Motif ID: Zkscan3

Z-value: 0.286


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_214027550.086.2e-01Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_100786402 0.711 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr11_-_75422586 0.416 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr2_+_104095796 0.357 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr3_+_146500071 0.339 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr4_+_156026120 0.323 ENSMUST00000103173.3
 Tnfrsf18
tumor necrosis factor receptor superfamily, member 18
chr3_+_79629074 0.307 ENSMUST00000029388.8
 4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr5_-_88675613 0.284 ENSMUST00000113234.1
ENSMUST00000153565.1
 Grsf1

G-rich RNA sequence binding factor 1

chr3_+_146499850 0.256 ENSMUST00000118280.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr10_-_33951190 0.216 ENSMUST00000048222.4
 Zufsp
zinc finger with UFM1-specific peptidase domain
chrX_-_17571563 0.215 ENSMUST00000177213.1
 Fundc1
FUN14 domain containing 1
chrX_-_17572241 0.188 ENSMUST00000176638.1
ENSMUST00000026016.6
 Fundc1

FUN14 domain containing 1

chr5_+_24985840 0.179 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr11_-_75422524 0.178 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr5_-_88675190 0.174 ENSMUST00000133532.1
ENSMUST00000150438.1
 Grsf1

G-rich RNA sequence binding factor 1

chr8_+_33732237 0.170 ENSMUST00000171010.1
 Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr14_+_51893610 0.169 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr13_-_19395728 0.167 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr1_+_132298606 0.156 ENSMUST00000046071.4
 Klhdc8a
kelch domain containing 8A
chr2_+_104069819 0.156 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
 Cd59b


CD59b antigen


chr12_+_76533540 0.154 ENSMUST00000075249.4
 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_95687846 0.151 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
 Adamtsl4


ADAMTS-like 4


chrX_-_75874536 0.148 ENSMUST00000033547.7
 Pls3
plastin 3 (T-isoform)
chr1_+_180942452 0.148 ENSMUST00000027800.8
 Tmem63a
transmembrane protein 63a
chr7_+_101896340 0.137 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr15_-_3979432 0.134 ENSMUST00000022791.8
 Fbxo4
F-box protein 4
chr4_+_156026304 0.128 ENSMUST00000040274.7
ENSMUST00000122001.1
 Tnfrsf18

tumor necrosis factor receptor superfamily, member 18

chr13_+_104109737 0.123 ENSMUST00000044385.7
 Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr2_-_66634952 0.112 ENSMUST00000100064.2
ENSMUST00000100063.2
 Scn9a

sodium channel, voltage-gated, type IX, alpha

chr13_+_44730726 0.102 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
 Jarid2


jumonji, AT rich interactive domain 2


chr1_-_173333503 0.101 ENSMUST00000038227.4
 Darc
Duffy blood group, chemokine receptor
chr4_+_63544747 0.099 ENSMUST00000035301.6
 Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr2_+_121171155 0.097 ENSMUST00000110658.1
 Tubgcp4
tubulin, gamma complex associated protein 4
chr6_-_43666158 0.096 ENSMUST00000114644.2
ENSMUST00000150599.1
ENSMUST00000067888.7
 Tpk1


thiamine pyrophosphokinase


chr11_-_102365111 0.093 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr1_+_135232045 0.085 ENSMUST00000110798.3
 Gm4204
predicted gene 4204
chr12_+_69724939 0.084 ENSMUST00000021372.5
 Atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr2_-_30194112 0.080 ENSMUST00000113659.1
ENSMUST00000113660.1
 Ccbl1

cysteine conjugate-beta lyase 1

chr7_+_126759601 0.079 ENSMUST00000050201.4
ENSMUST00000057669.9
 Mapk3

mitogen-activated protein kinase 3

chr7_-_81345189 0.079 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr14_+_57424054 0.077 ENSMUST00000122063.1
 Ift88
intraflagellar transport 88
chr8_-_70760889 0.076 ENSMUST00000038626.8
 Mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr2_+_121295437 0.071 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr12_+_112588753 0.070 ENSMUST00000101029.2
 Inf2
inverted formin, FH2 and WH2 domain containing
chr12_-_69724830 0.069 ENSMUST00000021370.8
 L2hgdh
L-2-hydroxyglutarate dehydrogenase
chr7_-_127020321 0.065 ENSMUST00000032918.2
 Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr11_-_102218923 0.064 ENSMUST00000131254.1
 Hdac5
histone deacetylase 5
chr4_+_15957923 0.062 ENSMUST00000029879.8
ENSMUST00000149069.1
 Nbn

nibrin

chr13_+_104109752 0.062 ENSMUST00000160322.1
ENSMUST00000159574.1
 Sgtb

small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta

chr1_+_37997975 0.057 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr9_+_114688782 0.057 ENSMUST00000047404.6
 Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr18_+_67800101 0.054 ENSMUST00000025425.5
 Cep192
centrosomal protein 192
chr11_-_100650693 0.054 ENSMUST00000103119.3
 Zfp385c
zinc finger protein 385C
chr13_-_38658991 0.053 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr8_+_70616816 0.041 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr2_+_121171204 0.040 ENSMUST00000039541.5
ENSMUST00000110657.1
 Tubgcp4

tubulin, gamma complex associated protein 4

chr18_+_61105844 0.039 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr1_+_58795371 0.037 ENSMUST00000027189.8
 Casp8
caspase 8
chr11_+_35769462 0.036 ENSMUST00000018990.7
 Pank3
pantothenate kinase 3
chr2_+_156613664 0.036 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr6_+_125552948 0.035 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr8_+_71396853 0.033 ENSMUST00000002473.8
 Babam1
BRISC and BRCA1 A complex member 1
chr3_-_63929376 0.028 ENSMUST00000061706.6
 E130311K13Rik
RIKEN cDNA E130311K13 gene
chr8_+_31091593 0.024 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr13_-_32851176 0.017 ENSMUST00000091668.5
ENSMUST00000076352.6
 Serpinb1a

serine (or cysteine) peptidase inhibitor, clade B, member 1a

chr2_+_32646586 0.013 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr5_+_24586721 0.012 ENSMUST00000121863.1
ENSMUST00000088295.4
 Chpf2

chondroitin polymerizing factor 2

chr12_+_32954179 0.011 ENSMUST00000020885.6
 Sypl
synaptophysin-like protein
chr1_-_39651165 0.006 ENSMUST00000053355.4
 Creg2
cellular repressor of E1A-stimulated genes 2
chr17_+_46110982 0.002 ENSMUST00000024763.3
ENSMUST00000123646.1
 Mrps18a

mitochondrial ribosomal protein S18A

chr8_-_106893581 0.001 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
 Chtf8



CTF8, chromosome transmission fidelity factor 8



chr10_+_80629646 0.001 ENSMUST00000085435.5
 Csnk1g2
casein kinase 1, gamma 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.5 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.5 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta