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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ATF4

Z-value: 1.13

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Transcription factors associated with ATF4

Gene Symbol Gene ID Gene Info
ATF4
ENSG00000128272.17 ATF4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF4hg38_v1_chr22_+_39520553_395206040.601.1e-22Click!

Activity profile of ATF4 motif

Sorted Z-values of ATF4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_57230301 29.35 ENST00000553474.5
SHMT2
serine hydroxymethyltransferase 2
chr12_+_57230336 27.29 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
SHMT2
serine hydroxymethyltransferase 2
chr7_+_30594823 25.65 ENST00000675810.1
ENST00000674815.1
ENST00000454308.6
ENST00000389266.8
ENST00000675693.1
ENST00000675651.1
ENST00000674851.1
GARS1
glycyl-tRNA synthetase 1
chr5_+_33440947 25.08 ENST00000455217.6
ENST00000265112.8
TARS1
threonyl-tRNA synthetase 1
chr5_+_33440696 24.18 ENST00000502553.5
ENST00000514259.5
TARS1
threonyl-tRNA synthetase 1
chr9_-_92293674 22.27 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
IARS1
isoleucyl-tRNA synthetase 1
chr12_+_57230086 21.87 ENST00000414700.7
ENST00000557703.5
SHMT2
serine hydroxymethyltransferase 2
chr12_-_46268989 21.74 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
SLC38A1
solute carrier family 38 member 1
chr17_-_81937221 20.63 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
PYCR1
pyrroline-5-carboxylate reductase 1
chr14_-_100375333 19.98 ENST00000557297.5
ENST00000555813.5
ENST00000392882.7
ENST00000557135.5
ENST00000556698.5
ENST00000554509.5
ENST00000555410.5
WARS1
tryptophanyl-tRNA synthetase 1
chr19_-_46784733 19.68 ENST00000593713.1
ENST00000598022.1
ENST00000434726.6
SLC1A5
solute carrier family 1 member 5
chr17_-_81937277 19.61 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
PYCR1
pyrroline-5-carboxylate reductase 1
chr17_-_81937320 18.65 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
PYCR1
pyrroline-5-carboxylate reductase 1
chr19_-_46784905 17.68 ENST00000594991.5
SLC1A5
solute carrier family 1 member 5
chr14_-_100375602 16.85 ENST00000553395.5
ENST00000553545.5
ENST00000344102.9
ENST00000556338.5
ENST00000553934.1
WARS1
tryptophanyl-tRNA synthetase 1
chr1_-_32817311 16.76 ENST00000373477.9
ENST00000675785.1
YARS1
tyrosyl-tRNA synthetase 1
chrX_+_24054931 15.74 ENST00000253039.9
ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2 subunit gamma
chr5_+_179678613 15.63 ENST00000681674.1
ENST00000681712.1
ENST00000681903.1
CANX
calnexin
chr7_+_99408958 14.99 ENST00000222969.10
BUD31
BUD31 homolog
chr5_+_44808930 14.54 ENST00000507110.6
MRPS30
mitochondrial ribosomal protein S30
chr7_+_99408609 13.71 ENST00000403633.6
BUD31
BUD31 homolog
chr12_+_57229694 13.71 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
SHMT2
serine hydroxymethyltransferase 2
chr10_+_100347225 13.43 ENST00000370355.3
SCD
stearoyl-CoA desaturase
chr9_+_78297143 13.04 ENST00000347159.6
PSAT1
phosphoserine aminotransferase 1
chr9_+_78297117 12.85 ENST00000376588.4
PSAT1
phosphoserine aminotransferase 1
chr19_+_33374312 12.29 ENST00000585933.2
CEBPG
CCAAT enhancer binding protein gamma
chr16_-_70289480 11.58 ENST00000261772.13
ENST00000675953.1
ENST00000675691.1
ENST00000675133.1
ENST00000674512.1
ENST00000675045.1
ENST00000675853.1
ENST00000565361.3
ENST00000674963.1
ENST00000674691.1
AARS1
alanyl-tRNA synthetase 1
chr11_-_3057386 11.56 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
CARS1
cysteinyl-tRNA synthetase 1
chr14_+_24094053 11.09 ENST00000559250.5
ENST00000560736.5
ENST00000396973.8
ENST00000559837.5
PCK2
phosphoenolpyruvate carboxykinase 2, mitochondrial
chr1_-_220046432 10.35 ENST00000609181.5
ENST00000366923.8
EPRS1
glutamyl-prolyl-tRNA synthetase 1
chr7_-_56034133 10.15 ENST00000421626.5
PSPH
phosphoserine phosphatase
chr21_-_43075831 9.90 ENST00000398158.5
ENST00000398165.8
CBS
cystathionine beta-synthase
chr10_+_14838288 9.63 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
ENSG00000284024.4
HSPA14
novel protein
heat shock protein family A (Hsp70) member 14
chr14_+_24094301 9.40 ENST00000545054.6
ENST00000561286.5
ENST00000216780.9
ENST00000558096.5
PCK2
phosphoenolpyruvate carboxykinase 2, mitochondrial
chr11_+_62881686 9.20 ENST00000536981.6
ENST00000539891.6
SLC3A2
solute carrier family 3 member 2
chr12_+_57455266 9.06 ENST00000266646.3
INHBE
inhibin subunit beta E
chr19_+_33373694 8.55 ENST00000284000.9
CEBPG
CCAAT enhancer binding protein gamma
chr9_+_97983332 7.96 ENST00000339399.5
ANP32B
acidic nuclear phosphoprotein 32 family member B
chr17_-_79839387 7.69 ENST00000448310.1
ENST00000269397.9
CBX4
chromobox 4
chr10_-_95656643 7.50 ENST00000371221.3
ENST00000371224.7
ALDH18A1
aldehyde dehydrogenase 18 family member A1
chr21_-_6467509 7.47 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
CBSL
cystathionine beta-synthase like
chr1_+_154272589 7.14 ENST00000457918.6
ENST00000483970.6
ENST00000328703.12
ENST00000435087.1
ENST00000532105.1
HAX1
HCLS1 associated protein X-1
chr15_+_40953463 6.28 ENST00000617768.5
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr11_+_119085200 5.39 ENST00000650101.1
HMBS
hydroxymethylbilane synthase
chr10_-_99430617 5.29 ENST00000370508.7
GOT1
glutamic-oxaloacetic transaminase 1
chr12_+_49741802 5.18 ENST00000423828.5
ENST00000550445.5
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr17_+_41689862 4.96 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr12_-_24949026 4.63 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
BCAT1
branched chain amino acid transaminase 1
chr11_+_119084873 4.45 ENST00000652429.1
ENST00000442944.7
ENST00000537841.5
ENST00000542729.5
ENST00000546302.6
ENST00000536813.6
ENST00000544387.5
ENST00000543090.5
HMBS
hydroxymethylbilane synthase
chr18_-_57621741 4.02 ENST00000587194.1
ENST00000591599.5
ENST00000588661.5
ENST00000256854.10
NARS1
asparaginyl-tRNA synthetase 1
chrX_-_134658450 3.72 ENST00000359237.9
PLAC1
placenta enriched 1
chrX_-_81201886 3.42 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
HMGN5
high mobility group nucleosome binding domain 5
chr5_+_174724549 3.06 ENST00000239243.7
ENST00000507785.2
MSX2
msh homeobox 2
chr7_-_99408548 3.05 ENST00000626285.1
ENST00000350498.8
PDAP1
PDGFA associated protein 1
chr17_-_48626325 3.02 ENST00000311177.7
HOXB9
homeobox B9
chr22_+_41833079 2.89 ENST00000612482.4
ENST00000361204.9
SREBF2
sterol regulatory element binding transcription factor 2
chr17_+_75093287 2.84 ENST00000538213.6
ENST00000584118.1
SLC16A5
solute carrier family 16 member 5
chr5_+_154755272 2.75 ENST00000518297.6
LARP1
La ribonucleoprotein 1, translational regulator
chr1_-_44031446 2.74 ENST00000372310.8
ENST00000466926.1
SLC6A9
solute carrier family 6 member 9
chr2_-_177264686 2.71 ENST00000397062.8
ENST00000430047.1
NFE2L2
nuclear factor, erythroid 2 like 2
chr14_-_91946989 2.33 ENST00000556154.5
FBLN5
fibulin 5
chr16_+_56936654 2.27 ENST00000563911.5
HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1
chr1_-_44031352 1.39 ENST00000372306.7
ENST00000475075.6
SLC6A9
solute carrier family 6 member 9
chr14_+_60981114 1.24 ENST00000354886.6
SLC38A6
solute carrier family 38 member 6
chr5_-_146182475 1.08 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
LARS1
leucyl-tRNA synthetase 1
chr11_+_22666604 1.06 ENST00000454584.6
GAS2
growth arrest specific 2
chr12_-_116881062 0.84 ENST00000550505.5
HRK
harakiri, BCL2 interacting protein
chr16_-_67660694 0.80 ENST00000219251.13
ENST00000620338.4
ACD
ACD shelterin complex subunit and telomerase recruitment factor
chr2_-_55334529 0.80 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
CCDC88A
coiled-coil domain containing 88A
chr9_+_36169382 0.71 ENST00000335119.4
CCIN
calicin
chr8_-_38150943 0.62 ENST00000276449.9
STAR
steroidogenic acute regulatory protein
chr2_-_215436061 0.58 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
FN1
fibronectin 1
chr5_-_146182591 0.39 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
LARS1
leucyl-tRNA synthetase 1
chr12_-_49904217 0.31 ENST00000550635.6
FAIM2
Fas apoptotic inhibitory molecule 2
chr3_-_3109980 0.18 ENST00000256452.7
ENST00000311981.12
ENST00000430514.6
ENST00000456302.5
IL5RA
interleukin 5 receptor subunit alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
15.4 92.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
9.3 37.4 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
8.6 25.9 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
8.3 66.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
3.6 28.7 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
3.5 17.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
3.3 9.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
2.1 20.8 GO:0045078 enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
2.0 20.5 GO:0006116 NADH oxidation(GO:0006116)
1.8 5.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
1.5 9.2 GO:0060356 leucine import(GO:0060356)
1.4 10.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.4 4.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.9 4.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.9 2.8 GO:1901355 response to rapamycin(GO:1901355)
0.9 5.2 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.8 15.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 3.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.7 2.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.7 21.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.7 2.7 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.5 5.0 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.4 6.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 7.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 3.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.2 8.0 GO:0021591 ventricular system development(GO:0021591) positive regulation of protein export from nucleus(GO:0046827)
0.2 13.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2 0.6 GO:0071373 phthalate metabolic process(GO:0018963) cellular response to luteinizing hormone stimulus(GO:0071373)
0.2 0.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 14.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 9.6 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 9.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 3.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 7.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 3.0 GO:0048706 embryonic skeletal system development(GO:0048706)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 92.2 GO:0070552 BRISC complex(GO:0070552)
3.9 15.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.0 15.6 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.7 2.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.5 7.7 GO:0035102 PRC1 complex(GO:0035102)
0.3 2.8 GO:0031931 TORC1 complex(GO:0031931)
0.2 0.7 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.2 36.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.4 GO:0071953 elastic fiber(GO:0071953)
0.1 79.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 28.7 GO:0005681 spliceosomal complex(GO:0005681)
0.1 7.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 24.2 GO:0005840 ribosome(GO:0005840)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 5.3 GO:0043679 axon terminus(GO:0043679)
0.0 7.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 6.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 5.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 2.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 6.1 GO:0000785 chromatin(GO:0000785)
0.0 33.5 GO:0070062 extracellular exosome(GO:0070062)
0.0 9.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
15.4 92.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
9.8 58.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
6.8 20.5 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
4.7 37.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
3.5 17.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
3.4 13.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
3.3 9.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
2.5 10.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.9 7.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.8 5.3 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.3 30.5 GO:0008483 transaminase activity(GO:0008483)
1.0 4.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
1.0 30.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
1.0 2.9 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.7 5.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.6 20.8 GO:0008301 DNA binding, bending(GO:0008301)
0.6 15.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.6 6.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.4 7.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 7.7 GO:0032183 SUMO binding(GO:0032183)
0.3 24.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3 20.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.8 GO:0000339 RNA cap binding(GO:0000339)
0.1 9.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 8.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 14.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 2.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 20.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 7.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 4.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 107.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.4 68.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
1.0 15.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.8 9.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 9.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 20.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 7.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 4.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 15.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 4.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones