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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for AAUCUCU
Z-value: 0.17
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miRNA associated with seed AAUCUCU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-216b-5p
|
MIMAT0004959 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AAUCUCU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.9 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.2 | 2.2 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 1.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 1.5 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.4 | 1.1 | GO:1902822 | positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336) |
| 0.0 | 0.8 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.0 | 0.7 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.6 | GO:1901475 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 0.6 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.1 | 0.4 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 1.9 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.3 | 1.8 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 1.5 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.4 | 1.1 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.9 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.0 | 2.2 | GO:0008235 | aminopeptidase activity(GO:0004177) metalloexopeptidase activity(GO:0008235) |
| 0.1 | 1.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 1.1 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.2 | 0.6 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.0 | 0.3 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 0.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.0 | 0.0 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |