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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BPTF

Z-value: 1.92

Motif logo

Transcription factors associated with BPTF

Gene Symbol Gene ID Gene Info
ENSG00000171634.18 BPTF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BPTFhg38_v1_chr17_+_67825494_678255280.581.1e-20Click!

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_4796144 44.97 ENST00000614486.4
ENST00000270586.8
proteasome 20S subunit beta 6
chr2_+_215312028 44.08 ENST00000236959.14
ENST00000435675.5
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_+_160421847 39.46 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr6_+_34757473 38.22 ENST00000244520.10
ENST00000374018.5
ENST00000374017.3
small nuclear ribonucleoprotein polypeptide C
chr2_-_224569782 33.56 ENST00000409096.5
cullin 3
chr14_+_55661272 33.52 ENST00000555573.5
kinectin 1
chr5_+_172958729 32.93 ENST00000519974.5
ENST00000521476.5
ribosomal protein L26 like 1
chr7_+_141738321 32.80 ENST00000612337.4
single stranded DNA binding protein 1
chr1_-_8878018 32.08 ENST00000646660.1
ENST00000646906.1
enolase 1
chr3_+_172039556 31.00 ENST00000415807.7
ENST00000421757.5
fibronectin type III domain containing 3B
chr8_-_86514332 30.64 ENST00000523911.5
regulator of microtubule dynamics 1
chr16_+_67570741 29.34 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CCCTC-binding factor
chr7_+_55365317 28.73 ENST00000254770.3
LanC like 2
chr19_+_49676140 28.53 ENST00000527382.5
ENST00000528623.5
protein arginine methyltransferase 1
chr22_-_41690462 27.60 ENST00000648350.1
ENST00000402458.1
small nuclear ribonucleoprotein 13
chr1_+_44746401 27.33 ENST00000372217.5
kinesin family member 2C
chr22_-_41940208 26.91 ENST00000472374.6
centromere protein M
chr5_+_74715503 26.81 ENST00000513336.5
hexosaminidase subunit beta
chr14_+_35278618 26.72 ENST00000540871.5
proteasome 20S subunit alpha 6
chr7_+_55951919 26.71 ENST00000443449.1
mitochondrial ribosomal protein S17
chr7_+_55951852 26.32 ENST00000285298.9
mitochondrial ribosomal protein S17
chr12_-_110450298 26.19 ENST00000426440.5
ENST00000228825.12
actin related protein 2/3 complex subunit 3
chr9_-_83978429 26.16 ENST00000351839.7
heterogeneous nuclear ribonucleoprotein K
chr2_+_74206384 25.74 ENST00000678623.1
ENST00000678731.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr7_-_6826770 25.33 ENST00000626257.2
CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated
chr2_+_101839815 25.06 ENST00000421882.5
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_150234668 24.99 ENST00000616917.4
acidic nuclear phosphoprotein 32 family member E
chr4_+_56978858 24.62 ENST00000431623.6
ENST00000441246.6
RNA polymerase II subunit B
chr21_-_29061351 24.51 ENST00000432178.5
chaperonin containing TCP1 subunit 8
chr6_+_24774925 24.15 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr16_+_3018390 23.75 ENST00000573001.5
TNF receptor superfamily member 12A
chr12_-_56752311 23.72 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr6_-_8102046 23.33 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr3_-_72446623 22.86 ENST00000477973.4
RING1 and YY1 binding protein
chr2_+_108607140 22.74 ENST00000410093.5
LIM zinc finger domain containing 1
chr1_+_165895564 22.69 ENST00000469256.6
uridine-cytidine kinase 2
chr10_+_113679159 22.66 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7
chr13_-_37105664 22.47 ENST00000379800.4
casein kinase 1 alpha 1 like
chr5_+_83471925 22.04 ENST00000502527.2
versican
chr3_+_184174846 21.88 ENST00000427072.5
ENST00000411763.6
ENST00000292807.9
ENST00000448139.5
ENST00000455925.1
adaptor related protein complex 2 subunit mu 1
chr14_+_55123917 21.67 ENST00000553493.5
galectin 3
chr19_+_10251901 20.99 ENST00000592514.5
ENST00000307422.9
ENST00000590150.5
ENST00000590669.5
mitochondrial ribosomal protein L4
chr15_+_63529142 20.95 ENST00000268049.11
ubiquitin specific peptidase 3
chr5_+_168486462 20.94 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr4_+_56978877 20.61 ENST00000433463.1
ENST00000314595.6
RNA polymerase II subunit B
chr5_+_163505564 20.49 ENST00000421814.6
ENST00000518095.5
ENST00000321757.11
methionine adenosyltransferase 2B
chr1_-_45542726 20.47 ENST00000676549.1
peroxiredoxin 1
chr2_-_61500568 20.45 ENST00000677476.1
exportin 1
chr1_+_165895583 20.38 ENST00000470820.1
uridine-cytidine kinase 2
chrX_+_49171918 20.25 ENST00000376322.7
proteolipid protein 2
chr1_+_92832065 20.20 ENST00000315741.5
ribosomal protein L5
chr4_-_83114715 19.97 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr14_+_73097027 19.90 ENST00000532192.1
RNA binding motif protein 25
chr1_+_203861575 19.89 ENST00000414487.7
small nuclear ribonucleoprotein polypeptide E
chr17_+_68525795 19.88 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr17_+_17179527 19.86 ENST00000579361.1
myosin phosphatase Rho interacting protein
chr12_+_15911324 19.70 ENST00000524480.5
ENST00000428559.7
ENST00000531803.5
ENST00000532964.5
deoxyribose-phosphate aldolase
chr17_+_47651061 19.57 ENST00000540627.5
karyopherin subunit beta 1
chr1_-_53940100 19.46 ENST00000371376.1
heat shock protein family B (small) member 11
chr5_-_134174765 19.43 ENST00000520417.1
S-phase kinase associated protein 1
chr19_+_6361743 19.23 ENST00000597326.6
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr9_+_73151833 19.22 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
annexin A1
chr11_-_62671540 19.09 ENST00000532208.5
ENST00000377954.3
ENST00000431002.6
ENST00000354588.7
ENST00000415855.6
LBH domain containing 1
chr7_+_141738343 18.86 ENST00000498107.5
ENST00000265304.11
ENST00000467681.5
ENST00000465582.5
ENST00000463093.5
single stranded DNA binding protein 1
chr1_-_154608705 18.71 ENST00000649749.1
ENST00000648871.1
adenosine deaminase RNA specific
chr12_-_56741535 18.68 ENST00000647707.1
novel protein
chr19_+_52429181 18.67 ENST00000301085.8
zinc finger protein 534
chr2_+_200305873 18.45 ENST00000439084.5
ENST00000409718.5
spermatogenesis associated serine rich 2 like
chr2_+_186506713 18.43 ENST00000445547.1
zinc finger CCCH-type containing 15
chr5_+_65926556 18.21 ENST00000380943.6
ENST00000416865.6
ENST00000380935.5
ENST00000284037.10
erbb2 interacting protein
chr19_+_54115726 18.12 ENST00000445811.5
ENST00000321030.9
ENST00000445124.5
ENST00000447810.5
pre-mRNA processing factor 31
chr1_+_223701582 17.87 ENST00000433674.6
calpain 2
chr17_+_68035636 17.80 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
karyopherin subunit alpha 2
chr14_+_54396964 17.69 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr18_-_36122110 17.65 ENST00000586829.1
solute carrier family 39 member 6
chr12_-_110445540 17.60 ENST00000547365.1
actin related protein 2/3 complex subunit 3
chr12_-_102062079 17.50 ENST00000545679.5
WASH complex subunit 3
chr6_-_31540536 17.50 ENST00000376177.6
DExD-box helicase 39B
chr1_-_145405778 17.29 ENST00000392971.6
NBPF member 20
chr1_-_15809348 17.27 ENST00000483273.2
ubiquinol-cytochrome c reductase hinge protein like
chr2_+_180981108 17.17 ENST00000602710.5
ubiquitin conjugating enzyme E2 E3
chr7_-_105522264 17.15 ENST00000469408.6
pseudouridine synthase 7
chr12_-_56752366 17.14 ENST00000672280.1
DNA primase subunit 1
chr1_+_92832005 17.13 ENST00000645300.1
ribosomal protein L5
chrX_+_103356446 17.09 ENST00000372656.5
ENST00000372661.6
ENST00000646896.1
transcription elongation factor A like 9
chr17_+_68035722 17.02 ENST00000679078.1
ENST00000330459.8
ENST00000584026.6
karyopherin subunit alpha 2
chr3_-_130746760 16.88 ENST00000356763.8
phosphoinositide-3-kinase regulatory subunit 4
chr14_-_21383989 16.86 ENST00000216297.7
SPT16 homolog, facilitates chromatin remodeling subunit
chr6_-_24719146 16.80 ENST00000378119.9
chromosome 6 open reading frame 62
chr7_-_100101915 16.79 ENST00000621318.4
ENST00000343023.10
minichromosome maintenance complex component 7
chr12_-_102061946 16.77 ENST00000240079.11
WASH complex subunit 3
chr16_-_8975320 16.74 ENST00000673704.1
ubiquitin specific peptidase 7
chr2_-_149587602 16.73 ENST00000428879.5
ENST00000303319.10
ENST00000422782.2
metabolism of cobalamin associated D
chr2_+_200306048 16.68 ENST00000409988.7
ENST00000409385.5
spermatogenesis associated serine rich 2 like
chr3_+_184300564 16.65 ENST00000435761.5
ENST00000439383.5
proteasome 26S subunit, non-ATPase 2
chr7_-_6826275 16.59 ENST00000316731.13
CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated
chr7_-_88226965 16.26 ENST00000490437.5
ENST00000431660.5
sorcin
chr11_-_77637751 16.11 ENST00000263309.7
ENST00000525064.5
chloride nucleotide-sensitive channel 1A
chr2_-_150487658 16.08 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr7_-_88226987 16.06 ENST00000394641.7
sorcin
chr7_+_16661182 16.00 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr16_+_85798541 15.94 ENST00000565078.5
cytochrome c oxidase subunit 4I1
chr1_-_193106048 15.86 ENST00000367440.3
glutaredoxin 2
chr18_+_3451585 15.83 ENST00000551541.5
TGFB induced factor homeobox 1
chr3_-_52535006 15.73 ENST00000307076.8
5'-nucleotidase domain containing 2
chr1_-_244862381 15.64 ENST00000640001.1
ENST00000639628.1
heterogeneous nuclear ribonucleoprotein U
chr4_-_70839343 15.56 ENST00000514161.5
ENST00000499044.6
G-rich RNA sequence binding factor 1
chr19_-_42232149 15.55 ENST00000678490.1
ENST00000677025.1
ENST00000677702.1
novel protein
glycogen synthase kinase 3 alpha
chr10_+_13610047 15.53 ENST00000601460.5
novel protein
chr8_-_63026179 15.52 ENST00000677919.1
gamma-glutamyl hydrolase
chr2_-_61888570 15.48 ENST00000394440.8
ENST00000544079.2
chaperonin containing TCP1 subunit 4
chr15_-_60398733 15.48 ENST00000559818.6
annexin A2
chr5_-_69369988 15.45 ENST00000380818.7
ENST00000328663.8
adenylate kinase 6
TATA-box binding protein associated factor 9
chr15_+_41332862 15.44 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr13_-_36999295 15.31 ENST00000679673.1
ENST00000679572.1
ENST00000239891.4
ENST00000681763.1
ENST00000680671.1
ENST00000680012.1
ENST00000679837.1
ENST00000443765.6
ALG5 dolichyl-phosphate beta-glucosyltransferase
chr7_+_65373873 15.31 ENST00000450302.2
zinc finger protein 92
chr2_+_231056845 15.27 ENST00000677230.1
ENST00000677259.1
ENST00000677180.1
ENST00000409643.6
ENST00000619128.5
ENST00000678679.1
ENST00000676740.1
ENST00000308696.11
ENST00000440838.5
ENST00000373635.9
proteasome 26S subunit, non-ATPase 1
chr7_+_65373799 15.25 ENST00000357512.3
zinc finger protein 92
chr2_-_168913277 15.16 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr14_+_90397056 15.15 ENST00000553542.5
calmodulin 1
chr5_+_83471764 15.15 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr11_-_58575846 15.08 ENST00000395074.7
leupaxin
chr5_-_143400716 15.07 ENST00000424646.6
ENST00000652686.1
nuclear receptor subfamily 3 group C member 1
chr7_+_65373839 15.04 ENST00000431504.1
ENST00000328747.12
zinc finger protein 92
chr6_-_30744537 15.02 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr15_+_65550819 15.02 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr19_+_7348930 14.92 ENST00000668164.2
Rho/Rac guanine nucleotide exchange factor 18
chr15_-_63157991 14.91 ENST00000411926.1
ribosomal protein S27 like
chr5_+_163503075 14.86 ENST00000280969.9
methionine adenosyltransferase 2B
chr18_+_32091849 14.85 ENST00000261593.8
ENST00000578914.1
ring finger protein 138
chr22_+_24555981 14.84 ENST00000215829.8
ENST00000402849.5
small nuclear ribonucleoprotein D3 polypeptide
chr17_-_79009731 14.81 ENST00000392446.10
ENST00000590370.5
ENST00000591625.5
calcium activated nucleotidase 1
chr14_-_58427489 14.73 ENST00000555593.5
translocase of inner mitochondrial membrane 9
chr16_-_28610032 14.72 ENST00000567512.1
sulfotransferase family 1A member 1
chr5_+_10250216 14.71 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr18_+_3451647 14.66 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr6_+_26103922 14.61 ENST00000377803.4
H4 clustered histone 3
chr1_+_13060769 14.59 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr19_-_39840671 14.57 ENST00000597224.5
fibrillarin
chr21_-_25735570 14.52 ENST00000400090.7
ENST00000400087.7
ENST00000400093.3
ATP synthase peripheral stalk subunit F6
chr18_+_9103959 14.46 ENST00000400033.1
NADH:ubiquinone oxidoreductase core subunit V2
chr20_+_3786772 14.43 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr14_+_55611977 14.42 ENST00000395309.7
ENST00000413890.6
kinectin 1
chr12_-_31326111 14.40 ENST00000539409.5
SIN3-HDAC complex associated factor
chr1_-_165768835 14.40 ENST00000481278.5
transmembrane and coiled-coil domains 1
chr19_-_45691771 14.37 ENST00000588599.5
ENST00000585392.2
ENST00000590212.1
ENST00000587367.5
ENST00000391932.7
ENST00000342669.8
small nuclear ribonucleoprotein D2 polypeptide
chr12_-_31326142 14.37 ENST00000337682.9
SIN3-HDAC complex associated factor
chr14_+_54397021 14.32 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr13_+_30427950 14.31 ENST00000436446.1
ubiquitin conjugating enzyme E2 L5
chr1_+_1013485 14.23 ENST00000649529.1
ISG15 ubiquitin like modifier
chr1_+_153774210 14.21 ENST00000271857.6
solute carrier family 27 member 3
chr10_-_56361235 14.20 ENST00000373944.8
ENST00000361148.6
ENST00000395405.5
ZW10 interacting kinetochore protein
chr3_+_172750715 14.20 ENST00000392692.8
ENST00000417960.5
ENST00000428567.5
ENST00000366090.6
ENST00000426894.5
epithelial cell transforming 2
chr1_-_150236150 14.08 ENST00000629042.2
acidic nuclear phosphoprotein 32 family member E
chr3_+_172750682 14.07 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr17_-_42018488 14.05 ENST00000589773.5
ENST00000674214.1
DnaJ heat shock protein family (Hsp40) member C7
chr19_+_17292583 14.04 ENST00000595444.1
ENST00000600434.5
mitochondrial ribosomal protein L34
chr17_+_68249200 14.04 ENST00000577985.5
archaelysin family metallopeptidase 2
chr17_-_79009778 14.03 ENST00000591773.5
ENST00000588611.5
ENST00000586916.6
ENST00000592033.5
ENST00000588075.5
ENST00000302345.6
ENST00000591811.1
calcium activated nucleotidase 1
chr11_-_88337722 14.02 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr5_+_83471668 14.01 ENST00000342785.8
ENST00000343200.9
versican
chr1_-_145405445 13.96 ENST00000620821.1
ENST00000369373.9
NBPF member 20
chr1_+_84479239 13.88 ENST00000370656.5
ENST00000370654.6
ribosome production factor 1 homolog
chr17_-_42136431 13.78 ENST00000552162.5
ENST00000550504.5
RAB5C, member RAS oncogene family
chr7_-_139132116 13.77 ENST00000680309.1
zinc finger CCCH-type containing, antiviral 1
chr6_-_149746497 13.77 ENST00000367404.8
ENST00000340413.7
ENST00000543637.1
nucleoporin 43
chr9_-_86100123 13.71 ENST00000388711.7
ENST00000466178.1
golgi membrane protein 1
chr8_-_123025627 13.71 ENST00000519018.5
derlin 1
chr1_-_11055820 13.64 ENST00000490101.1
spermidine synthase
chr1_+_40988513 13.63 ENST00000649215.1
CTP synthase 1
chr15_-_76311386 13.59 ENST00000560595.5
ENST00000433983.6
ENST00000559386.1
ENST00000559602.5
ENST00000560726.5
ENST00000557943.6
electron transfer flavoprotein subunit alpha
chr19_+_33374312 13.59 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr18_+_3447562 13.55 ENST00000618001.4
TGFB induced factor homeobox 1
chr2_+_159733958 13.54 ENST00000409591.5
membrane associated ring-CH-type finger 7
chr12_-_50025394 13.54 ENST00000454520.6
ENST00000546595.5
ENST00000548824.5
ENST00000549777.5
ENST00000546723.5
ENST00000427314.6
ENST00000552157.5
ENST00000552310.5
ENST00000548644.5
ENST00000546786.5
ENST00000550149.5
ENST00000546764.5
ENST00000552004.2
ENST00000548320.5
ENST00000312377.10
ENST00000547905.5
ENST00000550651.5
ENST00000551145.5
ENST00000552921.5
Rac GTPase activating protein 1
chr12_+_93467506 13.38 ENST00000549982.6
ENST00000552217.6
ENST00000393128.8
ENST00000547098.5
mitochondrial ribosomal protein L42
chr5_+_10250272 13.38 ENST00000280326.9
ENST00000625723.1
chaperonin containing TCP1 subunit 5
chr6_-_99568713 13.38 ENST00000520371.5
cyclin C
chr1_+_92832028 13.38 ENST00000370321.8
ENST00000645119.1
ribosomal protein L5
chr4_+_56977710 13.32 ENST00000450656.5
ENST00000381227.5
RNA polymerase II subunit B
chr1_-_150235995 13.08 ENST00000436748.6
acidic nuclear phosphoprotein 32 family member E
chr17_+_59209867 13.06 ENST00000578922.1
ENST00000300917.10
SMG8 nonsense mediated mRNA decay factor
chr14_+_54396949 13.05 ENST00000611205.4
cyclin dependent kinase inhibitor 3
chr4_+_146175702 13.04 ENST00000296581.11
ENST00000649747.1
ENST00000502781.5
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_99568611 13.03 ENST00000369217.8
ENST00000369220.8
ENST00000482541.2
ENST00000520429.6
ENST00000523985.5
ENST00000518714.5
cyclin C
chr7_-_29990113 13.02 ENST00000426154.5
ENST00000421434.5
ENST00000434476.6
secernin 1
chr3_-_197226351 12.96 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr2_-_151289613 12.95 ENST00000243346.10
N-myc and STAT interactor
chr3_-_108058361 12.91 ENST00000398258.7
CD47 molecule
chr7_+_118184156 12.85 ENST00000422760.1
ENST00000249299.7
ENST00000411938.1
LSM8 homolog, U6 small nuclear RNA associated
chr19_+_47130782 12.84 ENST00000597808.5
ENST00000413379.7
ENST00000600706.5
ENST00000270225.12
ENST00000598840.5
ENST00000600753.1
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr5_+_83471736 12.83 ENST00000265077.8
versican
chr15_+_89243945 12.82 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chrX_-_20218941 12.75 ENST00000457145.6
ribosomal protein S6 kinase A3
chr14_-_54488940 12.68 ENST00000628554.2
ENST00000358056.8
glia maturation factor beta
chr11_-_10807345 12.64 ENST00000525681.6
eukaryotic translation initiation factor 4 gamma 2
chr6_+_41787651 12.61 ENST00000398884.7
ENST00000398881.4
translocase of outer mitochondrial membrane 6
chr19_-_46846138 12.54 ENST00000597020.5
adaptor related protein complex 2 subunit sigma 1
chr8_-_70608407 12.48 ENST00000262213.7
translocation associated membrane protein 1
chr9_-_36276967 12.48 ENST00000396594.8
ENST00000543356.7
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 44.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
12.7 50.7 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
11.6 34.9 GO:1901421 positive regulation of response to alcohol(GO:1901421)
11.2 33.6 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
10.8 43.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
10.2 40.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
8.8 35.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
7.5 30.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
7.2 21.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
7.2 21.6 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
6.9 20.6 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
6.7 26.7 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
6.6 46.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
6.5 26.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
6.3 18.9 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
5.7 34.2 GO:0048254 snoRNA localization(GO:0048254)
5.5 77.0 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
5.4 37.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
5.3 74.8 GO:0051096 positive regulation of helicase activity(GO:0051096)
5.3 21.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
5.1 30.4 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
5.0 15.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
5.0 29.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
4.8 24.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
4.8 19.2 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
4.6 22.9 GO:0044111 development involved in symbiotic interaction(GO:0044111)
4.5 31.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
4.4 30.5 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
4.3 13.0 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) positive regulation of protein K48-linked ubiquitination(GO:1902524)
4.2 38.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
4.2 16.9 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
4.2 46.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
4.2 8.4 GO:0072019 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
4.2 33.4 GO:0006689 ganglioside catabolic process(GO:0006689)
4.2 20.8 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
4.1 20.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
4.1 24.3 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
4.0 24.0 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
4.0 23.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
3.9 19.6 GO:0031291 Ran protein signal transduction(GO:0031291)
3.9 27.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
3.9 15.6 GO:0006258 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of type B pancreatic cell development(GO:2000077)
3.9 15.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
3.8 11.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
3.7 29.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
3.6 10.8 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
3.6 18.0 GO:0030242 pexophagy(GO:0030242)
3.6 25.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
3.6 14.3 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
3.5 10.5 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
3.4 13.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
3.4 10.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
3.4 13.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
3.3 16.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
3.3 9.8 GO:0034729 histone H3-K79 methylation(GO:0034729)
3.3 26.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
3.3 26.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
3.2 19.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
3.2 6.4 GO:0099403 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
3.2 15.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
3.2 9.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
3.1 18.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
3.1 12.4 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
3.1 12.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
3.1 21.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
3.0 12.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
3.0 6.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
3.0 27.3 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
2.9 8.8 GO:0018094 protein polyglycylation(GO:0018094)
2.9 11.6 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
2.9 8.7 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
2.9 14.4 GO:0007144 female meiosis I(GO:0007144)
2.9 20.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
2.8 19.9 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
2.8 30.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.7 11.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
2.7 2.7 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
2.7 8.0 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
2.6 26.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
2.6 7.7 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
2.5 10.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
2.5 2.5 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
2.5 32.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
2.5 32.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.5 7.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
2.4 17.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.4 14.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
2.4 19.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.4 14.3 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
2.4 7.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
2.4 11.8 GO:0006177 GMP biosynthetic process(GO:0006177)
2.4 7.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
2.4 4.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
2.3 9.3 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.3 6.9 GO:0007518 myoblast fate determination(GO:0007518)
2.3 6.8 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
2.3 9.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
2.2 4.5 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
2.2 6.7 GO:0044565 dendritic cell proliferation(GO:0044565)
2.2 86.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.2 167.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.2 11.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
2.2 10.8 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.2 8.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
2.2 19.4 GO:0010265 SCF complex assembly(GO:0010265)
2.2 6.5 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
2.2 25.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.1 15.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
2.1 29.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.1 12.8 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255) UDP-glucuronate metabolic process(GO:0046398)
2.1 8.5 GO:0019323 pentose catabolic process(GO:0019323)
2.1 6.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.1 6.3 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
2.1 12.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
2.1 8.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.0 12.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
2.0 46.7 GO:0043968 histone H2A acetylation(GO:0043968)
2.0 22.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.0 8.0 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
2.0 18.0 GO:0006189 AMP biosynthetic process(GO:0006167) 'de novo' IMP biosynthetic process(GO:0006189)
2.0 8.0 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
2.0 6.0 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.0 7.9 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
2.0 17.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
2.0 5.9 GO:0006172 ADP biosynthetic process(GO:0006172)
2.0 17.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
2.0 29.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.9 21.4 GO:0042262 DNA protection(GO:0042262)
1.9 15.5 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.9 1.9 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.9 7.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
1.9 23.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.9 222.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
1.9 3.8 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.9 15.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
1.9 20.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.8 31.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.8 5.5 GO:0036089 cleavage furrow formation(GO:0036089)
1.8 7.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.8 3.6 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
1.8 23.3 GO:2000774 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
1.8 5.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.7 6.8 GO:0009956 radial pattern formation(GO:0009956)
1.7 6.8 GO:0048388 endosomal lumen acidification(GO:0048388)
1.7 8.4 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.7 11.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
1.7 15.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
1.7 5.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
1.7 5.0 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
1.6 27.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.6 32.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.6 1.6 GO:0060467 negative regulation of fertilization(GO:0060467)
1.6 14.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
1.6 8.0 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
1.6 25.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.6 20.7 GO:0000076 DNA replication checkpoint(GO:0000076)
1.6 11.0 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
1.6 23.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.6 7.8 GO:0060613 fat pad development(GO:0060613)
1.5 4.6 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
1.5 4.6 GO:0006041 glucosamine metabolic process(GO:0006041)
1.5 20.0 GO:0006983 ER overload response(GO:0006983)
1.5 6.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) deoxyribonucleoside diphosphate metabolic process(GO:0009186) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
1.5 4.6 GO:0036233 glycine import(GO:0036233)
1.5 9.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.5 19.5 GO:0070986 left/right axis specification(GO:0070986)
1.5 7.4 GO:0007386 compartment pattern specification(GO:0007386)
1.5 14.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.5 7.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
1.4 12.9 GO:0009249 protein lipoylation(GO:0009249)
1.4 34.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.4 8.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.4 15.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.4 5.6 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
1.4 58.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
1.4 8.2 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.4 24.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.4 26.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
1.4 44.8 GO:0019054 modulation by virus of host process(GO:0019054)
1.4 6.8 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.3 34.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.3 4.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.3 10.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.3 3.9 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.3 5.2 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.3 42.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.3 12.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.3 3.8 GO:0046521 sphingoid catabolic process(GO:0046521)
1.2 5.0 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.2 7.5 GO:0001880 Mullerian duct regression(GO:0001880)
1.2 7.4 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.2 4.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.2 7.3 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
1.2 4.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.2 9.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.2 6.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.2 3.5 GO:0016199 axon midline choice point recognition(GO:0016199)
1.2 20.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.2 3.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.2 9.3 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
1.2 5.8 GO:0006574 valine catabolic process(GO:0006574)
1.2 13.8 GO:0016540 protein autoprocessing(GO:0016540)
1.2 3.5 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
1.1 20.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.1 84.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.1 4.5 GO:0033606 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
1.1 22.6 GO:0051923 sulfation(GO:0051923)
1.1 4.4 GO:0050705 negative regulation of interleukin-1 alpha production(GO:0032690) regulation of interleukin-1 alpha secretion(GO:0050705) negative regulation of interleukin-1 alpha secretion(GO:0050712)
1.1 58.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.1 6.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.1 6.3 GO:0097338 response to clozapine(GO:0097338)
1.1 11.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.0 15.7 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
1.0 7.3 GO:0051382 kinetochore assembly(GO:0051382)
1.0 55.0 GO:0043486 histone exchange(GO:0043486)
1.0 3.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.0 7.2 GO:0072553 terminal button organization(GO:0072553)
1.0 6.1 GO:0061143 alveolar primary septum development(GO:0061143)
1.0 14.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
1.0 27.2 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
1.0 6.0 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.0 5.0 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
1.0 6.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
1.0 4.9 GO:0032596 protein transport into membrane raft(GO:0032596)
1.0 2.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
1.0 7.8 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
1.0 4.9 GO:0015862 uridine transport(GO:0015862)
1.0 6.8 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.0 20.2 GO:0008228 opsonization(GO:0008228)
1.0 4.8 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.0 17.2 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.0 8.6 GO:1905146 lysosomal protein catabolic process(GO:1905146)
1.0 64.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.0 2.9 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.9 2.8 GO:1903781 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of cardiac conduction(GO:1903781)
0.9 3.7 GO:0044821 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.9 2.8 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.9 2.8 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.9 3.7 GO:0035803 egg coat formation(GO:0035803)
0.9 5.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.9 3.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.9 16.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.9 5.4 GO:0035063 nuclear speck organization(GO:0035063)
0.9 4.5 GO:0006788 heme oxidation(GO:0006788)
0.9 10.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.9 14.9 GO:0030953 astral microtubule organization(GO:0030953)
0.9 71.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.9 11.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.9 12.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.9 9.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.9 12.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.8 15.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.8 2.5 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.8 6.7 GO:0042255 ribosome assembly(GO:0042255)
0.8 10.8 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.8 7.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.8 8.9 GO:0042373 vitamin K metabolic process(GO:0042373)
0.8 9.7 GO:0048368 lateral mesoderm development(GO:0048368)
0.8 4.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.8 20.1 GO:0030033 microvillus assembly(GO:0030033)
0.8 5.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.8 15.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.8 8.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.8 8.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.8 7.9 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.8 3.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.8 2.3 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.8 3.1 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.8 3.9 GO:0070383 DNA cytosine deamination(GO:0070383)
0.8 35.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.8 5.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.8 0.8 GO:0060300 regulation of cytokine activity(GO:0060300)
0.8 53.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.8 6.9 GO:0040016 embryonic cleavage(GO:0040016)
0.8 3.8 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.8 79.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.8 12.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.8 3.8 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.8 9.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.8 0.8 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.7 3.7 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.7 12.5 GO:0006012 galactose metabolic process(GO:0006012)
0.7 2.9 GO:2000254 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.7 5.1 GO:0061709 reticulophagy(GO:0061709)
0.7 11.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.7 1.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.7 4.3 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7 6.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.7 7.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.7 4.2 GO:0008218 bioluminescence(GO:0008218)
0.7 3.5 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.7 22.1 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.7 8.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.7 5.4 GO:0051026 chiasma assembly(GO:0051026)
0.7 8.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.7 3.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.7 4.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.7 13.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.7 10.7 GO:0070314 G1 to G0 transition(GO:0070314)
0.7 10.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.7 6.6 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.7 4.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 5.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.7 3.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.6 4.5 GO:1905068 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.6 2.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.6 6.4 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.6 2.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.6 12.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.6 7.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.6 3.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.6 5.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.6 9.4 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.6 1.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.6 10.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.6 1.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.6 9.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.6 16.6 GO:0016578 histone deubiquitination(GO:0016578)
0.6 1.8 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 8.2 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.6 4.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.6 0.6 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.6 47.9 GO:0006903 vesicle targeting(GO:0006903)
0.6 4.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.6 5.2 GO:0016559 peroxisome fission(GO:0016559)
0.6 2.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 27.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.6 4.0 GO:0032328 alanine transport(GO:0032328)
0.6 16.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.6 3.9 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.5 3.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.5 8.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.5 12.4 GO:0030728 ovulation(GO:0030728)
0.5 15.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.5 9.5 GO:0018208 peptidyl-proline modification(GO:0018208)
0.5 2.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.5 7.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.5 4.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.5 1.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.5 5.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 2.0 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 5.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.5 5.0 GO:0042659 regulation of cell fate specification(GO:0042659)
0.5 3.0 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.5 3.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.5 1.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.5 10.4 GO:0042026 protein refolding(GO:0042026)
0.5 2.9 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 3.4 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.5 3.4 GO:0003096 renal sodium ion transport(GO:0003096)
0.5 23.9 GO:0042348 regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.5 1.9 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.5 5.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.5 2.8 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.5 6.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 3.6 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.4 1.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.4 4.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.4 4.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 3.4 GO:0030578 PML body organization(GO:0030578)
0.4 5.6 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.4 15.2 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.4 2.5 GO:0051012 microtubule sliding(GO:0051012)
0.4 4.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 3.3 GO:0051451 myoblast migration(GO:0051451)
0.4 5.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.4 12.1 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.4 0.8 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.4 1.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4 0.8 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.4 4.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.4 38.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 13.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.4 2.3 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767)
0.4 3.0 GO:0032790 ribosome disassembly(GO:0032790)
0.4 1.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.4 6.0 GO:0003334 keratinocyte development(GO:0003334)
0.4 3.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.4 1.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.4 30.1 GO:0006413 translational initiation(GO:0006413)
0.4 5.4 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.4 3.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.4 1.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.4 3.2 GO:0098909 maintenance of centrosome location(GO:0051661) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 2.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.3 3.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 13.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 22.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.3 0.7 GO:0006550 isoleucine catabolic process(GO:0006550)
0.3 3.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 9.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 0.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 5.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.3 2.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 1.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 12.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 2.1 GO:0019321 pentose metabolic process(GO:0019321)
0.3 2.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 2.7 GO:0002934 desmosome organization(GO:0002934)
0.3 0.6 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.3 2.0 GO:0007143 female meiotic division(GO:0007143)
0.3 12.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 2.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 1.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 12.1 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.2 5.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 1.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.2 3.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 1.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 2.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 11.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.2 2.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 5.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 2.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 2.4 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2 2.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 28.7 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 0.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 3.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 1.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 4.9 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 2.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 5.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 0.4 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.2 7.4 GO:0006110 regulation of glycolytic process(GO:0006110)
0.2 0.7 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.2 5.9 GO:0014904 myotube cell development(GO:0014904)
0.2 12.7 GO:0016575 histone deacetylation(GO:0016575)
0.2 8.5 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.2 1.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
0.2 2.5 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.2 2.6 GO:1901661 quinone metabolic process(GO:1901661)
0.2 4.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 0.8 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.2 0.3 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.2 1.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.9 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.1 3.6 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 5.5 GO:0045333 cellular respiration(GO:0045333)
0.1 3.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.0 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 1.4 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 2.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 3.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 4.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 4.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 1.9 GO:0051712 regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.1 2.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 0.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 9.0 GO:0045931 positive regulation of mitotic cell cycle(GO:0045931)
0.1 0.6 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.7 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 1.7 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 0.4 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 9.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 4.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.8 GO:0007099 centriole replication(GO:0007099)
0.1 1.6 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 2.2 GO:0006491 N-glycan processing(GO:0006491)
0.1 5.6 GO:1903076 regulation of protein localization to plasma membrane(GO:1903076)
0.1 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.0 GO:0042428 serotonin metabolic process(GO:0042428)
0.1 6.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.6 GO:0046449 creatinine metabolic process(GO:0046449)
0.1 0.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.1 1.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 2.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 12.7 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 1.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 1.3 GO:0035329 hippo signaling(GO:0035329)
0.0 3.6 GO:0008380 RNA splicing(GO:0008380)
0.0 1.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:0021888 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.0 0.9 GO:0002076 osteoblast development(GO:0002076)
0.0 1.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861) negative regulation of glial cell migration(GO:1903976) regulation of microglial cell activation(GO:1903978) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.3 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331)
0.0 0.1 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.9 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.4 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 35.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
10.8 75.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
10.6 31.9 GO:0034515 proteasome storage granule(GO:0034515)
9.1 45.3 GO:0001651 dense fibrillar component(GO:0001651)
8.4 41.8 GO:0097149 centralspindlin complex(GO:0097149)
6.9 41.5 GO:0000243 commitment complex(GO:0000243)
6.8 40.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
6.5 19.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
6.0 24.0 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
5.9 77.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
5.8 34.7 GO:0009368 endopeptidase Clp complex(GO:0009368)
5.5 71.1 GO:0005688 U6 snRNP(GO:0005688)
5.5 27.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
5.4 37.9 GO:0044326 dendritic spine neck(GO:0044326)
5.3 26.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
5.1 15.2 GO:0031262 Ndc80 complex(GO:0031262)
4.8 19.3 GO:1990423 RZZ complex(GO:1990423)
4.7 65.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
4.7 37.2 GO:0005827 polar microtubule(GO:0005827)
4.6 23.2 GO:0032301 MutSalpha complex(GO:0032301)
4.5 18.1 GO:0005687 U4 snRNP(GO:0005687)
4.4 26.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
4.3 30.4 GO:0044530 supraspliceosomal complex(GO:0044530)
3.9 15.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
3.9 23.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
3.8 11.3 GO:0055087 Ski complex(GO:0055087)
3.7 11.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.6 10.8 GO:0002081 outer acrosomal membrane(GO:0002081)
3.6 10.8 GO:0097441 basilar dendrite(GO:0097441)
3.6 28.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.6 17.8 GO:0033503 HULC complex(GO:0033503)
3.4 94.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
3.3 3.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
3.3 22.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
3.2 19.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
3.2 19.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
3.2 60.5 GO:0000812 Swr1 complex(GO:0000812)
3.2 28.5 GO:0034709 methylosome(GO:0034709)
3.2 9.5 GO:0016939 kinesin II complex(GO:0016939)
3.1 61.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
3.0 60.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
3.0 35.6 GO:0071203 WASH complex(GO:0071203)
3.0 17.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
3.0 11.8 GO:0071942 XPC complex(GO:0071942)
2.9 23.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
2.9 14.5 GO:0070557 PCNA-p21 complex(GO:0070557)
2.8 13.8 GO:0031523 Myb complex(GO:0031523)
2.7 10.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
2.6 7.7 GO:0000799 nuclear condensin complex(GO:0000799)
2.6 7.7 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
2.5 12.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
2.5 19.8 GO:0008290 F-actin capping protein complex(GO:0008290)
2.5 27.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.3 11.7 GO:0031673 H zone(GO:0031673)
2.3 28.0 GO:0042555 MCM complex(GO:0042555)
2.3 7.0 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
2.3 20.8 GO:0031298 replication fork protection complex(GO:0031298)
2.3 29.9 GO:0033093 Weibel-Palade body(GO:0033093)
2.3 29.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.2 26.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.2 15.4 GO:0000125 PCAF complex(GO:0000125)
2.2 10.8 GO:0005663 DNA replication factor C complex(GO:0005663)
2.1 6.4 GO:0031933 telomeric heterochromatin(GO:0031933)
2.1 6.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
2.1 56.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
2.0 40.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
2.0 9.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.9 9.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.9 11.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.9 7.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.8 1.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.8 18.3 GO:0070552 BRISC complex(GO:0070552)
1.8 5.3 GO:0005873 plus-end kinesin complex(GO:0005873)
1.7 22.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.7 10.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.7 11.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.7 8.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
1.7 14.9 GO:0000813 ESCRT I complex(GO:0000813)
1.7 26.4 GO:0005642 annulate lamellae(GO:0005642)
1.6 1.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
1.6 233.1 GO:0015934 large ribosomal subunit(GO:0015934)
1.6 11.0 GO:0030905 retromer, tubulation complex(GO:0030905)
1.6 15.7 GO:0061574 ASAP complex(GO:0061574)
1.6 34.4 GO:0036020 endolysosome membrane(GO:0036020)
1.6 31.3 GO:0035371 microtubule plus-end(GO:0035371)
1.5 10.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.5 7.3 GO:0044308 axonal spine(GO:0044308)
1.5 7.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.5 5.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.4 15.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.4 10.1 GO:1990761 growth cone lamellipodium(GO:1990761)
1.4 7.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.4 5.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
1.4 9.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
1.4 16.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.3 4.0 GO:0005685 U1 snRNP(GO:0005685)
1.3 21.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.3 22.4 GO:0036452 ESCRT complex(GO:0036452)
1.3 5.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
1.3 14.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.3 20.4 GO:0031932 TORC2 complex(GO:0031932)
1.3 59.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.3 5.0 GO:0034457 Mpp10 complex(GO:0034457)
1.2 11.0 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.1 18.3 GO:0031080 nuclear pore outer ring(GO:0031080)
1.1 14.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.1 11.2 GO:0005869 dynactin complex(GO:0005869)
1.1 4.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
1.0 7.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.0 3.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.0 18.5 GO:0030056 hemidesmosome(GO:0030056)
1.0 9.2 GO:0070765 gamma-secretase complex(GO:0070765)
1.0 8.0 GO:0097443 sorting endosome(GO:0097443)
1.0 6.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.9 23.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.9 23.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.9 7.1 GO:0030478 actin cap(GO:0030478)
0.9 162.8 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.9 18.2 GO:0030686 90S preribosome(GO:0030686)
0.9 13.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 5.9 GO:0030891 VCB complex(GO:0030891)
0.8 5.9 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.8 7.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.8 4.8 GO:0090543 Flemming body(GO:0090543)
0.8 43.4 GO:0002102 podosome(GO:0002102)
0.8 3.2 GO:0044307 dendritic branch(GO:0044307)
0.8 11.0 GO:0051233 spindle midzone(GO:0051233)
0.8 10.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.8 20.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.8 6.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.8 25.2 GO:0035861 site of double-strand break(GO:0035861)
0.7 17.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.7 8.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.7 3.7 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.7 15.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 12.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 32.8 GO:0005876 spindle microtubule(GO:0005876)
0.7 10.2 GO:0000242 pericentriolar material(GO:0000242)
0.7 8.0 GO:0071438 invadopodium membrane(GO:0071438)
0.7 6.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.6 46.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.6 4.4 GO:0036157 outer dynein arm(GO:0036157)
0.6 5.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.6 3.6 GO:0098576 lumenal side of membrane(GO:0098576)
0.6 1.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 25.1 GO:0016235 aggresome(GO:0016235)
0.6 2.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.6 2.8 GO:0030314 junctional membrane complex(GO:0030314)
0.6 11.6 GO:0043219 lateral loop(GO:0043219)
0.6 5.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.6 13.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 2.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5 2.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.5 10.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.5 31.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5 93.8 GO:0005681 spliceosomal complex(GO:0005681)
0.5 16.9 GO:0071564 npBAF complex(GO:0071564)
0.5 4.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5 5.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 5.4 GO:0070938 contractile ring(GO:0070938)
0.5 15.6 GO:0072686 mitotic spindle(GO:0072686)
0.5 52.5 GO:0030496 midbody(GO:0030496)
0.5 5.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.5 4.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.5 49.0 GO:0000922 spindle pole(GO:0000922)
0.5 79.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.5 20.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5 2.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.5 16.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 38.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.4 4.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.4 2.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.4 2.2 GO:0032044 DSIF complex(GO:0032044)
0.4 27.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 4.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 6.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 2.1 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.4 52.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 4.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 1.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.4 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 8.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3 4.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 19.4 GO:0031519 PcG protein complex(GO:0031519)
0.3 18.8 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.3 5.6 GO:0008091 spectrin(GO:0008091)
0.3 17.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627) ribosomal subunit(GO:0044391)
0.3 3.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 9.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 9.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 3.7 GO:0032433 filopodium tip(GO:0032433)
0.3 5.2 GO:0071141 SMAD protein complex(GO:0071141)
0.3 1.5 GO:0070761 pre-snoRNP complex(GO:0070761)
0.3 3.1 GO:0016342 catenin complex(GO:0016342)
0.3 21.6 GO:0005819 spindle(GO:0005819)
0.3 7.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 12.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 21.1 GO:0000793 condensed chromosome(GO:0000793)
0.3 10.1 GO:0005840 ribosome(GO:0005840)
0.3 2.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 4.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 12.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 0.7 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 8.4 GO:0008180 COP9 signalosome(GO:0008180)
0.2 19.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 27.4 GO:0016605 PML body(GO:0016605)
0.2 4.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 2.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 3.4 GO:0005922 connexon complex(GO:0005922)
0.2 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 8.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.2 75.1 GO:0005925 focal adhesion(GO:0005925)
0.2 53.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 15.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 0.5 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 13.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.3 GO:0000938 GARP complex(GO:0000938)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 14.9 GO:0042581 specific granule(GO:0042581)
0.1 5.0 GO:0031201 SNARE complex(GO:0031201)
0.1 1.6 GO:0005921 gap junction(GO:0005921)
0.1 2.9 GO:0031904 endosome lumen(GO:0031904)
0.1 2.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0005915 zonula adherens(GO:0005915)
0.1 3.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 4.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.1 6.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 3.0 GO:0032420 stereocilium(GO:0032420)
0.1 1.4 GO:0000786 nucleosome(GO:0000786)
0.1 2.4 GO:0015030 Cajal body(GO:0015030)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 26.2 GO:0016607 nuclear speck(GO:0016607)
0.1 12.1 GO:0001726 ruffle(GO:0001726)
0.1 0.8 GO:0031941 filamentous actin(GO:0031941)
0.1 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 1.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 3.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 4.7 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.0 5.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.6 40.9 GO:0003896 DNA primase activity(GO:0003896)
12.2 48.8 GO:0030622 U4atac snRNA binding(GO:0030622)
12.2 72.9 GO:1990446 U1 snRNP binding(GO:1990446)
11.2 33.6 GO:0031208 POZ domain binding(GO:0031208)
11.1 66.3 GO:0019238 cyclohydrolase activity(GO:0019238)
10.8 43.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
9.8 29.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
9.3 46.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
8.4 25.1 GO:0004766 spermidine synthase activity(GO:0004766)
7.4 73.7 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
7.0 21.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
6.2 43.1 GO:0004849 uridine kinase activity(GO:0004849)
5.9 29.6 GO:0030621 U4 snRNA binding(GO:0030621)
5.7 22.6 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
5.4 16.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
5.3 15.8 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
5.2 41.4 GO:0019237 centromeric DNA binding(GO:0019237)
5.0 15.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
5.0 15.0 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
4.8 28.5 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
4.7 18.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
4.5 26.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
4.3 25.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
4.1 12.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
3.9 11.6 GO:0032143 single thymine insertion binding(GO:0032143)
3.7 11.2 GO:0000035 acyl binding(GO:0000035)
3.7 29.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.6 10.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
3.6 10.9 GO:0001069 regulatory region RNA binding(GO:0001069)
3.6 14.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
3.6 28.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
3.5 27.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
3.4 17.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
3.4 13.6 GO:0003883 CTP synthase activity(GO:0003883)
3.3 10.0 GO:0032089 NACHT domain binding(GO:0032089)
3.3 92.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.3 39.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
3.3 58.5 GO:0001055 RNA polymerase II activity(GO:0001055)
3.2 12.8 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.1 25.1 GO:0004111 creatine kinase activity(GO:0004111)
3.1 6.1 GO:0009041 uridylate kinase activity(GO:0009041)
3.0 27.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
3.0 15.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
3.0 11.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
2.9 8.8 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.9 14.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
2.8 8.5 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
2.8 8.4 GO:0008169 C-methyltransferase activity(GO:0008169)
2.6 10.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.6 20.7 GO:0019863 IgE binding(GO:0019863)
2.6 7.7 GO:0002135 CTP binding(GO:0002135)
2.6 15.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
2.6 23.1 GO:0016842 amidine-lyase activity(GO:0016842)
2.6 20.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.5 20.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
2.5 2.5 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
2.5 7.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
2.4 9.5 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
2.4 9.5 GO:0043273 CTPase activity(GO:0043273)
2.4 11.8 GO:0042296 ISG15 transferase activity(GO:0042296)
2.4 7.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
2.3 15.9 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
2.2 85.4 GO:0005540 hyaluronic acid binding(GO:0005540)
2.2 6.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
2.2 19.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
2.2 6.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
2.2 6.6 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
2.2 11.0 GO:1990460 leptin receptor binding(GO:1990460)
2.2 28.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.1 15.0 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
2.1 12.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
2.1 25.4 GO:0015266 protein channel activity(GO:0015266)
2.1 6.4 GO:0015616 DNA translocase activity(GO:0015616)
2.1 6.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
2.1 8.4 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
2.0 4.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
2.0 16.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
2.0 8.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.0 13.8 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.9 7.7 GO:0043515 kinetochore binding(GO:0043515)
1.9 5.8 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
1.9 21.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
1.8 7.3 GO:0033265 choline binding(GO:0033265)
1.8 7.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.8 16.1 GO:0032190 acrosin binding(GO:0032190)
1.8 35.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.7 12.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.7 29.3 GO:0051400 BH domain binding(GO:0051400)
1.7 25.9 GO:0017070 U6 snRNA binding(GO:0017070)
1.7 25.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.7 5.0 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
1.7 36.6 GO:0008494 translation activator activity(GO:0008494)
1.7 5.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.7 8.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
1.6 4.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.6 30.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.6 6.5 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
1.6 16.0 GO:0051425 PTB domain binding(GO:0051425)
1.6 14.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.6 28.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.6 4.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.6 6.2 GO:0016417 S-acyltransferase activity(GO:0016417)
1.5 4.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.5 33.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
1.5 34.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.5 9.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.5 44.7 GO:0070410 co-SMAD binding(GO:0070410)
1.5 8.9 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.4 1.4 GO:0032427 GBD domain binding(GO:0032427)
1.4 4.3 GO:0008384 IkappaB kinase activity(GO:0008384)
1.4 8.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
1.4 24.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.4 34.8 GO:0031489 myosin V binding(GO:0031489)
1.4 6.9 GO:0050436 microfibril binding(GO:0050436)
1.4 11.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.4 12.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.4 49.0 GO:0001671 ATPase activator activity(GO:0001671)
1.3 12.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.3 9.3 GO:0016403 dimethylargininase activity(GO:0016403)
1.3 8.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.3 9.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.3 3.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.2 5.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.2 49.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.2 7.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
1.2 42.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.2 7.3 GO:0004594 pantothenate kinase activity(GO:0004594)
1.2 4.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.2 17.0 GO:0031386 protein tag(GO:0031386)
1.2 251.0 GO:0003735 structural constituent of ribosome(GO:0003735)
1.2 50.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
1.2 31.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.2 8.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.2 10.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.2 3.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.1 3.3 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.1 62.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
1.1 6.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
1.1 19.4 GO:0097602 cullin family protein binding(GO:0097602)
1.1 3.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.1 4.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.1 12.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.0 3.1 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
1.0 11.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.0 36.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.0 4.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.0 4.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.0 18.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.0 32.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
1.0 13.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.0 14.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
1.0 2.9 GO:0004958 prostaglandin F receptor activity(GO:0004958)
1.0 20.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
1.0 11.6 GO:0004526 ribonuclease P activity(GO:0004526)
1.0 11.6 GO:0003688 DNA replication origin binding(GO:0003688)
1.0 2.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.0 9.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9 17.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.9 20.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.9 2.8 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.9 19.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.9 16.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.9 5.6 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.9 4.6 GO:0003678 DNA helicase activity(GO:0003678)
0.9 4.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.9 4.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 7.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.9 26.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.9 52.7 GO:0019894 kinesin binding(GO:0019894)
0.8 21.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.8 48.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.8 8.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.8 67.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.8 28.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.8 8.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.8 21.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.8 2.4 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.8 8.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 6.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.8 5.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.8 3.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.8 3.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.8 22.5 GO:0070840 dynein complex binding(GO:0070840)
0.8 13.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.8 5.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.8 13.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 8.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.7 5.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.7 20.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.7 4.4 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.7 3.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 10.7 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.7 2.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.7 4.3 GO:0017040 ceramidase activity(GO:0017040)
0.7 6.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.7 5.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.7 34.9 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.7 6.3 GO:0045545 syndecan binding(GO:0045545)
0.7 5.6 GO:0042731 PH domain binding(GO:0042731)
0.7 6.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 2.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.7 14.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 4.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.6 4.5 GO:0000150 recombinase activity(GO:0000150)
0.6 7.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.6 17.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.6 4.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 75.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.6 8.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.6 1.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.6 10.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.6 2.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6 26.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.6 2.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.6 10.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 3.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.5 2.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.5 9.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.5 3.8 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 3.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.5 13.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.5 2.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.5 3.6 GO:0042608 T cell receptor binding(GO:0042608)
0.5 3.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 12.0 GO:0008301 DNA binding, bending(GO:0008301)
0.5 6.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.9 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 34.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.5 5.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.5 4.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 11.1 GO:0070064 proline-rich region binding(GO:0070064)
0.5 3.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.5 8.7 GO:0043422 protein kinase B binding(GO:0043422)
0.5 29.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 3.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 5.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4 7.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.4 12.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 5.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 4.3 GO:0017069 snRNA binding(GO:0017069)
0.4 8.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 173.0 GO:0045296 cadherin binding(GO:0045296)
0.4 1.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 3.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 5.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 9.3 GO:0004532 exoribonuclease activity(GO:0004532)
0.4 4.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 14.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 69.8 GO:0042393 histone binding(GO:0042393)
0.4 7.3 GO:0030515 snoRNA binding(GO:0030515)
0.4 16.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.4 7.2 GO:0035497 cAMP response element binding(GO:0035497)
0.4 1.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4 13.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 1.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 3.1 GO:0070697 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.4 3.0 GO:0030274 LIM domain binding(GO:0030274)
0.4 2.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 8.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.4 5.1 GO:0031996 thioesterase binding(GO:0031996)
0.4 18.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 6.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 1.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.3 23.0 GO:0019003 GDP binding(GO:0019003)
0.3 5.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 2.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 3.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 4.6 GO:0031014 troponin T binding(GO:0031014)
0.3 23.3 GO:0008565 protein transporter activity(GO:0008565)
0.3 2.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 34.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 2.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 4.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 4.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 16.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 3.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 3.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 5.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 2.0 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.3 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 7.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.3 2.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 2.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 5.7 GO:0008242 omega peptidase activity(GO:0008242)
0.3 7.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 4.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 5.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 4.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 43.4 GO:0051015 actin filament binding(GO:0051015)
0.3 4.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 1.8 GO:1990405 C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405)
0.3 3.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 19.3 GO:0043130 ubiquitin binding(GO:0043130)
0.3 0.8 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 1.5 GO:0039552 RIG-I binding(GO:0039552)
0.2 10.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 0.7 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.2 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.2 0.7 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.2 2.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 8.8 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 0.5 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.2 0.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 3.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 2.7 GO:0004386 helicase activity(GO:0004386)
0.2 3.0 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.2 3.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 7.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 7.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 2.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.7 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 8.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.0 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 1.3 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 133.4 GO:0003723 RNA binding(GO:0003723)
0.1 1.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 5.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 3.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.0 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.3 GO:0005112 Notch binding(GO:0005112)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 6.7 GO:0002020 protease binding(GO:0002020)
0.1 1.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 5.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.8 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.1 1.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 6.1 GO:0003924 GTPase activity(GO:0003924)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 84.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.1 28.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.6 46.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.5 10.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.4 84.4 PID AURORA B PATHWAY Aurora B signaling
1.3 52.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.2 23.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.2 94.1 PID P53 REGULATION PATHWAY p53 pathway
1.1 35.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.0 56.7 PID ATR PATHWAY ATR signaling pathway
0.9 19.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.9 21.9 PID ARF 3PATHWAY Arf1 pathway
0.9 9.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.8 35.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.8 79.2 PID E2F PATHWAY E2F transcription factor network
0.7 14.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.7 73.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.7 46.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.7 48.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.7 18.0 PID MYC PATHWAY C-MYC pathway
0.7 31.4 PID PLK1 PATHWAY PLK1 signaling events
0.7 12.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.6 5.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.5 30.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.5 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.5 31.3 PID NOTCH PATHWAY Notch signaling pathway
0.5 20.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 16.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.4 7.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 9.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 10.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 18.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.4 7.5 PID ALK2 PATHWAY ALK2 signaling events
0.4 25.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.4 22.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 11.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 19.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 9.7 PID RHOA PATHWAY RhoA signaling pathway
0.3 8.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 14.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 3.3 PID ATM PATHWAY ATM pathway
0.2 11.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 8.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 9.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 4.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 9.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 2.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 9.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 5.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 5.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 4.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 2.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 2.4 PID AURORA A PATHWAY Aurora A signaling
0.2 8.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 4.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 10.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 8.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 14.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.0 PID FGF PATHWAY FGF signaling pathway
0.1 3.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.2 PID FOXO PATHWAY FoxO family signaling
0.1 3.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 2.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 73.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
3.2 51.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
2.8 14.0 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
2.7 5.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
2.7 21.6 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
2.6 23.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
2.5 58.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
2.5 95.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
2.5 37.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
2.4 26.5 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
2.4 9.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
2.3 233.5 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
2.3 34.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.3 54.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
2.2 19.4 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
2.1 14.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
2.1 31.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
2.1 59.1 REACTOME KINESINS Genes involved in Kinesins
1.9 19.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
1.9 45.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.8 22.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.6 4.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
1.6 77.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.5 77.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
1.5 128.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.5 33.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.4 27.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
1.4 21.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.3 24.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.3 34.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.3 26.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.3 39.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.2 38.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.2 38.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.2 22.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.2 176.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
1.1 39.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
1.1 20.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.1 96.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.1 26.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.1 19.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.1 17.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.0 67.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.0 11.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.0 16.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.9 20.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.9 35.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.9 14.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.8 21.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.8 44.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.8 12.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.8 3.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.8 23.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7 8.2 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.7 22.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.7 11.7 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.7 10.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.7 100.8 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.7 6.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.7 9.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.7 22.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.7 11.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.7 8.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.7 7.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.6 10.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 13.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 3.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.6 100.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.6 10.2 REACTOME S PHASE Genes involved in S Phase
0.6 14.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.6 4.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.6 10.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.6 28.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.6 27.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 9.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.6 15.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.5 6.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.5 6.3 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.5 7.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5 18.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.5 11.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.5 10.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.5 7.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.5 35.7 REACTOME TRANSLATION Genes involved in Translation
0.5 5.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 10.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 8.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 12.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.5 6.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4 10.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 6.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 16.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 3.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 22.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 12.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 9.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 10.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 5.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 8.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.3 8.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 7.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.3 9.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 4.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 3.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 12.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 2.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 16.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.2 6.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 3.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 3.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 2.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 4.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 5.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 6.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 4.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 7.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 4.4 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.2 8.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.8 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 5.2 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 2.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 7.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 5.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.6 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 0.9 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 3.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis