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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for AACACUG
Z-value: 0.68
Motif logo
miRNA associated with seed AACACUG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-141-3p
|
MIMAT0000432 |
|
hsa-miR-200a-3p
|
MIMAT0000682 |
Activity profile of AACACUG motif
Sorted Z-values of AACACUG motif
Network of associatons between targets according to the STRING database.
First level regulatory network of AACACUG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 7.1 | GO:0021592 | fourth ventricle development(GO:0021592) third ventricle development(GO:0021678) |
| 1.7 | 6.8 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 1.4 | 4.2 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 1.2 | 3.6 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 1.1 | 5.7 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 1.0 | 11.6 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.9 | 5.6 | GO:0061687 | detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) |
| 0.7 | 2.1 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 0.7 | 2.8 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.7 | 2.1 | GO:0010040 | response to iron(II) ion(GO:0010040) |
| 0.7 | 2.0 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.7 | 2.6 | GO:1903294 | regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
| 0.6 | 3.2 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.6 | 1.9 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.6 | 2.4 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.6 | 1.8 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.6 | 4.2 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.6 | 3.4 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.5 | 2.1 | GO:1990834 | response to odorant(GO:1990834) |
| 0.5 | 1.4 | GO:0060775 | cardiac right atrium morphogenesis(GO:0003213) mediolateral intercalation(GO:0060031) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) regulation of cell proliferation in midbrain(GO:1904933) |
| 0.5 | 6.9 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.5 | 3.2 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.5 | 2.3 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 0.5 | 2.3 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.4 | 2.2 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.4 | 5.2 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.4 | 1.3 | GO:0042704 | uterine wall breakdown(GO:0042704) |
| 0.4 | 1.6 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 0.4 | 1.2 | GO:0060382 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
| 0.4 | 1.1 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.4 | 2.1 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.3 | 2.6 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.3 | 2.3 | GO:0060701 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
| 0.3 | 1.6 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.3 | 0.9 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.3 | 0.9 | GO:1901491 | axial mesoderm morphogenesis(GO:0048319) negative regulation of lymphangiogenesis(GO:1901491) |
| 0.3 | 2.0 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.3 | 2.5 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.3 | 1.7 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.3 | 2.5 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.3 | 5.9 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.3 | 3.3 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.2 | 6.0 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.2 | 7.6 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.2 | 2.7 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.2 | 0.7 | GO:0032328 | alanine transport(GO:0032328) |
| 0.2 | 2.7 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.2 | 1.3 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 0.9 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.2 | 1.8 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.2 | 2.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.2 | 1.3 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.2 | 2.0 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.2 | 3.1 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.2 | 0.6 | GO:1905053 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.2 | 0.9 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.2 | 0.5 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.2 | 0.7 | GO:2000426 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.2 | 0.7 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.2 | 1.5 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.2 | 1.3 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.2 | 1.3 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 0.2 | 1.7 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.2 | 0.5 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
| 0.2 | 1.0 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.2 | 1.0 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.2 | 1.3 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.2 | 1.9 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.2 | 1.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.2 | 1.1 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.2 | 1.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.2 | 1.4 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.1 | 1.2 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 2.0 | GO:0046007 | negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 9.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 1.4 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 0.4 | GO:0015783 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.1 | 0.8 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.1 | 4.1 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.1 | 0.7 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 1.5 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.1 | 0.9 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.1 | 0.6 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.1 | 1.3 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.1 | 0.4 | GO:0030821 | negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) |
| 0.1 | 0.6 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.1 | 1.1 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 2.7 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 1.0 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.1 | 0.5 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.1 | 1.2 | GO:0007512 | adult heart development(GO:0007512) |
| 0.1 | 0.4 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.1 | 1.1 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.1 | 0.9 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.5 | GO:0010748 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.1 | 0.3 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
| 0.1 | 4.5 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.1 | 3.4 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 1.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.1 | 2.4 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.1 | 0.2 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.1 | 1.8 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.6 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 3.8 | GO:0043486 | histone exchange(GO:0043486) |
| 0.1 | 1.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 0.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 1.3 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.1 | 0.3 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.1 | 1.3 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 1.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 1.4 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 1.1 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.1 | 0.7 | GO:0030223 | neutrophil differentiation(GO:0030223) |
| 0.1 | 1.1 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 1.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.2 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 0.4 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.1 | 0.6 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.1 | 2.2 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.1 | 1.6 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.1 | 3.3 | GO:0090102 | cochlea development(GO:0090102) |
| 0.1 | 0.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 1.0 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 0.9 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.1 | 1.6 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.1 | 0.5 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 0.5 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 1.0 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 1.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 0.8 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.9 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 0.4 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.0 | 0.8 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.3 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.0 | 3.7 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.0 | 0.5 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.0 | 0.2 | GO:0051029 | rRNA transport(GO:0051029) |
| 0.0 | 0.4 | GO:0089700 | protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727) |
| 0.0 | 0.2 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.0 | 1.8 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.2 | GO:1901091 | regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094) |
| 0.0 | 1.0 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.0 | 0.2 | GO:0021764 | amygdala development(GO:0021764) |
| 0.0 | 0.1 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.0 | 0.3 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.1 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 0.0 | 1.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 2.3 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.9 | GO:0007129 | synapsis(GO:0007129) |
| 0.0 | 1.4 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 1.8 | GO:0001756 | somitogenesis(GO:0001756) |
| 0.0 | 0.4 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.0 | 2.9 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 1.7 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.8 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.2 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.0 | 0.7 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.0 | 0.4 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.8 | GO:0016577 | histone demethylation(GO:0016577) |
| 0.0 | 0.7 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.0 | 0.5 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
| 0.0 | 1.3 | GO:0021766 | hippocampus development(GO:0021766) |
| 0.0 | 0.1 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.0 | 0.4 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 1.5 | GO:0048675 | axon extension(GO:0048675) |
| 0.0 | 0.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 2.1 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.0 | 6.1 | GO:0000226 | microtubule cytoskeleton organization(GO:0000226) |
| 0.0 | 0.0 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.0 | 1.3 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.5 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 7.4 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.8 | 2.5 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.8 | 3.2 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.7 | 2.9 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.7 | 7.6 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.6 | 1.8 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.5 | 2.2 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.5 | 2.6 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.4 | 1.3 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.4 | 2.3 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.4 | 4.1 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.4 | 2.5 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.3 | 1.7 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.3 | 1.7 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.3 | 0.9 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.3 | 5.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 1.0 | GO:0071942 | XPC complex(GO:0071942) |
| 0.2 | 9.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 6.6 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 0.8 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.2 | 3.8 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 2.0 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.2 | 0.6 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.2 | 1.8 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.2 | 6.3 | GO:1990752 | microtubule end(GO:1990752) |
| 0.2 | 1.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 2.6 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.7 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.1 | 5.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 2.2 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 5.7 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 1.5 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 1.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 1.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 2.0 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 2.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 1.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 0.8 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.1 | 1.2 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.1 | 0.6 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.1 | 2.2 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 2.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 1.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 5.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 3.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 0.4 | GO:0005879 | axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279) |
| 0.1 | 6.3 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 8.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 0.2 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 10.4 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.4 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.5 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 4.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 1.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 4.4 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 1.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 5.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.5 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.0 | 0.8 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 4.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.9 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 3.4 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 1.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 4.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 3.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 11.6 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 0.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 4.4 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.3 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 3.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 2.1 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 4.4 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.3 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.1 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.2 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 3.6 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 6.6 | GO:0045121 | membrane raft(GO:0045121) |
| 0.0 | 0.4 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 1.8 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 1.0 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.8 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 1.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 1.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.1 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 1.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.1 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.0 | 0.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.4 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 2.6 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 1.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.7 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 1.0 | 4.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.8 | 6.8 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.7 | 2.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 0.7 | 2.0 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.6 | 1.7 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.6 | 1.7 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.5 | 2.9 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.5 | 1.8 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.4 | 5.2 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.4 | 1.1 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.4 | 1.1 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.4 | 1.5 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.3 | 6.5 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.3 | 1.0 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.3 | 2.3 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.3 | 7.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.3 | 5.6 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.3 | 7.6 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.3 | 1.4 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.3 | 2.3 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.3 | 2.5 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.3 | 2.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.3 | 1.3 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.2 | 1.0 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 2.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.2 | 1.5 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 1.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.2 | 3.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 1.2 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.2 | 1.2 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.2 | 0.7 | GO:0004513 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 0.2 | 8.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 2.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.2 | 6.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 6.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 1.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.2 | 2.0 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.2 | 2.2 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 3.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 1.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 4.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.6 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 0.1 | 0.5 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.1 | 0.4 | GO:0005457 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.1 | 6.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 3.7 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 3.9 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.3 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 9.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.1 | 0.4 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.1 | 2.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 0.9 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 2.0 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 1.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 0.9 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.7 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.1 | 2.3 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.6 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 0.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 3.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.4 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 2.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 0.4 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.1 | 1.6 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.1 | 1.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 3.8 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.1 | 1.1 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.1 | 0.6 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.1 | 4.5 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
| 0.1 | 1.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 1.8 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 2.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.3 | GO:0043546 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) molybdopterin cofactor binding(GO:0043546) |
| 0.1 | 1.4 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 1.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 1.3 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 2.1 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 2.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 1.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.4 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 2.1 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 1.0 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.3 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.0 | 2.8 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.2 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.0 | 0.2 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 0.5 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.5 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.0 | 1.2 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 1.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.4 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.0 | 1.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.2 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.0 | 2.2 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.4 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 2.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 2.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.4 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.1 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.0 | 2.6 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 2.2 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.3 | GO:0015172 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.0 | 0.1 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.0 | 0.5 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 2.5 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.0 | 1.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.5 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.2 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 4.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 3.8 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 2.9 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 6.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 2.0 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 2.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 1.3 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 4.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 2.9 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 2.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 2.0 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 2.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 2.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 2.5 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 0.9 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 2.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.7 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 1.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.8 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.6 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.8 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 8.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.3 | 5.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.3 | 6.0 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.3 | 7.6 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.3 | 6.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.2 | 2.6 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.2 | 7.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 5.4 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 3.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.2 | 3.1 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.2 | 1.2 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.1 | 2.6 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 2.3 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 4.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 1.6 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.1 | 1.6 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 2.3 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 1.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 1.3 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 4.2 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 2.1 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.2 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 1.9 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.3 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 2.7 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.8 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 1.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 2.2 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 2.3 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 2.1 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.7 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 1.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.4 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 1.9 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 2.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.9 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.9 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 1.9 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 3.9 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 1.0 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.5 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 3.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.9 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.4 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 1.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 1.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 4.0 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.5 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 1.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.3 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 0.0 | 1.7 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 3.4 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.4 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 1.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 1.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.2 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 1.2 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |