242 0.225 ENSMUST00000108594.1
Elp5
elongator acetyltransferase complex subunit 5
chr11_+_78512193 0.208 ENSMUST00000001127.4
Poldip2
polymerase (DNA-directed), delta interacting protein 2
chr4_-_134915010 0.203 ENSMUST00000105863.1
ENSMUST00000030626.5
Tmem50a

transmembrane protein 50A

chr2_+_55411790 0.179 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chrX_+_164373363 0.178 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr2_-_27248335 0.176 ENSMUST00000139312.1
Sardh
sarcosine dehydrogenase
chr10_+_80053488 0.174 ENSMUST00000105372.1
Gpx4
glutathione peroxidase 4
chr16_-_10447340 0.171 ENSMUST00000051118.6
Tvp23a
trans-golgi network vesicle protein 23A
chr15_+_16778101 0.163 ENSMUST00000026432.6
Cdh9
cadherin 9
chr11_+_69981127 0.163 ENSMUST00000108593.1
Ctdnep1
CTD nuclear envelope phosphatase 1
chr11_-_120457936 0.143 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr1_+_87326997 0.137 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr4_+_141444654 0.129 ENSMUST00000006377.6
Zbtb17
zinc finger and BTB domain containing 17
chr6_+_47877204 0.127 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr12_-_111574384 0.120 ENSMUST00000180698.1
2810029C07Rik
RIKEN cDNA 2810029C07 gene
chr9_+_44499126 0.111 ENSMUST00000074989.5
Bcl9l
B cell CLL/lymphoma 9-like
chr18_+_31609512 0.100 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr1_+_87327008 0.097 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr3_-_146108047 0.092 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr6_-_122340525 0.088 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_+_29134854 0.085 ENSMUST00000161522.1
ENSMUST00000159975.1
ENSMUST00000032811.5
ENSMUST00000094617.4
Rasgrp4



RAS guanyl releasing protein 4



chr19_+_53944870 0.063 ENSMUST00000025932.7
Shoc2
soc-2 (suppressor of clear) homolog (C. elegans)
chr11_-_47379405 0.062 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr11_-_78512105 0.062 ENSMUST00000052566.7
Tmem199
transmembrane protein 199
chr1_-_93635692 0.056 ENSMUST00000027498.7
Stk25
serine/threonine kinase 25 (yeast)
chr1_+_90603425 0.032 ENSMUST00000036153.5
Cops8
COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana)
chr6_-_122340499 0.030 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr13_-_53473074 0.029 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr18_-_6490808 0.025 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr5_-_134229581 0.024 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
Ncf1


neutrophil cytosolic factor 1


chr4_+_131921771 0.020 ENSMUST00000094666.3
Tmem200b
transmembrane protein 200B
chr12_+_85110833 0.017 ENSMUST00000053811.8
Dlst
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr9_+_119357381 0.004 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr17_+_45506825 0.003 ENSMUST00000024733.7
Aars2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr7_+_24370255 0.002 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.5 2.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.5 7.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 1.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 1.4 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.3 1.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 0.9 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.2 2.7 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 2.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 0.6 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 1.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 1.2 GO:0046959 habituation(GO:0046959)
0.1 1.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:1903975 regulation of glial cell migration(GO:1903975)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 1.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.3 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.9 GO:0046033 AMP metabolic process(GO:0046033)
0.0 1.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 1.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.3 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 3.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 7.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.1 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 0.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.5 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.1 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 3.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0017046 peptide hormone binding(GO:0017046)
0.0 3.3 GO:0003924 GTPase activity(GO:0003924)
0.0 1.8 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.9 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 1.3 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 PID_IL4_2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.9 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse