Motif ID: Zkscan3

Z-value: 0.286


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_214027550.086.2e-01Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Showing 1 to 20 of 71 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_100786402 0.711 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr11_-_75422586 0.416 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr2_+_104095796 0.357 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr3_+_146500071 0.339 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr4_+_156026120 0.323 ENSMUST00000103173.3
Tnfrsf18
tumor necrosis factor receptor superfamily, member 18
chr3_+_79629074 0.307 ENSMUST00000029388.8
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr5_-_88675613 0.284 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr3_+_146499850 0.256 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr10_-_33951190 0.216 ENSMUST00000048222.4
Zufsp
zinc finger with UFM1-specific peptidase domain
chrX_-_17571563 0.215 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chrX_-_17572241 0.188 ENSMUST00000176638.1
ENSMUST00000026016.6
Fundc1

FUN14 domain containing 1

chr5_+_24985840 0.179 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr11_-_75422524 0.178 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr5_-_88675190 0.174 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr8_+_33732237 0.170 ENSMUST00000171010.1
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr14_+_51893610 0.169 ENSMUST00000047726.5
ENSMUST00000161888.1
Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr13_-_19395728 0.167 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr1_+_132298606 0.156 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr2_+_104069819 0.156 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr12_+_76533540 0.154 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.5 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.5 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular_function category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta