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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for BARHL1
Z-value: 2.07
Motif logo
Transcription factors associated with BARHL1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
BARHL1
|
ENSG00000125492.10 | BARHL1 |
Activity profile of BARHL1 motif
Sorted Z-values of BARHL1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of BARHL1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 19.6 | 58.9 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 18.6 | 74.5 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 16.6 | 66.4 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 16.0 | 64.2 | GO:0019860 | uracil metabolic process(GO:0019860) |
| 14.6 | 58.3 | GO:0002188 | translation reinitiation(GO:0002188) |
| 14.2 | 42.7 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 11.7 | 46.9 | GO:0070981 | L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982) |
| 11.2 | 44.7 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 9.9 | 49.6 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 9.6 | 28.8 | GO:0071283 | cellular response to iron(III) ion(GO:0071283) |
| 9.5 | 66.7 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 9.3 | 37.1 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 9.3 | 27.8 | GO:1900195 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
| 9.2 | 46.1 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 8.8 | 26.3 | GO:0034476 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 8.2 | 48.9 | GO:0008204 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 8.0 | 8.0 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 7.8 | 46.7 | GO:0051177 | meiotic sister chromatid cohesion(GO:0051177) |
| 7.5 | 22.6 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 7.5 | 44.8 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 7.4 | 44.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 7.3 | 21.9 | GO:1904908 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 7.0 | 20.9 | GO:0071373 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 6.7 | 20.0 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 6.6 | 26.3 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 6.5 | 26.0 | GO:0072186 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 6.4 | 19.2 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 6.4 | 25.4 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 6.3 | 19.0 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 6.3 | 31.3 | GO:0097240 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 6.2 | 18.6 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 6.2 | 43.3 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
| 6.2 | 37.0 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 6.1 | 30.4 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 6.0 | 42.0 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 5.9 | 76.7 | GO:0006265 | DNA topological change(GO:0006265) |
| 5.9 | 11.8 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 5.8 | 23.4 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 5.8 | 17.4 | GO:0070476 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 5.7 | 28.3 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 5.6 | 22.4 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 5.5 | 16.5 | GO:0015866 | ADP transport(GO:0015866) |
| 5.5 | 71.4 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 5.5 | 21.8 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 5.4 | 16.2 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778) |
| 5.3 | 21.2 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535) |
| 5.3 | 15.9 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 5.1 | 20.4 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 5.0 | 25.0 | GO:0060296 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 5.0 | 15.0 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 5.0 | 29.9 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
| 4.9 | 19.6 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 4.9 | 14.7 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 4.9 | 19.5 | GO:0046502 | uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502) |
| 4.8 | 19.2 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 4.8 | 19.0 | GO:0051311 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 4.7 | 65.7 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 4.6 | 64.4 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 4.6 | 13.7 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 4.6 | 13.7 | GO:1904688 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 4.5 | 9.1 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 4.5 | 31.7 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 4.5 | 13.5 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 4.5 | 9.0 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 4.4 | 137.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 4.4 | 4.4 | GO:0033048 | negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of chromosome segregation(GO:0051985) negative regulation of mitotic sister chromatid separation(GO:2000816) |
| 4.4 | 39.8 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 4.4 | 13.2 | GO:0060382 | regulation of DNA strand elongation(GO:0060382) |
| 4.3 | 13.0 | GO:0033168 | conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404) |
| 4.1 | 8.3 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 4.1 | 12.4 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 4.1 | 37.1 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 4.0 | 8.0 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
| 3.9 | 35.4 | GO:0009249 | protein lipoylation(GO:0009249) |
| 3.9 | 19.5 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
| 3.8 | 11.5 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 3.8 | 7.6 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 3.8 | 37.6 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 3.7 | 11.2 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 3.7 | 11.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 3.7 | 7.4 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 3.7 | 40.5 | GO:0042262 | DNA protection(GO:0042262) |
| 3.6 | 10.9 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 3.6 | 14.5 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 3.6 | 25.1 | GO:1903301 | positive regulation of hexokinase activity(GO:1903301) |
| 3.5 | 10.6 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 3.5 | 45.7 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 3.5 | 10.5 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 3.5 | 27.7 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 3.5 | 13.9 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 3.5 | 10.4 | GO:0072428 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 3.4 | 6.8 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
| 3.4 | 40.6 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 3.4 | 10.1 | GO:2000866 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
| 3.4 | 37.1 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 3.4 | 30.3 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 3.4 | 26.8 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 3.3 | 19.9 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 3.3 | 13.1 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 3.3 | 9.8 | GO:1902594 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 3.2 | 16.2 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 3.2 | 9.7 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 3.2 | 22.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 3.2 | 19.0 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 3.2 | 6.3 | GO:0002424 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) |
| 3.1 | 34.5 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 3.1 | 24.8 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 3.1 | 330.7 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 3.1 | 12.3 | GO:0018032 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 3.1 | 6.1 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 3.0 | 33.5 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 3.0 | 9.1 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 3.0 | 15.0 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 3.0 | 8.9 | GO:1901355 | response to rapamycin(GO:1901355) |
| 3.0 | 5.9 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 3.0 | 20.7 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
| 3.0 | 64.9 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 2.9 | 8.8 | GO:0016107 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224) |
| 2.9 | 17.4 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 2.9 | 8.7 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 2.8 | 48.4 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 2.8 | 59.5 | GO:0008228 | opsonization(GO:0008228) |
| 2.8 | 36.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 2.8 | 38.9 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 2.8 | 11.1 | GO:0072683 | T cell extravasation(GO:0072683) |
| 2.7 | 54.9 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 2.7 | 19.0 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 2.7 | 13.5 | GO:1902896 | terminal web assembly(GO:1902896) |
| 2.7 | 40.3 | GO:0000338 | protein deneddylation(GO:0000338) |
| 2.7 | 18.7 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 2.7 | 34.7 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 2.7 | 21.4 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 2.7 | 16.0 | GO:0015853 | adenine transport(GO:0015853) |
| 2.6 | 23.7 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 2.6 | 13.1 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 2.6 | 20.9 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 2.6 | 15.7 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 2.6 | 23.1 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 2.5 | 7.6 | GO:1903438 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 2.5 | 33.0 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 2.5 | 40.6 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 2.5 | 10.1 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 2.5 | 25.1 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 2.5 | 17.6 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 2.5 | 22.5 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 2.5 | 32.3 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 2.4 | 4.9 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 2.4 | 29.0 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 2.4 | 14.4 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 2.4 | 14.3 | GO:0019255 | UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255) |
| 2.4 | 7.1 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 2.4 | 9.5 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 2.3 | 35.1 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 2.3 | 9.3 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 2.3 | 11.6 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 2.3 | 6.9 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 2.3 | 146.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 2.2 | 8.9 | GO:0007144 | female meiosis I(GO:0007144) |
| 2.2 | 28.8 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 2.2 | 17.6 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 2.2 | 13.2 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 2.2 | 6.5 | GO:0034552 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 2.2 | 8.6 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 2.1 | 16.7 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 2.1 | 156.8 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 2.1 | 98.1 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 2.1 | 6.3 | GO:0051182 | coenzyme transport(GO:0051182) |
| 2.1 | 6.2 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 2.1 | 10.3 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 2.0 | 28.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 2.0 | 15.8 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 2.0 | 7.9 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 2.0 | 3.9 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 2.0 | 29.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 2.0 | 7.9 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 2.0 | 7.9 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 2.0 | 7.9 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 2.0 | 9.8 | GO:1900368 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 1.9 | 7.7 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 1.9 | 17.2 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 1.9 | 13.4 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 1.9 | 30.4 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 1.9 | 11.4 | GO:0042996 | regulation of Golgi to plasma membrane protein transport(GO:0042996) |
| 1.9 | 5.7 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 1.9 | 24.7 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 1.9 | 11.2 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 1.9 | 14.9 | GO:0070900 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 1.8 | 11.0 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 1.8 | 25.7 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 1.8 | 5.5 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619) |
| 1.8 | 7.3 | GO:1904045 | cellular response to aldosterone(GO:1904045) |
| 1.8 | 18.2 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 1.8 | 10.9 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 1.8 | 3.6 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 1.8 | 7.2 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 1.8 | 12.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 1.8 | 17.9 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 1.8 | 33.8 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 1.8 | 5.3 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 1.8 | 5.3 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
| 1.8 | 7.1 | GO:0046223 | mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 1.8 | 28.4 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 1.8 | 5.3 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 1.8 | 14.0 | GO:0051026 | chiasma assembly(GO:0051026) |
| 1.7 | 10.5 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 1.7 | 5.2 | GO:1904387 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 1.7 | 29.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 1.7 | 8.5 | GO:0030242 | pexophagy(GO:0030242) |
| 1.7 | 22.2 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 1.7 | 3.4 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 1.7 | 30.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 1.7 | 11.8 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 1.7 | 58.6 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 1.7 | 1.7 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 1.7 | 6.7 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 1.7 | 25.0 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 1.7 | 19.9 | GO:0051451 | myoblast migration(GO:0051451) |
| 1.7 | 8.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 1.7 | 14.9 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 1.6 | 21.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 1.6 | 14.7 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 1.6 | 14.6 | GO:0042407 | cristae formation(GO:0042407) |
| 1.6 | 27.4 | GO:1903753 | negative regulation of p38MAPK cascade(GO:1903753) |
| 1.6 | 4.8 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 1.6 | 25.2 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 1.6 | 12.5 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 1.5 | 10.5 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 1.5 | 12.0 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 1.5 | 6.0 | GO:0021817 | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) |
| 1.5 | 10.4 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 1.5 | 16.3 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 1.4 | 11.4 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 1.4 | 41.4 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 1.4 | 18.5 | GO:0006983 | ER overload response(GO:0006983) |
| 1.4 | 2.8 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) |
| 1.4 | 4.2 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 1.4 | 12.6 | GO:0043382 | regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) |
| 1.4 | 5.6 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 1.4 | 15.3 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 1.4 | 2.8 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 1.4 | 26.0 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 1.4 | 55.9 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.4 | 21.8 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 1.4 | 8.2 | GO:0097338 | response to clozapine(GO:0097338) |
| 1.4 | 1.4 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 1.3 | 5.3 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 1.3 | 26.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 1.3 | 54.6 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 1.3 | 5.3 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 1.3 | 11.9 | GO:2000582 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 1.3 | 1.3 | GO:0032875 | regulation of DNA endoreduplication(GO:0032875) |
| 1.3 | 6.5 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 1.3 | 7.8 | GO:0046086 | adenosine biosynthetic process(GO:0046086) |
| 1.3 | 5.2 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 1.3 | 59.2 | GO:0007077 | mitotic nuclear envelope disassembly(GO:0007077) |
| 1.3 | 8.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.3 | 2.5 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 1.2 | 3.7 | GO:0007538 | primary sex determination(GO:0007538) |
| 1.2 | 13.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 1.2 | 2.5 | GO:1990169 | detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) stress response to copper ion(GO:1990169) |
| 1.2 | 17.1 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 1.2 | 26.7 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 1.2 | 9.7 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 1.2 | 42.1 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 1.2 | 10.8 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 1.2 | 3.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 1.2 | 5.9 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 1.2 | 9.4 | GO:0051983 | regulation of chromosome segregation(GO:0051983) |
| 1.2 | 1.2 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 1.2 | 4.6 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 1.1 | 4.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 1.1 | 6.8 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 1.1 | 15.9 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 1.1 | 11.3 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
| 1.1 | 13.5 | GO:0071459 | protein localization to chromosome, centromeric region(GO:0071459) |
| 1.1 | 3.4 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 1.1 | 5.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.1 | 5.6 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 1.1 | 3.3 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 1.1 | 4.4 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 1.1 | 5.5 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 1.1 | 10.0 | GO:0000012 | single strand break repair(GO:0000012) |
| 1.1 | 14.3 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 1.1 | 53.7 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
| 1.1 | 8.7 | GO:0055129 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 1.1 | 5.5 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 1.1 | 16.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.1 | 8.6 | GO:0090151 | establishment of protein localization to mitochondrial membrane(GO:0090151) |
| 1.1 | 2.1 | GO:0031393 | negative regulation of prostaglandin biosynthetic process(GO:0031393) |
| 1.1 | 11.7 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 1.1 | 9.6 | GO:2001169 | regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171) |
| 1.1 | 2.1 | GO:0002905 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765) |
| 1.1 | 12.7 | GO:0032610 | interleukin-1 alpha production(GO:0032610) |
| 1.1 | 3.2 | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) |
| 1.1 | 20.0 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 1.1 | 24.2 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 1.1 | 32.6 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 1.0 | 6.3 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 1.0 | 11.3 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 1.0 | 11.3 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.0 | 24.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 1.0 | 5.1 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 1.0 | 8.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 1.0 | 9.1 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 1.0 | 4.1 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 1.0 | 12.1 | GO:1903599 | positive regulation of mitophagy(GO:1903599) |
| 1.0 | 15.2 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 1.0 | 7.0 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 1.0 | 14.8 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 1.0 | 4.9 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 1.0 | 6.9 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 1.0 | 4.9 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 1.0 | 23.5 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 1.0 | 12.7 | GO:0070986 | left/right axis specification(GO:0070986) |
| 1.0 | 63.5 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 1.0 | 15.6 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 1.0 | 2.9 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 1.0 | 14.5 | GO:0019184 | nonribosomal peptide biosynthetic process(GO:0019184) |
| 1.0 | 5.8 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 1.0 | 5.8 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 1.0 | 4.8 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 1.0 | 2.9 | GO:1901253 | regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253) |
| 0.9 | 0.9 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.9 | 7.6 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.9 | 10.3 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.9 | 3.7 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.9 | 1.9 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.9 | 8.4 | GO:0071492 | response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492) |
| 0.9 | 32.2 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.9 | 5.5 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.9 | 3.7 | GO:1990834 | autophagic cell death(GO:0048102) response to odorant(GO:1990834) |
| 0.9 | 6.4 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.9 | 5.4 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.9 | 3.6 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.9 | 7.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.9 | 2.6 | GO:1900125 | regulation of hyaluronan biosynthetic process(GO:1900125) positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.9 | 0.9 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.9 | 3.5 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.9 | 0.9 | GO:0060559 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 0.9 | 4.3 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.8 | 5.0 | GO:0006064 | glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159) |
| 0.8 | 5.0 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.8 | 7.4 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.8 | 9.9 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.8 | 5.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.8 | 4.1 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.8 | 22.0 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.8 | 23.5 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.8 | 3.2 | GO:0007007 | inner mitochondrial membrane organization(GO:0007007) |
| 0.8 | 4.8 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.8 | 23.1 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.8 | 3.2 | GO:0031125 | rRNA 3'-end processing(GO:0031125) U4 snRNA 3'-end processing(GO:0034475) |
| 0.8 | 24.5 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.8 | 7.8 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.8 | 23.4 | GO:0006625 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.8 | 28.8 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.8 | 3.9 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.8 | 1.5 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.8 | 8.3 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.8 | 14.3 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.7 | 6.0 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.7 | 3.0 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.7 | 3.0 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.7 | 3.7 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.7 | 50.4 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.7 | 10.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.7 | 5.0 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.7 | 21.4 | GO:0043489 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
| 0.7 | 9.3 | GO:0099515 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
| 0.7 | 2.1 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.7 | 3.5 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.7 | 23.2 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.7 | 1.4 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.7 | 2.1 | GO:0010710 | regulation of collagen catabolic process(GO:0010710) |
| 0.7 | 3.5 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.7 | 4.1 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.7 | 7.5 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.7 | 64.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.7 | 3.3 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
| 0.7 | 4.7 | GO:1905066 | arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.7 | 41.3 | GO:0048207 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.7 | 5.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.7 | 7.9 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.7 | 8.6 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.6 | 6.5 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.6 | 5.8 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.6 | 3.8 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.6 | 1.9 | GO:0033210 | leptin-mediated signaling pathway(GO:0033210) |
| 0.6 | 20.1 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.6 | 1.9 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 0.6 | 14.9 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.6 | 15.5 | GO:0006623 | protein targeting to vacuole(GO:0006623) |
| 0.6 | 3.0 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.6 | 3.0 | GO:0033216 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.6 | 6.1 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.6 | 7.3 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.6 | 4.2 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.6 | 9.0 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.6 | 7.8 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.6 | 1.2 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.6 | 4.8 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.6 | 2.9 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.6 | 4.1 | GO:2000002 | negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.6 | 1.8 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.6 | 1.7 | GO:1901475 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.6 | 1.2 | GO:0043323 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.6 | 2.3 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
| 0.6 | 8.6 | GO:0040023 | establishment of nucleus localization(GO:0040023) |
| 0.6 | 4.6 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.6 | 2.3 | GO:0065001 | negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572) specification of axis polarity(GO:0065001) |
| 0.6 | 1.7 | GO:0036233 | glycine import(GO:0036233) |
| 0.6 | 5.1 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.6 | 6.6 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.5 | 2.7 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.5 | 12.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.5 | 5.9 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
| 0.5 | 20.4 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.5 | 12.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.5 | 17.0 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.5 | 2.1 | GO:1904293 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) negative regulation of ERAD pathway(GO:1904293) |
| 0.5 | 4.2 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.5 | 2.6 | GO:0007497 | posterior midgut development(GO:0007497) enteric smooth muscle cell differentiation(GO:0035645) |
| 0.5 | 1.5 | GO:2000302 | positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle exocytosis(GO:2000302) |
| 0.5 | 8.1 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.5 | 12.6 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.5 | 3.9 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.5 | 4.8 | GO:2000059 | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059) |
| 0.5 | 1.9 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 0.5 | 3.3 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 0.5 | 9.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.5 | 4.6 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.5 | 3.2 | GO:0060242 | contact inhibition(GO:0060242) |
| 0.5 | 8.2 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.5 | 16.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.5 | 3.2 | GO:0042226 | interleukin-6 biosynthetic process(GO:0042226) |
| 0.5 | 5.0 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.5 | 28.5 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.4 | 5.8 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.4 | 2.2 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.4 | 2.2 | GO:0045938 | positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
| 0.4 | 3.1 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.4 | 5.7 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.4 | 8.6 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.4 | 3.0 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.4 | 2.5 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.4 | 1.3 | GO:1903069 | regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.4 | 4.6 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.4 | 7.5 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.4 | 10.2 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
| 0.4 | 3.2 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.4 | 24.5 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.4 | 96.3 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.4 | 1.6 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.4 | 1.2 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.4 | 1.2 | GO:2000697 | negative regulation by virus of viral protein levels in host cell(GO:0046725) kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697) |
| 0.4 | 2.3 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.4 | 15.8 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.4 | 0.8 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 0.4 | 0.4 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 0.4 | 0.7 | GO:0006598 | polyamine catabolic process(GO:0006598) spermidine catabolic process(GO:0046203) |
| 0.4 | 1.9 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
| 0.4 | 11.9 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.4 | 3.3 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.4 | 4.1 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.4 | 1.8 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.4 | 1.8 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.4 | 4.3 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.4 | 2.2 | GO:0043247 | telomere maintenance in response to DNA damage(GO:0043247) |
| 0.4 | 1.1 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.4 | 0.7 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.4 | 4.6 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.4 | 1.1 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.4 | 2.5 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.4 | 1.8 | GO:0006551 | leucine metabolic process(GO:0006551) |
| 0.3 | 31.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.3 | 2.7 | GO:0071888 | macrophage apoptotic process(GO:0071888) |
| 0.3 | 6.0 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.3 | 5.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.3 | 2.6 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.3 | 2.6 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.3 | 12.1 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.3 | 8.3 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.3 | 2.5 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.3 | 1.6 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.3 | 16.0 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.3 | 1.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.3 | 3.4 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.3 | 1.5 | GO:0097052 | L-kynurenine metabolic process(GO:0097052) |
| 0.3 | 5.2 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.3 | 7.5 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.3 | 3.3 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.3 | 27.1 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.3 | 11.3 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.3 | 1.9 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.3 | 13.2 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.3 | 3.5 | GO:0001553 | luteinization(GO:0001553) |
| 0.3 | 2.9 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.3 | 2.9 | GO:1902186 | regulation of viral release from host cell(GO:1902186) |
| 0.3 | 2.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.3 | 2.0 | GO:0072599 | establishment of protein localization to endoplasmic reticulum(GO:0072599) |
| 0.3 | 9.8 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.3 | 9.3 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.2 | 3.2 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.2 | 1.5 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.2 | 2.5 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.2 | 2.0 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.2 | 7.8 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.2 | 18.5 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.2 | 5.6 | GO:0071498 | cellular response to fluid shear stress(GO:0071498) |
| 0.2 | 1.2 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.2 | 0.7 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.2 | 2.5 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.2 | 3.8 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.2 | 1.6 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.2 | 0.9 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 0.2 | 1.6 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
| 0.2 | 1.3 | GO:0042976 | activation of Janus kinase activity(GO:0042976) |
| 0.2 | 11.7 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.2 | 2.1 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.2 | 0.4 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 0.2 | 1.5 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.2 | 0.8 | GO:0003340 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339) negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) |
| 0.2 | 6.7 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.2 | 1.6 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.2 | 3.1 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 1.8 | GO:0060546 | negative regulation of necroptotic process(GO:0060546) |
| 0.2 | 9.8 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.2 | 0.4 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 0.2 | 3.2 | GO:1901186 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186) |
| 0.2 | 1.3 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.2 | 0.6 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.2 | 3.8 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.2 | 5.6 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.2 | 0.7 | GO:0035937 | estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 0.2 | 4.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 4.1 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.2 | 1.8 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 0.8 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.2 | 0.5 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961) |
| 0.2 | 0.8 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.2 | 3.9 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.2 | 7.8 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.2 | 0.5 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.2 | 1.8 | GO:0090382 | phagosome maturation(GO:0090382) |
| 0.2 | 1.4 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.2 | 1.2 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.2 | 3.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.2 | 3.6 | GO:1901998 | toxin transport(GO:1901998) |
| 0.2 | 0.2 | GO:0032071 | regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.1 | 17.2 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.1 | 4.2 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.1 | 0.9 | GO:0097104 | postsynaptic membrane assembly(GO:0097104) |
| 0.1 | 1.0 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.1 | 0.7 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.1 | 0.7 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 2.6 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.1 | 3.7 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 0.5 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.1 | 0.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 7.0 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.1 | 0.6 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.1 | 0.6 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) |
| 0.1 | 0.6 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897) |
| 0.1 | 0.3 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.1 | 0.1 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.1 | 0.2 | GO:0071389 | cellular response to mineralocorticoid stimulus(GO:0071389) |
| 0.1 | 0.6 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.1 | 0.9 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 2.1 | GO:0003382 | epithelial cell morphogenesis(GO:0003382) |
| 0.1 | 11.2 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.1 | 1.4 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 2.8 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 1.2 | GO:0044705 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.1 | 1.6 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.1 | 0.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.7 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 1.7 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.1 | 0.8 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 1.1 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 2.0 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.1 | 0.2 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.1 | 1.1 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
| 0.0 | 2.8 | GO:0045333 | cellular respiration(GO:0045333) |
| 0.0 | 3.3 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 2.7 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.3 | GO:0051205 | protein insertion into membrane(GO:0051205) |
| 0.0 | 0.3 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.0 | 0.8 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 0.5 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.6 | GO:0032232 | negative regulation of actin filament bundle assembly(GO:0032232) |
| 0.0 | 0.1 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 0.0 | 0.3 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.0 | 0.3 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.3 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.0 | 0.3 | GO:0010226 | response to lithium ion(GO:0010226) |
| 0.0 | 1.3 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.0 | 0.1 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.0 | 0.6 | GO:0018208 | protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208) |
| 0.0 | 0.1 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.1 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 0.5 | GO:0046037 | GMP metabolic process(GO:0046037) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 26.9 | 80.8 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 19.6 | 58.9 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 12.2 | 36.6 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 10.3 | 41.1 | GO:1990423 | RZZ complex(GO:1990423) |
| 10.2 | 30.7 | GO:0034515 | proteasome storage granule(GO:0034515) |
| 8.7 | 43.3 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 8.6 | 102.8 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 8.0 | 23.9 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 7.7 | 46.1 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 7.3 | 21.9 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 7.1 | 35.4 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 7.0 | 62.7 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 6.7 | 26.8 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 6.6 | 26.4 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 6.5 | 32.5 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 6.3 | 18.8 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 6.2 | 49.9 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 6.2 | 68.1 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 6.0 | 29.8 | GO:0032044 | DSIF complex(GO:0032044) |
| 5.7 | 28.7 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 5.7 | 22.9 | GO:0000811 | GINS complex(GO:0000811) |
| 5.7 | 56.7 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 5.6 | 16.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 5.6 | 55.5 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 5.5 | 55.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 5.2 | 36.7 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 5.2 | 36.2 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 5.1 | 30.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 5.0 | 30.0 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 5.0 | 14.9 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 5.0 | 64.4 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 4.8 | 24.0 | GO:0001940 | male pronucleus(GO:0001940) |
| 4.8 | 19.0 | GO:0005715 | late recombination nodule(GO:0005715) |
| 4.6 | 13.8 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 4.6 | 41.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 4.6 | 41.0 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 4.5 | 26.8 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 4.5 | 13.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 4.4 | 13.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 4.4 | 26.3 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 4.4 | 122.1 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 4.3 | 13.0 | GO:0033167 | ARC complex(GO:0033167) |
| 4.0 | 12.1 | GO:0097414 | glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038) |
| 3.9 | 46.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 3.8 | 30.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 3.7 | 11.2 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 3.7 | 18.7 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 3.7 | 63.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 3.7 | 37.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 3.6 | 46.6 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 3.5 | 14.2 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 3.5 | 24.5 | GO:0090661 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 3.5 | 13.9 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 3.5 | 48.4 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 3.4 | 10.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 3.4 | 27.4 | GO:0048500 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 3.3 | 29.8 | GO:0070652 | HAUS complex(GO:0070652) |
| 3.2 | 15.8 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 3.2 | 19.0 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 3.2 | 9.5 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 3.0 | 15.1 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 3.0 | 54.2 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 2.8 | 8.5 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 2.8 | 25.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 2.8 | 11.1 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 2.8 | 41.3 | GO:0034709 | methylosome(GO:0034709) |
| 2.6 | 7.9 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 2.6 | 7.9 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 2.6 | 33.9 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 2.6 | 2.6 | GO:0071920 | cleavage body(GO:0071920) |
| 2.5 | 30.4 | GO:0005688 | U6 snRNP(GO:0005688) |
| 2.4 | 14.6 | GO:0061617 | MICOS complex(GO:0061617) |
| 2.4 | 9.5 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 2.3 | 14.0 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 2.3 | 66.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 2.3 | 36.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 2.2 | 6.6 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 2.2 | 10.9 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 2.2 | 17.4 | GO:0000796 | condensin complex(GO:0000796) |
| 2.2 | 28.3 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 2.2 | 32.6 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 2.1 | 17.0 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 2.1 | 25.1 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 2.1 | 122.6 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 2.1 | 16.6 | GO:0005827 | polar microtubule(GO:0005827) |
| 2.1 | 4.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 2.1 | 12.3 | GO:0070545 | PeBoW complex(GO:0070545) |
| 2.0 | 42.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 2.0 | 8.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 2.0 | 8.0 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 2.0 | 15.9 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 1.9 | 13.6 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 1.9 | 21.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 1.9 | 5.8 | GO:0034657 | GID complex(GO:0034657) |
| 1.9 | 9.5 | GO:0005685 | U1 snRNP(GO:0005685) |
| 1.9 | 9.4 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 1.8 | 9.1 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 1.8 | 10.8 | GO:0005839 | proteasome core complex(GO:0005839) |
| 1.8 | 5.3 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 1.8 | 15.9 | GO:0044754 | autolysosome(GO:0044754) |
| 1.8 | 1.8 | GO:0000346 | transcription export complex(GO:0000346) |
| 1.7 | 5.2 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 1.7 | 27.7 | GO:0097470 | ribbon synapse(GO:0097470) |
| 1.7 | 5.2 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 1.7 | 18.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 1.7 | 13.6 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 1.7 | 30.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.7 | 6.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 1.7 | 5.0 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 1.7 | 18.4 | GO:0000974 | Prp19 complex(GO:0000974) |
| 1.7 | 3.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.7 | 11.6 | GO:0016272 | prefoldin complex(GO:0016272) |
| 1.6 | 123.6 | GO:0015935 | small ribosomal subunit(GO:0015935) |
| 1.6 | 17.9 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 1.6 | 6.3 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 1.6 | 6.3 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 1.5 | 21.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 1.5 | 19.8 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 1.5 | 58.6 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 1.5 | 17.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 1.5 | 17.5 | GO:0071203 | WASH complex(GO:0071203) |
| 1.5 | 68.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 1.4 | 37.4 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 1.4 | 15.8 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 1.4 | 8.5 | GO:1990357 | terminal web(GO:1990357) |
| 1.4 | 23.9 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 1.4 | 9.8 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 1.4 | 5.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 1.3 | 62.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 1.3 | 42.5 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 1.3 | 35.8 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 1.3 | 3.9 | GO:0034455 | t-UTP complex(GO:0034455) |
| 1.3 | 2.6 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 1.3 | 8.9 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 1.3 | 8.9 | GO:0090543 | Flemming body(GO:0090543) |
| 1.3 | 20.2 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 1.3 | 44.2 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 1.3 | 208.0 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.2 | 30.0 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 1.2 | 9.9 | GO:0070187 | telosome(GO:0070187) |
| 1.2 | 26.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 1.2 | 29.1 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 1.2 | 3.6 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 1.2 | 38.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 1.2 | 9.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.2 | 26.5 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 1.2 | 6.9 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 1.1 | 9.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 1.1 | 4.5 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 1.1 | 60.9 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 1.1 | 26.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 1.1 | 2.2 | GO:0055087 | Ski complex(GO:0055087) |
| 1.1 | 5.5 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 1.1 | 4.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 1.1 | 10.6 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 1.0 | 54.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 1.0 | 3.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 1.0 | 65.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 1.0 | 3.0 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 1.0 | 8.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 1.0 | 10.5 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.9 | 10.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.9 | 19.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.9 | 3.7 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.9 | 9.2 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.9 | 4.6 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.9 | 2.7 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 0.9 | 8.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.8 | 4.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.8 | 11.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.8 | 2.4 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.8 | 3.2 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.8 | 6.3 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.8 | 2.4 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.8 | 13.1 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.8 | 57.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.8 | 3.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.8 | 8.3 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.7 | 20.7 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.7 | 5.1 | GO:0030891 | VCB complex(GO:0030891) |
| 0.7 | 5.7 | GO:0034464 | BBSome(GO:0034464) |
| 0.7 | 8.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.7 | 4.3 | GO:0033063 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.7 | 15.6 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.7 | 7.7 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.7 | 13.3 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.7 | 82.2 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.7 | 7.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.7 | 4.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.7 | 18.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.7 | 7.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.7 | 33.1 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.7 | 2.0 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.7 | 41.3 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.7 | 8.5 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.6 | 67.3 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.6 | 4.5 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.6 | 20.9 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.6 | 31.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.6 | 2.9 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.6 | 20.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.6 | 133.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.6 | 55.7 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.5 | 6.0 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.5 | 11.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.5 | 8.0 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.5 | 8.9 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.5 | 5.7 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.5 | 14.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.5 | 10.9 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 0.5 | 8.1 | GO:0000776 | kinetochore(GO:0000776) |
| 0.5 | 2.5 | GO:0045120 | pronucleus(GO:0045120) |
| 0.5 | 3.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.5 | 3.8 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.5 | 24.1 | GO:0002102 | podosome(GO:0002102) |
| 0.5 | 12.8 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.5 | 12.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.4 | 4.0 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.4 | 2.2 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.4 | 122.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.4 | 18.3 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.4 | 62.2 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.4 | 2.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.4 | 1.2 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.4 | 1.6 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.4 | 1.6 | GO:0035841 | new growing cell tip(GO:0035841) |
| 0.4 | 1.2 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.4 | 6.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.4 | 16.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.4 | 11.3 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.4 | 24.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.4 | 1.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.4 | 5.3 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.3 | 16.1 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.3 | 49.1 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.3 | 3.1 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.3 | 1.3 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.3 | 3.6 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.3 | 1.9 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.3 | 3.6 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.3 | 31.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.3 | 23.8 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.3 | 8.9 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 1.2 | GO:0033503 | HULC complex(GO:0033503) |
| 0.2 | 3.1 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.2 | 34.2 | GO:0005819 | spindle(GO:0005819) |
| 0.2 | 3.0 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 2.0 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.2 | 4.0 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 0.2 | 20.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.2 | 50.3 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) |
| 0.2 | 2.7 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 1.7 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.2 | 2.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.2 | 1.8 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.2 | 149.3 | GO:0005730 | nucleolus(GO:0005730) |
| 0.2 | 4.0 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 0.2 | 11.9 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.2 | 16.1 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.2 | 43.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.2 | 13.2 | GO:0016605 | PML body(GO:0016605) |
| 0.2 | 0.5 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.1 | 19.4 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.1 | 0.4 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.1 | 2.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 3.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 0.5 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 5.3 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 0.9 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.9 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 0.2 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 10.3 | GO:0031966 | mitochondrial membrane(GO:0031966) |
| 0.0 | 12.8 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 0.9 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.1 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 0.0 | 2.0 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 0.2 | GO:0000938 | GARP complex(GO:0000938) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.4 | 37.1 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 11.0 | 54.9 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 10.6 | 74.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 10.4 | 41.4 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 10.2 | 30.5 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 9.8 | 29.3 | GO:0004638 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 9.3 | 37.1 | GO:0070404 | NADH binding(GO:0070404) |
| 8.9 | 53.3 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 8.2 | 48.9 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 8.1 | 48.4 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 8.0 | 40.1 | GO:0017161 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 8.0 | 103.8 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 7.8 | 23.4 | GO:0003896 | DNA primase activity(GO:0003896) |
| 7.5 | 30.0 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 7.3 | 21.9 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 7.2 | 36.2 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 7.2 | 28.7 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
| 7.0 | 49.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 6.9 | 20.7 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 6.8 | 20.4 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 6.7 | 20.0 | GO:0044594 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594) |
| 6.6 | 19.9 | GO:0070538 | oleic acid binding(GO:0070538) |
| 6.3 | 25.1 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 6.3 | 31.3 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 6.1 | 18.2 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 6.0 | 53.7 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 5.8 | 29.2 | GO:1903135 | cupric ion binding(GO:1903135) |
| 5.8 | 17.5 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 5.6 | 16.8 | GO:0048030 | disaccharide binding(GO:0048030) |
| 5.4 | 32.6 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 5.3 | 16.0 | GO:0000035 | acyl binding(GO:0000035) |
| 5.3 | 16.0 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 5.3 | 15.9 | GO:0031208 | POZ domain binding(GO:0031208) |
| 5.3 | 148.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 5.3 | 15.8 | GO:0034512 | box C/D snoRNA binding(GO:0034512) |
| 5.1 | 30.7 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 5.1 | 30.4 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 5.0 | 15.0 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 4.9 | 19.5 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 4.8 | 43.3 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 4.8 | 19.2 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 4.8 | 19.2 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 4.8 | 9.5 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 4.7 | 33.2 | GO:0102344 | 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345) |
| 4.5 | 13.4 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 4.4 | 39.4 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 4.2 | 41.8 | GO:0042731 | PH domain binding(GO:0042731) |
| 4.2 | 49.9 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 4.1 | 53.1 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 3.9 | 27.5 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 3.9 | 23.5 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 3.8 | 15.1 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 3.8 | 11.3 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 3.8 | 49.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 3.7 | 11.1 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 3.6 | 10.9 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 3.6 | 14.3 | GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 3.5 | 10.6 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 3.5 | 49.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 3.5 | 24.5 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 3.4 | 6.8 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 3.4 | 33.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 3.4 | 13.5 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 3.4 | 64.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 3.3 | 36.4 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 3.2 | 19.3 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 3.1 | 83.3 | GO:0070628 | proteasome binding(GO:0070628) |
| 3.1 | 12.3 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 3.1 | 15.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 3.0 | 48.6 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 3.0 | 123.4 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 3.0 | 54.0 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 2.9 | 8.8 | GO:0047787 | geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787) |
| 2.9 | 17.5 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 2.8 | 16.8 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 2.8 | 19.3 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 2.7 | 10.9 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 2.7 | 106.7 | GO:0000049 | tRNA binding(GO:0000049) |
| 2.6 | 20.9 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 2.6 | 12.8 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 2.6 | 12.8 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 2.6 | 7.7 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 2.4 | 7.3 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 2.4 | 7.3 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 2.4 | 21.5 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 2.4 | 21.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 2.4 | 113.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 2.4 | 16.5 | GO:0005347 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217) |
| 2.3 | 32.8 | GO:0016886 | ligase activity, forming phosphoric ester bonds(GO:0016886) |
| 2.3 | 6.9 | GO:0098519 | polynucleotide 5'-phosphatase activity(GO:0004651) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 2.3 | 97.3 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 2.2 | 6.7 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 2.2 | 26.6 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 2.2 | 61.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 2.2 | 26.3 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 2.2 | 39.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 2.2 | 8.7 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 2.2 | 15.3 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 2.2 | 8.6 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 2.1 | 34.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 2.1 | 10.7 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 2.1 | 81.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 2.1 | 8.5 | GO:0043515 | kinetochore binding(GO:0043515) |
| 2.1 | 17.0 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 2.1 | 95.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 2.1 | 75.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 2.1 | 23.0 | GO:0015266 | protein channel activity(GO:0015266) |
| 2.1 | 6.3 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 2.0 | 28.6 | GO:0031386 | protein tag(GO:0031386) |
| 2.0 | 8.2 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 2.0 | 20.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 2.0 | 8.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 2.0 | 4.1 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 2.0 | 6.1 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 2.0 | 16.0 | GO:0015288 | porin activity(GO:0015288) |
| 2.0 | 35.8 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 2.0 | 19.8 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 2.0 | 7.8 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 1.9 | 7.7 | GO:0070990 | snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446) |
| 1.9 | 5.8 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 1.9 | 24.9 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 1.9 | 13.4 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 1.9 | 22.6 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 1.9 | 7.5 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 1.8 | 9.2 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.8 | 138.6 | GO:0019003 | GDP binding(GO:0019003) |
| 1.8 | 5.5 | GO:0004772 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 1.8 | 9.0 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 1.8 | 1.8 | GO:0016419 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 1.8 | 5.4 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889) |
| 1.7 | 14.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 1.7 | 12.2 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 1.7 | 5.2 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 1.7 | 36.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 1.7 | 6.8 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 1.7 | 17.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 1.7 | 114.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 1.7 | 23.6 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 1.7 | 5.0 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 1.7 | 36.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 1.6 | 17.8 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 1.6 | 11.3 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 1.6 | 43.2 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 1.5 | 55.7 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 1.5 | 9.1 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 1.5 | 10.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.5 | 38.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 1.5 | 13.2 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 1.5 | 10.3 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 1.5 | 4.4 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 1.4 | 5.7 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 1.4 | 7.1 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 1.4 | 18.3 | GO:0046790 | virion binding(GO:0046790) |
| 1.4 | 4.2 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 1.4 | 8.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 1.4 | 23.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 1.4 | 12.4 | GO:0089720 | caspase binding(GO:0089720) |
| 1.4 | 16.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 1.4 | 38.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 1.3 | 10.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 1.3 | 6.7 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 1.3 | 5.3 | GO:0033265 | acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265) |
| 1.3 | 29.3 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 1.3 | 29.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 1.3 | 6.6 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 1.3 | 7.9 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.3 | 6.5 | GO:0016936 | galactoside binding(GO:0016936) |
| 1.3 | 5.1 | GO:0002060 | purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184) |
| 1.3 | 15.4 | GO:0043495 | protein anchor(GO:0043495) |
| 1.3 | 2.6 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 1.3 | 3.8 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 1.3 | 2.5 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 1.3 | 5.0 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 1.2 | 17.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 1.2 | 4.9 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 1.2 | 61.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 1.2 | 31.4 | GO:0070840 | dynein complex binding(GO:0070840) |
| 1.2 | 39.5 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 1.2 | 9.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.2 | 42.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 1.2 | 59.8 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 1.2 | 5.8 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 1.2 | 8.1 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 1.1 | 5.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 1.1 | 3.4 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 1.1 | 19.1 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 1.1 | 44.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 1.1 | 3.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.1 | 5.5 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 1.1 | 29.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 1.1 | 3.3 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 1.1 | 5.3 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 1.1 | 17.0 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 1.1 | 10.6 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 1.1 | 7.4 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 1.0 | 11.4 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 1.0 | 28.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 1.0 | 11.3 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 1.0 | 3.0 | GO:0055100 | adiponectin binding(GO:0055100) |
| 1.0 | 5.0 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 1.0 | 10.1 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 1.0 | 7.8 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 1.0 | 5.8 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 1.0 | 25.3 | GO:0001848 | complement binding(GO:0001848) |
| 1.0 | 26.3 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 1.0 | 4.8 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.9 | 12.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.9 | 7.3 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.9 | 10.0 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.9 | 5.5 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.9 | 29.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.9 | 2.6 | GO:0070259 | tyrosyl-DNA phosphodiesterase activity(GO:0070259) |
| 0.9 | 2.6 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.9 | 3.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.9 | 2.6 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.9 | 12.0 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.9 | 20.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.9 | 7.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.9 | 15.4 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 0.8 | 65.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.8 | 9.8 | GO:0016840 | carbon-nitrogen lyase activity(GO:0016840) |
| 0.8 | 2.4 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.8 | 14.5 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.8 | 21.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.8 | 3.2 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.8 | 17.4 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.8 | 8.6 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.8 | 29.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.8 | 13.1 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.8 | 5.4 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.8 | 23.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.8 | 10.7 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.8 | 3.8 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.8 | 3.0 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.8 | 14.3 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.7 | 6.7 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.7 | 20.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.7 | 58.8 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.7 | 15.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.7 | 2.2 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.7 | 2.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.7 | 8.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.7 | 7.8 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.7 | 2.1 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.7 | 4.9 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.7 | 5.6 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.7 | 1.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.7 | 5.5 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.7 | 5.5 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.7 | 34.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.7 | 4.6 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.7 | 8.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.7 | 29.7 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.7 | 130.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.6 | 13.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.6 | 12.8 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.6 | 10.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.6 | 24.0 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.6 | 6.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.6 | 2.5 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.6 | 16.1 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.6 | 37.5 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.6 | 6.1 | GO:0034594 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.6 | 6.0 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.6 | 12.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.6 | 6.0 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.6 | 1.7 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.6 | 4.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.5 | 2.2 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.5 | 13.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.5 | 4.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.5 | 6.5 | GO:0045505 | dynein light chain binding(GO:0045503) dynein intermediate chain binding(GO:0045505) |
| 0.5 | 2.7 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.5 | 19.8 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.5 | 11.0 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.5 | 1.6 | GO:0052854 | (S)-2-hydroxy-acid oxidase activity(GO:0003973) oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854) |
| 0.5 | 7.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.5 | 8.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.5 | 18.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.5 | 1.5 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.5 | 28.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.5 | 2.5 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.5 | 10.9 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.5 | 4.2 | GO:0019158 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.5 | 8.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.5 | 83.5 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.5 | 11.3 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.4 | 9.4 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.4 | 9.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.4 | 5.2 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.4 | 1.3 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 0.4 | 12.7 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.4 | 4.6 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.4 | 7.0 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.4 | 6.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.4 | 3.7 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.4 | 1.9 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.4 | 3.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.4 | 11.4 | GO:0003774 | motor activity(GO:0003774) |
| 0.4 | 35.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.4 | 7.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.4 | 2.6 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.4 | 2.9 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
| 0.4 | 2.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.4 | 5.4 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.4 | 2.2 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.4 | 12.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.4 | 5.0 | GO:0045502 | dynein binding(GO:0045502) |
| 0.4 | 1.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.4 | 1.8 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.3 | 38.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.3 | 15.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.3 | 2.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.3 | 4.4 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.3 | 1.0 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.3 | 3.3 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.3 | 1.3 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.3 | 21.6 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.3 | 5.8 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.3 | 1.3 | GO:0015119 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.3 | 3.5 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.3 | 4.0 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.3 | 1.6 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.3 | 1.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.3 | 1.2 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.3 | 103.3 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.3 | 12.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.3 | 1.7 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.3 | 2.3 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.3 | 4.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.3 | 7.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.3 | 4.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.3 | 8.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.3 | 2.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.3 | 2.5 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.3 | 1.6 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.3 | 0.3 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.3 | 2.8 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.3 | 6.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.2 | 9.5 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.2 | 0.7 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.2 | 1.2 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.2 | 0.9 | GO:0034191 | apolipoprotein A-I receptor binding(GO:0034191) |
| 0.2 | 2.3 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
| 0.2 | 3.9 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.2 | 2.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.2 | 4.7 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.2 | 3.8 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.2 | 0.7 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.2 | 6.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.2 | 2.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.2 | 3.0 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.2 | 1.8 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.2 | 2.9 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.2 | 12.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.2 | 4.6 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.2 | 0.7 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.2 | 9.5 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.2 | 2.2 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
| 0.2 | 30.4 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.2 | 1.5 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.2 | 0.5 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 26.5 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 0.4 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.1 | 14.8 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 1.9 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.5 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.1 | 5.2 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 6.9 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 0.6 | GO:0004619 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.1 | 2.0 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 4.7 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 0.8 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.1 | 1.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 7.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 3.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.1 | 1.5 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 19.3 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.1 | 2.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 47.3 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.1 | 2.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.5 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.1 | 6.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 0.4 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
| 0.1 | 0.4 | GO:0031781 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.1 | 0.2 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 0.1 | GO:0016508 | long-chain-enoyl-CoA hydratase activity(GO:0016508) |
| 0.1 | 1.0 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 1.0 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 0.4 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.3 | GO:0035240 | dopamine binding(GO:0035240) |
| 0.0 | 0.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.1 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.0 | 3.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.7 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 9.4 | GO:0003712 | transcription cofactor activity(GO:0003712) |
| 0.0 | 0.1 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.0 | 0.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 1.6 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.5 | GO:0031593 | polyubiquitin binding(GO:0031593) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 3.0 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 2.3 | 177.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 2.3 | 70.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.9 | 95.0 | PID BARD1 PATHWAY | BARD1 signaling events |
| 1.7 | 66.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 1.6 | 9.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 1.5 | 49.7 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.4 | 91.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 1.4 | 56.4 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 1.4 | 36.9 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 1.3 | 87.5 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 1.3 | 50.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 1.1 | 4.5 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 1.0 | 46.9 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 1.0 | 39.1 | PID MYC PATHWAY | C-MYC pathway |
| 1.0 | 9.2 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 1.0 | 91.1 | PID E2F PATHWAY | E2F transcription factor network |
| 0.9 | 86.3 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.9 | 51.3 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.8 | 30.9 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.8 | 25.0 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.8 | 49.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.8 | 34.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.8 | 9.4 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.8 | 21.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.7 | 58.3 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.7 | 118.0 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.7 | 22.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.7 | 22.7 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.7 | 8.6 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.6 | 5.1 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.6 | 9.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.6 | 10.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.6 | 10.8 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.6 | 55.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.6 | 9.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.6 | 13.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.6 | 16.1 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.6 | 16.1 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.6 | 32.2 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.6 | 8.3 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.6 | 10.5 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.5 | 13.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.5 | 37.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.5 | 22.0 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.5 | 23.3 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.5 | 17.4 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.4 | 6.9 | PID ATM PATHWAY | ATM pathway |
| 0.4 | 2.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.4 | 13.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.4 | 13.0 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.4 | 4.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.3 | 21.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.3 | 7.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.3 | 5.3 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.3 | 6.6 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.3 | 4.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 5.9 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.2 | 2.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.2 | 6.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.2 | 2.9 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.2 | 3.9 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.2 | 1.8 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.2 | 5.6 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 8.1 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.1 | 2.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 4.0 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 4.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 3.1 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 2.2 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.1 | 1.3 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 2.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.9 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.1 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.2 | 83.0 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 6.6 | 26.4 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 4.6 | 316.0 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 4.4 | 70.3 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 4.4 | 21.9 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 4.2 | 46.5 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 4.1 | 61.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 4.0 | 124.5 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 3.8 | 91.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 3.6 | 36.1 | REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX | Genes involved in Formation of the HIV-1 Early Elongation Complex |
| 3.6 | 43.0 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 3.4 | 37.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 3.4 | 131.3 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 3.1 | 94.3 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 2.9 | 57.9 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 2.9 | 74.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 2.8 | 67.4 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 2.7 | 231.5 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 2.7 | 149.0 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 2.7 | 42.5 | REACTOME TRNA AMINOACYLATION | Genes involved in tRNA Aminoacylation |
| 2.5 | 71.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 2.5 | 37.6 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 2.5 | 49.1 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 2.4 | 79.5 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 2.4 | 43.0 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 2.2 | 31.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 2.2 | 70.1 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 2.2 | 32.5 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 2.1 | 14.4 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 2.0 | 60.9 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 2.0 | 36.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 2.0 | 15.9 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 1.9 | 21.4 | REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX | Genes involved in CDT1 association with the CDC6:ORC:origin complex |
| 1.9 | 36.9 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 1.9 | 17.0 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 1.8 | 35.3 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 1.7 | 41.9 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 1.7 | 38.7 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 1.7 | 63.0 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 1.6 | 35.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.6 | 12.8 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 1.6 | 35.2 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 1.6 | 25.1 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 1.5 | 29.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 1.5 | 48.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 1.5 | 21.8 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 1.4 | 6.8 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 1.4 | 40.6 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 1.3 | 97.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 1.3 | 9.1 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 1.3 | 34.7 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 1.2 | 6.2 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 1.2 | 9.9 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 1.2 | 65.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.2 | 21.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 1.2 | 11.6 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 1.2 | 21.9 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 1.1 | 100.1 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 1.1 | 143.4 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 1.1 | 3.3 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 1.1 | 33.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 1.1 | 25.8 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 1.1 | 79.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 1.1 | 22.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 1.1 | 140.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 1.0 | 20.7 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 1.0 | 18.3 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 1.0 | 23.8 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.9 | 26.6 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.9 | 9.0 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.9 | 3.5 | REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | Genes involved in Assembly of the pre-replicative complex |
| 0.9 | 23.9 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.8 | 60.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.8 | 15.4 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.8 | 2.4 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.8 | 22.8 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.8 | 15.6 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.8 | 14.4 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.7 | 17.4 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.7 | 7.8 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.7 | 36.4 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.7 | 10.9 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.7 | 11.5 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.6 | 12.8 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.6 | 8.9 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.6 | 27.5 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.6 | 56.5 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.6 | 2.4 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.5 | 17.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.5 | 8.6 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.5 | 8.9 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.5 | 13.9 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.5 | 75.8 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.5 | 4.9 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.5 | 7.1 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.4 | 12.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.4 | 5.0 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.4 | 9.4 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.4 | 10.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.4 | 6.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.4 | 4.0 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.4 | 8.7 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 0.3 | 7.5 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.3 | 4.1 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.3 | 4.2 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 6.1 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 3.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.2 | 1.7 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.2 | 4.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.2 | 3.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 2.1 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.2 | 4.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.2 | 8.4 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.2 | 6.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 4.5 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.2 | 4.7 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.2 | 1.3 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.1 | 2.5 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 3.2 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 0.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 6.7 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 1.8 | REACTOME SIGNALING BY WNT | Genes involved in Signaling by Wnt |
| 0.1 | 3.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 4.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.7 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 3.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 2.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 2.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 1.5 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 0.8 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 1.5 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 0.7 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 5.1 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.5 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.2 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |