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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AACGGAA

Z-value: 0.09

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miRNA associated with seed AACGGAA

NamemiRBASE accession
hsa-miR-191-5p
MIMAT0000440

Activity profile of AACGGAA motif

Sorted Z-values of AACGGAA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AACGGAA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_115623502 0.63 ENST00000305124.11
ENST00000393780.3
GAP43
growth associated protein 43
chr10_-_79445617 0.48 ENST00000372336.4
ZCCHC24
zinc finger CCHC-type containing 24
chr7_-_108456378 0.44 ENST00000613830.4
ENST00000413765.6
ENST00000379028.8
NRCAM
neuronal cell adhesion molecule
chr17_-_48545077 0.28 ENST00000330070.6
HOXB2
homeobox B2
chr10_+_117542416 0.21 ENST00000442245.5
EMX2
empty spiracles homeobox 2
chr7_-_72336995 0.21 ENST00000329008.9
CALN1
calneuron 1
chr8_-_133102477 0.20 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
SLA
Src like adaptor
chr1_+_4654601 0.16 ENST00000378191.5
AJAP1
adherens junctions associated protein 1
chr6_+_116280098 0.14 ENST00000643175.1
ENST00000452085.7
DSE
dermatan sulfate epimerase
chr9_+_130579556 0.13 ENST00000319725.10
FUBP3
far upstream element binding protein 3
chr3_-_18425295 0.10 ENST00000338745.11
ENST00000450898.1
SATB1
SATB homeobox 1
chr18_+_34978244 0.10 ENST00000436190.6
MAPRE2
microtubule associated protein RP/EB family member 2
chr2_-_207769889 0.09 ENST00000295417.4
FZD5
frizzled class receptor 5
chr5_+_150508110 0.07 ENST00000261797.7
NDST1
N-deacetylase and N-sulfotransferase 1
chr2_+_26970628 0.07 ENST00000233121.7
ENST00000405074.7
MAPRE3
microtubule associated protein RP/EB family member 3
chr7_-_92833896 0.07 ENST00000265734.8
CDK6
cyclin dependent kinase 6
chr16_-_4847265 0.06 ENST00000591451.5
ENST00000436648.9
ENST00000321919.14
ENST00000588297.5
GLYR1
glyoxylate reductase 1 homolog
chr12_-_116881431 0.05 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein
chr3_-_52056552 0.02 ENST00000495880.2
DUSP7
dual specificity phosphatase 7
chrX_-_41922992 0.01 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
CASK
calcium/calmodulin dependent serine protein kinase
chr9_-_16870662 0.01 ENST00000380672.9
BNC2
basonuclin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins