Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for BPTF
Z-value: 1.92
Motif logo
Transcription factors associated with BPTF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BPTF | hg38_v1_chr17_+_67825494_67825528 | 0.58 | 1.1e-20 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BPTF
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 222.4 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 2.2 | 167.0 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 2.2 | 86.5 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.1 | 84.3 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.8 | 79.0 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 5.5 | 77.0 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 5.3 | 74.8 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.9 | 71.5 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 1.0 | 64.8 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 1.4 | 58.9 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 233.1 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.9 | 162.8 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 3.4 | 94.8 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.5 | 93.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.5 | 79.6 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 5.9 | 77.0 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 10.8 | 75.3 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.2 | 75.1 | GO:0005925 | focal adhesion(GO:0005925) |
| 5.5 | 71.1 | GO:0005688 | U6 snRNP(GO:0005688) |
| 4.7 | 65.5 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 251.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.4 | 173.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 133.4 | GO:0003723 | RNA binding(GO:0003723) |
| 3.3 | 92.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 2.2 | 85.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.6 | 75.4 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 7.4 | 73.7 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 12.2 | 72.9 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.4 | 69.8 | GO:0042393 | histone binding(GO:0042393) |
| 0.8 | 67.7 | GO:0047485 | protein N-terminus binding(GO:0047485) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 94.1 | PID P53 REGULATION PATHWAY | p53 pathway |
| 1.4 | 84.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 2.4 | 84.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.8 | 79.2 | PID E2F PATHWAY | E2F transcription factor network |
| 0.7 | 73.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 1.0 | 56.7 | PID ATR PATHWAY | ATR signaling pathway |
| 1.3 | 52.8 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.7 | 48.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.7 | 46.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 1.6 | 46.1 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 233.5 | REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS | Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins |
| 1.2 | 176.8 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 1.5 | 128.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.7 | 100.8 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.6 | 100.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.1 | 96.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 2.5 | 95.3 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 1.6 | 77.3 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 1.5 | 77.1 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 4.9 | 73.9 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |