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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for CEBPG
Z-value: 0.69
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Transcription factors associated with CEBPG
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CEBPG | hg38_v1_chr19_+_33373694_33373826, hg38_v1_chr19_+_33374312_33374348 | -0.37 | 1.6e-08 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of CEBPG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 22.0 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 6.7 | 20.1 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 0.2 | 14.2 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 1.0 | 11.9 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.4 | 9.4 | GO:0006907 | pinocytosis(GO:0006907) |
| 2.1 | 8.5 | GO:1903610 | regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634) |
| 0.7 | 8.1 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 2.5 | 7.5 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 2.5 | 7.4 | GO:0019836 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.7 | 7.4 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 37.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 6.9 | 27.6 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 26.7 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 22.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 13.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.5 | 13.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 12.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.7 | 8.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 8.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.9 | 6.6 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.1 | 35.6 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.1 | 29.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.3 | 23.1 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 12.8 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 10.8 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 2.1 | 8.5 | GO:0004341 | gluconolactonase activity(GO:0004341) |
| 0.3 | 8.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 8.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 7.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.7 | 7.4 | GO:0004568 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.3 | 15.1 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.3 | 13.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 9.4 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 7.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 5.1 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 3.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 2.8 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 2.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 2.3 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.1 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.9 | 17.8 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.7 | 17.2 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.8 | 13.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.3 | 7.2 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.3 | 6.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.2 | 5.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 5.4 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.1 | 4.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 4.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |