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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BBX

Z-value: 0.40

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Transcription factors associated with BBX

Gene Symbol Gene ID Gene Info
BBX
ENSG00000114439.19 BBX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BBXhg38_v1_chr3_+_107522936_107523003-0.267.6e-05Click!

Activity profile of BBX motif

Sorted Z-values of BBX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_90642855 9.90 ENST00000637905.1
DIRAS2
DIRAS family GTPase 2
chr2_+_200440649 6.48 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr1_-_58577244 4.65 ENST00000371225.4
TACSTD2
tumor associated calcium signal transducer 2
chr2_-_215393126 4.05 ENST00000456923.5
FN1
fibronectin 1
chr16_+_56638659 3.90 ENST00000290705.12
MT1A
metallothionein 1A
chr4_+_154563003 3.70 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr6_+_121437378 3.57 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr7_+_32979445 3.51 ENST00000418354.5
ENST00000490776.3
FKBP9
FKBP prolyl isomerase 9
chr7_-_16833411 2.72 ENST00000412973.1
AGR2
anterior gradient 2, protein disulphide isomerase family member
chr4_-_185775271 2.47 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
SORBS2
sorbin and SH3 domain containing 2
chr9_+_35161951 2.32 ENST00000617908.4
ENST00000619578.4
UNC13B
unc-13 homolog B
chr19_-_14848922 2.07 ENST00000641129.1
OR7A10
olfactory receptor family 7 subfamily A member 10
chr4_-_185775890 2.02 ENST00000437304.6
SORBS2
sorbin and SH3 domain containing 2
chr4_-_185812209 1.72 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
SORBS2
sorbin and SH3 domain containing 2
chr4_+_87650277 1.69 ENST00000339673.11
ENST00000282479.8
DMP1
dentin matrix acidic phosphoprotein 1
chr3_-_169147734 1.66 ENST00000464456.5
MECOM
MDS1 and EVI1 complex locus
chr20_-_31722854 1.64 ENST00000307677.5
BCL2L1
BCL2 like 1
chr15_+_72118392 1.59 ENST00000340912.6
SENP8
SUMO peptidase family member, NEDD8 specific
chr9_+_35162000 1.50 ENST00000396787.5
ENST00000378495.7
ENST00000635942.1
ENST00000378496.8
UNC13B
unc-13 homolog B
chr3_+_151814102 1.46 ENST00000232892.12
AADAC
arylacetamide deacetylase
chr1_-_13285154 1.41 ENST00000357367.6
ENST00000614831.1
PRAMEF8
PRAME family member 8
chr7_+_66075876 1.41 ENST00000395332.8
ASL
argininosuccinate lyase
chr4_+_68447453 1.36 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr14_+_21868822 1.35 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr5_-_56116946 1.35 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr7_-_140924900 1.33 ENST00000646891.1
ENST00000644969.2
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr20_-_31722949 1.33 ENST00000376055.9
BCL2L1
BCL2 like 1
chr20_-_57711536 1.29 ENST00000265626.8
PMEPA1
prostate transmembrane protein, androgen induced 1
chr15_-_74203172 1.28 ENST00000616000.4
STRA6
signaling receptor and transporter of retinol STRA6
chr4_+_69280472 1.23 ENST00000335568.10
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase family 2 member B28
chr6_+_72212802 1.19 ENST00000401910.7
RIMS1
regulating synaptic membrane exocytosis 1
chr12_+_18262730 1.18 ENST00000675017.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr18_-_13915531 1.15 ENST00000327606.4
MC2R
melanocortin 2 receptor
chr14_+_94026314 1.15 ENST00000203664.10
ENST00000553723.1
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr4_-_122621011 1.13 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr12_+_55362975 1.10 ENST00000641576.1
OR6C75
olfactory receptor family 6 subfamily C member 75
chr13_+_27919993 1.07 ENST00000381033.5
PDX1
pancreatic and duodenal homeobox 1
chr20_-_31722533 1.07 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2L1
BCL2 like 1
chr9_-_5833014 1.04 ENST00000339450.10
ERMP1
endoplasmic reticulum metallopeptidase 1
chr9_-_92404559 1.03 ENST00000262551.8
ENST00000375561.10
OGN
osteoglycin
chr5_+_150661243 1.00 ENST00000517768.6
MYOZ3
myozenin 3
chr6_+_31927486 1.00 ENST00000442278.6
C2
complement C2
chr22_+_29438583 0.99 ENST00000354373.2
RFPL1
ret finger protein like 1
chr15_+_89243945 0.98 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FANCI
FA complementation group I
chr6_-_49744434 0.93 ENST00000433368.6
ENST00000354620.4
CRISP3
cysteine rich secretory protein 3
chr18_-_23437927 0.92 ENST00000578520.5
ENST00000383233.8
TMEM241
transmembrane protein 241
chr6_-_25874212 0.92 ENST00000361703.10
ENST00000397060.8
SLC17A3
solute carrier family 17 member 3
chr17_-_44066595 0.91 ENST00000585388.2
ENST00000293406.8
LSM12
LSM12 homolog
chr1_+_117420597 0.90 ENST00000449370.6
MAN1A2
mannosidase alpha class 1A member 2
chr6_+_72212887 0.88 ENST00000523963.5
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_54998927 0.84 ENST00000651561.1
BSND
barttin CLCNK type accessory subunit beta
chr2_+_209653171 0.84 ENST00000447185.5
MAP2
microtubule associated protein 2
chr5_+_150660841 0.83 ENST00000297130.4
MYOZ3
myozenin 3
chr17_-_61591192 0.81 ENST00000521764.3
NACA2
nascent polypeptide associated complex subunit alpha 2
chr4_-_158159657 0.79 ENST00000590648.5
GASK1B
golgi associated kinase 1B
chr6_-_49744378 0.78 ENST00000371159.8
ENST00000263045.9
CRISP3
cysteine rich secretory protein 3
chrX_-_141698739 0.78 ENST00000370515.3
SPANXD
SPANX family member D
chr2_+_102311546 0.76 ENST00000233954.6
ENST00000447231.5
IL1RL1
interleukin 1 receptor like 1
chr6_+_29457155 0.69 ENST00000377133.6
ENST00000377136.5
OR2H1
olfactory receptor family 2 subfamily H member 1
chr2_+_102311502 0.66 ENST00000404917.6
ENST00000410040.5
IL1RL1
IL18R1
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr6_-_160664270 0.65 ENST00000316300.10
LPA
lipoprotein(a)
chr5_+_126423122 0.64 ENST00000515200.5
GRAMD2B
GRAM domain containing 2B
chr12_-_10826358 0.63 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chrX_+_11293411 0.62 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
AMELX
amelogenin X-linked
chr15_-_72118114 0.61 ENST00000356056.10
ENST00000569314.1
MYO9A
myosin IXA
chr4_-_103099811 0.60 ENST00000504285.5
ENST00000296424.9
BDH2
3-hydroxybutyrate dehydrogenase 2
chr5_+_141430565 0.60 ENST00000613314.1
PCDHGA12
protocadherin gamma subfamily A, 12
chr19_+_7763210 0.58 ENST00000359059.10
ENST00000596363.5
ENST00000394122.7
ENST00000327325.10
CLEC4M
C-type lectin domain family 4 member M
chr4_+_70592253 0.57 ENST00000322937.10
ENST00000613447.4
AMBN
ameloblastin
chr2_-_61854119 0.56 ENST00000405894.3
FAM161A
FAM161 centrosomal protein A
chr1_-_216805367 0.56 ENST00000360012.7
ESRRG
estrogen related receptor gamma
chr14_+_20110739 0.53 ENST00000641386.2
ENST00000641633.2
OR4K17
olfactory receptor family 4 subfamily K member 17
chr11_+_58622659 0.52 ENST00000361987.6
CNTF
ciliary neurotrophic factor
chr5_+_141135199 0.52 ENST00000231134.8
ENST00000623915.1
PCDHB5
protocadherin beta 5
chr4_-_67701113 0.50 ENST00000420827.2
ENST00000322244.10
UBA6
ubiquitin like modifier activating enzyme 6
chr5_+_141182369 0.50 ENST00000609684.3
ENST00000625044.1
ENST00000623407.1
ENST00000623884.1
PCDHB16
ENSG00000279068.1
protocadherin beta 16
novel transcript
chr3_+_98147479 0.49 ENST00000641380.1
OR5H14
olfactory receptor family 5 subfamily H member 14
chr2_-_61854013 0.49 ENST00000404929.6
FAM161A
FAM161 centrosomal protein A
chr9_-_92482499 0.43 ENST00000375544.7
ASPN
asporin
chr7_+_117480011 0.41 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CFTR
CF transmembrane conductance regulator
chr5_-_22853320 0.40 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr17_+_21126947 0.39 ENST00000579303.5
DHRS7B
dehydrogenase/reductase 7B
chr9_-_2844058 0.34 ENST00000397885.3
PUM3
pumilio RNA binding family member 3
chr19_+_9250930 0.31 ENST00000456448.3
OR7E24
olfactory receptor family 7 subfamily E member 24
chr6_+_52420107 0.27 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EFHC1
EF-hand domain containing 1
chr3_+_148865288 0.26 ENST00000296046.4
CPA3
carboxypeptidase A3
chr20_-_7940444 0.24 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr17_+_68259164 0.21 ENST00000448504.6
ARSG
arylsulfatase G
chr9_-_92482350 0.16 ENST00000375543.2
ASPN
asporin
chr8_-_6926066 0.14 ENST00000297436.3
DEFA6
defensin alpha 6
chr12_-_8612850 0.11 ENST00000229335.11
ENST00000537228.5
AICDA
activation induced cytidine deaminase
chr2_+_33436304 0.11 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr10_-_92243246 0.09 ENST00000412050.8
ENST00000614585.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr4_+_94489030 0.06 ENST00000510099.5
PDLIM5
PDZ and LIM domain 5
chr12_-_16600703 0.05 ENST00000616247.4
LMO3
LIM domain only 3
chr5_+_141430499 0.03 ENST00000252085.4
PCDHGA12
protocadherin gamma subfamily A, 12
chr6_-_29375291 0.02 ENST00000396806.3
OR12D3
olfactory receptor family 12 subfamily D member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.3 3.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.9 3.6 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.7 4.6 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.6 4.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.5 2.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.4 1.4 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.3 3.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 0.9 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.3 1.1 GO:0010157 response to chlorate(GO:0010157)
0.3 1.6 GO:0016926 protein desumoylation(GO:0016926)
0.2 2.3 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.9 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 1.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 3.9 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 6.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.6 GO:0046968 peptide antigen transport(GO:0046968)
0.1 1.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.9 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 0.4 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 2.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.5 GO:0021764 amygdala development(GO:0021764)
0.1 0.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 1.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 2.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 5.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 1.2 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.7 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 8.5 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.1 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.8 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0002003 angiotensin maturation(GO:0002003)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0044305 calyx of Held(GO:0044305)
0.6 7.7 GO:0005577 fibrinogen complex(GO:0005577)
0.3 4.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 3.6 GO:0005922 connexon complex(GO:0005922)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 4.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 8.0 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.5 1.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 1.4 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.3 4.0 GO:0051434 BH3 domain binding(GO:0051434)
0.3 0.9 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3 1.8 GO:0051373 FATZ binding(GO:0051373)
0.3 2.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 6.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.6 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 0.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 3.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 1.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 3.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 3.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.6 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.2 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 7.7 GO:0051087 chaperone binding(GO:0051087)
0.1 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 5.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 1.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 7.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 3.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 5.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 3.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 3.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport