ISMARA results: ACCCGUA

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ACCCGUA

Z-value: 0.07

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miRNA associated with seed ACCCGUA

Name	miRBASE accession
hsa-miR-100-5p miRBase	MIMAT0000098
hsa-miR-99a-5p miRBase	MIMAT0000097
hsa-miR-99b-5p miRBase	MIMAT0000689

Activity profile of ACCCGUA motif

Sorted Z-values of ACCCGUA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACCCGUA

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Promoter	Score	Transcript	Gene	Gene Info
chr3_+_152299392 Show fit	0.44	ENST00000498502.5 ENST00000545754.5 ENST00000357472.7 ENST00000324196.9	MBNL1 Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 1
chr8_-_140635617 Show fit	0.38	ENST00000220592.10	AGO2 Ensembl NCBI GeneCards UniProt Show fit	argonaute RISC catalytic component 2
chr2_+_12716893 Show fit	0.21	ENST00000381465.2 ENST00000155926.9	TRIB2 Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 2
chr8_+_125430333 Show fit	0.19	ENST00000311922.4	TRIB1 Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 1
chr11_+_87037820 Show fit	0.16	ENST00000340353.11	TMEM135 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 135
chr4_+_143513661 Show fit	0.15	ENST00000283131.4	SMARCA5 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr6_-_75284736 Show fit	0.14	ENST00000674038.1 ENST00000673730.1 ENST00000230461.11	TMEM30A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 30A
chr6_-_89412219 Show fit	0.10	ENST00000369415.9	RRAGD Ensembl NCBI GeneCards UniProt Show fit	Ras related GTP binding D
chr7_-_27095972 Show fit	0.09	ENST00000355633.5 ENST00000643460.2	HOXA1 Ensembl NCBI GeneCards UniProt Show fit	homeobox A1
chr22_+_29883158 Show fit	0.08	ENST00000333027.7 ENST00000401950.7 ENST00000445401.5 ENST00000323630.9 ENST00000351488.7	MTMR3 Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 3

Showing 1 to 10 of 19 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.2	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1	0.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0071233	cellular response to leucine(GO:0071233)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)

Showing 1 to 6 of 6 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.4	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	GO:0016589	NURF complex(GO:0016589)
0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	GO:0034657	GID complex(GO:0034657)

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.4	GO:0098808	mRNA cap binding(GO:0098808)
0.0	0.4	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)

Showing 1 to 4 of 4 entries

Results for ACCCGUA

Z-value: 0.07

Motif logo

miRNA associated with seed ACCCGUA

Activity profile of ACCCGUA motif

Sorted Z-values of ACCCGUA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACCCGUA

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: