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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CACCUCC

Z-value: 0.09

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miRNA associated with seed CACCUCC

NamemiRBASE accession
hsa-miR-1306-5p
MIMAT0022726

Activity profile of CACCUCC motif

Sorted Z-values of CACCUCC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CACCUCC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_176365455 0.51 ENST00000310389.6
ARL10
ADP ribosylation factor like GTPase 10
chr9_-_98708856 0.45 ENST00000259455.4
GABBR2
gamma-aminobutyric acid type B receptor subunit 2
chr1_+_46489800 0.40 ENST00000360032.4
DMBX1
diencephalon/mesencephalon homeobox 1
chr11_-_45665578 0.30 ENST00000308064.7
CHST1
carbohydrate sulfotransferase 1
chr8_+_11284789 0.28 ENST00000221086.8
MTMR9
myotubularin related protein 9
chr22_+_39994926 0.26 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr9_-_128067310 0.22 ENST00000373078.5
NAIF1
nuclear apoptosis inducing factor 1
chr1_+_19312296 0.22 ENST00000375155.7
ENST00000375153.8
SLC66A1
solute carrier family 66 member 1
chr14_-_77377046 0.20 ENST00000216468.8
TMED8
transmembrane p24 trafficking protein family member 8
chr22_-_44312894 0.19 ENST00000381176.5
SHISAL1
shisa like 1
chr8_+_55102012 0.17 ENST00000327381.7
XKR4
XK related 4
chr22_-_38872206 0.15 ENST00000407418.8
ENST00000216083.6
CBX6
chromobox 6
chr11_-_64803152 0.15 ENST00000439069.5
ENST00000294066.7
ENST00000377350.7
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr19_+_1450113 0.15 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC2
APC regulator of WNT signaling pathway 2
chr16_-_66550142 0.15 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
TK2
thymidine kinase 2
chr2_-_168247569 0.14 ENST00000355999.5
STK39
serine/threonine kinase 39
chr2_+_73984902 0.13 ENST00000409262.8
TET3
tet methylcytosine dioxygenase 3
chr2_-_25252251 0.11 ENST00000380746.8
ENST00000402667.1
DNMT3A
DNA methyltransferase 3 alpha
chr15_-_34210073 0.11 ENST00000559515.1
ENST00000560108.5
ENST00000256544.8
ENST00000559462.1
KATNBL1
katanin regulatory subunit B1 like 1
chr15_-_73368951 0.06 ENST00000261917.4
HCN4
hyperpolarization activated cyclic nucleotide gated potassium channel 4
chr14_+_23306816 0.05 ENST00000678311.1
ENST00000557579.2
ENST00000250405.10
ENST00000679000.1
ENST00000557236.6
ENST00000678502.1
ENST00000553781.5
BCL2L2
BCL2L2-PABPN1
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr9_+_35749274 0.05 ENST00000378078.5
RGP1
RGP1 homolog, RAB6A GEF complex partner 1
chr7_-_139777986 0.04 ENST00000406875.8
HIPK2
homeodomain interacting protein kinase 2
chr9_-_71121596 0.04 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
TRPM3
transient receptor potential cation channel subfamily M member 3
chr15_+_90001300 0.02 ENST00000268154.9
ZNF710
zinc finger protein 710
chr3_-_48430045 0.01 ENST00000296440.11
PLXNB1
plexin B1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)